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      • KCI등재

        An Accurate Model of Multi-Type Overcurrent Protective Devices Using Eigensystem Realization Algorithm and Practice Applications

        Chao-Yuan Cheng,Feng-Jih Wu 대한전기학회 2016 Journal of Electrical Engineering & Technology Vol.11 No.1

        Accurate models of the characteristics of typical inverse-time overcurrent (OC) protective devices play an important role in the protective coordination schemes. This paper presents a novel approach to determine the OC protective device parameters. The approach is based on the Eigensystem Realization Algorithm which generates a state space model to fit the characteristics of OC protective devices. Instead of the conventional characteristic curves, the dynamic state space model gives a more exact fit of the OC protective device characteristics. This paper demonstrates the feasibility of decomposing the characteristic curve into smooth components and oscillation components. 19 characteristic curves from 13 typical and 6 non-typical OC protective devices are chosen for curvefitting. The numbers of fitting components required are determined by the maximum absolute values of errors for the fitted equation. All fitted equations are replaced by a versatile equation for the characteristics of OC protective devices which represents the characteristic model of a novel flexible OC relay, which in turn may be applied to improve the OC coordination problems in the subtransmission and distribution systems.

      • SCIESCOPUSKCI등재

        An Accurate Model of Multi-Type Overcurrent Protective Devices Using Eigensystem Realization Algorithm and Practice Applications

        Cheng, Chao-Yuan,Wu, Feng-Jih The Korean Institute of Electrical Engineers 2016 Journal of Electrical Engineering & Technology Vol.11 No.1

        Accurate models of the characteristics of typical inverse-time overcurrent (OC) protective devices play an important role in the protective coordination schemes. This paper presents a novel approach to determine the OC protective device parameters. The approach is based on the Eigensystem Realization Algorithm which generates a state space model to fit the characteristics of OC protective devices. Instead of the conventional characteristic curves, the dynamic state space model gives a more exact fit of the OC protective device characteristics. This paper demonstrates the feasibility of decomposing the characteristic curve into smooth components and oscillation components. 19 characteristic curves from 13 typical and 6 non-typical OC protective devices are chosen for curve-fitting. The numbers of fitting components required are determined by the maximum absolute values of errors for the fitted equation. All fitted equations are replaced by a versatile equation for the characteristics of OC protective devices which represents the characteristic model of a novel flexible OC relay, which in turn may be applied to improve the OC coordination problems in the sub-transmission and distribution systems.

      • SCIESCOPUSKCI등재

        The Effects of Chicken Leg Bone Extract on Antioxidative Properties under Different Heating Condition

        Cheng, Fu-Yuan,Wan, Tien-Chun,Huang, Chao-Wei,Tominaga, Kana,Lin, Liang-Chuan,Sakata, Ryoichi Asian Australasian Association of Animal Productio 2008 Animal Bioscience Vol.21 No.12

        The aim of this study was to extract chicken leg bone, which is a by-product of industrial poultry processing, using different heating temperatures (80, 90 and $100^{\circ}C$) and durations (5, 10 and 15 min). The pH value, soluble protein content, peptide content and antioxidative properties, including superoxide anion scavenging ability, 1, 1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging ability, reducing capacity and inhibitory activity of linoleic acid peroxidation, were measured. The results showed no significant differences (p>0.05) in pH value among all treatments. Decreased soluble protein content and peptide content were observed in chicken leg bone extract obtained under higher heating temperatures (90 or $100^{\circ}C$) and longer heating durations (10 or 15 min). In antioxidative properties, the extracts which were heated at 90 or $100^{\circ}C$ for 15 min exhibited significantly higher superoxide anion scavenging ability, DPPH free radical scavenging ability, reducing capacity and inhibitory activity of linoleic acid peroxidation (p<0.05).

      • Implications for new physics from <sup>B¯0</sup>→<sup>π0</sup><sup>π0</sup> and <sup>B¯0</sup>→<sup>K¯0</sup><sup>K0</sup>

        Cheng, Jian-Feng,Gao, Yuan-Ning,Huang, Chao-Shang,Wu, Xiao-Hong Elsevier 2006 Physics letters: B Vol.637 No.4

        <P><B>Abstract</B></P><P>We have analyzed the <SUP>B¯0</SUP>→<SUP>π0</SUP><SUP>π0</SUP> puzzle in three kinds of models beyond the standard model (SM). It is shown that the minimal flavor violation (MFV) models, the minimal supersymmetric standard model (MSSM), and the two Higgs doublet models (2HDM) I and II cannot give an explanation of the <SUP>B¯0</SUP>→<SUP>π0</SUP><SUP>π0</SUP> puzzle within 1<I>σ</I> experimental bounds and the model III 2HDM can explain the puzzle without a conflict with other experimental measurements. If the constraint on <SUB>C8g</SUB> from b→sg is not imposed, for all kinds of insertions considered there are regions of parameter space, where the scalar quark mass is larger (much larger) than the gluino mass in the case of <I>LR</I> or <I>RL</I> (<I>LL</I> or <I>RR</I>), in which the puzzle can be resolved within 1<I>σ</I> experimental bounds.</P>

      • KCI등재

        Applying technological organization environmental model to examine the adopting intention of e-freight for the air freight forwarder

        Ching-Cheng Chao,Fang-Yuan Chen,Ching-Chiao Yang,Chien-Yu Chen 인하대학교 정석물류통상연구원 2016 JOURNAL OF INTERNATIONAL LOGISTICS AND TRADE Vol.14 No.1

        The e-freight program launched by the International Air Transport Association (IATA) has gradually become a standard specification for international air freight operations. This study examined critical factors affecting air freight forwarders’ decision to adopt the IATA e-freight using a technology-organization-environment model with air freight forwarders in Taiwan as the base. Our findings show that ‘information technology (IT) competence’, ‘trading partner pressure’, ‘government policy’ and ‘competitive pressure’ all have significant positive effects on air freight forwarders’ decision to adopt the e-freight and the top three factors among these are ‘government funding’, ‘government’s active promotion’ and ‘government’s requirement of electronic air waybill (e-AWB)’. Finally, this study proposes strategies that can encourage air freight forwarders to decide on e-freight adoption for the information of relevant oK regyawniozradtison International Air Transport Association (IATA); IATA e-freight; Technology organization environment model; Air freight forwarder

      • SCIESCOPUSKCI등재

        Antioxidative Activities of Hydrolysates from Duck Egg White Using Enzymatic Hydrolysis

        Chen, Yi-Chao,Chang, Hsi-Shan,Wang, Cheng-Taung,Cheng, Fu-Yuan Asian Australasian Association of Animal Productio 2009 Animal Bioscience Vol.22 No.11

        Duck egg white (DEW) hydrolysates were prepared by five enzymes (papain, trypsin, chymotrypsin, alcalase, and flavourzyme) and their antioxidant activities investigated in this study. DEW hydrolyzed with papain (DEWHP) had the highest peptide content among the five enzymatic treatments. Besides, the peptide content of DEWHP increased when the enzyme to substrate ratio (E/S ratio) increased. It was suggested that higher E/S ratio contributed to elevate the degree of hydrolysis of DEW effectively. Similar results were also obtained by Tricine-SDS-PAGE. In addition, SDS-PAGE patterns indicated papain was the only one amongst all enzymes with the ability to hydrolyze DEW. In antioxidant properties, DEWHP showed more than 70% of inhibitory activity on linoleic acid peroxidation and superoxide anion scavenging. Moreover, the $Fe^{2+}$ chelating effect of DEWHP was greater than 90%, while no significant difference was observed in DPPH radical scavenging and reducing ability. The results of peptide contents, antioxidant activities and electrophoresis suggested that the higher the peptide content, the stronger the antioxidant activities in DEWHP.

      • KCI등재

        Suture Repair in Endoscopic Surgery for Craniovertebral Junction

        Mei-Yin Yeh,Wen-Cheng Huang,Jau-Ching Wu,Chao-Hung Kuo,Hsuan-Kan Chang,Tsung-Hsi Tu,Peng-Yuan Chang,Yu-Shu Yen,Henrich Cheng 대한척추신경외과학회 2019 Neurospine Vol.16 No.2

        Objective: Endoscopic approaches to the craniovertebral junction (CVJ) have been established as viable and effective surgical treatments in the past decade. One of the major complications is leakage of the cerebrospinal fluid (CSF). This study aimed to investigate the efficacy and feasibility of suture closure at the nasopharyngeal mucosa upon durotomy. Methods: A series of consecutive patients who underwent different endoscopic approaches to the CVJ were retrospectively reviewed. The pathologies, surgical corridors, neurological and functional outcomes, radiological evaluations, and complications were analyzed. Different strategies of repair for the intraoperative CSF leakage were described and compared. Results: A total of 22 patients covering 13 years were analyzed. There were 12, 2, and 8 patients who underwent transnasal, transoral, and combined approaches, respectively. There were 8 patients (36.4%) who experienced intraoperative CSF leakage, and were grouped into 2: 4 in the nonsuture (NS) group and 4 in the suture-repaired (SR) group. The NS group had 3 (75%) persistent CSF leakages postoperation that caused 1 mortality, whereas patients of the SR group had only 1 minor CSF rhinorrhea that healed spontaneously within days. Conclusion: In this series of 22 patients who required anterior endoscopic resection of pathologies at the CVJ, there was 1 (4.5%) serious complication related to CSF leakage. For patients who had no durotomy, the mucosal incision at the nasopharynx usually healed rapidly and there were few procedure-related complications. For patients with intraoperative CSF leakage, suture closure was technically challenging but could significantly lower the risks of postoperative complications.

      • Expression and Clinical Significance of REPS2 in Human Esophageal Squamous Cell Carcinoma

        Zhang, Hang,Duan, Chao-Jun,Zhang, Heng,Cheng, Yuan-Da,Zhang, Chun-Fang Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.5

        Objective: REPS2 plays important roles in inhibiting cell proliferation, migration and in inducing apoptosis of cancer cells, now being identified as a useful biomarker for favorable prognosis in prostate and breast cancers. The purpose of this study was to assess REPS2 expression and to explore its role in esophageal squamous cell carcinoma (ESCC). Methods: Protein expression of REPS2 in ESCCs and adjacent non-cancerous tissues from 120 patients was analyzed by immunohistochemistry and correlated with clinicopathological parameters and patient outcome. Additionally, thirty paired ESCC tissues and four ESCC cell lines and one normal human esophageal epithelial cell line were evaluated for REPS2 mRNA and protein expression levels by quantitative RT-PCR and Western blotting. Results: REPS2 mRNA and protein expression levels were down-regulated in ESCC tissues and cell lines. Low protein levels were significantly associated with primary tumour, TNM stage, lymph node metastasis and recurrence (all, P < 0.05). Survival analysis demonstrated that decreased REPS2 expression was significantly associated with shorter overall survival and disease-free survival (both, P < 0.001), especially in early stage ESCC patients. When REPS2 expression and lymph node metastasis status were combined, patients with low REPS2 expression/lymph node (+) had both poorer overall and disease-free survival than others (both, P < 0.001). Cox multivariate regression analysis further revealed REPS2 to be an independent prognostic factor for ESCC patients. Conclusions: Our findings demonstrate that downregulation of REPS2 may contribute to malignant progression of ESCC and represent a novel prognostic marker and a potential therapeutic target for ESCC patients.

      • Efficacy and Safety of 12 Weeks of Daclatasvir, Asunaprevir Plus Ribavirin for the Treatment of HCV Genotype 1b Infection without Baseline NS5A Resistance-Associated Variants (DARING)-Interim Report

        ( Ming-lung Yu ),( Chao-hung Hung ),( Yi-hsiang Huang ),( Cheng-yuan Peng ),( Chun-yen Lin ),( Pin-nan Cheng ),( Rong-nan Chien ),( Shih-jer Hsu ),( Chen-hua Liu ),( Jee-fu Huang ),( Chung-feng Huang 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

        Aims: The current study aims to elucidate the treatment efficacy (defined as undetectable HCV RNA throughout 12 weeks of post-treatment follow-up, SVR12) and safety DCV/ASV plus ribavirin for 12 weeks in HCV-1b patients without NS5A RAS. Methods: This is a single-arm, open-label phase 2 study. Seventy directly acting antivirals (DAA)-naïve HCV-1b patients without L31/Y93 RAS are planned to receive daclatasvir (60 mg/ day) and asunaprevir (100 mg twice daily) plus weight-based ribavirin (1000-1200 mg/day) for 12 weeks. After treatment they were followed up for 12 weeks. Results: As of 31 Oct 2017, 58 eligible patients are allocated to treatment, with a mean age of 59.3 years and female predominance (67.2%, 39/58). The mean HCV RNA was 5.87+0.77 log10 IU/mL; 23 patients (39.7 %) had significant hepatic fibrosis (>F2). In the modified intention-to-treat analysis, the rate of undetectable HCV at week 1, week 2, week 4, week 8 and endof- treatment was 25 % (14/56), 84.8 % (39/46), 100 % (46/46), 100 % (38/38) and 100 % (27/27), respectively. Undetectable HCV RNA were observed in all of the patients with HCV RNA assessable 4 weeks (SVR4, 18/18) and 12 weeks (SVR12, 12/12) post treatment. None of the 18 patients who completed the 12-week treatment experienced relapse during post-treatment follow-up. The most common adverse event was fatigue (78.3 %), followed by pruritus (65.2 %) and dizziness (52.2 %), of which were considered as ribavirin related. None of the participating subjects withdrew treatment or follow-up throughout the trial peroid. Three serious adverse events were reported which included urosepsis, appendicitis and left ureteral stone. All were unrelated to the investigating drugs. Conclusions: 12 weeks of DCV/ASV plus ribavirin was highly effective and safe in HCV-1b patients without NS5A RAS in the interim analysis. The satisfactory results would be anticipated in the full patient set.

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