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      • Spatio-Temporal Consistency Enhancement for Disparity Sequence

        Haixu Liu,Chenyu Liu,Yufang Tang,Haohui Sun,Xueming Li 보안공학연구지원센터 2014 International Journal of Signal Processing, Image Vol.7 No.5

        Disparity estimation for still images has attracted much interest and acquired many promising results. However, simply applying these methods to produce a disparity sequence may suffer from the undesirable flickering artifacts. These errors not only distinctly decrease the visible quality of the synthesized video, but also significantly reduce the coding efficiency of the disparity sequence. In this paper, a novel temporal consistency enhancement algorithm based on Guided Filter and Temporal Gradient (GFTG) is proposed. The flickering artifacts and noises are effectively removed and the edges of objects are well preserved. Both quantitative and qualitative evaluations show that the spatio-temporal consistency has been highly improved by utilizing our approach.

      • KCI등재

        The CREG1-FBXO27-LAMP2 axis alleviates diabetic cardiomyopathy by promoting autophagy in cardiomyocytes

        Liu Dan,Xing Ruinan,Zhang Quanyu,Tian Xiaoxiang,Qi Yanping,Song Haixu,Liu Yanxia,Yu Haibo,Zhang Xiaolin,Jing Quanmin,Yan Chenghui,Han Yaling 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-

        Autophagy plays an important role in the development of diabetic cardiomyopathy. Cellular repressor of E1A-stimulated genes 1 (CREG1) is an important myocardial protective factor. The aim of this study was to investigate the effects and mechanisms of CREG1 in diabetic cardiomyopathy. Male C57BL/6 J mice, Creg1 transgenic mice and cardiac-specific knockout mice were used to establish a type 2 diabetes model. Small animal ultrasound, Masson’s staining and western blotting were used to evaluate cardiac function, myocardial fibrosis and autophagy. Neonatal mouse cardiomyocytes (NMCMs) were stimulated with palmitate, and the effects of CREG1 on NMCMs autophagy were examined. CREG1 deficiency exacerbated cardiac dysfunction, cardiac hypertrophy and fibrosis in mice with diabetic cardiomyopathy, which was accompanied by exacerbated autophagy dysfunction. CREG1 overexpression improved cardiac function and ameliorated cardiac hypertrophy and fibrosis in diabetic cardiomyopathy by improving autophagy. CREG1 protein expression was decreased in palmitate-induced NMCMs. CREG1 knockdown exacerbated cardiomyocyte hypertrophy and inhibited autophagy. CREG1 overexpression inhibited cardiomyocyte hypertrophy and improved autophagy. LAMP2 overexpression reversed the effect of CREG1 knockdown on palmitate-induced inhibition of cardiomyocyte autophagy. CREG1 inhibited LAMP2 protein degradation by inhibiting the protein expression of F-box protein 27 (FBXO27). Our findings indicate new roles of CREG1 in the development of diabetic cardiomyopathy.

      • KCI등재

        Fatigue life prediction and reliability analysis of the forage crusher rotor

        Haixu Zhao,Zhiping Zhai,Yingsheng Mou,Le Liu,Yuezheng Lan,Hongmei Cui 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.4

        To accurately predict fatigue life and reliability of the forage crusher rotor, the stress load spectrum of the rotor is obtained via the two-way fluid-structure coupling method, which calculates the coupled flow field in the forage crusher and rotor structure. The fatigue life of the rotor is predicted, and its reliability is analyzed. Finally, the rotor is optimized by a multiisland genetic algorithm. The results indicate that the fatigue life prediction based on fracture mechanics theory and the Gerber average stress correction method is more suitable for the prediction of the rotor’s fatigue life. After optimization, the fatigue life cycles of the rotor are increased from 1.229×10 8 to 7.67×10 8 and the reliability is increased from 89.4 % to 99.7 %. This meets the reliability requirement of key parts of agricultural and animal husbandry machinery. This study provides a reference for the prediction and optimization of fatigue life and reliability of forage crushers.

      • KCI등재

        Effect of Co Doping on the Elastocaloric Effect of Ni-Mn-Ga-Co Alloy

        Haixu Qin,Youping Zheng,Liu Yang,Sibo Sun,Zhiyong Gao 한국자기학회 2023 Journal of Magnetics Vol.28 No.3

        Large latent heat is produced in the stress-induced martensitic phase transition process of Ni-Mn-Ca-based materials, i.e., elastocaloric effect. That makes such materials show tremendous potential for solid-state refrigeration which is identified as one of the most promising non-vapor-compression cooling devices. However, the still low refrigeration ability of these materials restricts further commercially promoting of solid-state refrigeration. In this work, we adjusted the Co content to regulate the elastocaloric effect for the Ni51.5Mn25Ga23Co0.5. According to the results, the transformation strain and ratio of loading stress/transformation temperature (dσ/ dT) were increased by replacing the Ni atoms with a little more Co, leading to an improvement of the stressinduced transformation entropy-change ΔSσ. As a result, a huge ΔSσ of 45.0 JKg-1K-1 is achieved in Ni50Mn25- Ga23Co1 alloy.

      • KCI등재

        Study on Oxidant in Chemical Mechanical Polishing of Copper

        Xu Rui,Wang Yongsheng,Wang Yipu,Liu Haixu,Su Jianxiu 한국전기전자재료학회 2020 Transactions on Electrical and Electronic Material Vol.21 No.6

        In this paper, the polishing experiment of copper was carried out. According to the experimental data, when FeCl 3 was selected as oxidant, the material removal rate increases gradually with the increase of oxidant concentration. When other conditions remain unchanged, the material removal rate with larger abrasives was higher than that of smaller abrasives, and the material removal rate of pressure 3 psi was higher than that of pressure 2 psi, and the surface roughness became smaller and smaller. When the abrasive size was 1 μm, oxidant concentration was 5 g/L and the pressure was 3 psi, the material removal rate reaches 206.9 nm/min and the surface roughness reached 8 nm. When the type of oxidant was chosen as the variable, the material removal rate of the mixture of FeCl 3 and H 2 O 2 was the highest, the maximum removal rate was 105.45 nm/min when the abrasive size was 1 μm and polishing speed was 80 r/min. The surface roughness was the smallest when FeCl 3 was used as oxidant and Ra reaches the smallest 5 nm under the conditions of the abrasive size was 1 μm and polishing speed 80 r/min. The results can be used as a reference for further research the ingredients of polishing slurry in the chemical mechanical polishing of copper.

      • KCI등재

        Hydrogenation of ethyl acetate to ethanol over Cu/ZnO/MOx (MOx = SiO2, Al2O3, and ZrO2) catalysts

        Zhipeng Lu,Hengbo Yin,Aili Wang,Jing Hu,Wuping Xue,Haixu Yin,Shuxin Liu 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.37 No.-

        The Cu/ZnO/SiO2, Cu/ZnO/Al2O3, and Cu/ZnO/ZrO2 catalysts prepared by the co-precipitation methodwere used for the catalytic hydrogenation of ethyl acetate to ethanol. The addition of ZnO in the Cu/ZnO/MOx catalysts improved their catalytic activities for the hydrogenation reaction. Small-sized coppercrystallite and high surface acidity favored the catalytic hydrogenation of ethyl acetate to ethanol. TheCu/ZnO/Al2O3 catalyst gave the ethanol selectivity of ca. 95% at the ethyl acetate conversion of ca. 80%when the reaction temperature was 280 8C. The reaction activation energy over Cu/ZnO/Al2O3 catalystwas 115 kJ mol 1, lower than those over the Cu/ZnO/SiO2 and Cu/ZnO/ZrO2 catalysts.

      • KCI등재

        Establishment and evaluation of a murine anb3-integrinexpressing cell line with increased susceptibility to Foot-and-mouth disease virus

        Wei Zhang,Kaiqi Lian,Fan Yang,Yang Yang,Zhijian Zhu,Zixiang Zhu,Weijun Cao,Ruoqing Mao,Ye Jin,Jijun He,Jianhong Guo,Xiangtao Liu,Haixue Zheng 대한수의학회 2015 Journal of Veterinary Science Vol.16 No.3

        Integrin anb3 plays a major role in various signaling pathways, cell apoptosis, and tumor angiogenesis. To examine the functions and rolesof anb3 integrin, a stable CHO-677 cell line expressing the murine anb3 heterodimer (designated as “CHO-677-manb3” cells) wasestablished using a highly efficient lentiviral-mediated gene transfer technique. Integrin subunits an and b3 were detected at the gene andprotein levels by polymerase chain reaction (PCR) and indirect immunofluorescent assay (IFA), respectively, in the CHO-677-manb3 cellline at the 20th passage, implying that these genes were successfully introduced into the CHO-677 cells and expressed stably. A plaque-formingassay, 50% tissue culture infective dose (TCID50), real-time quantitative reverse transcription-PCR, and IFA were used to detect the replicationlevels of Foot-and-mouth disease virus (FMDV) in the CHO-677-manb3 cell line. After infection with FMDV/O/ZK/93, the cell line showeda significant increase in viral RNA and protein compared with CHO-677 cells. These findings suggest that we successfully established a stableanb3-receptor-expressing cell line with increased susceptibility to FMDV. This cell line will be very useful for further investigation of anb3integrin, and as a cell model for FMDV research.

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