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Laccaria laccata B.의 Phytohemoagglutinin에 關한 硏究
金亨會,文國鎭 고려대학교 의과대학 1973 고려대 의대 잡지 Vol.10 No.3
The author screened twenty three kinds of mushroom native to Korea on its hemoagglutination activity to human red blood cell (RBC) and found out a new Phytohelnoagglutinin (PHA) in the saline extract of Laccaria laccata B. (LLB). Its hemoagglutination titer, absorption test with human saliva and sugars, heat stability test, salt fractionation by anmonium sulfate, sperm agglutination activity and elution test were studied. The results could be summarized as follows : 1) Anti A-lectin was found in LLB. 2) Anti A-lectin in LLB was absorbed by same group's RBC and saliva of secretor. 3) The agglutination titer of anti A-lectin in LLB were 1:8 with type A RBC and 1:4 with type AB RBC, and its optimal temperature of agglutination was 37℃. 4) The anti A-lectin was found in precipitates of LLB treated by 40% saturated amiuonium sulfate solution. 5) The agglutinating activity of anti A-fraction in LLB was inhibited by various sugars except dextrose. 6) The human sperms were not agglutinated by PHA in LLB. 7) It was possible to detect blood type A RBC in the blood stains and various humoral stains by elution test with anti A-lectin in LLB.
( Hyung Koo Kang ),( Hye Yun Park ),( Do Hun Kim ),( Byeong Ho Jeong ),( Kyeong Man Jeon ),( Hong Kwan Kim ),( Yong Soo Choi ),( Jhin Gook Kim ),( Won Jung Koh ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Outcomes of antibiotic treatment for lung disease caused by nontuberculous mycobacteria (NTM) are unsatisfactory.Methods: We conducted a retrospective review of 70 patients who underwent pulmonary resection for NTM lung disease from March 2007 to February 2013. All patients received recommended antibiotic treatment before and after the surgery. Results: A total of 70 patients underwent 74 operations. The median age of the patients was 50 years (IQR, 43-58 years). Of the 70 patients, 45 (64%) had Mycobacterium avium complex infection (24 M. intracellulare and 21 M. avium), 23 (33%) had M. abscessus complex infection (15 M. abscessus and 8 M. massiliense), and two (3%) had mixed infection. Thirty-eight (54%) patients had the nodular bronchiectatic form and 28 (40%) had the fi brocavitary form of NTM lung disease. The indications for surgery were a poor response to drug therapy (n = 52), remnant cavitary lesions and severe bronchiectasis (n = 14), and hemoptysis (n = 4). Preoperative sputum acid-fast bacilli staining results were positive in 44 (63%) patients, and sputum culture was positive in 54 (76%). The surgery included lobectomy or lobectomy plus segmentectomy (n = 50, 68%), segmentectomy (n = 11, 15%), pneumonectomy or completion pneumonectomy (n = 8, 11%), bilobectomy or bilobectomy plus segmentectomy (n = 4, 5%), and one wedge resection. Postoperative complications occurred in 15 (21%) patients, including postoperative death (n = 1) and bronchopleural fi stula (n = 5). A negative sputum culture was achieved and maintained in 57 (81%) patients. Conclusions: Although adjuvant pulmonary resection is associated with a relatively high complication rate, this procedure could provide a high level of treatment success for selected patients with NTM lung disease, such as those with a poor response to antibiotic treatment alone
Association Between Oral Health and Airflow Limitation: Analysis Using a Nationwide Survey in Korea
Kim Sun-Hyung,Gu Seonhye,Kim Jung-Ae,Im YoHan,Cho Jun Yeun,Kim Youlim,Shin Yoon Mi,Kim Eung-Gook,Lee Ki Man,Choe Kang Hyeon,Lee Hyun,Yang Bumhee 대한의학회 2023 Journal of Korean medical science Vol.38 No.31
Background: Although poor oral health is a common comorbidity in individuals with airflow limitation (AFL), few studies have comprehensively evaluated this association. Furthermore, the association between oral health and the severity of AFL has not been well elucidated. Methods: Using a population-based nationwide survey, we classified individuals according to the presence or absence of AFL defined as pre-bronchodilator forced expiratory volume in 1 second/forced vital capacity < 0.7. Using multivariable logistic regression analyses, we evaluated the association between AFL severity and the number of remaining teeth; the presence of periodontitis; the Decayed, Missing, and Filled Teeth (DMFT) index; and denture wearing. Results: Among the 31,839 participants, 14% had AFL. Compared with the control group, the AFL group had a higher proportion of periodontitis (88.8% vs. 79.4%), complete denture (6.2% vs. 1.6%), and high DMFT index (37.3% vs. 27.8%) (P < 0.001 for all). In multivariable analyses, denture status: removable partial denture (adjusted odds ratio [aOR], 1.12; 95% confidence interval [95% CI], 1.04–1.20) and complete denture (aOR, 1.52; 95% CI, 1.01– 2.05), high DMFT index (aOR, 1.13; 95% CI, 1.02–1.24), and fewer permanent teeth (0–19; aOR, 1.32; 95% CI, 1.12–1.52) were significantly associated with AFL. Furthermore, those with severe to very severe AFL had a significantly higher proportion of complete denture (aOR, 2.41; 95% CI, 1.11–3.71) and fewer remaining teeth (0–19; aOR, 2.29; 95% CI, 1.57–3.01). Conclusion: Denture wearing, high DMFT index, and fewer permanent teeth are significantly associated with AFL. Furthermore, a reduced number of permanent teeth (0–19) was significantly related to the severity of AFL. Therefore, physicians should pay attention to oral health in managing patients with AFL, such as chronic obstructive pulmonary disease.
급성 뇌경색증에서 항응고제나 혈전 용해제 사용후 발생한 급성 뇌경막하혈종
김근창,임영진,김형두,김태성,김국기,이봉암,임언 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.1
Patients with cardiogenic embolic stroke may experlence an early, recurrent cerebral embolism. Fortunately, limited evidence suggests that anticoagulatory agents or thrombolytic agents may prevent recurrent cardiogenic emboli and halt progression of so-called “progressing stroke”. However, because of the possibility of the intracerebral hemorrhage, use of such agents has generally been considered cautiously with timing, dosage and patient selection. Serious complications of anticoagulation for presumed embolic stroke are hemorrhage in the area of infarction. We experienced two patients with nonseptic cerebral embolism of cardiac origin. They were managed with anticoagulant or thrombolytic therapy, but resulted in clinical deterioration or death from spontaneous subdural hemorrhage. In each patient, an initial CT scan excluded the presence of hemorrhage but a second CT scan after clinical deterioration, documented subdural hemorrhage.
뇌지주막하 출혈환자에서 입원양상 및 치료경과에 대한 최근 5년 간격의 차이에 대한 비교 분석 : 1987년~1992년
김근창,김국기,김형두,임영진,김태성,이봉암,임언 대한신경외과학회 1995 Journal of Korean neurosurgical society Vol.24 No.12
Aneurysmal subarachnoid hemorrhage is a neurosurgical emergency. Early and intensive medical intervention is important for minimizing the occurrence of rebleeding and vasospasm. The purpose of this study was to document and compare the admission or referral pattern, management outcome and attitude of the general public of subarachnoid hemorrhage(SAH) patients over a five year interval of 1987 and 1992. The authors analzyed 229 SAH cases diagnosed by computerized tomography (CT) or lumbar puncture ; 106 cases diagnosed in 1987 were compared to 123 cases diagnosed in 1992. The results of the study showed that 1) the performance rate of angiography and operation have increased in 1992 as compared to 1987. 2) Early admission rate(within 0∼1 day after the onset of SAH) have increased in 1992(84%) as compared to 1987(38%), and delayed admission rate(more than 2 days after the onset of SAH) have decreased in 1992 as compared to 1987. 3) Overall management mortality have decreased from 34% to 20% and operative mortality, from 12% to 4% in 1987 and in 1992, respectirely. It is concluded that the rate of early admission and operation of SAH patients have increased and operative results and overall management outcome of such patients have improved in 1992 as compared to 1987.
맞대기 V형 그루브의 GMA 초층용접에서 합성곱 신경망을 이용한 이면비드 발생 예측 모델 개발
이형원(Hyung Won Lee),유지영(Jiyoung Yu),김광국(Gwang-Gook Kim),김영민(Young-Min Kim),황인성(Insung Hwang),이승환(Seung Hwan Lee),김동윤(Dong-Yoon Kim) 대한용접·접합학회 2021 대한용접·접합학회지 Vol.39 No.5
Gas metal arc (GMA) welding is widely used in the machinery industry. The quality of a welded joint is affected by the penetration of root pass welding in the V-groove joint. Automation using GMA welding is continuously required, and root pass welding automation is required to automate the entire welding process. In particular, the development of a prediction model that can ensure full penetration back-bead is required for the automation of root pass welding. In this study, a convolutional neural network (CNN) model was applied to predict the occurrence of back-bead in V-groove butt joint GMA root pass welding. The bead profile was measured using a laser vision sensor system and it was used as the input data for the prediction model, and the bead occurrence was used as the output data for the model. A total of 12,873 bead profiles were extracted and pre-processed through cutting, resizing, and thresholding. The CNN model consists of nine layers, and performs three convolution and two pooling operations. The accuracy of the prediction model was 99.5%, and through this study, it was demonstrated that the quality of root-pass welding can be controlled by using convolutional neural network and it can contribute to automation.