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RISS 인기검색어
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- 저자 : Lee Song-Shil (검색결과 43 건)
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서병관,류성룡,이송실,허정은,백용현,이재동,최도영,조윤제,김남재,박동석 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-
Objective : The aim of this study was to review systemically clinical trials on the effectiveness and safety of herbal medicines in the treatment of osteoarthritis. Methods : Computerized literature searches were carried out on seven electronic databases, and hand-searching on some chinese medical journals in library of Kyung Hee Medical Center. Trial data were extracted in a standardized, predefined manner and assessed independently. Results : 1. Thirty reports of clinical trials and two reports of meta-analyses concerning herbal medicine were collected and reviewed Among these reports three medical herbs were applied as topical medicine and others as internal medicine. 2. The western studies established NSAIDs or placebo as their control group. Five chinese reports established formulated herb pill(Ruanshnagshenjin pill) as their control group and Six did not establish a control group at all. 3. ACR was the most highly used diagnostic criteria in the western studies while the Chinese used their official criteria established by their government or the criteria of their text books. 4. 20 reports chose the Lequesne functional index, SHAQ, WOMAC OA index, AIMS, and their own unique scoring system as the criteria of analysing the effect. Others chose clinical symptoms, articular functions, and lab finding as their criteria. 5. 7 single herbs and 19 formulated herbs were studied. Among the formulated herbs, Achyranthes japonica was studied in 10 of the studies and Angelica gigantis Radix in 8, making them the most often studied herbs among the studies.
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An experimental study on the effect of Omahwan administration in aged human immune system
Lee, Sang-Jae,Lee, Song-Shil,Kim, Kwang-Ho INSTITUTE OF ORIENTAL MEDICINE KYUNG-HEE UNIVERSIT 2000 JOURNAL OF ORIENTAL MEDICINE Vol.5 No.1
To examine effect of omahwan(烏麻丸)-赤何首烏(Polygonum multiflorum THUNB.) 白何首烏(Cynanchum wilfordii H.) 黑芝麻(Sesamum indicum L.)-on the aged human immune system, a series of humoral immunological parameters was compared in aged femal (age 60-70 years) before and after administration of omahwan(烏麻丸). Peripheral blood was obtained from fifteen healthy young (age 20-29, mean=66.3) female volunteers. B cell, T cell(T cells, T helper, and T suppressor/cytotoxic) subsets was examined with specific monoclonal antibodies and isotype controls, using dural color flow cytometer. IL-2 was examined with ELISA kit By comparing the immune characteristics of the yonger and elder groups the total ratio of T-cell, CD8 T-cell and quantity of IL-2 was significantly lower while CD4/CD8 ratio was considerably greater in the elder group. (p<0.05, student t-test) After giving Omahwan fro 30 days to the elder group, by comparing the ratio before and after prescription the total T cell and CD8 T cell ratio was considerably greater after prescription. (p<0.05, paried t-test) The quantity of IL-2 tended to increase after prescription but has no statistical meaning. The results indicate that administration of Omahwan(烏麻丸) differentially affects various aspects of the immune system in aged human.
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Transplantation of Bone Marrow-Derived Mesenchymal Stem Cells into the Developing Mouse Eye
Lee, Eun-Shil,Yu, Song-Hee,Jang, Yu-Jin,Hwang, Dong-Youn,Jeon, Chang-Jin Japan Society of Histochemistry and Cytochemistry 2011 Acta histochemica et cytochemica Vol.44 No.5
<P>Mesenchymal stem cells (MSCs) have been studied widely for their potential to differentiate into various lineage cells including neural cells <I>in vitro</I> and <I>in vivo</I>. To investigate the influence of the developing host environment on the integration and morphological and molecular differentiation of MSCs, human bone marrow-derived mesenchymal stem cells (BM-MSCs) were transplanted into the developing mouse retina. Enhanced green fluorescent protein (GFP)-expressing BM-MSCs were transplanted by intraocular injections into mice, ranging in ages from 1 day postnatal (PN) to 10 days PN. The survival dates ranged from 7 days post-transplantation (DPT) to 28DPT, at which time an immunohistochemical analysis was performed on the eyes. The transplanted BM-MSCs survived and showed morphological differentiation into neural cells and some processes within the host retina. Some transplanted cells expressed microtubule associated protein 2 (MAP2ab, marker for mature neural cells) or glial fibrillary acid protein (GFAP, marker for glial cells) at 5PN 7DPT. In addition, some transplanted cells integrated into the developing retina. The morphological and molecular differentiation and integration within the 5PN 7DPT eye was greater than those of other-aged host eye. The present findings suggest that the age of the host environment can strongly influence the differentiation and integration of BM-MSCs.</P>
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Transplantation of Adipose Derived Stromal Cells into the Developing Mouse Eye
Yu, Song-Hee,Jang, Yu-Jin,Lee, Eun-Shil,Hwang, Dong-Youn,Jeon, Chang-Jin Japan Society of Histochemistry and Cytochemistry 2010 Acta histochemica et cytochemica Vol.43 No.6
<P>Adipose derived stromal cells (ADSCs) were transplanted into a developing mouse eye to investigate the influence of a developing host micro environment on integration and differentiation. Green fluorescent protein-expressing ADSCs were transplanted by intraocular injections. The age of the mouse was in the range of 1 to 10 days postnatal (PN). Survival dates ranged from 7 to 28 post transplantation (DPT), at which time immunohistochemistry was performed. The transplanted ADSCs displayed some morphological differentiations in the host eye. Some cells expressed microtubule associated protein 2 (marker for mature neuron), or glial fibrillary acid protein (marker for glial cell). In addition, some cells integrated into the ganglion cell layer. The integration and differentiation of the transplanted ADSCs in the 5 and 10 PN 7 DPT were better than in the host eye the other age ranges. This study was aimed at demonstrating how the age of host micro environment would influence the differentiation and integration of the transplanted ADSCs. However, it was found that the integration and differentiation into the developing retina were very limited when compared with other stem cells, such as murine brain progenitor cell.</P>
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Air Data Module 적용을 위한 고정밀 MEMS 차압센서 개발
유은실(Eun-Shil Yoo),이장섭(Jang-Sub Lee),안준은(Jun-Eon An),박치현(Chi-Hyun Park),송진우(Jin-Woo Song) 제어로봇시스템학회 2012 제어로봇시스템학회 합동학술대회 논문집 Vol.2012 No.7
I비행체의 이동속도를 측정하는 차압센서는 Air Data Module의 핵심부품으로 높은 정밀도가 요구되며 해외에서 수입되고 있다. 이로 인해 많은 시간과 비용이 지출되고 핵심부품을 해외에 의존하게 되므로 국산화된 차압센서 개발이 필요하다. 따라서 본 연구에서는 국산화를 위해 MEMS 고정밀 차압센서를 설계 및 제작하였다. 센서는 SOI 웨이퍼와 고횡비 실리콘 식각 기술을 이용하여 박막 두께와 크기를 정밀하게 제어하였다. 압력에 의해 발생된 박막의 응력은 이온주입으로 형성된 압저항의 저항값 변화로 나타나며, 이러한 압저항은 온도의 영향을 최소화하기 위하여 휘스톤 브릿지 형태로 구성하였다. 제작된 센서는 압력이 누설되지 않도록 설계 및 제작된 고신뢰 패키지에 조립되었다. 개발된 센서는 최대 차압 20psi(137.9㎪)까지 측정 가능하며, 비선형성 0.1%FSO 이하, 반복성 0.05%FSO 이하, 히스테리시스 0.1%FSO 이하의 성능을 가진다. 이는 현재 도입되고 있는 해외 부품의 성능과 유사한 정밀도로 Air Data Module용 차압센서의 수입대체뿐만 아니라 특수 산업용 분야까지 적용 가능할 것으로 기대된다.
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마늘(Allium sativum)의 프로스타글란딘과 에탄올 추출물이 흰쥐의 혈청 성분에 미치는 영향
김송전(Kim Song Chon),이인실(Lee In Shil) 한국유화학회 1992 한국응용과학기술학회지 Vol.9 No.2
This study was separated and identified prostaglandin from garlic by TLC, HPLC, and Gc-Mass. In this experiment aimed at researching the effects of garic on body weight, and serum lipid, protein and glucose in male rats. The male rats applied in this work were 42 of Sprague-Dawley strain. In addition to basal diet, the worker administrated 4 groups of the experimental rats solutions which were 0.2 and 0.4ml of raw garlic juice, and of etanol garlic extract with together 2.5% cholesterol solution solved by corn oil for 8 weeks respectively. These results were as follows. 1. Separated and identified of Prostaglandin from garlic. 2. The growth rate of body weight and food efficiency ratio(FER) appeared to be more increased in the experimental groups administrated ethanol garlic extract than raw garlic juice. 3. The content of serum total cholesterol apperaded to be decreased in the experimental group administrated 0.4ml of ethanol garlic extract. 4. The level of serum HDL-cholesterol had a tendency to be more increased in all the experimental groups administrated garlic than control group. 5. The level of serum glucose appeared to be decreased in all the experimental groups administrated garlic, particularly ethanol garlic extract.
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Development of a Piezoresistive MEMS Pressure Sensor for a Precision Air Data Module
Jang-Sub Lee,Eun-Shil Yoo,Chi-Hyun Park,Jun-Eon An,Chan Gook Park,Jin Woo Song 제어로봇시스템학회 2014 제어로봇시스템학회 국제학술대회 논문집 Vol.2014 No.10
In this paper, the design and fabrication techniques of a differential pressure sensor used in precision air data module (ADM) are described, and its performance test results are presented. A differential pressure senor for an ADM detects the differential pressure between static and total pressure, which can cover differential pressure of 0~20psi range with less than 1% accuracy. In order to satisfy these requirements, the piezoresistive Wheatstone bridge on the silicon diaphragm is used as a strain gauge. The p-type piezoresistors are implanted on the diaphragm under high doping concentration level for achieving smaller temperature sensitivity, and each resistor is designed to have same shape to compensate common errors. A constant current is applied to the bridge, which makes the temperature effects on piezoresistive coefficients and resistors compensate each other. The proposed differential sensor is designed through FEM analysis in order to satisfy nonlinearity requirements for an ADM. The repeatability and nonlinearity of the sensor are less than 0.09% and 0.27%, respectively, and the pressure hysteresis is less than 0.63%, which contributes to the root sum square (RSS) accuracy of 0.69%.
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(Sang Jae Lee),(Song Shil Lee),(Kwang Ho Kim) 경희대학교 한의학연구소 2000 JOURNAL OF ORIENTAL MEDICINE Vol.5 No.1
To examine effect of omahwan(烏麻丸)-赤何首烏(Polygonum multiflorum THUNB.), 白何首烏 (Cynanchum wilfordii H.), 黑芝麻(Sesamum indicum L.)-on the aged human immune system, a series of humoral immunological parameters was compared in aged female (age 60-70 years) before
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