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      • 영화 시청 시 자폐스펙트럼 장애 환자가 보이는 비전형적 뇌신호 기능적 경향성의 동적 패턴 분석

        이종은(Jong-eun Lee),박현진(Hyunjin Park) 한국정보통신학회 2023 한국정보통신학회 종합학술대회 논문집 Vol.27 No.1

        자폐 스펙트럼 장애(Autism Spectrum Disorder, ASD)는 외부 세계를 다르게 지각하는 임상 질환으로 기능적 자기공명영상(functional MRI, fMRI)를 사용한 많은 연구에서 ASD의 비전형적 인지 과정을 보고하였다. 이를 위해 널리 사용된 방법 중 하나는 전뇌 피질 조직의 대규모 계층 구조를 보여주는 기능적 경향성이다. 그러나 지금까지 대부분의 연구는 외부 자극 없이 내재적 활성화를 보여주는 휴지 상태의 기능적 자기공명영상에 초점을 맞췄다. 이러한 한계를 극복하기 위해 생태학적으로 유효한 환경에서 외인성 활성화를 유도하는 자연적 자극이 주목을 받고 있다. 자연적 자극의 동적 특성은 ASD가 외부세계를 어떻게 이해하는지에 대한 풍부한 정보를 제공한다. 이 연구에서는 영화 시청 중 시간에 따라 ASD가 보여주는 비전형적 기능적 경향성 패턴을 분석하고 이를 통해 ASD가 실제 세계에서 정보를 처리하는 방식을 더 깊이 이해하고자 한다. Autism spectrum disorder (ASD) is a clinical condition that involves perceiving the external world differently. Numerous studies have used functional MRI (fMRI) to analyze the atypical perceptual processing of ASD. One widely used approach is the functional gradient, which demonstrates large-scale principles of cortical organization. However, most studies to date have focused on resting-state fMRI, which captures intrinsic activation without external stimulation. To overcome this limitation, naturalistic stimuli are getting attention that drive exogenous activation in ecologically valid environments. The dynamic characteristics of naturalistic stimuli offer a rich source of information, providing a more complete picture of how autism perceives the external world. In this study, we present an analysis of the time-varying atypical function gradient of ASD during movie-watching fMRI. By examining the dynamics in response to naturalistic stimuli, we aim to gain a deeper understanding of how ASD processes information in the real world.

      • KCI등재후보
      • KCI등재

        場所を表わす助詞「に」と「で」の使い分けの状況

        李宗恩(Lee, Jong-Eun) 대한일어일문학회 2017 일어일문학 Vol.74 No.-

        Japanese particles “に(ni)” and “で(de)” that expresses location correspond to Korean particles “에(e)” and “에서(eseo).” This one-to-one correspondence (“に(ni)” and “에(e),” and “で(de)” and “에서(eseo)”) matches more than 99% of the time. Based on preceding research that classifies the combination of selecting particles into four tendencies: particle is chosen 1. without comprehending the whole context, 2. only looking at the preceding noun that follows the particle, 3. choosing based on prior knowledge learned in school, 4. with fixed knowledge that “ni” follows after explaining the location of nouns and “de” after nouns used for place and building names, the research is then reevaluated for clearer results. Therefore, to analyze the misusage of particles “ni” and “de” to express locations, a survey was conducted on November 2013, with 73 Korean Japanese learners, to look at the correlation with differences in the learning period based on influences from learning and the first language of the learners. Two results can be driven from the evaluation. The first result (influence from learning) is due to memorization of sentence structures, patterns, and set phrases in the early learning stage. This proved the hypothesis that students scored a higher average of correct answers in the beginning stage, backing up Ozeki(2007)’s research results as well. Accordingly, the average of correct answers was higher on choosing “location+ni(に)” over “location+ de(で)” and “place name+de(で)” over “place name+ni(に).” The second result (influence from first language) is that learners learn fixed forms like “~に住む(∼ni sumu)” and “~に泊まる(∼nitomaru)” that learners who already learned the forms are less likely to make the mistakes made by learners in higher level of education. This is contradictory to what Hiromi Ozeki (2007) said that the difference in learner’s first language does not affect the usage and that the tendency of right and wrong usage of Korean Japanese learners is equivalent. As a conclusion, the result of the survey clearly proves that the word usage of particles “ni” and “de” that express location for Korean Japanese learners is largely affected by their mother language.

      • KCI등재

        場所の助詞「に」と「で」の誤用の原因の分析

        李宗恩(Lee, Jong-Eun) 대한일어일문학회 2018 일어일문학 Vol.79 No.-

        Among the particles used in two countries with similar morphology, Japanese particles “に(ni)” and “で(de)” and Korean particles “에(e)“ and”에서(eseo)“ have a common meaning to express location. Particles "ni" and "e" are used to indicate ”place of existence“ and "de" and "eseo" are used to indicate "place where behavior and action occur." A Korean Japanese learner corresponds the particles one to one without difficulty. In doing so, a problem may arise as the correct answer rate surpasses 90%. Therefore, regarding the selection of particles “ni” and “de,” Lee (2017)(2018)’s study shows that Korean Japanese language learners (major, non-major) in the initial learning stage have tendencies to use fixed phrases "position+ni" and "place name+de." In addition, Lee (2017)(2018) backed up the tendency of selection of such particles in precedent study, and clearly supports the results of the usage errors of particles "ni" and "de" to represent place in relation to the influence of learning and of one’s mother tongue through an experiment conducted on November 2013. (Examinees: majors in Busan P. University (73 students), non-majors in Busan K. University (73 students)) Although the method of experiment follows a similar pattern to previous studies of Lee (2017)(2018), this study analyzes the survey conducted on November 2013 and reclassifies the questionnaire based on learning level and not the period of learning. More than 95% of non-major students were excluded form the survey as they do not have a qualified language certificate. The following results were obtained based on the comparison and contrast of location particles “ni” and “de” used by major students of different level. The causes of usage errors can be largely divided into four. ① Difference in level: the accuracy rate of semi-advanced level (N2) learners is slightly higher than advanced level (N1) learners. ② Influence of learning: A: excessive use of "ni" compared to “de” and over-generalization of the fixed phrases "position+ni" and “place name+de.“ (Su et al. (2006)) B: A unit of noun+particle formation is created when selecting particles "ni" and "de." (Noda et al. (2001), Sakuda (2001)) ③ Frequency of learning materials: ”Mae(前)“ and ”naka(中)“ used to represent location comes up fewer times than ”ni“ and ”de“ in ”Minnano Nihongo 1,2.“ ④ Influence of mother tongue: Korean Japanese learners are influenced greatly by the mother tongue in expressions ”to live (~sumu)“ and ”to stay (~tomaru).“ Especially the results that the accuracy rate of beginning level students are ranked slightly higher than semi-advanced to advanced level students in the case of "tomaru" shows discrepancies with the study done by Ozeki (2007).

      • KCI등재
      • 가묘악하선(家猫顎下腺)에 있어서 고색신경(鼓索神經) 및 경부교감신경자극(頸部交感神經刺戟)이 타액분필(唾液分泌) 및 배설관내압(排泄管內壓)에 미치는 영향(影響)

        이종,Lee, Jong-Eun 대한생리학회 1977 대한생리학회지 Vol.11 No.2

        In Nembutal anesthetized cats, the sobmaxillary duct was cannulated with polyethylene tube, and effects of stimulation of the chorda tympani and cervical sympathetics on, the submaxillary secretion and intraluminal pressure of the submaxillary duct were observed. The stimulation of tile chorda tympani elicited a profuse salivary secretion. The stimulation of the cervical sympathetics evoked only a scanty flow, and on repeated stimulation of the nerve salivary flow response gradually diminished and finally the flow ceased. In this state the salivary flow by the sympathetic stimulation was resumed after the stimulation of the chorda tympani. Atropine abolished these responses to nerve stimulation. Intraluminal pressure of the submaxillary duct was abruptly increased and remained on a plateau during the stimulation of the chorda tympani, whereas sympathetic stimulation elicited moderate increase of the intraluminal pressure which did not remain in spite of continued stimulation. These results suggest that scanty salivary flow induced by cervical sympathetic stimulation is not real secretion but simple elimination of the saliva already present in the duct due to contraction of the contractile elements known to exist in the duct wall.

      • 인공관절의 사업화 기회 분석

        이종은(Lee jong-eun),권영일(Kwon young-il) 한국콘텐츠학회 2007 한국콘텐츠학회 종합학술대회 논문집 Vol.5 No.2_1

        인공관절 산업은 기계, 바이오 소재, 의학 기술이 유기적으로 연관을 맺는 복합 산업이다. 인공관절 산업은 고령화 사회에 진입함에 따라 시장 성장이 예상되는 고부가 가치 산업으로, 거의 전량 수입에 의존하는 아이템이므로 국가차원에서 육성이 필요한 지식기반의 부품산업이다. 인공관절 산업은 다양한 소재로 구성된 부품에 기반하고 있으므로, 대기업보다 기술력 있는 중소기업 및 벤처기업의 참여가 많이 이루어지고 있다. 인공관절의 사업화 환경분석에 기반을 두고 사업화 아이템과 사업화 추진전략을 분석하였다. 사업화 환경은 수요, 환경, 기술 요인을 조사하고 성장촉진 및 저해 요인을 도출하였다. 이러한 분석 요인들을 바탕으로 기술에 대한 수요와 기술개발의 발전방향을 분석하여 사업화 아이템을 창출하였고, 이를 종합하여 사업화 추진전략을 분석하였다. 인공관절 산업의 사업화 기회는 통합적인 기술개발시스템 구축, 마케팅 강화, 틈새시장 진출, B2B 전략 등을 기반으로 창출될 수 있을 것으로 전망된다. Industry for artificial joint is a complex one based on various technologies, including mechanics, biotechnology, material engineering, and medicine which are connected closely. This industry has been already known to a higher value-added business, and as going into an aging society, is expected a market growth. Also, it is a knowledge based component industry and each components assembled into product is almost all import items. This characteristics made many small and medium and venture enterprises participate in this area. For these reasons, it is needed a government's promotion. In this study, commercialization environment was analyzed and then commercialization items and strategies was figured out. Firstly, three factors for need, environment, technology were analyzed and then growth drivers growth restraints were provided. Secondly, items and strategies for commercialization were analyzed based on needs and trends of technology. Commercialization opportunities are expected to be created based on strategies following as; building a integrated technology development system, making a public opinion, strengthening a marketing, entering into niche market, B2B strategies etc.

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