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      • KCI등재

        Evaluation of Microstructure, Mechanical and Thermal Properties of Ti–Zr–Pd–Cu and Ti–Zr–Pd–Cu–Bi Nanoglass Thin Films

        Maryam Mohri,Mohammed Renda Chellali,Di Wang,Julia Ivanisenko 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.7

        High entropy alloy thin films have been gained attention recently due to their exceptional properties like high corrosion resistance,unique mechanical and physical properties. In this research, DC magnetron sputtering was used to fabricate two kindsof high entropy alloys thin films of Ti–Zr–Pd–Cu and Ti–Zr–Pd–Cu–Bi at two working pressure 2 and 5 mTorr. Structural,thermal, and mechanical properties of the Ti–Zr–Pd–Cu and Ti–Zr–Pd–Cu–Bi thin films deposited at room temperature usingDC magnetron sputtering have been considered in this research. The microstructural analyses using X-ray diffractometer,scanning, and transmission electron microscopies show that the size of glassy clusters and the chemical composition of thinfilms can be controlled by adjusting the sputtering pressure. The high entropy alloy thin films deposited at high pressuredisplayed nano-clusters with an amorphous structure. The elemental distribution obtained using atom probe tomographyillustrated that Bi atoms were segregated along with the columnar interfaces. Furthermore, Bi addition to the Ti–Zr–Pd–Cuthin film led to increase in thermal stability and decrease in the characteristic enthalpy of the nanoglass thin films. The thinfilms’ mechanical properties were evaluated by nano-indentation. The results indicated that the Ti–Zr–Pd–Cu–Bi nanoglassthin film had higher strength, hardness, and elastic modulus than the Ti–Zr–Cu–Pd thin film. It was suggested that latticedistortion and nano columnar structure caused to increase in the mechanical properties of Ti–Zr–Pd–Cu–Bi thin film.

      • Tourism

        Maryam,Salmanian,Arezoo,Golkar,Mozafar Mohammadkhani,jafar,Safakhah 세계문화관광학회 2010 Conference Proceedings Vol.11 No.0

        According to tourism international organization report, countries income made by tourism has been increasingly developed in recent years. Nowadays tourism is the main power of economic development and growth in many countries and it diversifies the economy by providing opportunities and brings employment and income. According to statistics reported by this organization, tourism is of the main world industries next to oil and machinery industries and has had great role in solving economic problems by for example providing employment and income. This industry has been on main interest of governors in terms of macro investment due to its low cost and it is attempted to identify it. Our country in spite of having high capacities, has failed to keep pace with this growth and develop its internal and external tourism industry. In this study it is attempts to examine Iran‘s status with regard the fact that it has rich valuable natural and cultural treasuries by analyzing tourism importance in different countries. In addition, some recommendations are provided in order to improve some kinds of tourism which are more suitable for Iran with regard to its cultural and religious situation.

      • KCI등재

        Effects of Serum Vitamin D and Efficacy of Subcutaneous Immunotherapy in Adult Patients With Allergic Rhinitis

        Maryam Joudi,Reza Farid Hosseini,Maryam Khoshkhui,Maryam Salehi,Samaneh Kouzegaran,Mansur Ahoon,Farahzad Jabbari Azad 대한천식알레르기학회 2019 Allergy, Asthma & Immunology Research Vol.11 No.6

        Immunotherapy is the standard of treatment for long-life relief of symptoms of allergic rhinitis. Vitamin D may affect the outcomes of treatment. This study evaluated the clinical efficacy of subcutaneous allergen immunotherapy in adult patients with allergic rhinitis based on the serum level of vitamin D. Patients with persistent allergic rhinitis and positivity for skin prick test were evaluated by Sino-nasal Outcome Test (SNOT-22) and Mini Rhinoconjunctivitis Quality of Life Questionnaire (MiniRQLQ) before subcutaneous allergen immunotherapy and during the maintenance phase to assess the relation of the serum level of vitamin D and the clinical efficacy of immunotherapy. After immunotherapy, the greatest reduction in SNOT-22 scores were reported in patients with vitamin D sufficiency (39.0 ± 9.2), followed by vitamin D suboptimal provision (35.1 ± 12.1), insufficiency (25.0 ± 7.5), and deficiency (18.3 ± 6.0) (P < 0.001). The MiniRQLQ reduction in patients with vitamin D sufficiency, suboptimal provision, insufficiency, or deficiency was 30.7 ± 8.7, 27.1 ± 8.7, 20.0 ± 8.6, or 17.4 ± 7.1, respectively (P < 0.001). Both of SNOT-22 and MiniRQLQ scores decreased significantly following immunotherapy in patients with different levels of vitamin D. However, these effects were more pronounced when the level of vitamin D was sufficient.

      • KCI등재

        The association of pro-oxidant/antioxidant balance and blood parameters in patients with beta-thalassemia major: a cross-sectional study

        Maryam Parvizi,Maryam Deldadeh Moghaddam,Shiva Nazari,Hami Ashraf,Maryam Kazemi Aghdam 대한혈액학회 2023 Blood Research Vol.58 No.4

        Background Oxidative stress due to iron accumulation in patients with beta-thalassemia major (BTM) causes complications such as tissue damage and destruction. This study aimed to assess the association between the serum prooxidant/antioxidant balance (PAB) and blood parameters in patients with BTM. Methods This cross-sectional study included 92 patients with BTM. In this study, PAB was measured using an enzyme-linked immunosorbent assay (ELISA). Serum ferritin, blood urea nitrogen (BUN), creatinine (Cr), alanine aminotransferase (ALT), aspartate aminotransferase (AST), thyroid-stimulating hormone (TSH), total cholesterol (TC), triglyceride (TG), complete blood cell count (CBC), and history of blood transfusion were recorded. The association of the blood parameters was assessed across the tertiles (T) of serum PAB (highest T vs. lowest T). Results The results showed that high serum ferritin was directly associated with serum PAB [odds ratio (OR), 12.80; 95% confidence interval (CI), 2.98‒54.91; T3 vs. T1]. Also, direct associations were found for high TC (OR, 4.97; 95% CI, 1.42‒17.32; T3 vs. T1), high ALT (OR, 4.95; 95% CI, 1.33‒18.46; T3 vs. T1) and high TSH (OR, 3.78; 95% CI, 1.10‒13.02; T3 vs. T1). Conclusion The findings of the present study showed that serum PAB levels were directly associated with ferritin, ALT, TC, and TSH levels. This indicates that improvements in blood parameters, especially ferritin and TSH levels, occur by ameliorating oxidative stress in patients with BTM.

      • KCI등재

        Effect of Cucumber Mycorrhiza Inoculation under Low and High Root Temperature Grown on Hydroponic Conditions

        Maryam Haghighi,Maryam Mozafariyan,Behzad Abdolahipour 한국작물학회 2015 Journal of crop science and biotechnology Vol.18 No.2

        Cucumber is a subtropical vegetable sensitive to high and low root temperature. Additionally, mycorrhiza with beneficial effect on plant growth can increase plant tolerance to stress. This experiment was carried out as a factorial design based on CRD to study the effect of mycorrhiza density (0, 1,000 spores and 2,000 spores) on cucumber (Cucumis sativus cv. Super N3) under low (15°C), high (35°C), and optimum (25°C) temperature root zones. The result showed that low and high root zone temperatures decreased shoot and root fresh weight, chlorophyll content, and antioxidant activity compared to optimum temperature, while the phenols of shoot and NR activity increased in low and high temperature, respectively, as compared to optimum temperature. Both mycorrhiza inoculation (1,000 and 2,000 spores) increased shoot and root fresh weight while mycorrhiza with 1,000 spores increased antioxidant activity and phenol content and NR activity had no influence by mycorrhiza symbiosis. Mycorrhiza inoculation increased SPAD value at optimum temperature. FV/FM reduced by mycorrhiza with 2,000 spores at low and high temperature stress. Total phenol content increased at all temperature levels by mycorrhiza inoculation. Mycorrhiza with 1,000 spore increased antioxidant activity of leaves at all root zone temperatures. NR activity increased with both mycorrhiza inoculation at optimum temperature and decreased at high root zone temperatures. In general, our results showed that mycorrhiza symbiosis had a desirable effect on cucumber culture at low and high root zone temperatures.

      • KCI등재

        Gastric cancer and mesenchymal stem cell-derived exosomes: from pro-tumorigenic effects to anti-cancer vehicles

        Maryam Dolatshahi,Ahmad Reza Bahrami,Qaiser Iftikhar Sheikh,Mohsen Ghanbari,Maryam M. Matin 대한약학회 2024 Archives of Pharmacal Research Vol.47 No.1

        Gastric cancer (GC) is one of the most prevalent malignancies in the world, with a high mortality rate in both womenand men. Conventional treatments, like chemotherapy, radiotherapy and surgery, are facing some drawbacks like acquireddrug resistance and various side eff ects, leading to cancer recurrence and increased morbidity; thus, development of novelapproaches in targeted therapy would be very benefi cial. Exosomes, extracellular vesicles with a size distribution of sub-150 nm, interplay in physiological and pathophysiological cell–cell communications and can pave the way for targeted cancertherapy. Accumulating pieces of evidence have indicated that exosomes derived from mesenchymal stem cells (MSC-EXs)can act as a double-edged sword in some cancers. The purpose of this review is to assess the diff erences between stem celltherapy and exosome therapy. Moreover, our aim is to demonstrate how naïve MSCs transform into GC-MSCs in the tumormicroenvironment. Additionally, the tumorigenic and anti-proliferation eff ects of MSC-EXs derived from diff erent originswere investigated. Finally, we suggest potential modifi cations and combination options that involve utilizing MSC-EXs fromthe foreskin and umbilical cord as promising sources to enhance the effi cacy of gastric cancer treatment. This approach ispresented in contrast to bone marrow cells, which are more heterogeneous, age-related, and are also easily aff ected by thepatient's circulation system.

      • KCI우수등재

        The Effects of Hydro-Alcoholic Extract of Fenugreek Seeds on the Lipid Profile and Oxidative Stress in Fructose-Fed Rats

        Maryam Mohammad-Sadeghipour,Mehdi Afsharinasab,Maryam Mohamadi,Mehdi Mahmoodi,Soudeh Khanamani Falahati-pour,Mohammad Reza Hajizadeh 대한비만학회 2020 The Korean journal of obesity Vol.29 No.3

        Background: Metabolic syndrome (MetS) is a complex clinical disorder that can lead to an increase in oxidative stress. Patients with this syndrome are at risk of diabetes and cardiovascular disease. The Trigonella foenum-graecum L. (fenugreek) plant has many therapeutic effects, including anti-diabetic and antioxidant. The present study aimed to investigate the effects of the hydro-alcoholic extract of fenugreek seeds (HEFS) on dyslipidemia and oxidative stress due to high-fructose diet-induced MetS. Methods: In this experimental study, to induce MetS, animals received water containing 20% fructose for 8 weeks. After induction of MetS, 48 male Wistar rats (200–250 g) were randomized into six groups. HEFS was administered to animals at doses of 100 and 200 mg/kg orally for 4 weeks. Animal blood samples were collected to measure biochemical and antioxidant parameters of fasting plasma glucose (FPG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), malondialdehyde (MDA), glutathione peroxidase (GPX), catalase (CAT), and total antioxidant capacity (TAC). Results: The findings showed that the serum levels of FPG, TC, LDL-C, TG, and MDA were significantly reduced in HEFS-exposed groups compared with the control group (P<0.05). Also, significant increases in HDL-C, GPX, CAT, and TAC levels (P<0.05) were observed. Conclusion: Our results revealed that treatment with HEFS increases the levels of antioxidant enzymes, decreases FPG level, and at the same time, modifies the lipid profile in MetS. Therefore, HEFS may help to alleviate the risk of some chronic complications of this disease.

      • KCI등재

        Biochemical and Rheological Characterization of a Protease from Fruits of Withania coagulans with a Milk-clotting Activity

        Maryam Beigomi,Mohammad Amin Mohammadifar,Maryam Hashemi,Mohsen Ghods rohani,Kalaiselvi Senthil,Mohharam Valizadeh 한국식품과학회 2014 Food Science and Biotechnology Vol.23 No.6

        A protease from Withania coagulans fruits wasevaluated for milk-clotting properties. The optimumtemperature and pH for enzyme activity were 70oC and 4,respectively. The protease also exhibited an excellentthermal stability at 60oC for 30 min. Fractional precipitationusing ammonium sulfate showed that the 40-50% fraction(F5) possessed the highest milk-clotting activity. The F5fraction showed a Mw band of 66 kDa by SDS-PAGE. Gelformation was monitored using low amplitude oscillatoryrheology at different temperatures. An Arrhenius plot wasused to describe the temperature dependence of thegelation rate parameter. Time sweep testing showed that anincrease in temperature was accompanied by a decrease inthe gelation onset time, a higher gel formation rate, andhigher values for final gel strength. W.coagulans fruitshave potential for use as a rennet substitute.

      • KCI등재

        Mn-doped ZnS synthesis in DABCO based ionic liquid: Morphology and electrochemical sensing performance for isoprenaline analysis

        Maryam Sabbaghan,Masoumeh Ghalkhani,Mahshid Hosseini,Maryam Ghanbari 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.95 No.-

        ZnS nanostructures with Mn2+ doping (5%) have been prepared in ionic liquid (IL) through the refluxmethod. The undoped ZnS and Mn2+ doped ZnS (Mn.ZnS) nanostructures produced in the presence andlack of IL, were analyzed using X-ray diffraction, scanning electron microscopy, and Brunauer–Emmett–Teller methods. Then, the surface of the glassy carbon electrode (GCE) was modified by synthesized nanoZnS and Mn.ZnS and electro-activated by successive cyclic voltammetry (CV) in a NaOH solution. Thesensing ability of the modified GCEs towards isoprenaline (ISP) was examined by CV and differentialpulsed voltammetry (DPV) for which less over potentials with sharper redox currents were resultedcompared to the bare GCE. The optimized Mn.ZnS/GCE was stable in buffer solutions in the pH range of 2–8 and exhibited a linear response for ISP concentrations in the range of 0.5–30 mM with promisingsensitivity of 2.1 mA/mM and low detection limit of 90 nM. Adequate selectivity for determining ISP in thepresence of other biological compounds such as ascorbic acid, uric acid at pH 5.0 confirmed the potentialapplicability of Mn.ZnS/GCE for ISP sensing in real biological samples. Finally, an electrochemicalmechanism for the catalytic oxidation of ISP was proposed.

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