유방암과 관련된 부수종양성 Stiff-Person Syndrome 1예

방현,이상암,최은정,김광국,박성혜 대한신경과학회 1999 대한신경과학회지 Vol.17 No.5

프로그래머블 콘트롤러의 하드웨어 및 소프트웨어 연구

김현기,우광방 연세대학교 산업기술연구소 1985 논문집 Vol.17 No.2

With the advent of microprocessor, many types of programmable controllers (PC) have been developed and utilized for large plants. The need for the PC which is applicable for part line of large plants, even for small plant, is increasing. In this paper, the PC using Motorola, MC14500B 1-bit microprocessor was designed specifically for sequencing and on/off control to which arithmetic computation is not essential. The users could easily program sequential operations only with Industrial Control Unit (ICU) instructions. The simple programming language was defined and a compiler was provided for easy programming. The performance characteristics of the designed PC with a 1-bit microprocessor indicate the following results; 1. For the scan time and price, the 1-bit ICU based PC was more efficient than the one using multi-bit micro-processor in/off sequence control. 2. For the modularization the 1-bit ICU based PC could be easily realized over the binary decision method based PC. For the software, the 1 bit ICU based PC is simple where the BD based PC is more complicated because of the requirement of the high level knowledge of BD method.

조갑진균증에서 Ciclopirox Nail Lacquer의 치료효과

박경찬,김정애,방형돈,조광현,윤재일,김병수 대한감염학회 1995 감염 Vol.27 No.3

배경 및 목적:조갑진균증의 치료에 있어 국소용 항진균제는 조갑판을 통과하지 못하기 때문에 치료율이 낮은 것으로 알려졌으나 최근 조갑판을 통과하여 조상에서도 높은 치료농도를 유지할 수 있는 국소용 항진균제인 ciclopirox nail lacquer가 개발되었다. 이에 본 저자들은 8% ciclopirox nail lacquer 단독 도포의 조갑진균증에서의 치료 효과와 안전성을 알아 보기 위한 연구를 수행하였다. 방법:표적 조갑판의 감염된 면적의 비율이 50%이하인 경증의 조갑진균증 환자 27명을 평가 대상으로 하였으며 8% ciclopirox nail lacquer 1일 1회 도포요법으로 6개월간 치료하였다. 매 방문시마다 감염면적 비율을 기록하였고 치료 전과 치료 후 진균 검사를 시행하였다. 결과: 1)표적조갑판의 감염 면적이 치료 전 평균 28.9%에서 치료 종료시 4.7%로 통계적으로 유의하게 감소하였다(p<0.001). 2)KOH 직접 도말 검사와 진균 배양 검사에서 모두 음성인 진균학적 완치율은 치료 종료시 77.8%였다. 3)부작용으로는 3명(11.1%)에서 일시적 작열감, 조갑 감입 등을 호소하였다. 결론:경증의 조갑진균증 치료에 있어 8% ciclopirox nail lacquer는 비교적 좋은 치료 효과를 보이며 부작용이 적은 약제로 생각된다. Background: Topical antifungal agents have been ineffective in the treatment of onychomycosis because they could not reach the infected nail bed. 8% ciclopirox nail lacquer is a new topical antimycotic which is characterized by excellent penetration into the nail plate. We performed a study to assess the therapeutic efficacy and safety of 8% ciclopirox nail lacquer in the treatment of onychomycosis. Methods: We assessed 27 onychomycotic patients whose affected area of target nail plate was not more than 50%. The patients were instructed to apply 8% ciclopirox nail lacquer once daily and evaluated monthly for 6 months. Mycological examinations were done before and after the treatment. Overall efficacy, tolerability, cosmetic acceptance and adverse effects were assessed at the end of 6 months' treatment. Results: The mean percentage of affected area decreased from 28.9% to 4.7%. Mycological cure rate was 77.8% at the end of the treatment. Overall efficacy assessed by physician and patients were similar and evaluated as complete cure in 48% and 44%, respectively. Tolerability and cosmetic acceptance were excellent or good in most of the patients. No systemic adverse effects were found, but 3 patients complained of mild prickling sensation or ingrowing toe nail. Conclusions: These data suggest that 8% ciclopirox nail lacquer is safe and effective in the treatment of mild onychomycosis.

Comparison of the in vivo and in vitro dermal absorption rate of Spinosad

Ji-Hyun Bang(Ji-Hyun Bang),Hyun-Ok Ku(Hyun-Ok Ku),Byung-Suk Jeon(Byung-Suk Jeon),Hyobi Kim(Hyobi Kim),Kwang-Jick Lee(Kwang-Jick Lee),Yong-Sang Kim(Yong-Sang Kim),Hee Yi(Hee Yi) 한국예방수의학회 2019 한국예방수의학회 학술대회자료집 Vol.2018 No.-

Prediction of skin penetration of Bifenthrin using in vitro micro-pig skin model

Ji-Hyun Bang(Ji-Hyun Bang),Hyun-Ok Ku(Hyun-Ok Ku),Byung-Suk Jeon(Byung-Suk Jeon),Hyobi Kim(Hyobi Kim),Kwang-Jick Lee(Kwang-Jick Lee),Yong-Sang Kim(Yong-Sang Kim),Hee Yi(Hee Yi) 한국예방수의학회 2019 한국예방수의학회 학술대회자료집 Vol.2018 No.-

ENHANCEMENT OF DRYOUT HEAT FLUX IN A DEBRIS BED BY FORCED COOLANT FLOW FROM BELOW

Bang, Kwang-Hyun,Kim, Jong-Myung Korean Nuclear Society 2010 Nuclear Engineering and Technology Vol.42 No.3

In the design of advanced light water reactors (ALWRs) and in the safety assessment of currently operating nuclear power plants, it is necessary to evaluate the possibility of experiencing a degraded core accident and to develop innovative safety technologies in order to assure long-term debris cooling. The objective of this experimental study is to investigate the enhancement factors of dryout heat flux in debris beds by coolant injection from below. The experimental facility consists mainly of an induction heater, a double-wall quartz-tube test section containing a steel-particle bed and coolant injection and recovery condensing loop. A fairly uniform heating of the particle bed was achieved in the radial direction and the axial variation was within 20%. This paper reports the experimental data for 3.2 mm and 4.8 mm particle beds with a 300 mm bed height. The dryout heat density data were obtained for both the top-flooding and the forced coolant injection from below with an injection mass flux of up to $1.5\;kg/m^2s$. The dryout heat density increased as the rate of coolant injection increased. At a coolant injection mass flux of $1.0\;kg/m^2s$, the dryout heat density was ${\sim}6.5\;MW/m^3$ for the 4.8 mm particle bed and ${\sim}5.6\;MW/m^3$ for the 3.2 mm particle bed. The enhancement factors of the dryout heat density were 1.6-1.8.

An Assessment of Reactor Vessel Integrity Under In-Vessel Vapor Explosion Loads

Bang, Kwang-Hyun,Cho, Jong-Rae,Park, Soo-Yong Korean Nuclear Society 2000 Nuclear Engineering and Technology Vol.32 No.4

A safety assessment of reactor vessel lower head integrity under in-vessel vapor explosion loads has been performed. The core melt relocation parameters were chosen within the ranges of physically realizable bounds. The premixing and explosion calculations were performed using TRACER-II code. Using the calculated explosion pressures imposed on the lower head inner wall, strain calculations were peformed using ANSYS code. Then, the calculated strain results and the established failure criteria were used in determining the failure probability of the lower head, In the explosion analyses, it is shown that the explosion impulses are not altered significantly by the uncertain parameters of triggering location and time, fuel and vapor volume fractions in uniform premixture bounding calculations. Strain analyses show that the vapor explosion-induced lower head failure is not possible under the present framework of assessment. The result of static analysis using the conservative explosion-end pressure of 50 MPa also supports the conclusion. It is recommended, however, that an assessment of fracture mechanics for preexisting cracks be also considered to obtain a more concrete conclusion.

English Speaking Session : Pigmented Nail with Atypical Melanocytic Hyperplasia

( Kwang Hyun Cho ),( Bang Soon Kim ),( Seung Ho Chang ),( Yoo Shin Lee ),( Kwang Joong Kim ) 대한피부과학회 1991 초록집 Vol.29 No.20

Thermodynamic Analysis of Vapor Explosion Phenomena

Bang, Kwang-Hyun Korean Nuclear Society 1993 Nuclear Engineering and Technology Vol.25 No.2

A vapor explosion has been a concern in nuclear reactor safety due to its potential for a destructive mechanical energy release. In order to properly assess the hazard of a vapor explosion, it is necessary to accurately estimate the conversion efficiency of the thermal energy to mechanical energy. In the absence of a complete model to determine the explosive energy yield, one may have to rely on a simpler upper bound estimate such as a thermodynamic model. This paper discusses various thermodynamic models and presents a clarification of each model in their mathematical formulation and the thermodynamic work conversion. It is shown that the work release in the shock adiabatic model of Board and Hall is essentially equal to that of Hicks-Menzies thermodynamic model. The effect of coolant void fraction on the explosion efficiency is also predicted based on these thermodynamic models. Finally, the Hicks-Menzies model is modified to account for the chemical reaction between a metallic fuel and water and the resultant effects on the explosion expansion work are discussed.

Minimum Film Boiling Temperatures for Spheres in Dilute Aqueous Polymer Solutions and Implications for the Suppression of Vapor Explosions

Bang, Kwang-Hyun,Jeun, Gyoo-Dong Korean Nuclear Society 1995 Nuclear Engineering and Technology Vol.27 No.4

Pool boiling of dilute aqueous solutions of polyethylene oxide polymer has been experimentally investigated for the purpose of understanding the physical mechanisms of the suppression of vapor explosions in this polymer solution. Tn solid spheres of 22.2mm and 9.5mm-diameter ore heat-ed and quenched in the polymer solutions of various concentrations at 3$0^{\circ}C$. The results showed that minimum film boiling temperature($\Delta$ $T_{MFB}$) in this highly-subcooled liquid rapidly decreased from over $700^{\circ}C$ for pure water to about 15$0^{\circ}C$ as the polymer concentration was increased up to 300ppm for 22.2mm sphere, and it decreased to 35$0^{\circ}C$ for 9.5mm sphere. This large decrease of minimum film boiling temperature in this aqueous polymer solution may explain its ability to suppress spontaneous vapor explosions. Also, tests with applying a pressure wave showed that the vapor film behaved more stable against an external disturbance at higher polymer concentrations. These observations together with the experimental evidences of vapor explosion suppression in dilute polymer solutions suggest that the application of polymeric additives such as polyethylene oxide as low as 300ppm to reactor emergency coolant be considered to prevent or mitigate energetic fuel-coolant interactions during severe reactor accidents.s.