Effect of horizontal joints on structural behavior of sustainable self-compacting reinforced concrete beams

Ibrahim, Omar Mohamed Omar,Heniegal, Ashraf Mohamed,Ibrahim, Khamis Gamal,Agwa, Ibrahim Saad Techno-Press 2020 Advances in concrete construction Vol.10 No.5

This study investigated the effect of horizontal casting joints on the mechanical properties and structural behavior of sustainable self-compacting reinforced concrete beams (SCRCB). The experimental research consisted of two stages. The first stage used four types of concrete mixtures which were produced to indicate the effects of cement replaced with cement waste at 0%, 5%, 10%, and 15% by weight of cement content on fresh concrete properties of self-compacting concrete (SCC) such as, passing ability, filling ability, and segregation resistance. In addition, mechanical properties such as compressive, tensile, and flexural strength were also studied. The second stage selected the best mixture from the first stage and studied the effect of horizontal casting joints on the structural behavior of sustainable SCRCBs. The effect of horizontal casting joints on the mechanical properties and structural behavior were at the 25%, 50%, 75%, and 100% of sample height. Load deflection, failure mode, and theoretical analysis were studied. Results indicated that the incorporation of replacement with cement waste by 5% to 10% led to economic and environmental advantages, and the results were acceptable for fresh and mechanical properties. The results indicated that delaying the time for casting the second layer and increasing the cement waste in concrete mixtures had a great effect on the mechanical properties of SCC. The ultimate load capacity of horizontal casting joints reinforced concrete beams slightly decreased compared with the control beam. The maximum deflection of casting joint beams with 75% of samples height is similar with the control beam. The experimental results of reinforced concrete beams were substantially acceptable with the theoretical results. The failure modes obtained the best forced casting joint on the structural behavior at 50% height of casting in the beam.

A hypertension risk score for adults: a population-based cross-sectional study from Dubai Household Survey 2019

Mahmoud Ibrahim,Sulaiman Nabil,Hussein Amal,Mohammed Heba,AL Nakhi Wafa Khamis,Hussain Hamid,Ibrahim Gamal 한국역학회 2021 Epidemiology and Health Vol.43 No.-

OBJECTIVES: The aim of this study was to develop a risk score model for predicting hypertension specific to the population of Dubai in the United Arab Emirates (UAE) to facilitate prevention and early intervention. METHODS: A retrospective analysis of data from the Dubai Household Health Survey 2019 was conducted. Demographic and physical parameters, as well as blood glucose levels, were included in the data. The risk factors for hypertension were identified using bivariate analysis. A risk score model was developed using the enter method, where all significant predictors of hypertension in bivariate analyses were entered in a single step with the primary outcome of hypertension status (yes/no). The model was validated internally by splitting the data into Emirati and non-Emirati populations. RESULTS: A total of 2,533 subjects were studied. The significant risk factors for hypertension identified were male sex, older age (≥ 40 years), education level, body mass index, diabetes mellitus, and dyslipidaemia. The model showed a high discrimination ability between individuals with and without hypertension, with an area under the curve of 0.77 (95% confidence interval [CI], 0.75 to 0.79), excellent sensitivity (81.0%; 95% CI, 71.9 to 88.2) and moderate specificity (56.0%; 95% CI, 45.7 to 65.9). CONCLUSIONS: The model developed by this study is simple, convenient, and based on readily available demographic and medical characteristics. This risk score model could support initial hypertension screening and provide an effective tool for targeted lifestyle counselling and prevention programs.

New anti-inflammatory flavonoids from Cadaba glandulosa Forssk

Gamal A. Mohamed,Sabrin R. M. Ibrahim,Nawal M. Al-Musayeib,Samir A. Ross 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.4

Three new flavonoids; kaempferol-40-phenoxy-3,30,50-trimethylether (3), rhamnocitrin-40-(4-hydroxy-3-methoxy)phenoxy-3-methyl ether (4), and rhamnocitrin-3-O-neohesperoside-40-O-rhamnoside (6), along with threeknown compounds; 4-methoxy-benzyldehyde (1),kaempferol-3-methylether (2), and stachydrine (5) wereisolated from the aerial parts of Cadaba glandulosa Forssk. Their chemical structures were established by physical,chemical, and spectral methods, as well as comparison with literature data. The antioxidant and anti-inflammatoryactivities of the isolated compounds were determined. Compounds 2–4, and 6 exhibited potent anti-inflammatoryactivity comparable with indomethacin and moderateantioxidant activity.

Effect of Diazinon, an Organophosphate Insecticide, on Plasma Lipid Constituents in Experimental Animals

Ibrahim, Nagi A.,El-Gamal, Basiouny A. Korean Society for Biochemistry and Molecular Biol 2003 Journal of biochemistry and molecular biology Vol.36 No.5

There has been increasing interest in studying the various effects of organophosphate insecticides in humans and experimental animals. Only a few data are available on the effect of the organophosphate insecticide, diazinon, on lipid metabolism. The aim of this study was to evaluate the effect of diazinon on plasma lipid constituents in mammalian animals. The plasma levels of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), and phospholipids (PL) were measured in albino rats that were orally treated with a single dose of diazinon at a level of $LD_{50}$ or with repeated daily doses at the levels of $\frac{1}{2}$, $\frac{1}{8}$, and $\frac{1}{32}$ $LD_{50}$ for 2, 8, and 32 days, respectively. After a 24 h post-treatment with a single $LD_{50}$ dose of diazinon, TC was not significantly changed, the HDL-C and PL levels were significantly decreased, but the LDL-C and TG levels were significantly increased. Separate daily oral administrations of diazinon at $\frac{1}{2}$ $LD_{50}$, $\frac{1}{8}$ $LD_{50}$, and $\frac{1}{32}$ $LD_{50}$ doses resulted in a significant decrease in HDL-C and PL, with no significant change in TG. The LDL-C levels were significantly increased and TC showed no significant change with $\frac{1}{2}$ $LD_{50}$ and $\frac{1}{32}$$LD_{50}$ doses of diazinon, whereas a significant decrease in the levels of TC, HDL-C, as well as LDL-C, was observed with the $\frac{1}{8}$ $LD_{50}$ dose. These data suggest that diazinon may interfere with lipid metabolism in mammals.

New anti-inflammatory flavonoids from Cadaba glandulosa Forssk

Mohamed, Gamal A.,Ibrahim, Sabrin R.M.,Al-Musayeib, Nawal M.,Ross, Samir A. 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.4

Three new flavonoids; kaempferol-4'-phenoxy-3,3',5'-trimethylether (3), rhamnocitrin-4'-(4-hydroxy-3-methoxy)phenoxy-3-methyl ether (4), and rhamnocitrin-3-O-neohesperoside-4'-O-rhamnoside (6), along with three known compounds; 4-methoxy-benzyldehyde (1), kaempferol-3-methylether (2), and stachydrine (5) were isolated from the aerial parts of Cadaba glandulosa Forssk. Their chemical structures were established by physical, chemical, and spectral methods, as well as comparison with literature data. The antioxidant and anti-inflammatory activities of the isolated compounds were determined. Compounds 2-4, and 6 exhibited potent anti-inflammatory activity comparable with indomethacin and moderate antioxidant activity.

Effect of Diazinon, an Organophosphate Insecticide, on Plasma Lipid Constituents in Experimental Animals

( Nagi A. Ibrahim ),( Basiouny A. El Gamal ) 생화학분자생물학회 2003 BMB Reports Vol.36 No.5

There has been increasing interest in studying the various effects of organophosphate insecticides in humans and experimental animals. Only a few data are available on the effect of the organophosphate insecticide, diazinon, on lipid metabolism. The aim of this study was to evaluate the effect of diazinon on plasma lipid constituents in mammalian animals. The plasma levels of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), and phospholipids (PL) were measured in albino rats that were orally treated with a single dose of diazinon at a level of LD_(50) or with repeated daily doses at the levels of 1/2, 1/8, and 1/32 LD_(50) for 2, 8, and 32 days, respectively. After a 24 h post-treatment with a single LD,, dose of diazinon, TC was not significantly changed, the HDL-C and PL levels were significantly decreased, but the LDL-C and TG levels were significantly increased. Separate daily oral administrations of diazinon at 1/s LD_(50), 1/8 LD_(50), and 1/32 LD,, doses resulted in a significant decrease in HDL-C and PL, with no significant change in TG. The LDL-C levels were significantly increased and TC showed no significant change with 1/2 LD_(50) and 1/32 LD, doses of diazinon, whereas change with 1/2 LD_(50) and 1/32 LD, doses of diazinon, whereas a significant decrease in the levels of TC, HDL-C, as well as LDL-C, was observed with the 1/8 DL,, dose. These data suggest that diazinon may interfere with lipid metabolism in mammals.

Comparing automated and non-automated machine learning for autism spectrum disorders classification using facial images

Basma Ramdan Gamal Elshoky,Eman M. G. Younis,Abdelmgeid Amin Ali,Osman Ali Sadek Ibrahim 한국전자통신연구원 2022 ETRI Journal Vol.44 No.4

Autism spectrum disorder (ASD) is a developmental disorder associated with cognitive and neurobehavioral disorders. It affects the person’s behavior and performance. Autism affects verbal and non-verbal communication in social interactions. Early screening and diagnosis of ASD are essential and helpful for early educational planning and treatment, the provision of family support, and for providing appropriate medical support for the child on time. Thus, developing automated methods for diagnosing ASD is becoming an essential need. Herein, we investigate using various machine learning methods to build predictive models for diagnosing ASD in children using facial images. To achieve this, we used an autistic children dataset containing 2936 facial images of children with autism and typical children. In application, we used classical machine learning methods, such as support vector machine and random forest. In addition to using deep-learning methods, we used a state-of-the-art method, that is, automated machine learning (AutoML). We compared the results obtained from the existing techniques. Consequently, we obtained that AutoML achieved the highest performance of approximately 96% accuracy via the Hyperpot and tree-based pipeline optimization tool optimization. Furthermore, AutoML methods enabled us to easily find the best parameter settings without any human efforts for feature engineering.

Factors affecting in vitro embryo production: insights into dromedary camel

Adel R. Moawad,Ibrahim M. Ghoneim,Gamal M. Darwish,Magdy R. Badr,Diya A. El-Badry,Abou Bakr A. EL-Wishy 사단법인 한국동물생명공학회 2020 한국동물생명공학회지 Vol.35 No.2

The Dromedary camel (Camelus dromedaries) is an important species because of its ability to produce good quality meat, milk, and fibers under harsh environmental conditions. Camels are also crucial for transportation, racing, and as draft animals in agriculture. Therefore, dromedary camels play a critical role in the economy for millions of people living in the arid part of the world. The inherent capability of camels to produce meat and milk is highly correlated with their reproductive performance. Compared with other domestic species, the reproductive efficiency in camelids is low. Although recent reproductive technologies such as in vitro fertilization (IVF) and somatic cell nuclear transfer (SCNT) have been successfully applied to camelids and the birth of live offspring following these technologies has been reported; in vitro embryo production (IVP) has lagged in this species. The development of the IVP system for dromedary camels may be a useful tool for the genetic improvement of this species. IVP in farm animals includes three main steps; in vitro maturation (IVM) of an oocyte, IVF of a matured oocyte, and in vitro culture (IVC) of fertilized oocyte up to the blastocyst stage. This review aims to summarize various factors that influence oocyte quality, IVM, and in vitro embryo development in dromedary camel.

Biochemically Altered Human Erythrocytes as a Carrier for Targeted Delivery of Primaquine: an In Vitro Study

Fars K. Alanazi,Ibrahim A. Alsarra,Gamal El-Din I. Harisa,Ahmad Maqboul,Magdi Abdel-Hamid,Steven H. Neau 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.4

The aim of this study was to investigate human erythrocytes as a carrier for targeted drug delivery of primaquine (PQ). The process of PQ loading in human erythrocytes, as well as the effect of PQ loading on the oxidative status of erythrocytes, was also studied. At PQ concentrations of 2, 4, 6, and 8 mg/mL and an incubation time of 2 h, the ratios of the concentrations of PQ entrapped in erythrocytes to that in the incubation medium were 0.515, 0.688, 0.697 and 0.788, respectively. The maximal decline of erythrocyte reduced glutathione content was observed at 8 mg/mL of PQ compared with native erythrocytes p < 0.001. In contrast, malondialdehyde and protein carbonyl were significantly increased in cells loaded with PQ (p < 0.001). Furthermore, osmotic fragility of PQ carrier erythrocytes was increased in comparison with unloaded cells. Electron microscopy revealed spherocyte formation with PQ carrier erythrocytes. PQ-loaded cells showed sustained drug release over a 48 h period. Erythrocytes were loaded with PQ successfully, but there were some biochemical as well as physiological changes that resulted from the effect of PQ on the oxidative status of drugloaded erythrocytes. These changes may result in favorable targeting of PQ-loaded cells to reticulo-endothelial organs. The relative impact of these changes remains to be explored in ongoing animal studies.

Effect of genotype of growing rabbits on productive performance with special reference to residual feed intake at hot temperature

Moataz Fathi,Magdy Abdelsalam,Ibrahim Al-Homidan,Osama Abou-Emera,Gamal Rayan Asian Australasian Association of Animal Productio 2023 Animal Bioscience Vol.36 No.7

Objective: Better feed efficiency can be achieved by selecting rabbit genotypes with lower residual feed intake (RFI) under high ambient temperatures. Methods: Two genotypes of rabbits (Jabali, Saudi local breed and imported, Spanish V-line) were used to derive RFI and to investigate the relationship between RFI and productive traits. In total, 250 animals (125 each) were housed in individual wire mesh cages in a semi-closed rabbitry. Growth performance, feed criteria, carcass evaluation, biochemical blood analysis, and immune responses were determined. Results: Superiority in growth performance, feed efficiency, carcass characteristics, and cellular immunity was recorded in the Jabali breed compared to the V-line genotype. According to regression analysis, a significant effect of daily body weight gain was found, upon computing the expected feed intake in both genotypes. Moreover, mid-body weight^0.75 had a significant effect only in the Jabali breed. Positive correlation coefficients between RFI and dry matter feed intake or feed conversion ratio were found. The same trend in this relationship between RFI and productive traits was observed in some cases for both genotypes. An opposite trend in correlations was observed in the studied genotypes for some traits. Conclusion: The results suggest that the relationship between RFI and productive traits must be taken into consideration in rabbit breeding programs under the prevailing environment. However, further studies are required to investigate the effect of rabbit genotype and environmental factors on computing RFI.