http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Qi Wang,Hongjian Liu,Zheng Ren,Wenjing Xiong,Minfu He,Nan Li,Xinwen Fan,Xia Guo,Xiangrong Li,Hong Shi,Shuang Zha,Xiumin Zhang 대한신경정신의학회 2020 PSYCHIATRY INVESTIGATION Vol.17 No.4
Objective This study aims to explore the relationships of family functioning, general well-being, and exercise with psychological distress. Furthermore, we investigated the special roles of general well-being and exercise on the association between family functioning and psychological distress. Methods Of 769 end-stage renal disease (ESRD) patients participated in the cross-sectional study which consisted of the 12-item General Health Questionnaire (GHQ-12), the Family APGAR Scales, and the General Well-Being Schedule. The collected data were analyzed using multiple linear regression analysis and path analysis. Results The prevalence of psychological distress was 72.3%. Family functioning, general well-being and exercise were associated factors of psychological distress (p<0.05). The indirect effect of family functioning on psychological distress was partially mediated by general well-being (Effect=-0.08, 95% CI=-0.11, -0.04). In addition, the effect of family functioning on general well-being was moderated by exercise (Index=-0.092, SE=0.033, 95% CI=-0.159, -0.029). Conclusion The prevalence of psychological distress among ESRD patients was high. Family functioning, general well-being and exercise were associated with psychological distress. Family functioning could affect psychological distress partially by affecting general wellbeing. Furthermore, exercise had a significant moderating effect on the relationship between family functioning and general well-being.
InGaN-based photoanode with ZnO nanowires for water splitting
Kangjunjie,Dang Vinhquang,Li Hongjian,문성진,Li Panpan,Kim Yangdoo,Kim Chaehyun,Choi Hakjong,Liu Zhiqiang,Lee Heon 나노기술연구협의회 2016 Nano Convergence Vol.3 No.34
The water splitting properties of InGaN photoanodes equipped with ZnO nanowires were examined in this study. Over the solar spectrum range, the absorbance exhibited a remarkable increase due to the enhanced light absorption caused by the ZnO nanowires. By varying the ZnO nanowires length, the photo-to-current density of photoanodes was increased from 0.017 to 0.205 mA/cm2 at 1.23 V versus reversible hydrogen electrode. Consequently, the incident-photon-to-current efficiency was increased by a factor of 5.5 as the ZnO nanowires growth time increased from 2 to 4 h. The results of this research demonstrate the importance of light absorbance and the surface reaction sites of photoanodes on energy harvesting.
Li Xiaojuan,Dong Guangping,Fang Jianmin,Liu Hongjian,Guo Wanlin,Yin Huayang 한국곤충학회 2020 Entomological Research Vol.50 No.7
Dastarcus helophoroides (Fairmaire) (Coleoptera: Bothrideridae) is an effective ectoparasitoid of pine sawyer beetle Monochamus alternatus Hope (Coleoptera: Cerambycidae) which is the major median insect for transmission of pine wood nematode, Bursaphelenchus xylophilus (Steiner et Buhrer) Nickle (Aphelenchida: Parasitaphelenchidae). A sensitive and acute olfactory system is extremely essential for newly hatched larva of D. helophoroides to forage for a host. Therefore, we established the transcriptome of newly hatched D. helophoroides larvae and characterized the expression profiles of olfactory genes. We identified 20 transcripts encoding putative odorant binding proteins (OBPs), 11 putative chemosensory proteins (CSPs), 9 putative odorant receptors (ORs), 11 putative ionotropic receptors (IRs), 7 putative gustatory receptors (GRs) and 4 putative sensory neuron membrane proteins (SNMPs) olfactory genes from the transcriptome of newly hatched D. helophoroides larvae. According to the phylogenetic analysis, 3 OBPs (DhelOBP6, DhelOBP14 and DhelOBP19), 1 CSP (DhelCSP11), 1 OR (DhelOrco1), 3 IRs (DhelIR3, DhelIR6 and DhelIR8), 3 GRs (DhelGR2, DhelGR4 and DhelGR5) and 2 SNMPs (DhelSNMP1 and DhelSNMP3) had high similarities with reported Coleopteran species. The highest expressed olfactory gene was DhelCSP3, followed by DhelOBP8 and DhelCSP2. The expression levels of the majority of OR, IR, GR and SNMP genes were low. These results indicate that CSPs and OBPs may play important roles in the olfactory recognition process in newly hatched D. helophoroides larvae. The findings from the present study are helpful in unraveling the profound mystery between D. helophoroides and M. alternatus, as well as improving the parasitism efficiency of D. helophoroides larvae.
Zhibin Hu,Jun Hu,Junhua Du,Hongjian Liu,Jun Qi 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.10
This paper investigates the optimized distributed fusion filtering (DFF) problem for a class of nonlinear discrete time-varying stochastic systems with randomly occurring uncertainty (ROU) and missing measurements (MMs). The stochastic nonlinearity is depicted in terms of statistical means. The phenomena of the ROU and MMs are considered during the modelling of state equation and measurement output respectively, which are characterized by Bernoulli distributed random variables. In order to deal with the effect of the parameter uncertainty, the method that the local estimation error covariances and cross-covariances from all estimators at every sample time are replaced by their upper bounds is adopted. Moreover, the minimum upper bounds for each filtering error covariance (FEC) are obtained by designing the corresponding filter gains. Based on the local filters, a new robust DFF algorithm is developed via the matrix-weighted fusion method. In addition, a sufficient condition concerning on the performance analysis of the developed algorithm is given, which can show that the boundedness of the upper bound for each FEC is guaranteed. Finally, a numerical example is provided to manifest the usefulness of the developed distributed fusion algorithm.
Hu Binwu,Wang Peng,Zhang Shuo,Liu Weijian,Lv Xiao,Shi Deyao,Zhao Lei,Liu Hongjian,Wang Baichuan,Chen Songfeng,Shao Zengwu 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-
Compression-induced apoptosis of nucleus pulposus (NP) cells plays a pivotal role in the pathogenesis of intervertebral disc degeneration (IVDD). Recent studies have shown that the dysregulation of mitochondrial fission and fusion is implicated in the pathogenesis of a variety of diseases. However, its role in and regulatory effects on compression-induced apoptosis of NP cells have not yet been fully elucidated. Heat shock protein 70 (HSP70) is a major cytoprotective heat shock protein, but its physiological role in IVDD, especially its effect on mitochondrial fission and fusion, is still unknown. Herein, we found that compression could induce mitochondrial fission, which ultimately trigger apoptosis of NP cells via the mitochondrial apoptotic pathway. In addition, we identified the cytoprotective effects of HSP70 on NP cells, and we found that promoting the expression of HSP70 could protect NP cells from abnormal mechanical loading in vitro and in vivo. Finally, we showed that HSP70 inhibited compression-induced mitochondrial fission by promoting SIRT3 expression, thereby attenuating mitochondrial dysfunction and the production of reactive oxygen species and ultimately inhibiting the mitochondrial apoptotic pathway in NP cells. In conclusion, our results demonstrated that HSP70 could attenuate compression-induced apoptosis of NP cells by suppressing mitochondrial fission via upregulating SIRT3 expression. Promoting the expression of HSP70 might be a novel strategy for the treatment of IVDD.
Xia, Xiaojing,Che, Yanyi,Gao, Yuanyuan,Zhao, Shuang,Ao, Changjin,Yang, Hongjian,Liu, Juxiong,Liu, Guowen,Han, Wenyu,Wang, Yuping,Lei, Liancheng Korean Society for Molecular and Cellular Biology 2016 Molecules and cells Vol.39 No.5
During the lactation cycle of the bovine mammary gland, autophagy is induced in bovine mammary epithelial cells (BMECs) as a cellular homeostasis and survival mechanism. Interferon gamma ($IFN-{\gamma}$) is an important antiproliferative and apoptogenic factor that has been shown to induce autophagy in multiple cell lines in vitro. However, it remains unclear whether $IFN-{\gamma}$ can induce autophagy and whether autophagy affects milk synthesis in BMECs. To understand whether $IFN-{\gamma}$ affects milk synthesis, we isolated and purified primary BMECs and investigated the effect of $IFN-{\gamma}$ on milk synthesis in primary BMECs in vitro. The results showed that $IFN-{\gamma}$ significantly inhibits milk synthesis and that autophagy was clearly induced in primary BMECs in vitro within 24 h. Interestingly, autophagy was observed following $IFN-{\gamma}$ treatment, and the inhibition of autophagy can improve milk protein and milk fat synthesis. Conversely, upregulation of autophagy decreased milk synthesis. Furthermore, mechanistic analysis confirmed that $IFN-{\gamma}$ mediated autophagy by depleting arginine and inhibiting the general control nonderepressible-2 kinase (GCN2)/eukaryotic initiation factor $2{\alpha}$ ($eIF2{\alpha}$) signaling pathway in BMECs. Then, it was found that arginine supplementation could attenuate $IFN-{\gamma}$-induced autophagy and recover milk synthesis to some extent. These findings may not only provide a novel measure for preventing the $IFN-{\gamma}$-induced decrease in milk quality but also a useful therapeutic approach for $IFN-{\gamma}$-associated breast diseases in other animals and humans.
Liancheng Lei,Xiaojing Xia,Yanyi Che,Yuanyuan Gao,Shuang Zhao,Changjin Ao,Hongjian Yang,Juxiong Liu,Guo-wen Liu,Wenyu Han,Yuping Wang 한국분자세포생물학회 2016 Molecules and cells Vol.39 No.5
During the lactation cycle of the bovine mammary gland, autophagy is induced in bovine mammary epithelial cells (BMECs) as a cellular homeostasis and survival mecha-nism. Interferon gamma (IFN-) is an important antiproliferative and apoptogenic factor that has been shown to induce autophagy in multiple cell lines in vitro. However, it remains unclear whether IFN- can induce autophagy and whether autophagy affects milk synthesis in BMECs. To understand whether IFN- affects milk synthesis, we isolated and purified primary BMECs and investigated the effect of IFN- on milk synthesis in primary BMECs in vitro. The results showed that IFN- significantly inhibits milk synthesis and that autophagy was clearly induced in primary BMECs in vitro within 24 h. Interestingly, autophagy was observed following IFN- treatment, and the inhibition of autophagy can improve milk protein and milk fat syn-thesis. Conversely, upregulation of autophagy decreased milk synthesis. Furthermore, mechanistic analysis con-firmed that IFN- mediated autophagy by depleting argi-nine and inhibiting the general control nonderepressible-2 kinase (GCN2)/eukaryotic initiation factor 2 (eIF2) signaling pathway in BMECs. Then, it was found that arginine supplementation could attenuate IFN--induced autophagy and recover milk synthesis to some extent. These findings may not only provide a novel measure for preventing the IFN--induced decrease in milk quality but also a useful therapeutic approach for IFN--associated breast diseases in other animals and humans.
Comparative transcriptome analysis of root hairs proliferation induced by water deficiency in maize
Tingchun Li,Huaying Yang,Wei Zhang,Dafeng Xu,Qing Dong,Fang Wang,Yanli Lei,Guihu Liu,Yingbing Zhou,Hongjian Chen,Cheng Li 한국식물학회 2017 Journal of Plant Biology Vol.60 No.1
Root hairs functions as water channels and nutritional components transporters in plants. It has been shown to enhance nutrient uptake including phosphate, nitrogen, potassium and calcium. In the experiment, the droughtinduced root hairs were collected. By transcriptome sequence and analysis, the molecular mechanisms and differentially expressed genes related to root hairs growth and development were studied. As a result, by using the HiSeq 2500 platform, 61,872,790 clean reads with 96.23% Q20 bases and 9.28 Gb clean bases with 58.88% GC ratio were obtained for normal root. In contrast with Control group, 67,650,572 clean reads with 96.43% Q20 bases and 10.15 Gb clean bases with 58.3% GC content were obtained for drought-induced root hairs. Totally, 323 differentially expressed genes (DEGs) were identified. Among these DEGs, 109 genes were upregulated and 214 genes were downregulated in drought-induced root hairs. Moreover, metabolic pathway enrichment analysises on the 323 DEGs revealed that totally 10 metabolic pathways were distinctly regulated. In details, alanine, aspartate and alutamate metabolism, galactose metabolism and nitrogen metabolism were significantly upregulated. 7 metabolic pathways such as phenylpropanoid biosynthesis, phenylalanine metabolism, biosynthesis of secondary metabolites and flavonoid biosynthesis were significantly downregulated. Furthermore, functional genes and transcription factors were both found to be involved in drought-induced root hair proliferation. These results will help us understand better the molecular mechanism of maize root hair growth and development.