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Final report on force key comparison CCM.F-K2.a and CCM.F-K2.b (50 kN and 100 kN)
Vincke, William,Zhimin, Zhang,Pusa, Aimo,Averlant, Philippe,Kumme, Rolf,Germak, Alessandro,Ueda, Kazunaga,Park, Yon-Kyu,Torres, Jorge,Burke, Ben,Langmead, Fredrik,Fank, Sinan,Knott, Andy,Bartel, Tom Springer-Verlag 2012 METROLOGIA -BERLIN- Vol.49 No.-
<P>This report describes CIPM key comparison CCM.F-K2, a comparison between the deadweight force standard machines of fourteen National Measurement Institutes, at generated forces of 50 kN and 100 kN, in the period from 2004 to 2007. Two different measurement schemes were employed, one for machines capable of generating both 50 kN and 100 kN and the other using the single force of 50 kN, for machines of a lower maximum capacity than 100 kN. Multiple transducers were used and the force–time profile was strictly controlled, to minimize effects of creep. Analysis of the results took careful account of the drift of the transducers' sensitivities throughout the comparison period, as this was one of the major uncertainty contributions. The final results suggest that the nominal 50 kN forces generated at four of the fourteen laboratories (and the 100 kN forces at two of them) may be statistically significantly different from the same nominal forces generated at the other laboratories.</P><P>Main text.To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/.</P><P>The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).</P>
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Elahi, Elahe,Kumm, Jochen,Ronaghi, Mostafa 한국생화학분자생물학회 2004 BMB Reports Vol.37 No.1
The introduction of molecular markers in genetic analysis has revolutionized medicine. These molecular markers are genetic variations associated with a predisposition to common diseases and individual variations in drug responses. Identification and genotyping a vast number of genetic polymorphisms in large populations are increasingly important for disease gene identification, pharmacogenetics and population-based studies. Among variations being analyzed, single nucleotide polymorphisms seem to he most useful in large-scale genetic analysis. This review discusses approaches for genetic analysis, use of different markers, and emerging technologies for large-scale genetic analysis where millions of genotyping need to be performed.
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Elahi, Elahe,Kumm, Jochen,Ronaghi, Mostafa Korean Society for Biochemistry and Molecular Biol 2004 Journal of biochemistry and molecular biology Vol.37 No.1
The introduction of molecular markers in genetic analysis has revolutionized medicine. These molecular markers are genetic variations associated with a predisposition to common diseases and individual variations in drug responses. Identification and genotyping a vast number of genetic polymorphisms in large populations are increasingly important for disease gene identification, pharmacogenetics and population-based studies. Among variations being analyzed, single nucleotide polymorphisms seem to be most useful in large-scale genetic analysis. This review discusses approaches for genetic analysis, use of different markers, and emerging technologies for large-scale genetic analysis where millions of genotyping need to be performed.
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Antityrosinase and antimicrobial activities from Thai medicinal plants
Dej-adisai, Sukanya,Meechai, Imron,Puripattanavong, Jindaporn,Kummee, Sopa 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.4
Various dermatological disorders and microbial skin infection can cause hyperpigmentation. Therefore, screenings for whitening and antimicrobial agents from Thai medicinal plants have been of research interest. Seventy-seven ethanol plant extracts were investigated for antityrosinase activity, eleven samples showed the tyrosinase inhibition more than 50 % were further preliminary screening for antimicrobial activity by agar disc diffusion and broth micro-dilution methods. Artocarpus integer (Thunb.) Merr. (Moraceae) root extract, which showed the potential of tyrosinase inhibition with $90.57{\pm}2.93%$ and antimicrobial activity against Staphylococcus aureus, S. epidermidis, Propionibacterium acnes and Trichophyton mentagophytes with inhibition zone as $9.10{\pm}0.00$, $10.67{\pm}0.09$, $15.25{\pm}0.05$ and $6.60{\pm}0.17mm$, respectively was selected for phytochemical investigation. Three pure compounds were isolated as artocarpin, cudraflavone C and artocarpanone. And artocarpanone exhibited antityrosinase effect; artocarpin and cudraflavone C also showed the potential of antibacterial activity against S. aureus, S. epidermidis and P. acnes with MIC at 2, 4 and $2{\mu}g/ml$, respectively and MBC at $32{\mu}g/ml$ for these bacteria. So, these pure compounds are interesting for further study in order to provide possibilities of new whitening and antibacterial development. This will be the first report of phytochemical investigation of A. integer root.
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Antityrosinase and antimicrobial activities from Thai medicinal plants
Sukanya Dej-adisai,Imron Meechai,Jindaporn Puripattanavong,Sopa Kummee 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.4
Various dermatological disorders and microbialskin infection can cause hyperpigmentation. Therefore,screenings for whitening and antimicrobial agents fromThai medicinal plants have been of research interest. Seventy-seven ethanol plant extracts were investigated for antityrosinaseactivity, eleven samples showed the tyrosinaseinhibition more than 50 % were further preliminaryscreening for antimicrobial activity by agar disc diffusionand broth micro-dilution methods. Artocarpus integer(Thunb.) Merr. (Moraceae) root extract, which showed thepotential of tyrosinase inhibition with 90.57 ± 2.93 %and antimicrobial activity against Staphylococcus aureus,S. epidermidis, Propionibacterium acnes and Trichophytonmentagophytes with inhibition zone as 9.10 ± 0.00,10.67 ± 0.09, 15.25 ± 0.05 and 6.60 ± 0.17 mm, respectivelywas selected for phytochemical investigation. Threepure compounds were isolated as artocarpin, cudraflavoneC and artocarpanone. And artocarpanone exhibited antityrosinaseeffect; artocarpin and cudraflavone C alsoshowed the potential of antibacterial activity againstS. aureus, S. epidermidis and P. acnes with MIC at 2, 4 and2 lg/ml, respectively and MBC at 32 lg/ml for these bacteria. So, these pure compounds are interesting for furtherstudy in order to provide possibilities of new whitening andantibacterial development. This will be the first report ofphytochemical investigation of A. integer root.
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