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RISS 인기검색어
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- 저자 : Kang. Taeuk (검색결과 41 건)
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( Taeuk Kang ),( Yoohyun Hwang ),( Jiyeon Kim ),( Jihee Jung ),( Dagyum Lee ),( Sungweon Ryoo ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-
Purpose Tuberculosis (TB) remains as a serious public health burden in Korea due to ease transmission. Mycobacterial Interspersed Repetitive Unit-Variable Number Tandem Repeat (MIRU-VNTR) is preferred for epidemiological TB investigation. However, the MIRU-VNTR has issues that MIRU-VNTR kit by GenoScreen (GeMIRU) is hard to be procured in Korea hence the difficulty lies epidemiological TB investigation/research. Here, we have comparatively analyzed the MIRU-VNTR kit by Kogene (KoMIRU). Method The 200 DNA samples, where 100 samples were clinical M. tuberculosis DNA samples from Masan National Tuberculosis Hospital and other 100 samples were non-M. tuberculosis, were used. Then, 200 samples were typed using KoMIRU and GeMIRU and compared for comparative analysis. KoMIRU and GeMIRU were done using the protocols provided by each manufacturer’s manual. Lineage strains were identified using MIRU-VNTRplus database (https://www.miru-vntrplus.org/MIRU/ index.faces) Result Of 200 samples, all clinical M. tuberculosis samples were amplified while non-M. tuberculosis samples were not, showing 100% for both sensitivity and specificity with 95% Confidence of Interval value of 96.38 - 100.00% (Table 1). KoMIRU typing kit has shown successful differentiation of M. tuberculosis from non-M. tuberculosis species. Also, no discrepancies observed on determined lineage strains between KoMIRU and GeMIRU. Out of 100, 84 were identified as Beijing strains and remainings were identified as NEW-1 (n=8), Uganda (n=6), EAI (n=6), Turkey (n=2), and Harleem (n=1) (Figure 1). Interestingly, among those non-Beijing strains except EAI, they are geographically distant lineage strains, Uganda, Turkey, and Harleem, and relatively unique strain, NEW-1. Conclusion The effectiveness of preventive TB intervention using GeMIRU has been globally proved. In this study, KoMIRU has shown comparable capability as GeMIRU and localization of MIRU-VNTR by Kogene is expected to allow efficient TB investigation in Korea. Also, previous researches had suggested association between lineage strains and drug resistance hence, this can be applied to initial TB treatment.
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( Taeuk Kang ),( Yoohyun Hwang ),( Jiyeon Kim ),( Jihee Jung ),( Dagyum Lee ),( Sungweon Ryoo ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-
Purpose Tuberculosis (TB) remains as public health burden in Korea. Beijing strain of Mycobacterium tuberculosis (M. tuberculosis) is assumed to be associated with hypervirulence and multi-drug resistance hence detection of such strain helps rapid detection of drug resistance. Thus, identification of Beijing strain is highly significant, in epidemiological and clinical aspects. Here, we present evaluation of the Real-time PCR kit for Beijing strain of Mycobacterium tuberculosis diagnostic® (KOGENE, Korea) (KOGENE RT-PCR) Method The 200 DNA samples, where 100 were clinical M. tuberculosis from Masan National Tuberculosis Hospital and other 100 were non-M. tuberculosis, were used. Strains of 100 M. tuberculosis were identified using MIRU-VNTR typing kit® (GenoScreen, France) and MIRU-VNTRplus database (URL: https://www.miru-vntrplus.org/MIRU/index.faces). Based on MIRU-VNTR result, the 84 out of 100 samples are identified as Beijing strain and remaining 16 samples are identified as non-Beijing strains. The KOGENE RT-PCR was conducted according to the manufacturer’s manual. Amplification of VIC fluorescence indicates M. tuberculosis-positive and amplification of both VIC and FAM fluorescences indicates Beijing strain of M. tuberculosis-positive. Result Of 200 samples, only 100 M. tuberculosis samples were amplified for VIC, showing 100% for both sensitivity and specificity with 95% Confidence of Interval (CI) value of 96.38-100%. Out of 100 M. tuberculosis, 84 Beijing strain of M. tuberculosis were positive for FAM, indicating 100% for both sensitivity and specificity with 95% CI values of 95.70-100% and 96.87-100% respectively (Table 1). Conclusion The clinical implication of Beijing strain is widely known. Here, investigated RT-PCR has shown capability in Beijing strain identification. Application of this tool could contribute in M. tuberculosis identification and prediction of possible drug resistance during pre- and initial treatment. Also, several outbreaks have been occurred by M. tuberculosis with Beijing strain. Hence, early identification of such strain is considered as highly useful in epidemiological TB investigation.
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( Taeuk Kang ),( Seungkyu Park ),( Sungweon Ryoo ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-
Background Tuberculosis still remains as intermediate-burden in Korea (Figure 1). For tuberculosis elimination, tuberculosis training/ education play pivotal role. Researches have suggested that provision of appropriate training/education could improve clinical outcome and prevent TB transmission. Despite significant role of TB training/education, TB training/education were poorly investigated. To assess current TB training/education program, identifying current status of TB training/education is inevitable. Hence, in this study, we reviewed articles and programs related to TB training/education in Korea and analyzed. Method A comprehensive review of literature on electronic databases and websites of TB-training providing organizations from year of 1995 to 2021 were undertaken. Result Several organizations from governmental/public sectors such as Korea Disease Control and Prevention Agency (KDCA), Korea National Tuberculosis Association (KNTA), Masan National Tuberculosis Hospital (MNTH), Korea Human Resource Development Institute for Health and Welfare (KOHI), Korea Nurses Association (KNA) were involved in provision of TB training/education. The KDCA conducts activities related to TB control and prevention at national, provincial, and local levels while KNTA, as commissioned by KDCA, provides TB trainings for healthcare workers with collaboration with KNA. In case of MNTH, this medical institute produced 14 TB medical specialists since 1993 and actively engaged in TB education at community level that 67,426 people were educated for TB prevention. Lastly, KOHI institutes provides several TB training/education programs for healthcare workers, medical technologists, and public (Table 1). Conclusion Although sufficient number of TB training/education are being provided. Its quality has never been assessed hence, there is difficulty lies in improvement of TB training/education due to lacking evaluation. Also, due to changing landscape of TB, training/education topics should reflect upcoming demands and be diversified such as inclusion of latent TB, drug-resistant TB and/or HIV/TB. The MNTH, with demonstrated history, is able to meet current demands from TB training/education.
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단기 홍수 지침 곡선을 이용한 남강대의 홍수조절에 관한 연구
Taeuk Kang,Sangjin Lee,Choi 위기관리 이론과 실천 2014 Crisisonomy Vol.10 No.12
남강댐의 상류유역은 산악지형이 대부분이기 때문에 하상경사가 매우 급하고, 홍수 시 유량이 급격히 증가한 다. 또한, 유역면적에 비해 홍수조절 용량이 매우 작고, 상․하류의 제약으로 인해 남강댐 운영자는 해마다 홍수 시 댐 운영에 어려움을 겪고 있다. 본 연구의 목적은 남강댐의 홍수 시 효과적인 댐 운영을 위해 단기 홍수 지침 곡선을 제시하는데 있다. 이를 위해 과거 남강댐에서 발생한 14개의 주요 홍수사상을 분석하였고, 수문학적 홍수 추적 모형인 COSFIM을 이용하여 과거 주요 홍수사상을 모의하였다. 단기 홍수 지침 곡선은 홍수 지침 곡선의 적용 시점과 홍수 진행에 따른 지침 수위와 운영 구간을 추정함으로써 결정되었다. 본 연구에서 제시한 홍수 지 침 곡선은 남강댐 홍수조절에 효과적으로 활용될 수 있을 것으로 기대한다. Upstream area of Namgang Dam is mountainous and has steep channel bed slopes, so the flood hydrograph from a storm rises rapidly. Namgang Dam operators have difficulties in flood control every year because the dam has small flood control capacity for catchment area and there are some restrictions on upstream and downstream of Namgang Dam to store or release water. The purpose of the study is to propose a flood guide curve in flood event of Namgang Dam for effective flood control. We analyzed major historical 14 flood events and simulated them by the COSFIM(Coordinate Operation System for Flood control In Multi-reservoir) that is hydrological flood routing model. The flood guide curve of Namgang Dam was determined by estimating application time of the flood guide curve and operation guide stages & ranges in process of flood time. The flood guide curve may be effectively used in flood control of Namgang Dam.
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디지털 필터 기반 기저유출 분리 기법의 특성 및 적용성 검토
강태욱(Taeuk Kang),이남주(Namjoo Lee) 한국방재학회 2022 한국방재학회논문집 Vol.22 No.3
디지털 필터 기반의 기저유출 분리 기법은 하천유량으로부터 기저유량을 분리하는 기법으로서 적절한 분석을 위해서는 필터 매개변수에 대한 추정이 요구된다. 이 연구에서는 4개의 디지털 필터 기반의 기저유출 분리 기법(Lyne-Hollick, Chapman, Eckhardt, EWMA)에 대하여 필터 매개변수 변화에 따른 분석 특성을 검토하였고, 적용성을 평가하였다. 각각의 디지털 필터 기법은 낙동강 지류 하천 중 5년간 연속된 유량측정 기록이 존재하는 대리 및 청송 수위관측소에 대하여 적용하였다. 기법별 적용성 평가 결과, Chapman 기법은 건기 시 기저유출 분리에 오류가 존재하는 것으로 나타났고, EWMA 기법은 기존 연구들에서 사용한 매개변수 범위 내에서 적절한 분석이 되지 않음을 확인하였다. Lyne-Hollick 기법과 Eckhardt 기법은 모두 필터 매개변수의 탐색 범위 내에서 적절한 결과를 도출할 수 있는 것으로 분석되었다. 다만, Eckhardt 기법은 상대적으로 필터 매개변수 변화에 따른 분석 결과의 변동이 크기 때문에 매개변수 결정에 신중을 기할 필요가 있는 것으로 판단되었다. Baseflow separation method based on the digital filter is a technique for separating the baseflow from the total streamflow, and appropriate estimation of the filter parameter is required for analysis. In this study, we reviewed the analysis characteristics of the four baseflow separation methods (Lyne-Hollick, Chapman, Eckhardt, and EWMA (exponentially weighted moving average)) based on the digital filter according to the change in the filter parameter and evaluated their applicability. Each digital filter method was applied to Daeri and Cheonsong stage stations, which have measurement records for five consecutive years for tributaries located of the Nakdonggang River in the Republic of Korea. The Chapman method had an error in the baseflow separation during the dry season. The EWMA method was not appropriately analyzed within the parameter range used in previous studies. The Lyne-Hollick and Eckhardt methods provided appropriate results within the exploring range of the filter parameter. However, in the Eckhardt method, we had to be careful in determining the filter parameter because the variation in analysis results was relatively large according to the parameter change.
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측정자료 기반의 유사 수지 분석과 하천 측량에 의한 하상 변동량의 비교 : 금강 일부 구간에 대한 사례 적용
강태욱(Kang, Taeuk),진영규(Jin, Youngkyu),서효원(Seo, Hyowon),이남주(Lee, Namjoo),김창성(Kim, Chang-Sung) 한국방재학회 2021 한국방재학회논문집 Vol.21 No.6
하천의 유사량 측정자료는 다양한 하천 계획과 연구에 기초자료로 활용된다. 이 연구에서는 다년간의 하천 단면 측량 결과와 유사량 측정자료 기반의 유사 수지 분석 결과로 산정된 하상 변동량을 비교⋅검토하였다. 유사 수지 분석의 공간적 범위는 상⋅하류 경계 및 지류 하천에서 유량 및 유사량이 모두 측정된 금강의 공주시(금강교) 수위관측소부터 부여군(백제교) 수위관측소 구간이고, 시간적 범위는 2011년부터 2016년까지이다. 분석 결과, 분석 대상 구간에서는 6년간 2,430,243 ton의 유사가 퇴적되는 것으로 분석되었다. 한편, 대상 구간에 대하여 측량된 하천 지형을 이용하여 하상 변동량을 산정하였다. 그 결과, 저수위 기준의 퇴적량은 2,165,146 ton, 홍수위 기준의 퇴적량은 3,055,489 ton으로 분석되었다. 하천 측량 성과를 기준으로 볼 때, 조사된 하상 변동량과 유사 수지 분석 결과로 산정된 하상 변동량의 차이는 저수위와 홍수위 기준에서 각각 10.9%와 -25.7%로 분석되었다. Sediment measurement data are utilized as basic data for various river plans and research. The aim of this study is to compare between sediment budget analysis and riverbed monitoring results. The spatial range was from the Gongju-si (Gemganggyo) station to the Buyeo-gun (Baekjegyo) station in Geumgang, and the temporal range in this study was from 2011 to 2016. The estimated change in riverbed amount using the sediment budget analysis was 2,430,243 tons for sediments loaded over six years in the section. The analyzed riverbed changes sedimentation using the riverbed monitoring method were 2,165,146 tons based on the low level and 3,055,489 tons based on the flood level. Based on the riverbed monitoring performance, the relative errors in the sediment budget analysis results through sediment measurements were 10.9% and -25.7% for the low water and flood levels, respectively.
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