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Combined chemotherapy and intra-arterial chemotherapy of retinoblastoma
Choi, Saerom,Han, Jung Woo,Kim, Hyosun,Kim, Beom Sik,Kim, Dong Joon,Lee, Sung Chul,Lyu, Chuhl Joo The Korean Pediatric Society 2013 Clinical and Experimental Pediatrics (CEP) Vol.56 No.6
Purpose: Retinoblastoma (RB) is the most common primary malignant intraocular tumor in children. Although systemic chemotherapy has been the primary treatment, intra-arterial chemotherapy (IAC) represents a new treatment option. Here, we performed alternate systemic chemotherapy and IAC and retrospectively reviewed the efficacy and safety of this approach. Methods: Patients diagnosed with intraocular RB between January 2000 and December 2011 at Severance Children's Hospital, Yonsei University, were reviewed. Before February 2010, the primary treatment for RB was chemotherapy (non-IAC/CTX). Since February 2010, the primary treatment for RB has been IAC (IAC/CTX). External beam radiotherapy or high-dose chemotherapy were used as "last resort" treatments just prior to enucleation at the time of progression or recurrence during primary treatment. Enucleation-free survival (EFS) and progression-free survival were assessed. Results: We examined 19 patients (median age, 11.9 months; range, 1.4 to 75.6 months) with a sum of 25 eyes, of which, 60.0% were at advanced Reese Ellsworth (RE) stages. The enucleation rate was 33.3% at early RE stages and 81.8% at advanced RE stages (P=0.028). At 36 months, EFS was significantly higher in the IAC/CTX group than in the non-IAC/CTX group (100% vs. 40.0%, P=0.016). All 5 patients treated with IAC achieved eye preservation, although most patients were at advanced RE stages (IV-V). Conclusion: Despite the limitation of a small sample size, our work shows that an alternative combined approach using IAC and CTX may be safe and effective for eye preservation in advanced RB.
장애 특성과 정도에 따른 보완·대체 의사소통 도구 사용자 인터페이스의 구성요소 및 관리
최새롬(Saerom Choi),홍기형(Ki-Hyung Hong),박기태(Kitae Bak) 한국HCI학회 2012 한국HCI학회 학술대회 Vol.2012 No.1
의사소통 요구를 충족시키는데 도움을 주는 보완·대체 의사소통(Augmentative and Alternative Communication, 이하 AAC) 도구를 필요로 하는 장애인구가 점점 증가하고 다양해지는 현대 사회에서 장애의 특성과 정도에 맞추어 개별적으로 사용하기 위해서는 맞춤형 사용자 인터페이스(User Interface, 이하 UI)와 컨텐츠가 필요하다. 본 논문에서는 맞춤형 AAC 도구의 인터페이스에 필요한 구성요소와 관리방안에 대해 제안하였다. With the increased population using Augmentative and Alternative Communication(AAC) devices to meet communication needs and diverse characteristics of modern society, it is necessary to provide the efficient way to customize user interface(UI) and contents according to individual's disability characteristics and levels of severity. This study suggests basic components for customized AAC UI and their management strategies.
Saerom Lee,Jun-Pyo Myong,Eun-A Kim,Huisu Eom,Bowha Choi,Young Joong Kang 대한직업환경의학회 2017 대한직업환경의학회지 Vol.29 No.-
Background: We examined the current status of specialized agencies for occupational health management (SAs) and their workforce. Furthermore, we aimed to clarify the current practice status of SA healthcare professionals and factors that influence their performance. Methods: To examine the current SA workforce, we analyzed data from the 2014 Survey of Current Status of SA and their Workforce from the Ministry of Employment and Labor (MOEL). Furthermore, we mailed out an original questionnaire to SA professionals to determine their current health management status and factors that affect their performance. Data from the respondents (N = 384) were analyzed. Results: In 2014, the workforce performing health management in SAs comprised 232 physicians, 507 nurses, and 312 occupational hygienists, with no significant regional differences in the distribution of physicians and nurses. According to the findings of the questionnaire, the average daily number of worker consultations by physicians and nurses was 22.8, while the average time taken for health management ranged from 74.3 to 104.3 min, depending on the size of the firm. Most of the respondents (41.5%) answered that they were following-up on more than 80% of individuals with illnesses. Among health management tasks, performance scores of “consultations for general diseases” and “consultations for lifestyle habits” were relatively high, whereas health promotion activities at workplaces were relatively low. There was a significant correlation between the utilization of general and special health examination results and task performance. Conclusion: Among health management tasks, follow-up management of individuals with illnesses and consultations for disease/lifestyle habits were relatively well performed, whereas health promotion activities at workplaces were not performed well. Among factors that positively influenced SA performance at workplaces, only the utilization of health examination results had significant effects. Therefore, to accomplish health management goals and perform effective health management at workplaces, there is a need to establish a comprehensive system of occupational health service outsourcing integrating health examinations and health management services. Furthermore, the current task system, which focuses on follow-up management, should be expanded to incorporate preventive and health promotion functions—the fundamental functions of occupational health services (OHS).
임새롬(Im, Saerom),최경식(Choi, Kyeongsik) 한국교원대학교 융합교육연구소 2022 융합교육연구 Vol.8 No.1
이 연구는 음악교육의 성공적인 목적 달성을 위한 예비음악교사 대상 융합기반음악교육 수업을 설계한 것이다. 이를 위해 Maxine Greene의 예술교육철학과 LCE예술교육, 융합교육을 고찰한 후 세 분야의 공통점과 특성을 고려하여 도출한 핵심적인 수업원리를 활용하였다. 설계 내용은 융합기반 음악교육의 수업목적과 수업설계의 방향, 수업단계, 성취기준 및 성취수준을 설정하고 수업모형을 선정 후 세부내용으로 조직하였다. 이 수업은 융합기반 음악교육을 통해 예비음악교사의 미적 경험과 음악 중심의 융합 역량을 강화함으로써 수업 전문성 및 긍정적 정체성을 향상시키는 데 목적이 있다. 학습자의 개념 발달과 이해를 바탕으로 학습자가 의미를 재조직화할 수 있도록 구성주의에 입각한 ‘의식적 주목-체화 인지-의미 창조의 수업단계를 가지며, 각 단계는 강의, 교사 모델링, 마이크로티칭으로 구성된다. 6영역의 성취기준 및 ‘아쉬운-가능성 있는-우수한’의 서술형 3단계 성취수준으로 구분하였고, 수업모형은 Bybee의 5Es를 선정하였다. 한 학기 과정으로 총 12회기에 걸쳐 이루어지는 이 수업은 예비음악교사들이 수업 전문성을 발휘하여 자신의 음악적 삶뿐 아니라 학습자들의 삶에 음악이 깊이 자리하도록 안내할 수 있는 음악교사로 성장하게 할 것을 기대한다. This study designed convergence-based music education classes for prospective music teachers to achieve the successful purpose of music education. To this end, after contemplating Maxine Greene s philosophy of art education, LCE art education, and convergence education, the core teaching principles derived in consideration of the commonalities and characteristics of the three fields were used. To this end, after contemplating Maxine Greene s philosophy of art education, LCE art education, and convergence education, the core teaching principles derived in consideration of the commonalities and characteristics of the three fields were used. To this end, after contemplating Maxine Greene s philosophy of art education, LCE art education, and convergence education, the core teaching principles derived in consideration of the commonalities and characteristics of the three fields were used. This class aims to improve teaching expertise and positive identity by strengthening aesthetic experiences and music-oriented convergence capabilities for prospective music teachers through convergence-based music education. Based on learners concept development and understanding, there is a class stage of conscious attention-embodied recognition-meaning creation based on constructivism so that learners can reorganize their meanings, and each stage consists of lectures, teacher modeling, and micro-teaching. There are 6 areas of achievement standards and the descriptive three-step achievement level of not enough-possible-outstanding were divided, and the class model was selected as Bybee’s 5Es. This class, which runs for a total of 12 sessions for a semester, is expected to help prospective music teachers grow into music teachers who can guide music deeply into learner’s lives as well as their own musical lives by demonstrating their teaching expertise
Gastric and rectal cancers in workers exposed to asbestos: a case series
Byeong Ju Choi,Saerom Lee,Iu Jin Lee,Soon Woo Park,Sanggil Lee 대한직업환경의학회 2020 대한직업환경의학회지 Vol.32 No.-
Background: The Occupational Safety and Health Research Institute (OSHRI) of the Korea had not recognized gastrointestinal cancer as work-related disease during their evaluation. However, in 2018 OSHRI recognized gastric and rectal cancers as work-related disease in asbestos-exposed workers. We present 2 such cases along supportive evidence of causation. Case presentation: Patient A: A 57-year-old man had worked for about 40 years since 1978 as an oxygen cutter at workplaces that dismantle ships, buildings, boilers, and thermal power plants. In November 2016, endoscopy and biopsy confirmed the diagnosis of advanced gastric cancer, for which he underwent subtotal gastrectomy and chemotherapy; however, he later died of the cancer. Patient B: A 71-year-old man had worked in shipbuilding and repair workplaces for approximately 49 years, being employed in pipe laying, asbestos insulation installation, grinding, and other ship repair work. In 2003, he was diagnosed of rectal cancer by abdominal computed tomography. He accordingly underwent surgical removal of the cancer. Based on the occupational history of the 2 patients and our review of the relevant literature addressing the occupational environment, we concluded that both patients had continuous exposure to high levels of asbestos while performing their jobs for 40 and 49 years, respectively. Conclusion: Both patients had a history of smoking and drinking (non-occupational personal risk factors). However, the possibility of an increased risk of gastric and rectal cancers from asbestos exposure cannot be excluded. Therefore, we considered that occupational exposure to asbestos had contributed to the cancer diagnosis in these cases. Workers exposed to asbestos should be made aware of the possibility of gastric or rectal cancer, and should undergo monitoring and medical examinations. Appropriate compensation for gastric and rectal cancers that occur in workers exposed to asbestos are anticipated in future.