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( Junfeng Lu ),( Xiaoxiao Wang ),( Yunxia Zhu ),( Lina Ma ),( Sujun Zheng ),( Zhongjie Hu ),( Xinyue Chen ) 대한간학회 2021 Gut and Liver Vol.15 No.6
Background/Aims: To investigate postpartum hepatic flares and associated factors in highly viremic pregnant patients in the immune tolerance phase who adopted telbivudine (LdT) treatment in the last trimester to reduce vertical transmission of hepatitis B virus. Methods: Hepatitis B e antigen (HBeAg)-positive, highly viremic pregnant women were recruited for this prospective study. Treatment with LdT was started from 28 weeks of gestation. Virological and biochemical markers were examined before LdT treatment, antepartum and postpartum. Serial blood samples at the same time were collected to detect cytokines and cortisol (COR). Results: Fifty-six of 153 patients (36.6%) had postpartum hepatic flares, defined as a 2-fold increase in alanine aminotransferase 6 weeks after delivery. Age and the antepartum alanine aminotransferase and postpartum HBeAg levels were independent influencing factors of postpartum hepatic flares. Cytokines showed no regularity during or after pregnancy. Compared with the patients with no postpartum flares, the patients with flares had lower baseline interferon γ and COR levels (p=0.022 and p=0.028) and higher postpartum interferon γ levels (p=0.026). Conclusions: A high proportion of highly viremic and immune-tolerant pregnant patients treated with LdT in the last trimester had postpartum hepatic flares, which implied that these patients entered the immune clearance phase after delivery. Thus, this may create an appropriate opportunity for re-antiviral therapy. (Gut Liver 2021;15:887-894)
Entire Functions That Share One Value With Their Derivatives
Lu, Feng,Xu, Junfeng Department of Mathematics 2007 Kyungpook mathematical journal Vol.47 No.3
In the paper, we use the theory of normal family to study the problem on entire function that share a finite non-zero value with their derivatives and prove a uniqueness theorem which improve the result of J.P. Wang and H.X. Yi.
Junfeng Wang,Milton R. Sommerfeld,Congming Lu,Qiang Hu 한국조류학회I 2013 ALGAE Vol.28 No.2
Nitrogen availability and cell density each affects growth and cellular astaxanthin content of Haematococcus pluvialis, but possible combined effects of these two factors on the content and productivity of astaxanthin, especially under outdoor culture conditions, is less understood. In this study, the effects of the initial biomass densities IBDs of 0.1, 0.5, 0.8, 1.5, 2.7, 3.5, and 5.0 g L-1 DW and initial nitrogen concentrations of 0, 4.4, 8.8, and 17.6 mM nitrate on growth and cellular astaxanthin content of H. pluvialis Flotow K-0084 were investigated in outdoor glass column photobioreactors in a batch culture mode. A low IBD of 0.1 g L-1 DW led to photo-bleaching of the culture within 1-2 days. When the IBD was 0.5 g L-1 and above, the rate at which the increase in biomass density and the astaxanthin content on a per cell basis was higher at lower IBD. When the IBD was optimal (i.e., 0.8 g L-1), the maximum astaxanthin content of 3.8% of DW was obtained in the absence of nitrogen, whereas the maximum astaxanthin productivity of 16.0 mg L-1 d-1 was obtained in the same IBD culture containing 4.4 mM nitrogen. The strategies for achieving maximum Haematococcus biomass productivity and for maximum cellular astaxanthin content are discussed.
Wang, Junfeng,Sommerfeld, Milton R.,Lu, Congming,Hu, Qiang The Korean Society of Phycology 2013 ALGAE Vol.28 No.2
Nitrogen availability and cell density each affects growth and cellular astaxanthin content of Haematococcus pluvialis, but possible combined effects of these two factors on the content and productivity of astaxanthin, especially under outdoor culture conditions, is less understood. In this study, the effects of the initial biomass densities IBDs of 0.1, 0.5, 0.8, 1.5, 2.7, 3.5, and 5.0 g $L^{-1}$ DW and initial nitrogen concentrations of 0, 4.4, 8.8, and 17.6 mM nitrate on growth and cellular astaxanthin content of H. pluvialis Flotow K-0084 were investigated in outdoor glass column photobioreactors in a batch culture mode. A low IBD of 0.1 g $L^{-1}$ DW led to photo-bleaching of the culture within 1-2 days. When the IBD was 0.5 g $L^{-1}$ and above, the rate at which the increase in biomass density and the astaxanthin content on a per cell basis was higher at lower IBD. When the IBD was optimal (i.e., 0.8 g $L^{-1}$), the maximum astaxanthin content of 3.8% of DW was obtained in the absence of nitrogen, whereas the maximum astaxanthin productivity of 16.0 mg $L^{-1}\;d^{-1}$ was obtained in the same IBD culture containing 4.4 mM nitrogen. The strategies for achieving maximum Haematococcus biomass productivity and for maximum cellular astaxanthin content are discussed.
Distinct Electronic Structure for the Extreme Magnetoresistance in YSb
He, Junfeng,Zhang, Chaofan,Ghimire, Nirmal J.,Liang, Tian,Jia, Chunjing,Jiang, Juan,Tang, Shujie,Chen, Sudi,He, Yu,Mo, S.-K.,Hwang, C. C.,Hashimoto, M.,Lu, D. H.,Moritz, B.,Devereaux, T. P.,Chen, Y. L American Physical Society 2016 Physical Review Letters Vol.117 No.26
Chenchen Wang,Junfeng Zhou,Yunkun Zhao,Youze Chen,Benli Yu,Liang Lu 한국물리학회 2019 Current Applied Physics Vol.19 No.4
This paper proposed a new method for measuring the feedback coefficient in the self-mixing interference. In experiment, the value of feedback coefficient is obtained by measuring the power difference at power jump point that based on the self-mixing vibration sensing system. It realized the measurement of feedback coefficient in range of 1–7.8 and shows a good agreement with the theoretical derivation and the corresponding simulation. Meanwhile, there is a good fitting result with the determination coefficient of 0.98 and line-width broadening factor of 3.245 respectively, which also realized measurement of feedback coefficient and line-width broadening factor at the same time.
Nijiati Kudulaiti,Tianming Qiu,Junfeng Lu,Huiwei Zhang,Zhengwei Zhang,Yihui Guan,Dongxiao Zhuang,Jinsong Wu 대한영상의학회 2019 Korean Journal of Radiology Vol.20 No.6
Objective: To evaluate whether the combination of magnetic resonance spectroscopy (MRS) and 11C-methionine positron emission tomography (11C-MET PET) could increase accurate diagnostic sensitivity for non-enhancing supratentorial gliomas. Materials and Methods: Between February 2012 and December 2017, 109 patients with non-enhanced supratentorial lesions on contrast-enhanced MRI were enrolled. Each patient underwent MRS and 11C-MET PET before treatment. A lesion was considered to be a glioma when either the MRS or 11C-MET PET results reached the diagnostic threshold. The radiological diagnosis was compared with the pathological diagnosis or medical diagnostic criteria. Results: The sensitivity and specificity were 60.0% and 50.0% for MRS and 75.8% and 50.0% for 11C-MET PET, respectively. Upon combining the two modalities, the sensitivity and specificity of the imaging-based diagnosis prior to surgery reached 89.5% and 42.9%, respectively. Statistically significant differences in the sensitivities were observed between the combined and individual approaches (MRS alone, 89.5% vs. 60.0%, p < 0.001; 11C-MET PET alone, 89.5% vs. 75.8%, p = 0.001). However, no significant differences in specificity were observed between the combined and individual modalities. Conclusion: The combination of MRS and 11C-MET PET findings significantly increases accurate diagnostic sensitivity for nonenhancing supratentorial gliomas without significantly lowering the specificity. This finding suggests the potential of the combined MRS and 11C-MET PET approach in clinical applications.