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      • A REVIEW OF STUDIES ON OCEAN TIDES AND MEAN SEA LEVEL IN CHINA

        Guo Hong Fang,Wen Zhen Zheng 한국해안해양공학회 1999 학술강연회 발표논문초록집 Vol.1 No.1

        The observation, analysis, prediction and dynamical studies on ocean tides and tidal currents in China in the recent 50 years are reviewed in the present paper. The major achievements and problems are reported. During recent 50 years, many tidal stations have been established and many short-period current observations have been carried out. The confusion in gauge zero existing in historical tidal data is considered as a most serious problem, and long-period current observations are still limited. Methods for analyzing and predicting tides and tidal currents have been developed. Tide and tidal current tables and charts published are sufficient for practical applications. Progresses in theoretical studies have also been achieved, in particular, on the effects of the friction on tides and tidal currents. Numerical modeling has become a popular measure in tidal prediction. Many studies on relative sea level rise have been carried out. Most of investigations indicate that the rising rates are around zero for the northern China coast and in the range of 1-2 ㎜/a for the southern China coast. However, acquisition of more reliable long-term sea level data is still required.

      • KCI등재

        Real-time hydrogen mud logging during the Wenchuan earthquake fault scientific drilling project (WFSD), holes 2 and 3 in SW China

        Zhen Fang,Yaowei Liu,Duoxing Yang,Lishuang Guo,Lei Zhang 한국지질과학협의회 2018 Geosciences Journal Vol.22 No.3

        We present hydrogen gas concentration data for drilling mud extracted during the Wenchuan Earthquake Fault Scientific Drilling (WFSD; holes 2 and 3), measured on-line during drilling in SW China. Hydrogen influx into the well at depth is largely dependent on lithology and fracture density. In hole WFSD-2, the average background concentration of hydrogen is lower in granitic rocks than in sedimentary formations. More than five major hydrogen influxes were detected while drilling through the sedimentary formations, and two hydrogen-rich zones were detected in the granite (1240–1243 m and 1383.5–1405 m depth). In hole WFSD-3, mud extracted from a tectonic breccia contains high hydrogen concentrations at depths of 600–1000 m depth, and relatively low concentrations below 1000 m depth. In both holes, we observe a lack of hydrogen in the center of the fault zone and high concentrations of hydrogen in fractured zones. Hydrogen concentration in both holes displays significant vertical heterogeneity, and is positively correlated with fracture density. Hydrogen was likely sourced from interaction between water and fresh silicate minerals surfaces that were exposed during faulting, from the mantle, and from faulting events. Fracture zones provide the main channels for the migration of hydrogen gas. The variations in background hydrogen concentrations relate to changes in porosity and permeability. The two hydrogen-rich zones (642.36–676.22 m, and 1383.5–1405 m) were likely caused by earthquake activity or far-field triggering during WFSD-2 drilling. The results of this study provide gas data that can be used to model fault activity. It is important to consider the relationship between hydrogen gas and the seismic cycle, and to use such data to identify seismic precursors.

      • KCI등재

        Dynamic network biomarker identifies cdkn1a-mediated bone mineralization in the triggering phase of osteoporosis

        Guo Weiming,Jin Peng,Li Ruomei,Huang Lu,Liu Zhen,Li Hairui,Zhou Ting,Fang Bing,Xia Lunguo 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-

        The identification of predictive markers to determine the triggering phase prior to the onset of osteoporosis is essential to mitigate further irrevocable deterioration. To determine the early warning signs before osteoporosis, we used the dynamic network biomarker (DNB) approach to analyze time-series gene expression data in a zebrafish osteoporosis model, which revealed that cyclin-dependent kinase inhibitor 1 A (cdkn1a) is a core DNB. We found that cdkn1a negatively regulates osteogenesis, as evidenced by loss-of-function and gain-of-function studies. Specifically, CRISPR/Cas9-mediated cdkn1a knockout in zebrafish significantly altered skeletal development and increased bone mineralization, whereas inducible cdkn1a expression significantly contributed to osteoclast differentiation. We also found several mechanistic clues that cdkn1a participates in osteoclast differentiation by regulating its upstream signaling cascades. To summarize, in this study, we provided new insights into the dynamic nature of osteoporosis and identified cdkn1a as an early-warning signal of osteoporosis onset.

      • KCI등재

        World Health Organization survey on the level of integration of traditional Chinese medicine in Chinese health system rehabilitation services

        Lei Fang,Ran-ran Zhu,Zhen Sang,Xiao-ting Xu,Lin-yun Zheng,Yanwei Xiang,Chaoyang Guo,Zhenrui Li,Stephane Alexandre Espinosa,Qi Zhang,Chunlei Shan 한국한의학연구원 2023 Integrative Medicine Research Vol.12 No.2

        Background: To meet the growing global demand for rehabilitation services, the World Health Organization (WHO) launched Rehabilitation 2030. This study was commissioned by the WHO to investigate the integration degree of traditional Chinese medicine (TCM) in Chinese health system rehabilitation services and the demand for TCM rehabilitation in China. Methods: Twenty TCM rehabilitation experts and relevant government administrators were invited to complete the questionnaire between September 2019 and January 2022. The development of traditional, complementary, and integrative medicine (TCI) rehabilitation in China was assessed primarily based on six different health system components. Results: 26 policies, regulations, and national strategic plans related to TCI rehabilitation were issued by relevant government departments since 2002; notably, 14 policies related to TCI rehabilitation development were intensively introduced from 2016 to 2021. These policies cover the three main areas of financing, infrastructure development, and service delivery. The National Administration of Traditional Chinese Medicine's investment in TCM clinical capacity infrastructure and scientific research in 2019–2021 increased by 66% compared to 2010–2012, and the average number of TCM hospitals with rehabilitation departments in 2020 increased by 6.5% compared to 2018. The proportion of community health service centers providing TCM services in primary medical and health institutions has increased by 30.8% over the past 10 years. Conclusion: Long-term continuous policies, substantial financial investment, and expansion of the scope of TCI rehabilitation services in primary care institutions have effectively contributed to the rapid development of TCI rehabilitation. However, human resources and financing mechanisms for TCI rehabilitation need further improvement.

      • Downregulated MicroRNA-133a in Gastric Juice as a Clinicopathological Biomarker for Gastric Cancer Screening

        Shao, Juan,Fang, Peng-Hua,He, Biao,Guo, Li-Li,Shi, Ming-Yi,Zhu, Yan,Bo, Ping,Zhang, Zhen-Wen Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.5

        Circulatory miR-133a is a marker shared by several types of cancer. In this study we evaluated the feasibility of using miR-133a levels in gastric juice to screen for gastric cancer. A total of 204 samples of gastric juice and mucosa from gastric cancer, atrophic gastritis, gastric ulcer, superficial gastritis and healthy cases were collected by gastroscopy. The results showed that miR-133a levels in gastric juice and carcinoma tissues of patients with gastric cancer were significantly downregulated and positively correlated. Moreover, miR-133a in gastric juice has high operability, high reliability, high sensitivity, high specificity and relative stability, fit for clinical diagnosis of gastric cancer.

      • Mechanical behavior and chloride resistance of cementitious composites with PE and steel fiber

        Liao, Qiao,Guo, Zhen-wen,Duan, Xin-zhi,Yu, Jiang-tao,Liu, Ke-ke,Dong, Fang-yuan Techno-Press 2021 Advances in concrete construction Vol.12 No.6

        The mechanical behaviors and chloride resistance performance of fiber reinforced cementitious composites (FRCC) with hybrid polyethylene (PE) and steel fiber (in total 2% by volume) were investigated. Based on micro-mechanics and fracture mechanics, the reason why the tensile strain capacity of FRCC changed obviously was obtained. Besides, the effects of the total surface area of fiber in FRCC on compressive strength and chloride content were clarified. It is found that the improvement of the tensile strain capacity of FRCC with hybrid fiber is attributed to the growth of strain-hardening performance index (the ratio of complementary energy to crack tip toughness). As the total surface area of fiber related with the interfacial transition zone (ITZ) between fiber and matrix increases, compressive strength decreases obviously. Since the total surface area of fiber is small, the chloride resistance performance of FRCC with hybrid PE and steel fiber is better than that of FRCC containing only PE fiber.

      • KCI등재

        Synchronization for a Class of Fractional-order Linear Complex Networks via Impulsive Control

        Na Liu,Jie Fang,Wei Deng,Zhen-Jun Wu,Guo-Qiang Ding 제어·로봇·시스템학회 2018 International Journal of Control, Automation, and Vol.16 No.6

        Up to now, the research topic about fractional-order complex networks is mainly focused on the synchronization. In this paper, synchronization for a class of fractional-order linear complex networks is realized via impulsive control. The general expression of solution for a fractional-order impulsive error system is deduced by utilizing iteration algorithm. Some inequality conditions are established to guarantee that the largest Lyapunov exponents of each node are negative, which means that the corresponding error system is asymptotic stable and synchronization is realized. It is the first time to achieve the synchronization of fractional-order systems based on the largest Lyapunov exponent. Finally, examples are present to illustrate the validity and effectiveness of proposed conclusions. Numerical simulations also indicate that the fractional-order parameter has a great influence on the largest Lyapunov exponent, although it is not reflected in the theoretical analysis.

      • KCI등재

        Research on the Comprehensive Benefit Evaluation of Electric Vehicle Technology Promotion and Application Under the Strategic Background of “Carbon Peaking and Carbon Neutrality”

        Jia Dexiang,Li Xinda,Guo Shaodong,Liu Fang,Fu Chengcheng,Huang Xingde,Dong Zhen,Liu Jing 대한전기학회 2024 Journal of Electrical Engineering & Technology Vol.19 No.3

        On the one hand, as a substitute for traditional fuel vehicles, electric vehicles (EV) is an important measure to achieve “carbon peak and carbon neutralization” in transportation. On the other hand, as an energy storage unit in the new power system, it can make up for the disadvantages brought by renewable energy power generation. Therefore, scientifc and efective evaluation of EV benefts is the premise to promote the development of EV. In view of the characteristics of EV involving many interest groups and huge market potential, this paper introduces the comprehensive evaluation theory in operations research: analytic hierarchy process (AHP) and entropy weight method, and combines the respective advantages of the two methods to avoid the distortion of evaluation results caused by a single evaluation method. First of all, under the background of building a new power system and realizing a powerful automobile country, the EV promotion beneft evaluation index system is constructed from fve frst-class indexes and 18 s-class indexes of consumers, distribution network, charging network, social beneft and environmental beneft. Then, aiming at the shortcomings of single evaluation method, the subjective and objective combination method of AHP entropy weight method is established to solve each weight index, so as to realize the scientifc quantifcation of the index. Finally, a certain area of a coastal city is selected for example analysis. The results show that the evaluation method established in this paper has a positive efect on EV promotion, and can provide suggestions for EV promotion.

      • KCI등재

        Prevalence, Risk Factors, and Psychological Effects of Primary Nocturnal Enuresis in Chinese Young Adults

        Hui Jie Hu,Zhen Wei Zhang,Yu Liang,Yan Yan Luo,Qi Feng Dou,Cui Ping Song,Hui Min Zhang,Ying Zhao,Guang Run Tian,Ke Zhang,Qiu Fang Mao,Jing Gui Song,Soren Rittig,Jian Guo Wen 대한배뇨장애요실금학회 2021 International Neurourology Journal Vol.25 No.1

        Purpose: This study aimed to investigate the prevalence, risk factors, and effects of primary nocturnal enuresis (PNE) on physical and mental health in young adults in mainland China. Methods: An anonymous questionnaire was used to collect information including the sociodemographic characteristics, history of PNE, family history, daytime voiding symptoms, Pittsburgh Sleep Quality Index (PSQI) scores, Self-Esteem Scale (SES), and Self-Rating Depression Scale (SDS). A total of 22,500 university students from 23 provinces and 368 cities in mainland China were included. Results: In total, 21,082 questionnaires were collected, and 20,345 of them qualified for statistical analysis. The PNE prevalence was 1.17%, and the distribution of monosymptomatic nocturnal enuresis (MNE) and nonmonosymptomatic nocturnal enuresis (NMNE) was 66.1% and 33.9%, respectively. In total, 28% of respondents with PNE reported bedwetting daily, 31.6% between 1 and 7 times weekly, and 40.4% between 1 and 4 times monthly; 80% of PNE cases had no history of treatment. The prevalence of PNE in patients with a family history, frequency, urgency, urinary incontinence, and recurrent urinary tract infections was significantly higher than in those without these conditions (P<0.001). PNE was significantly correlated with the PSQI total score (sleep quality) (P=0.011). The SES score was lower and the SDS was higher (P<0.001) in the PNE group than in those without PNE. Conclusions: In mainland China, the PNE prevalence among young adults was found to be high, and PNE had significant effects on physical and mental health. Risk factors included a family history, daytime voiding symptoms, and lack of treatment.

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