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      • n-터플에 기초한 두 가지 완전 해싱 기법

        이종근,강신준 國立 昌原大學校 基礎科學硏究所 1993 基礎科學硏究所論文集 Vol.4 No.-

        본 논문에서는 n터플을 기초로 한 두 가지 완전 해쉬기법을 제시 하였다. 사실 n터플은 heuristic알고리즘을 이용하여 문자의 집합으로 표시할 수 있으며, 이는 다시 0/1 행렬이나 터플 테이블로 표시 된다. 본 연구에서는 Ziegler기법을 이용하여 완전 해쉬 함수를 구조하였다. In this paper, two new perfect hashing methods based on n-tuple are presented. A unique n-tuple from a set of words extracted by a heuristic algorithm. Then the extracted n-tuples are mapped into a 0/1 sparse matrix or tuple table. Using Ziegler's row displacement method or backtracking a perfect hash function is constructed.

      • Sodium Dodecyl Sulfate의 분해반응에 대한 속도론적 연구

        이길준,김종용,박병각 嶺南大學校 環境問題硏究所 1994 環境硏究 Vol.14 No.1

        하천수에서 분리해 낸 SDS(Sodium Dodecyl Sulfate) 분해균주에 의하여 분해균주량의 변화와 SDS의 농도변화를 주어 SDS를 분해시킬 때 그 분해반응을 속도론적으로 연구하였다. 실험결과 SDS의 분해를 BOD로 표시하여 분해률을 측정한 속도식은 1차로 나타남을 알 수 있었다. 그리고 분해균주량의 변화와 SDS농도의 변화에 따른 속도상수는 분해규준량에는 영향을 받지 않으나 SDS의 농도에는 영향을 받음을 알 수 있었다. 그리고 활성화에너지는 5.304kcal/mol, 활성화 파라메타인 ???와 ???는 각각 4.69kcal/mol, -56.90 e.u.임을 알았다. Kinetic studies were carried out for change in BOD of SDS degradating microorganism isolated from river water. It is found that the decomposition of SDS is first order. Rate constants for the decomposition of SDS and its degrading microorganism found not to have an influence on variation of SDS-degrading microorganism but have an influence on SDS concentration. And thermodynamic parameters, Ea, ???? and ????, were obtained the value of 5.304kcal/mol, 4.69kcal/mol and -56.90 e.u., respectively.

      • KCI등재

        E-초등학교 어린이의 영구치 맹출시기 및 순서

        권정현,최병재,이제호,김성오,손흥규,최형준 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.2

        치아 맹출은 나이, 성별, 인종, 시대에 따라 시기 및 순서의 차이가 있으나, 교과서에 인용되어 임상에서 사용되는 영구치 맹출 및 치근 형성에 대한 자료는 1933년 Logan과 Kronfeld가 발표한 것이므로 현재 한국 어린이의 영구치 맹출 경향과 차이가 있을 수 있다. 따라서 이번 연구의 목적은 한국 어린이의 영구치 맹출연령을 구하고, 이를 근거로 맹출순서를 알아보며, 이전 국내외 연구자료와 비교하여 차이를 알아보는 것이다. 이에 1998년부터 2005년까지 연세대학교 치과대학병원 소아치과에 내원하여 구강검진을 시행한 E-초등학교의 어린이 중 만 6세에서 만 12세의 2,619명 (남자 1,307명, 여자 1,312명)의 자료를 수집하여 영구치의 맹출시기 및 순서에 대해 연구 한 바 다음과 같은 결론을 얻었다. 1. 상악의 영구치 맹출시기는 중절치는 남자 만 6.81세, 여자 만 6.73세, 측절치는 남자 만7.78세, 여자 만7.65세, 견치는 남자 만10.48세, 여자 만9.92세, 제1소구치는 남자 만9.76세, 여자 만9.63세, 제2소구치는 남자 만10.66세, 여자 만10.49세, 제1대구치는 남자 만6.39세, 여자 만6.26세, 제2대구치는 남자 만12.13세, 여자 만 12.03세로 나타났다. 2. 하악의 영구치 맹출시기는 중절치는 남녀 모두 정확한 시기의 측정은 불가능하였지만, 만 6.08세 이전에 맹출한다는 것을 추정 할 수 있었고, 측절치는 남자 만6.78세, 여자 만6.65세, 견치는 남자 만9.76세, 여자 만9.05세, 제1소구치는 남자 만9.82세, 여자 만9.59세, 제2소구치는 남자 만10.67세, 여자 만10.52세, 제1대구치는 남자 만6.22세, 여자 만6.12세, 제2대구치는 남자 만11.58세, 여자 만 11.14세로 나타났다. 3. 맹출순서는 상악은 제1대구치, 중절치, 측절치, 제1소구치, 견치, 제2소구치, 제2대구치 순이었고, 하악은 중절치, 제1대구치, 측절치, 견치, 제1소구치, 제2소구치, 제2대구치 순이었다. 4. 모든 영구치에서 남자보다 여자가 빨리 맹출하였으며, 상악은 약 0.19세, 하악은 약 0.29세 먼저 맹출하였다. 5. 남녀 모두 상악은 측절치와 제1소구치 사이, 하악은 측절치와 견치 사이에 휴지기가 있었고, 남자의 휴지기는 상악 1.98년, 하악 2.98년, 여자는 상악 1.98년, 하악 2.40년이었다. The purpose of this study was to present new data on the timing and sequence of permanent teeth emergence and to compare these findings with the results of earlier studies. The dental examinations had been performed to E-elementary school students, who visited the Yonsei University Dental Hospital between 1998 and 2005; 1,307 boys and 1,312 girls with the age ranging from 6 to 12 years old. The followings were concluded. 1. Eruption time of the maxillary permanent teeth is as follows, It was 6.81 years in male and 6.73 years in female for the central incisor, 7.78 years in male and 7.65 years in female for the lateral incisor, 10.48 years in male and 9.92 years in female for the canine, 9.76 years in male and 9.63 years in female for the first premolar, 10.66 years in male and 10.49 years in female for the second premolar, 6.39 years in male and 6.26 years in female for the first permanent molar, and 12.13 years in male and 12.03 years in female for the second permanent molar. 2. Eruption time of the mandibular permanent teeth is as follows. The central incisor could not be determined in this study, but it is assumed to erupt before the age of 6.08. In the mandible, eruption time was 6.78 years in male and 6.65 years in female for the lateral incisor, 9.76 years in male and 9.05 years in female for the canine, 9.82 years in male and 9.59 years in female for the first premolar, 10.67 years in male and 10.52 years in female for the second premolar, 6.22 years in male and 6.12 years in female for the first permanent molar, and 11.58 years in male and 11.14 years in female for the second permanent molar. 3. The eruption sequence is as follows. In the maxilla, the first permanent molar erupted first, followed by the central incisor, the lateral incisor, the first premolar, the canine, the second premolar, and the second permanent molar. In the mandible, the central incisor erupted first, followed by the first permanent molar, the lateral incisor, the canine, the first premolar, the second premolar, and the second permanent molar. 4. Tooth eruption occurred earlier in female compared to male by average of 0.19 year in the maxilla and 0.29 year in the mandible. 5. In both male and female, the hiatus (interval of rest) occurred between the emergence of lateral incisor and first premolar in the maxilla while it was observed between the lateral incisor and canine in the mandible. Male had a hiatus of 1.98 years in the maxilla and 2.90 years in the mandible, while the female's were 1.98 years and 2.40 years, respectively.

      • 염소이온이 코발트의 부식반응에 미치는 영향

        朱宰伯,李政峻 弘益大學校 科學技術硏究所 2000 科學技術硏究論文集 Vol.11 No.-

        Electrochmical dissolution behavior of cobalt in chloride solution was investigated. Kinetic data of cobalt dissolution and hydrogen reduction were measured in acid and alkaline solutions containing chloride ions at several pH values. Rotating disc electrode was used in order to eliminate the mass transport limitations at the electrode surface. The effect of pH on the corrosion potential and corrosion current were observed. Also the kinetic mechanism of cobalt dissolution in acid solution was examined. It was found that the dissolution behavior in chloride solution is quite different from that in sulfate solution.

      • SCIESCOPUSKCI등재

        The Microencapsulated Ascorbic Acid Release in vitro and Its Effect on Iron Bioavailability

        Lee, Jun-Beum,Ahn, Joung-Jwa,Lee, Jong-Hwi,Kwak, Hae-Soo The Pharmaceutical Society of Korea 2003 Archives of Pharmacal Research Vol.26 No.10

        The present study was carried out to examine the stability of microencapsulated ascorbic acid in simulated-gastric and intestinal situation in vitro and the effect of microencapsulated ascorbic acid on iron bioavailability. Coating materials used were polyglycerol monostearate (PGMS) and medium-chain triacylglycerol (MCT), and core materials were L-ascorbic acid and ferric ammonium sulfate. When ascorbic acid was microencapsulated by MCT, the release of ascorbic acid was 6.3% at pH 5 and 1.32% at pH 2 in simulated-gastric fluids during 60 min. When ascorbic acid was microencapsulated by PGMS, the more ascorbic acid was released in the range of 9.5 to 16.0%. Comparatively, ascorbic acid release increased significantly as 94.7% and 83.8% coated by MCT and PGMS, respectively, for 60 min incubation in simulated-intestinal fluid. In the subsequent study, we tested whether ascorbic acid enhanced the iron bioavailability or not. In results, serum iron content and transferring saturation increased dramatically when subjects consumed milks containing both encapsulated iron and encapsulated ascorbic acid, compared with those when consumed uncapsulated iron or encapsulated iron without ascorbic acid. Therefore, the present data indicated that microencapsulated ascorbic acid with both PGMS and MCT were effective means for fortifying ascorbic acid into milk and for enhancing the iron bioavailability.

      • KCI등재

        Analysis of Uterine Bacteria to Increase Reproductive Efficiency in Hanwoo(Korean Native Cattle)

        Joung-Jun Park,Han-Jun Yoo,Young-Jae Cho,Hye-Won Choi,Pil-Sang Yoon,Seon-Goo Lee,Bae-Dong Jung,Tae-Wook Hahn 韓國受精卵移植學會 2013 한국동물생명공학회지 Vol.28 No.1

        The objective of this study was to evaluate several types of uterine bacteria in Hanwoo. uterine bacteria from randomly selected 5 uterus was collected by flushing methods into a sterilized 1.5 ml centrifuge tube and was inoculated onto MacConkey agar and blood agar, respectively. After being incubated for 5% CO2, aerobic or anaerobic condition at 37℃ during 48h, bacterial colonies were selected and re-inoculated onto blood agar plates. Re-cultured colonies were identified by Gram staining and finally identified using Vitek system. The identified bacteria were Staphylococcus lentus, Staphylococcus sciuri, Staphylococcus vitulinus, Staphylococcus warneri of Gram (+) and Rhizobium radiobacter, Sphingomonas paucimobilis of Gram () bacteria. Although, pathogenicity of identified bacteria was unclear, the bacteria can have an effect on the uterine microenvironment. Therefore, repetitive research will be required to determine the effects of bacteria in cattle exposed to a various environment.

      • Identification of Antiadipogenic Constituents of the Rhizomes of Anemarrhena asphodeloides

        Joung Youn, Ui,Ye Seul, Lee,Ha Na, Jung,Jun, Lee,Joo Won, Nam,Yoo Jin, Lee,Eun Sook, Hwang,Je Hyun, Lee,Dong Ho, Lee,Sam Sik, Kang,Eun Kyoung, Seo 이화여자대학교 약학연구소 2010 藥學硏究論文集 Vol.- No.20

        Three new phenolic compounds, (E)-4'-demethyl-6-methyleucomin (1), anemarcoumarin A (2), and anemarchalconyn (3), were isolated from an ethyl acetate extract of the rhizomes of Anemarrhena asphodeloides, together with seven known compounds (4-10). The structures of the new compounds (1-3) were determined on the basis of spectroscopic data interpretation. Compound 3 exhibited a potent inhibitory effect against the differentiation of preadipocyte 3T3-L1 cells with an IC50 value of 5.3 microM.

      • SCISCIESCOPUS

        Two New Stereoisomers of Neolignan and Lignan from the Flower Buds of <i>Magnolia fargesii</i>

        Lee, Jun,Seo, Eun-Kyoung,Jang, Dae Sik,Ha, Tae Joung,Kim, Jong-Pyung,Nam, Joo-Won,Bae, Green,Lee, Yun Mi,Yang, Min Suk,Kim, Jin Sook The Pharmaceutical Society of Japan 2009 Chemical & pharmaceutical bulletin Vol.57 No.3

        <P>A new stereoisomer of 8-<I>O</I>-4′ system neolignan, (7<I>R</I>,8<I>S</I>)-1-(3,4-dimethoxyphenyl)-2-[4-(3-hydroxy-1-propenyl)-2-methoxyphenoxy]-propane-1,3-diol (1) and a new stereoisomer of tetrahydrofuranoid lignan, (7<I>R</I>,8<I>S</I>,7′<I>S</I>,8′<I>R</I>)-(3,4,5,3′,4′)-pentamethoxy-9,7′-dihydroxy-8.8′,7.<I>O</I>.9′-lignan (2) along with seven known lignans and neolignans (3—9) were isolated from the methanol extracts of the flower buds of <I>Magnolia fargesii</I>. The structures of these compounds (1—9) were elucidated by spectroscopic methods including 1D- and 2D-NMR as well as by comparison with reported values. Absolute configurations of new stereoisomers 1 and 2 were determined by circular dichroism (CD) spectra. The absolute configuration of (7<I>S</I>,8<I>S</I>,10<I>S</I>)-[tetrahydro-4-hydroxy-2-(3,4,5-trimethoxyphenyl)furan-3-yl]methyl 3,4-dimethoxy benzoate (3) was determined by Mosher's esterification method for the first time in this study. Three lignans, tanegool (4), (+)-dehydrodiconiferyl alcohol (5), and epieudes-min (6), were isolated from this plant for the first time. Superoxide radical scavenging activities of the isolates (1—9) were measured by irradiated riboflavin/ethylenediaminetetraacetic acid (EDTA)/Nitroblue tetrazolium (NBT) system, and their <I>in vitro</I> rat lens aldose reductase (RLAR) inhibitory activities were also evaluated.</P>

      • KCI등재
      • The safety and efficacy of vitamin K antagonist in patients with atrial fibrillation and liver cirrhosis

        Lee, Seung-Jun,Uhm, Jae-Sun,Kim, Jong-Youn,Pak, Hui-Nam,Lee, Moon-Hyoung,Joung, Boyoung Elsevier 2015 INTERNATIONAL JOURNAL OF CARDIOLOGY Vol.180 No.-

        <P><B>Abstract</B></P> <P><B>Background</B></P> <P>Bleeding is a major concern in treatment of atrial fibrillation (AF) with vitamin K antagonist (VKA). This concern is more emphasized in patients with high bleeding risk such as liver cirrhosis (LC).</P> <P><B>Methods and results</B></P> <P>We retrospectively analyzed incidence of stroke and major bleeding in 321 AF patients with LC, including early [Child-Pugh (CP)-A, n=215] and advanced [CP-B or C, n=106] LC according to VKA prescription. The CHA<SUB>2</SUB>DS<SUB>2</SUB>-VASc, HAS-BLED and MELD scores were higher in patients with VKA. CP score was positively correlated with HAS-BLED score (rho: 0.602). The incidence of major bleeding was higher in advanced LC than in early LC (14.5%/year vs. 4.9%/year, p<0.001). VKA reduced the risk of ischemic stroke in AF patients with LC, whereas it significantly increased the major bleeding risk. There was no difference in survival free from significant clinical events (SCEs) between the patients with or without VKA (p=0.91). On subgroup analysis, VKA was beneficial in early LC patients, as it decreased stroke without increasing major bleeding risk. However, in advanced LC patients, VKA significantly increased the risk of major bleeding, especially variceal origin, that overwhelms stroke reduction. As a result, VKA treatment reduced the risk of SCEs in early LC patients, whereas it increased the risk of SCEs in advanced LC.</P> <P><B>Conclusions</B></P> <P>VKA treatment might be beneficial to reduce significant clinical events in the early LC but not in the advanced LC group. However to confirm this hypothesis, a prospective randomized study is needed.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We evaluated the safety and efficacy of VKA in AF patients with liver cirrhosis. </LI> <LI> VKA did not show net clinical benefit in these patients as the increased bleeding risk offsetted the stroke reduction. </LI> <LI> However, in Child-Pugh class A patients, VKA reduced ischemic stroke without increasing bleeding which resulted in favorable net clinical benefit. </LI> <LI> On the contrary, VKA treatment was shown to be harmful in advanced LC patients, as the variceal bleeding risk significantly increased overwhelmed the beneficial effect. </LI> </UL> </P>

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