Online Filtering of Massive Log Data in the Cloud Computing System

Li Zhou,Baojin Zhu,Xiaopeng Zheng,Liye Zhang 보안공학연구지원센터 2014 International Journal of Database Theory and Appli Vol.7 No.4

Preparation of self‑supporting Co3S4/ S‑rGO film catalyst for efficient oxygen evolution reaction

Liang Chen,Liying Hu,Chenxi Xu,Lanyun Yang,Wei Wang,Junlin Huang,Minjie Zhou,Zhaohui Hou 한국탄소학회 2023 Carbon Letters Vol.33 No.7

Exploring cheap and efficient oxygen evolution reaction (OER) catalysts is extremely vital for the commercial application of advanced energy storage and conversion systems. Herein, a self-supporting Co3S4/ S-doped reduced graphene oxide ( Co3S4/S-rGO) film catalyst is successfully prepared by a blade coating coupled with high-temperature annealing strategy, and its morphology, structure and composition are measured and analyzed. It is substantiated that the as-synthesized Co3S4/ S-rGO film possesses unique self-supporting structure, and is composed of uniformly dispersed Co3S4 nanoparticles and highly conductive S-rGO, which benefit the exposure of catalytic sites and electron transfer. By reason of the synergistic effect of the two individual components, the self-supporting Co3S4/ S-rGO film catalyst displays outstanding catalytic performance towards OER. As a consequence, the Co3S4/ S-rGO film catalyst delivers an overpotential of 341 mV at 10 mA cm-2, and the current attenuation rate is only 2.6% after continuous operation for 4 h, verifying excellent catalytic activity and durability. Clearly, our results offers a good example for the construction of high-performance self-supporting carbon-based composite film catalysts for critical electrocatalytic reactions.

Meta-Analysis of the Efficacy and Safety of Imidafenacin for Overactive Bladder Induced by Benign Prostatic Hyperplasia in Men Receiving Alpha-Blocker Therapy

Tong Cai,Ning Wang,Liye Liang,Zhongbao Zhou,Yong Zhang,Yuanshan Cui 대한배뇨장애요실금학회 2020 International Neurourology Journal Vol.24 No.4

Purpose: The aim of this meta-analysis was to evaluate the efficacy and safety of imidafenacin for overactive bladder (OAB) induced by benign prostatic hyperplasia (BPH) in men receiving alpha-blocker monotherapy.Methods: We performed a systematic research of the PubMed, Embase, and Cochrane Library databases, and searched for studies about alpha-blocker with or without imidafenacin treatment for OAB in patients with BPH. We also investigated the original references of the included texts.Results: Four randomized controlled trials including 779 participants with BPH (389 in the alpha-blocker+imidafenacin group and 390 in the alpha-blocker only group) were studied. The main efficacy endpoint was the Overactive Bladder Symptom Score, which showed a mean difference of -1.88 (95% confidence interval, -2.32 to -1.44; P<0.00001), suggesting that alpha-blocker and imidafenacin treatment was effective in treating men with OAB. As other primary efficacy end points, the International Prostate Symptom Score (IPSS) total score (P=0.47), the IPSS storage symptom score (P=0.07), the IPSS voiding symptom score (P=0.60), and the IPSS quality of life score (P=0.18) indicated that 2 methods had no significant differences in treating men with OAB. In terms of safety, which was assessed using postvoid residual volume (P=0.05) and maximum flow rate (P=0.53), the analysis suggested that combination treatment was very well tolerated.Conclusions: This study suggested that imidafenacin plus alpha-blocker was an efficacious and safe treatment for OAB symptoms in BPH patients.

Detection of Listeria monocytogenes in CSF from Three Patients with Meningoencephalitis by Next-Generation Sequencing

Ming Yao,Jiali Zhou,Yicheng Zhu,Yinxin Zhang,Xia Lv,Ruixue Sun,Ao Shen,Haitao Ren,Liying Cui,Hongzhi Guan,Honglong Wu 대한신경과학회 2016 Journal of Clinical Neurology Vol.12 No.4

Background and Purpose Encephalitis caused by Listeria monocytogenes (L. monocyto¬genes) is rare but sometimes fatal. Early diagnosis is difficult using routine cerebrospinal flu¬id (CSF) tests, while next-generation sequencing (NGS) is increasingly being used for the detection and characterization of pathogens. Methods This study set up and applied unbiased NGS to detect L. monocytogenes in CSF collected from three cases of clinically suspected listeria meningoencephalitis. Results Three cases of patients with acute/subacute meningoencephalitis are reported. Magnetic resonance imaging and blood cultures led to a suspected diagnosis of L. monocy¬togenes, while the CSF cultures were negative. Unbiased NGS of CSF identified and se¬quenced reads corresponding to L. monocytogenes in all three cases. Conclusions This is the first report highlighting the feasibility of applying NGS of CSF as a diagnostic method for central nervous system (CNS) L. monocytogenes infection. Routine application of this technology in clinical microbiology will significantly improve diagnostic methods for CNS infectious diseases.

Sleep deprivation disrupts the lacrimal system and induces dry eye disease

Sanming Li,Ke Ning,Jing Zhou,Yuli Guo,Houjian Zhang,Yu Zhu,Liying Zhang,Changkai Jia,Yongxiong Chen,Peter Sol Reinach,Zuguo Liu,Wei Li 생화학분자생물학회 2018 Experimental and molecular medicine Vol.50 No.-

Sleep deficiency is a common public health problem associated with many diseases, such as obesity and cardiovascular disease. In this study, we established a sleep deprivation (SD) mouse model using a ‘stick over water’ method and observed the effect of sleep deficiency on ocular surface health. We found that SD decreased aqueous tear secretion; increased corneal epithelial cell defects, corneal sensitivity, and apoptosis; and induced squamous metaplasia of the corneal epithelium. These pathological changes mimic the typical features of dry eye. However, there was no obvious corneal inflammation and conjunctival goblet cell change after SD for 10 days. Meanwhile, lacrimal gland hypertrophy along with abnormal lipid metabolites, secretory proteins and free amino-acid profiles became apparent as the SD duration increased. Furthermore, the ocular surface changes induced by SD for 10 days were largely reversed after 14 days of rest. We conclude that SD compromises lacrimal system function and induces dry eye. These findings will benefit the clinical diagnosis and treatment of sleep-disorder-related ocular surface diseases.

Experimental Investigation on Fatigue Strength of Joints between SRC Beams and Concrete-Filled RHS Columns

Qingjun Xian,Le-Wei Tong,Liying Zhou,Yiyi Chen 대한토목학회 2017 KSCE JOURNAL OF CIVIL ENGINEERING Vol.21 No.5

Fatigue behavior, failure mechanism and fatigue strength of joints between steel reinforced concrete (SRC) beams and Concrete Filled Rectangular Hollow Section (CFRHS) columns is discussed in this paper. Three identical beam-to-column joint specimens were designed and tested under static loading and two stages of fatigue loading. In the first stage of fatigue loading, the specimens were subjected to design fatigue load for 2 million cycles, while during the second stage, they were loaded to failure under increased fatigue load in order to know failure mechanism and fatigue strength. It is found that the joints satisfied design requirements when subjected to static loading and design fatigue loading. Fatigue failure occurred after these joints were applied higher-level fatigue loading. The crack initiated at the weld toe of stud or stirrup hole in the upper flange of I-shaped steel in certain SRC beam, and then it propagated along flange width in winding trajectory until fatigue fracture occurred. Stress amplitude of tension flange in SRC beam can be regarded as the parameter representing fatigue strength of the joints. S-N curves in related codes are selected to evaluate fatigue strength of the joints. The design method is suggested to consider fatigue design of the joints.

Experimental Investigation on Fatigue Behavior of Steel Reinforced Concrete Composite Beam-to-Girder Joints

Le-Wei Tong,Qingjun Xian,Liying Zhou,Yiyi Chen,Yunfeng Zhang 한국강구조학회 2012 International Journal of Steel Structures Vol.12 No.4

Fatigue behavior and failure mechanism of steel reinforced concrete (SRC) beam-to-girder joints is discussed in this paper,which is intended for use in high-speed railway station structures due to their high stiffness and load capacity. Three identical SRC beam-to-girder joint specimens were designed and tested under static loading and two stages of fatigue loading. In the first stage of fatigue loading, the specimens were subjected to design fatigue load for 2 million cycles, while during the second stage, the specimens were loaded to failure under increased fatigue loading amplitude in order to know its fatigue strength and failure mechanism. The constructional details of SRC beam-to-girder joint specimen and the method of loading and testing are presented. The comparison in structural behavior of the joint is made between under static and fatigue loading. Fatigue failure characteristics of the joint are described in detail. It is found that the SRC beam-to-girder joints remained in their elastic range and the concrete surface crack did not exceed 0.1 mm when subjected to design static loading and 2 million cycles of design fatigue loading. There was no significant difference in structural behavior of each component of SRC composite beam between static and fatigue loading. Fatigue failure occurred after these joints were applied higher-level fatigue loading for another 0.70to 0.91 million cycles. Fatigue crack was initiated at the tension flange of I-shape steel of beam connected by welding to the flange of I-shape steel of girder or at the hole in tension flange of I-shape steel of beam, and then the crack propagated along flange width and web height of the I-shape steel in beam until the I-shape steel lost loading capacity due to lack of enough cross section. The fatigue behavior of constructional detail of the I-shape steel played a key role in the fatigue strength of the SRC beam-to-girder joints. Discussions on improving the fatigue strength of SRC beam-to-girder joints and future research aspects are presented finally.