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Na Kyeong Ik,Lee Won June,Kim Young Kook 대한의학회 2023 Journal of Korean medical science Vol.38 No.28
Background: Contemporary data on vision impairment form an important basis for public health policies. However, most data on the clinical epidemiology of blindness are limited by small sample sizes and focused not on systemic conditions but ophthalmic diseases only. In this study, we examined the ten-year trends of blindness prevalence and its correlation with systemic health status in Korean adults. Methods: This study investigated 10,000,000 participants randomly extracted from the entire Korean population (aged ≥ 20 years) who underwent a National Health Insurance Service health checkup between 2009 and 2018. Participants with blindness, defined as visual acuity in the better-seeing eye of ≤ 20/200, were identified. The prevalence of blindness was assessed, and the systemic health status was compared between participants with blindness and without blindness. Results: The mean prevalence of blindness was 0.473% (47,115 blindness cases) and tended to decrease over ten years (0.586% in 2009 and 0.348% in 2018; P < 0.001). The following factors were significantly associated with blindness: female sex, underweight (body mass index < 18.5), high serum creatinine (> 1.5 mg/dL), and bilateral hearing loss. In addition, except for those aged 30–39 and 40–49 years, high fasting glucose (≥ 126 mg/dL) and low hemoglobin (male: < 12 g/dL, female: < 10 g/dL) were significantly correlated with prevalent blindness. Conclusion: Our ten-year Korean nationwide population-based study suggested a gradual decrease in the prevalence of blindness and its association with specific systemic health status. These conditions might be the cause or consequence of blindness and can be used as a reference for the prevention and/or rehabilitation of blindness to establish public health policies.
Ik Sang Shin,Ki Hong Sim,Duck Young Hwang,Kyeong Ho Jang,Sin Hye Na,박평렬 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.69 No.3
Unlike the NbTi superconducting wires used for high critical current density, NbTi wires for Magnetic resonance imaging (MRI) magnets have larger and fewer NbTi monofilaments and different cross sections, which show different superconducting properties. This study investigated the effects of varying the temperature, number of heat-treatment cycles, and total strain over a wide range for multifilamentary Nb-46.5%Ti wires on a mass production scale for use in MRI magnets. The heat-treatment conditions were optimized for an NbTi superconducting wire and the critical current density and the n-value were measured as functions of the final strain at temperatures of 4.2 K and 7 T. We noticed that the superconducting properties increased with increasing final strain of the multifilamentary NbTi wire. The microstructure and the effects of the size and the distribution of -Ti precipitates on the individual heat-treatment steps were observed by using transmission electron microscopy (TEM) and scanning electron microscopy (SEM). We, consequently, found the heat-treatment conditions that provided the highest superconducting performance for the two types of NbTi wires used in this study, and the results of the study are expected to very helpful in establishing not only the heat-treatment conditions but also important manufacturing parameters, such as the total strain, even as the design of NbTi wires for used in MRI magnets as changing with industrial demand.
Development of New Vitrification Method for Preimplantation Mouse Embryo
A-Na Ha,Md. Fakruzzaman,Kyeong-Lim Lee,Erdan Wang,Jae-Ik Lee,Chan-Sik Min,Il-Keun Kong 韓國受精卵移植學會 2013 한국동물생명공학회지 Vol.28 No.2
The purpose of this study was attempted to new methods in mammalian embryos vitrification. This method was affected to increase of the embryo vitrification efficiency and it would be applied to the field of embryo transfer to recipient by modified loading method of embryo into 0.25 ml plastic straw. The frozen mouse embryos were carried out warmed from two different cell stages (8-cell and blastocyst, respectively) by attachment of an embryo in the vitrification straw (aV) method. All groups were cultured in M-16 medium to determine the development and survivability for 24 h, respectively. Results shown that, the survivability of two different groups were significantly different (94.8% vs. 70.9%). Total cell number was not significantly different the non-frozen blastocyst (99.7 ± 12.4) compared to the post-thaw blastocyst (94.8 ± 15.1). From the 8-cell embryo, total cell number of frozen blastocysts were significantly lower than others groups (74.7 ± 14.6, p<0.05). In the case of cell death analysis, the blastocysts from non-frozen and frozen-thawed 8-cell group were not different (0.0 ± 0.0 vs. 1.9 ± 3.1, p>0.05). However, the apoptotic nuclei of blastocyst were significantly observed the frozen-thawed group (5.4 ± 4.4) compared to non-frozen group (p<0.05). Therefore, this new method of embryos using in-straw dilution and direct transfer into other species would be more simple procedure of embryo transfer rather than step-wise dilution method and cryopreservation vessels, so we can be applied in animal as well as human embryo cryopreservation in further.
나경익,이주연,Kyeong Ik Na,Joo Yeon Lee 대한안과학회 2012 대한안과학회지 Vol.53 No.9
Purpose: To evaluate the progress and outcome of consecutive esotropia after surgery for intermittent exotropia. Methods: The authors investigated the risk factors, changes in the angle of esodeviation and treatment outcome in consecutive esotropia after lateral rectus muscle recession for intermittent exotropia in 196 patients. Results: Consecutive esotropia occurred in 25 patients (12.8%). The patients underwent more frequent combined muscle surgeries on vertical and oblique muscles (p = 0.001) and had a greater amount of immediate postoperative overcorrection than subjects without consecutive esotropia. There was no significant difference with the incidence of overcorrection greater than 17 PD between the 2 groups with and without consecutive esotropia. There was no difference with the immediate postoperative overcorrection between the 6 cases that required surgery for their consecutive esotropia and the cases that recovered from their consecutive esotropia with conservative treatment. The former showed increasing esodeviation and maximum angle at average postoperative month 29.5. In the latter, esodeviation tended to decrease and showed maximum angle at average postoperative month 4.3. Finally, esotropia disappeared and good stereoacuity was obtained in both cases. Conclusions: Although subjects with consecutive esotropia had a greater immediate postoperative overcorrection than subjects without consecutive esotropia, the progress and outcome of consecutive esotropia following the initial overcorrection were not predictable. Consecutive esotropia after surgery for intermittent exotropia showed good overall outcome and well‐preserved stereoacuity after treatment. J Korean Ophthalmol Soc 2012;53(9):1318-1323
Development of New Vitrification Method for Preimplantation Mouse Embryo
Ha, A-Na,Fakruzzaman, Md.,Lee, Kyeong-Lim,Wang, Erdan,Lee, Jae-Ik,Min, Chan-Sik,Kong, Il-Keun The Korean Society of Embryo Transfer 2013 한국동물생명공학회지 Vol.28 No.2
The purpose of this study was attempted to new methods in mammalian embryos vitrification. This method was affected to increase of the embryo vitrification efficiency and it would be applied to the field of embryo transfer to recipient by modified loading method of embryo into 0.25 ml plastic straw. The frozen mouse embryos were carried out warmed from two different cell stages (8-cell and blastocyst, respectively) by attachment of an embryo in the vitrification straw (aV) method. All groups were cultured in M-16 medium to determine the development and survivability for 24 h, respectively. Results shown that, the survivability of two different groups were significantly different (94.8% vs. 70.9%). Total cell number was not significantly different the non-frozen blastocyst ($99.7{\pm}12.4$) compared to the post-thaw blastocyst ($94.8{\pm}15.1$). From the 8-cell embryo, total cell number of frozen blastocysts were significantly lower than others groups ($74.7{\pm}14.6$, p<0.05). In the case of cell death analysis, the blastocysts from non-frozen and frozen-thawed 8-cell group were not different ($0.0{\pm}0.0$ vs. $1.9{\pm}3.1$, p>0.05). However, the apoptotic nuclei of blastocyst were significantly observed the frozen-thawed group ($5.4{\pm}4.4$) compared to non-frozen group (p<0.05). Therefore, this new method of embryos using in-straw dilution and direct transfer into other species would be more simple procedure of embryo transfer rather than step-wise dilution method and cryopreservation vessels, so we can be applied in animal as well as human embryo cryopreservation in further.
김민경,권은지,김익동,백수정,이미나,이윤주,장혜숙,최선미 연세대학교 생활과학대학 1989 婦學 Vol.22 No.-
The Purpose of this study was to offer clothing design for children when playing out doors using nonwoven fabrics by investigating the clothing behaviors of mothers and children. The data was collected through questionnaire survey method. The results were as follows. 1. Mothers took a serious view of comfort and utility for clothes of children 2. In color design, there was significant difference in preference of boys and girls. On the basis of the results, design of childrens clothing using nonwoven fabrics were suggested.
전신마취 후 발생한 양안 급성폐쇄각녹내장에 동반한 비동맥염 앞허혈시신경병증
박동희(Donghee Park),나경익(Kyeong Ik Na) 대한검안학회 2020 Annals of optometry and contact lens Vol.19 No.4
Purpose: To report a case of bilateral nonarteritic anterior ischemic optic neuropathy (NAION) following acute angle closure glaucoma (AACG) after general anesthesia. Case summary: A 65-year-old woman, who had had open reduction and internal fixation under general anesthesia for her right femur fracture, presented with a 2-day history of visual loss in both eyes. Best corrected visual acuity was finger count and intraocular pressure (IOP) was 40 mmHg in her both eyes. There were diffuse corneal edema and shallow peripheral anterior chamber under slit lamp examination, and fundus examination revealed a swollen optic disc in both eyes. With no lesion found in emergent brain magnetic resonance imaging, optical coherence tomography (OCT) showed diffuse retinal nerve fiber layer (RNFL) thickening. She started glaucoma medications for lowering IOP and laser iridotomy was performed in her both eyes. Two months later, optic disc swelling was improved but OCT showed diffuse RNFL thinning in both eyes and peripheral visual field defects remained in the visual field test. Conclusions: Either stress by general anesthesia or several drugs given after the operation can be attributed to bilateral AACG. Acute rises in IOP may lead to bilateral NAION by decreasing optic nerve head perfusion pressure, which results in ischemia of the optic disc.
Developmental Efficiency of Bovine SCNT Embryos from the Cells with Arhgap15 Gene Knock-Down
Byoung-Chul Yang,Hwi-Cheul Lee,Seongsoo Hwang,Jae-Seok Woo,Ik-Soo Jeon,Dong-Kyeong Lee,Na-Yeong Gu,Jin-Hee An,Young-Joon Han,Eun-Young Kim,Soo-Bong Park 한국동물생명공학회(구 한국동물번식학회) 2010 Reproductive & developmental biology Vol.34 No.2