Semantic Web Service Discovery Algorithm based on Constraint Extraction and Structure Analysis

Kun Li,Huayu Li,Jidong Chen 보안공학연구지원센터 2016 International Journal of u- and e- Service, Scienc Vol.9 No.4

As the Internet Web services increased, how to find a web service which can meet user's requirements quickly and accurately has become a problem to be solved .Now many kinds of web service methods based on semantic are based IO matching .They used other ways to supplement while semantic matching is failed. However the accuracy of semantic web service discovery based on IO matching purely is not high enough, the Algorithm of semantic web service discovery which is based on constraint extraction and structure analysis is proposed. It is divided into two parts. First part is to carry out the concept of semantic matching based on constraint extraction .Then it uses algorithm based on structure analysis while matching is failed, aiming to assess the structural similarity of the desired vs the retrieved services and the semantic similarity of their identifiers. This article uses owls-tc2.0 as test set to test this method .The experimental results show that this method improves service discovery accuracy effectively.

Random vibration fatigue life assessment and optimization of a train buffer beam considering welding residual stress

Chengji Mi,Jidong Liu,Xuewen Xiao,Wentai Li,Xiao Sun,Xingzu Ming,Changyan Tao,Ziyi Ren 대한기계학회 2020 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.34 No.3

The traditional fatigue design of accessories attached to a train body does not consider welding residual stress for fatigue life prediction of welded structures during the design stage, thereby resulting in insufficient fatigue strength for local welded parts. The power spectral density of random excitation caused by rail irregularity from American six-level spectrums was obtained in this paper. Through welding thermal elastoplastic theory combined with ellipsoid heat source model, a numerical simulation for welding residual stress production and distribution of a train buffer beam was conducted. In accordance with the coupling stress component, the fatigue performance of a train buffer beam under random loads was evaluated by the AA6082 welded joint S–N curve, whose lifetime did not satisfy design requirements. Then, the surrogate model of a train buffer beam for anti-fatigue optimization design was constructed based on the response surface method. The fatigue life of the optimized train buffer beam increased by two orders with the use of the genetic algorithm to find the optimal solution in global variables.

New constructive model for structures soil

Zhang, Sheng,Li, Haichao,Teng, Jidong Techno-Press 2016 Geomechanics & engineering Vol.11 No.5

A theoretical study of the behavior of structured soils is presented herein. By introducing the effect of soil structure and loading history into the Cam Clay model, a new model was formulated. The concept of differing void ratios was modified to combine structural parameters and the over consolidation ratio, and an evolution law was proposed. Upon introducing the concept of the subloading yield surface, a new two-yield surface model was obtained. The predicted results were compared to the experimental data, demonstrating that the new model provided satisfactory qualitative modeling of many important features of structured soils.

Mechanism of Tungsten Recovery from Spent Cemented Carbide by Molten Salt Electrodeposition

Hongxuan Xing,Zhen Li,Enrui Feng,Xiaomin Wang,Hongguang Kang,Yiyong Wang,Hui Jin,Jidong Li The Korean Electrochemical Society 2023 Journal of electrochemical science and technology Vol.14 No.1

The accumulation of spent carbide (YG8), not only pollutes the environment but also causes waste of tungsten, cobalt and other rare metal resources. To better address this issue, we proposed a combined electrochemical separation process of low-temperature aqueous solution and high-temperature molten salt for tungsten and cobalt. H₂WO₄ was obtained from spent carbide in an aqueous solution, and we calcined it to obtain WO₃, which was used as a raw material to obtain tungsten by using molten salt electrodeposition. The influence of the current efficiency and the electrochemical behavior of the discharge precipitation of W(VI) were also studied. The calcination results showed that the morphology of WO₃ was regular and there were no other impurities. The maximum current efficiency of 82.91% was achieved in a series of electrodeposition experiments. According to XRD and SEM analysis, the recovered product was high purity tungsten, which belongs to the simple cubic crystal system. In the W(VI) reduction mechanism experiments, the electrochemical process of W(VI) in NaCl-Na₂WO₄-WO₃ molten salt was investigated using linear scanning voltammetry (LSV) and chronoamperometry in a three-electrode system. The LSV showed that W(VI) was reduced at the cathode in two steps and the electrode reaction was controlled by diffusion. The fitting results of chronoamperometry showed that the nucleation mechanism of W(VI) was an instantaneous nucleation mode, and the diffusion coefficient was 7.379×10^-10 cm²·s^-1.

Postoperative circulating tumor DNA detection and CBLB mutations are prognostic biomarkers for gastric cancer

Zhou Hekai,Liu Houcong,Li Jun,Wang Jidong,Fu Xiaohong,Li Yingqiang,Mao Shaolong,Du Jihui 한국유전학회 2023 Genes & Genomics Vol.45 No.8

Background Several studies have demonstrated that circulating tumor DNA (ctDNA) can be used to predict the postoperative recurrence of several cancers. However, there are few studies on the use of ctDNA as a prognosis tool for gastric cancer (GC) patients. Objective This study aims to determine whether ctDNA could be used as a prognostic biomarker in GC patients through multigene-panel sequencing. Methods Using next-generation sequencing (NGS) Multigene Panels, the mutational signatures associated with the prognosis of GC patients were identified. We calculated the survival probability with Kaplan–Meier and used the Log-rank test to compare survival curves between ctDNA-positive and ctDNA-negative groups. Potential application of radiology combined with tumor plasma biomarker analysis of ctDNA in GC patients was carried out. Results Disease progression is more likely in ctDNA-positive patients as characterized clinically by a generally higher T stage and a poorer therapeutic response (P < 0.05). ctDNA-positive patients also had worse overall-survival (OS: P = 0.203) and progression-free survival (PFS: P = 0.037). The combined analysis of ctDNA, radiological, and serum biomarkers in four patients indicated that ctDNA monitoring can be a good complement to radiological and plasma tumor markers for GC patients. Kaplan–Meier analysis using a cohort of GC patients in the TCGA database showed that patients with CBLB mutations had shorter OS and PFS than wild-type patients (OS: P = 0.0036; PFS: P = 0.0027). Conclusions This study confirmed the utility and feasibility of ctDNA in the prognosis monitoring of gastric cancer.

Complete Mitochondrial Genome Sequences of Chinese Indigenous Sheep with Different Tail Types and an Analysis of Phylogenetic Evolution in Domestic Sheep

Fan, Hongying,Zhao, Fuping,Zhu, Caiye,Li, Fadi,Liu, Jidong,Zhang, Li,Wei, Caihong,Du, Lixin Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.5

China has a long history of sheep (Ovis aries [O. aries]) breeding and an abundance of sheep genetic resources. Knowledge of the complete O. aries mitogenome should facilitate the study of the evolutionary history of the species. Therefore, the complete mitogenome of O. aries was sequenced and annotated. In order to characterize the mitogenomes of 3 Chinese sheep breeds (Altay sheep [AL], Shandong large-tailed sheep [SD], and small-tailed Hulun Buir sheep [sHL]), 19 sets of primers were employed to amplify contiguous, overlapping segments of the complete mitochondrial DNA (mtDNA) sequence of each breed. The sizes of the complete mitochondrial genomes of the sHL, AL, and SD breeds were 16,617 bp, 16,613 bp, and 16,613 bp, respectively. The mitochondrial genomes were deposited in the GenBank database with accession numbers KP702285 (AL sheep), KP981378 (SD sheep), and KP981380 (sHL sheep) respectively. The organization of the 3 analyzed sheep mitochondrial genomes was similar, with each consisting of 22 tRNA genes, 2 rRNA genes (12S rRNA and 16S rRNA), 13 protein-coding genes, and 1 control region (D-loop). The NADH dehydrogenase subunit 6 (ND6) and 8 tRNA genes were encoded on the light strand, whereas the rest of the mitochondrial genes were encoded on the heavy strand. The nucleotide skewness of the coding strands of the 3 analyzed mitogenomes was biased toward A and T. We constructed a phylogenetic tree using the complete mitogenomes of each type of sheep to allow us to understand the genetic relationships between Chinese breeds of O. aries and those developed and utilized in other countries. Our findings provide important information regarding the O. aries mitogenome and the evolutionary history of O. aries inside and outside China. In addition, our results provide a foundation for further exploration of the taxonomic status of O. aries.

Anatomical Observations of Adventitious Bud Regeneration from Leaf Explants of Ziziphus jujube Mill. ‘Huizao’

Chunhua Ma,Xia Ye,Yanhui Chen,Jiancan Feng,Xiaoli Shang,Jidong Li,Yingxia Wu,Jianbin Hu 한국원예학회 2012 Horticulture, Environment, and Biotechnology Vol.53 No.4

The histological process of adventitious shoot regeneration from the leaf explants of Zizyphus jujuba ‘Huizao’was reported in this study. This is the first report on the detailed histological process of direct shoot regeneration from leaf explants in Z. jujube. Shoot regeneration was obtained from woody plant medium (WPM) supplemented with 2.27 μM thidiazuron (TDZ), 1.07 μM α-naphthalene-acetic acid (NAA) and 2.94 μM silver nitrate (AgNO3) for 10days in the dark followed by 3 weeks at a 14 hours photoperiod. The adventitious buds mostly formed from leaf veins and petioles, and the further histological studies revealed that there were multiple vascular bundles around leaf veins and the adaxial side of explants, and the adventitious buds directly originated from the parenchymatous cells around the vascular bundles without the intervening callus phase. After 3 days of culture, the parenchymatous cells started dividing and meristemoids formed thereafter. The meristematic cells continued division and subsequently gave rise to bud primordia. Well-developed shoot buds through direct organogenesis was achieved after 20 days of culture.

Efficacy and Safety of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir in Non-Cirrhotic Asian Patients with Genotype 1b HCV Infection: ONYX-I SVR24 Results

( Lai Wei ),( Jinlin Hou ),( Yan Luo ),( Jeong Heo ),( Chi-jen Chu ),( Zhongping Duan ),( Mong Cho ),( Jun Cheng ),( Jun Li ),( Jidong Jia ),( Wenjing Lu ),( Linda M Fredrick ),( Tami Pilot-matias ),( 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

Aims: HCV genotype 1b is the most common genotype in Asian patients. ONYX-I is a phase 3, randomised, double-blind, placebo-controlled study of the 3-DAA regimen of OBV/PTV/r and DSV in treatment- naive and treatment-experienced non-cirrhotic patients with HCV GT1b infection in China, South Korea and Taiwan. Methods: In this study, the safety/efficacy of OBV/PTV/r + DSV administered for 12 weeks were evaluated in non-cirrhotic Asian patients. Patients in Arm A received active study drug during a 12-week double-blind (DB) period, while patients in Arm B received placebo during the same period followed by an open-label (OL) period in which they received 12 weeks of active study drug. Efficacy was assessed by SVR12 and SVR24. Efficacy and safety were assessed in all patients who received at least one dose of active study drugs. Results: 650 HCV GT1b patients (54% female, 100% Asian, 44% treatment-experienced) were enrolled from China (n=410) South Korea (n=120) and Taiwan (n=120), and randomised 1:1 to Arms A and B. In Arm A, SVR12 and SVR24 rates were 99.5% (183/184) in treatment-naive patients and 100% (141/141) in treatment- experienced patients. Most treatment-emergent adverse events (TEAEs) in patients receiving the active drug were mild in severity. The most common (≥5%) TEAEs in Arm A were upper respiratory tract infection (10.5%), headache (6.2%) and dizziness (5.2%). Seven patients had serious AEs during active treatment (Arm A) and one patient in Arm A discontinued treatment. Conclusions: In non-cirrhotic Asian adults with HCV GT1b-infection, treated with OBV/PTV/r + DSV for 12 weeks, SVR24 rates equalled previously reported SVR12 rates from this study (99.5% of treatment- naive and 100% of treatment-experienced patients), and are consistent with other clinical trials with this drug combination. The treatment was generally well tolerated with mostly mild TEAEs reported.

MACC1 Expression Correlates with PFKFB2 and Survival in Hepatocellular Carcinoma

Ji, Dong,Lu, Zhong-Tang,Li, Yao-Qing,Liang, Zhe-Yong,Zhang, Peng-Fei,Li, Chao,Zhang, Jun-Li,Zheng, Xin,Yao, Ying-Min Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2

Objective: To validate the relationship between MACC1 and 6-phosphofructo-2-kinase/fructose 2, 6 bisphosphatase (PFKFB2) expression as well as its clinicopathological features and prognostic significance in hepatocellular carcinoma. Methods: By using immunohistochemistry, we investigated the MACC1 and PFKFB2 protein expression in 60 pairs of hepatocellular carcinoma and corresponding non-tumor tissues. Using the Mann-Whitney U test, the Chi-square test, Kaplan-Meier survival analysis, Cox proportional hazard regression analysis and Spearman analysis, we studied the relationship between MACC1 and PFKFB2 protein expression and postoperative overall survival (OS) of the HCC patients. Results: MACC1 and PFKFB2 positive staining rates were significantly higher in hepatocellular carcinoma than in the corresponding nontumor tissues (P=0.012 and 0.04, respectively). The clinicopathological features evaluation revealed that positive expression of MACC1 was associated with a high Edmondson classification (P=0.007) and advanced TNM stage (P=0.027). Similar findings were evident for PFKFB2 expression (P=0.002 and P=0.027). MACC1 and PFKFB2 positive expression was associated with a lower OS rate (P=0.004 and 0.03, respectively). Kaplan-Meier survival and Cox proportional hazard regression analyses revealed MACC1 positive expression to be a prognostic factor for postoperative OS, but PFKFB was not. Conclusion: Highly expressed MACC1 and PFKFB2 protein were associated with TNM stage, Edmondson-Steier classification and overall survival. MACC1 may affect tumor metabolism partly through expression and phophorylation of PFKFB2.