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      • SCOPUSKCI등재

        Muscle-Sparing Blepharoplasty: A Prospective Left-Right Comparative Study

        Kiang, Lee,Deptula, Peter,Mazhar, Momal,Murariu, Daniel,Parsa, Fereydoun Don Korean Society of Plastic and Reconstructive Surge 2014 Archives of Plastic Surgery Vol.41 No.5

        Background Standard upper blepharoplasty involves removal of both the skin and a portion of the underlying orbicularis oculi muscle. The senior author had observed sluggishness of eyelid closure, lagophthalmos as well as varying degrees of eye irritation in certain patients during the early postoperative period. He postulated that these findings could be due to orbicularis muscle excision. He therefore undertook a prospective study 27 years ago comparing standard blepharoplasty on one eyelid to skin-only excision on the fellow eyelid. Methods A randomized, prospective, single-blinded study was designed using the fellow eye as an internal control. 22 patients undergoing upper blepharoplasty procedure requiring greater than 5 mm of skin resection and with no history of ophthalmologic disease, dry eye, or previous eyelid surgery were selected. Upper blepharoplasty was performed with skin-only removal on one side, and combined skin-muscle removal on the other side. Patients were evaluated until six months after surgery except for two patients who were lost to follow-up after three months. Sluggish eyelid closure, lagophthalmos, dry eye and aesthetic result were outcome measures scored by patient survey, the operating surgeon, and a blinded expert panel. Results There were comparable aesthetic outcomes in both eyelids. The incidence of sluggish eyelid closure, lagophthalmos and dry eye syndrome were significantly higher in eyelids where wide segments of muscle had been resected. Conclusions Muscle-sparing upper blepharoplasty produces similar aesthetic outcomes as conventional blepharoplasty, while significantly reducing the complications of sluggish eyelid closure, lagophthalmos and dry eye disease. The authors therefore recommend muscle-sparing upper blepharoplasty.

      • KCI등재

        不平均的福音 -對天主敎民初在華傳播的空間特徵與牧衆比例的量化考察(고르지 않은 복음 -민초 중국 천주교의 공간 특징과 성직자 비율의 계량적 연구)

        키앙치호 ( Kiang Chi Ho ) 중국사학회 2017 中國史硏究 Vol.111 No.-

        서구 물결이 동방으로 크게 밀려 들어 오던 근대 시기에 선교사들의 중국에서의 활동과 그 영향은 항상 하계에서 중시되어 왔다. 그중에서도 개신교에 관한 연구는 많이 이루어져 왔으나 아직 중국에서의 천주교의 활동에 대한 연구는 추가 검토의 여지가 남아 있다. 기존의 연구는 주로 개별 수도회나 지역 단위의 개별 연구에 집중되어 있으며 민국 초기 천주교의 중국에서의 전반적인 공간적 구조에 관해서는 상대적으로 부족한 편이다. 이 논문은 천주교가 중국에 들어오게 되는 경위를 간략히 살펴본 다음, 1920년대에 중국 주재 일본 외교관이 찬술한 「歐美人在華文化事業槪論」의 조사 보고 통계를 근거로 하여 이 시기 천주교가 중국에서 재원을 투입한 총량과 그 지리적 초점을 검토하였다. 그리고 중국에 개신교가 전파된 상황과 대조하면서 성직자와 교인들 수와의 상관성을 바탕으로 계량적 수치에 근거하여 해석을 시도하였다.

      • SCIESCOPUSKCI등재

        Glass FRP-Bonded RC Beams under Cyclic Loading

        Tan, Kiang-Hwee,Saha, Mithun-Kumar Korea Concrete Institute 2007 International Journal of Concrete Structures and M Vol.1 No.1

        Ten beams bonded with glass fiber reinforced polymer (GFRP) laminates were tested under cyclic loading with the load range and the FRP reinforcement ratio as test parameters. The maximum load level during cyclic loading was 55%, 65% and 75% of the static flexural strength while the minimum load level was kept constant at 35%. Deflections of the beams at the end of 525000 cycles were found to increase by 16% and 44% when the maximum load level was increased from 55% to 65% and 75% of the static flexural strength, respectively. Beams with FRP reinforcement ratios of 0.64% and 1.28% were found to exhibit lesser deflections of about 15% and 20%, respectively, compared to a similar beam without FRP reinforcement. An analytical approach based on cycle-dependent effective moduli of elasticity of concrete and FRP reinforcement is presented and found to predict the deflections of the test beams well.

      • KCI등재

        Muscle-Sparing Blepharoplasty: A Prospective Left-Right Comparative Study

        Lee Kiang,Peter Deptula,Momal Mazhar,Daniel Murariu,Fereydoun Don Parsa 대한성형외과학회 2014 Archives of Plastic Surgery Vol.41 No.5

        Background: Standard upper blepharoplasty involves removal of both the skin and a portionof the underlying orbicularis oculi muscle. The senior author had observed sluggishness ofeyelid closure, lagophthalmos as well as varying degrees of eye irritation in certain patientsduring the early postoperative period. He postulated that these findings could be due toorbicularis muscle excision. He therefore undertook a prospective study 27 years agocomparing standard blepharoplasty on one eyelid to skin-only excision on the fellow eyelid. Methods: A randomized, prospective, single-blinded study was designed using the fellow eyeas an internal control. 22 patients undergoing upper blepharoplasty procedure requiringgreater than 5 mm of skin resection and with no history of ophthalmologic disease, dry eye, orprevious eyelid surgery were selected. Upper blepharoplasty was performed with skin-onlyremoval on one side, and combined skin-muscle removal on the other side. Patients wereevaluated until six months after surgery except for two patients who were lost to follow-upafter three months. Sluggish eyelid closure, lagophthalmos, dry eye and aesthetic result wereoutcome measures scored by patient survey, the operating surgeon, and a blinded expert panel. Results: There were comparable aesthetic outcomes in both eyelids. The incidence of sluggisheyelid closure, lagophthalmos and dry eye syndrome were significantly higher in eyelidswhere wide segments of muscle had been resected. Conclusions: Muscle-sparing upper blepharoplasty produces similar aesthetic outcomes asconventional blepharoplasty, while significantly reducing the complications of sluggish eyelidclosure, lagophthalmos and dry eye disease. The authors therefore recommend muscle-sparing upper blepharoplasty.

      • KCI등재

        Khmer American Mothers' Knowledge about HPV and HBV Infection and Their Perceptions of Parenting: My English Speaking Daughter Knows More

        이해옥,Peter Kiang,Shirely S. Tang,Phala Chea,Sonith Peou,Semira Semino-Asaro,Dorcas C. Grigg-Saito 한국간호과학회 2015 Asian Nursing Research Vol.9 No.2

        Purpose: The purpose of this study is to explore and describe Khmer mothers' understanding of HBV and HPV prevention as well as their perception of parenting on health and health education of their daughters in the US. Methods: The qualitative pilot study guided by the revised Network Episode Model and informed by ethnographic analysis and community-based purposive sampling method were used. Face-to-face audiotaped interviews with eight Khmer mothers were conducted by bilingual female middle-aged community health leaders who spoke Khmer. Results: The findings revealed that Khmer mothers clearly lacked knowledge about HBV and HPV infection prevention and had difficulty understanding and educating their daughters about health behavior, especially on sex-related topics. The findings showed that histo-sociocultural factors are integrated with the individual factor, and these factors influenced the HBV and HPV knowledge and perspective of Khmer mothers' parenting. Conclusions: The study suggests that situation-specific conceptual and methodological approaches that take into account the uniqueness of the sociocultural context of CAs is a novel method for identifying factors that are significant in shaping the perception of Khmer mothers' health education related to HBV and HPV prevention among their daughters. The communication between mother and daughter about sex and the risk involved in contracting HBV and HPV has been limited, partly because it is seen as a “taboo subject” and partly because mothers think that schools educate their children regarding sexuality and health.

      • KCI등재
      • KCI등재

        The Association of Long Noncoding RNA LOC105372577 with Endoplasmic Reticulum Protein 29 Expression: A Genome-wide Association Study

        이소연,권기상,고영화,권오유,Lee, Soyeon,Kwon, Kiang,Ko, Younghwa,Kwon, O-Yu Korean Society of Life Science 2021 생명과학회지 Vol.31 No.6

        본 연구는 전장 유전체 연관성 분석(genome-wide association study, GWAS)을 통해 ERp29의 mRNA 발현과 관련된 유전좌위(expression quantitative trait loci, eQTL)을 식별하는 것을 목표로 하였다. 대상 유전자는 ERp29이다. ERp29는 소포체(ER)의 lumen에 단백질의 folding & assembly 기능을 가진 분자 chaperone 단백질로서 소포체 스트레스에 의해 발현량이 증가하며, 분비 단백질의 생합성에 관여한다. 최근 연구 결과 발암과 연관성이 알려지면서 주목을 받고 있다. 총 373명의 유럽인의 genome을 대상으로 GWAS 분석 결과, ERp29 유전자 발현은 정소와 뇌에서 강하게 발현하는 long noncoding RNA (LncRNA) LOC105372577과 관계가 있었다. 즉, 3개의 eQTL: rs6138266 (p<4.172e10-9), rs62193420 (p<1.173e10-8), rs6138267 (p<2.041e10-8)와 연관성이 깊은 것으로 밝혀졌다. ERp29의 발현과 연관이 있는 것으로 확인된 3개의 eQTL을 사용한 transcriptome-wide association study (TWAS) 결과 osteosarcoma amplified 9 (OS9) 발현과 유의한 연관성을 보이며 OS9 유전자의 up-stream에 upstream of transcription factor 1 (USF1)이 결합할 수 있는 것을 알았다. This study identified genomic factors associated with endoplasmic reticulum protein (ERp)29 gene expression in a genome-wide association study (GWAS) of genetic variants, including single-nucleotide polymorphisms (SNPs). In total, 373 European genes from the 1000 Genomes Project were analyzed. SNPs with an allelic frequency of less than or more than 5% were removed, resulting in 5,913,563 SNPs including in the analysis. The following expression quantitative trait loci (eQTL) from the long noncoding RNA LOC105372577 were strongly associated with ERp29 expression: rs6138266 (p<4.172e10), rs62193420 (p<1.173e10), and rs6138267 (p<2.041e10). These were strongly expressed in the testis and in the brain. The three eQTL were identified through a transcriptome-wide association study (TWAS) and showed a significant association with ERp29 and osteosarcoma amplified 9 (OS9) expression. Upstream sequences of rs6138266 were recognized by ChIP-seq data, while HaploReg was used to demonstrate how its regulatory DNA binds upstream of transcription factor 1 (USF1). There were no changes in the expression of OS9 or USF1 following ER stress.

      • 초기 디자인 단계에서의 사용자 관찰을 통한 인터렉티브 공공디스플레이 개발

        염정호(Jung-Ho Yeom),Beng-Kiang Tan 한국HCI학회 2012 한국HCI학회 학술대회 Vol.2012 No.1

        대형 디스플레이 기술의 발달로 정보 공유 목적의 공공디스플레이들이 공공장소를 중심으로 설치되고있다. 최근의 공공디스플레이들은 기존의 단방향 적인 정보제공에서 벗어나 사용자들에 의해 선택된 정보를 제공해주거나 사용자가 직접 참여할 수 있는 양방향의 커뮤니케이션 서비스들을 제공하는 추세이다. 본 연구에서는 사용자의 참여를 통한 사용자 콘텐츠 증진과 사회적 인터렉션의 증진의 목적으로 인터렉티브 공공디스플레이가 제안되며 초기 단계로서 프로토타입 모델을 통한 사용자 관찰이 진행된다. 특히 사용자가 선호하는 정보입력 방법에 대한 설문과 비디오 분석이 실시되며 이를 통하여 사용자 행동 및 사용성 문제 등을 이해할 수 있으며 분석된 결과들은 다음 디자인 단계에 적용된다. With developments of technologies for large-scale digital display, public displays are being placed in public spaces such as subway stations, shopping malls, and universities. The displays are becoming a medium for social communication among people in the public place and are more engaging for the people while the tradition public displays were one-way dissemination of information. In this paper, we propose an interactive public display in a public space as a vehicle to encourage user participation, social interaction and creation of user content. The paper will present user studies carried out with a prototype model to establish how onsite users use it, their preferred ways to participation. The results of the user studies will inform the design of the interactive public display and provide learning point for the next stage.

      • SCIESCOPUS

        The use of limestone to replace physical filler of quartz powder in UHPFRC

        Kang, Sung-Hoon,Jeong, Yeonung,Tan, Kiang Hwee,Moon, Juhyuk Elsevier 2018 CEMENT AND CONCRETE COMPOSITES Vol.94 No.-

        <P><B>Abstract</B></P> <P>One of the key features of ultra-high performance fiber-reinforced concrete (UHPFRC) is the inclusion of quartz powder (QP) as a filler to optimize granular packing. However, QP has not been compared against limestone powder (LP) in terms of the filler effects, although it can affect hydration characteristics, strength development, and autogenous shrinkage of the concrete. In this study, the effectiveness of LP as a filler is evaluated against that of QP in order to verify its potential for use as a functional and human-friendly filler in UHPFRC. For this purpose, five types of fillers consisting of similar-sized QP and LP were designed while maintaining the same water-to-cement (w/c) and superplasticizer-to-cement (sppl/c) ratios. The early age strength increased by up to 12% depending on the LP content, due to the filler effect which accelerates cement hydration by providing a preferential surface for nucleation. Although the 28-day strength was 4%–7% lower than that of the classical UHPFRC containing QP, the 91-day strength was 1%–4% higher. The early age shrinkage was also accelerated by the filler effect of the LP, but its duration was shortened in proportion to the LP content.</P>

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