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( Chao Chun Yang ),( Chun Te Lee ),( Chao Kai Hsu ),( Yi Pei Lee ),( Tak Wah Wong ),( Sheau Chiou Chao ),( Julia Yu Yun Lee ),( Hamm Ming Sheu ),( Wenchieh Chen ) 대한피부과학회 2013 Annals of Dermatology Vol.25 No.4
Background: Spontaneous recovery of severe alopecia areata is rare and the condition is difficult to treat. Objective: The aim of this study is to investigate and compare the effects and safety of steroid pulse therapy between oral and intravenous administrations between 1999 and 2010 at the Department of Dermatology, National Cheng Kung University Hospital. Methods: Data were retrospectively retrieved. A satisfactory response was defined as more than 75% hair regrowth in the balding area. Results: A total of 85 patients with more than 50% hair loss were identified and treated, with an overall satisfactory response rate of 51.8%. The mean follow-up time was 37.6 months, with a relapse rate of 22.7%. Patients with alopecia areata (hereafter, AA) of recent onset within one year showed higher response rates (p< 0.001) and lower relapse rates compared to patients with AA persisting for more than 1 year. Further, even in patients with alopecia totalis, alopecia universalis or ophiasis type, early treatment resulted in a satisfactory response rate of 47% among the treated patients. In general, oral therapy was as effective and well-tolerated as intravenous therapy. Conclusion: The response rate is determined by disease severity and time of intervention, not by the administration form of steroid pulse therapy. Oral steroid pulse therapy can be considered as the first-line treatment for patients with severe AA of recent onset within one year. (Ann Dermatol 25(4) 471∼474, 2013)
Chao Yang,Yicheng Liu,Fangmin Li,Yangfan Li 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.1
This paper investigates the problem of the finite-time synchronization of a class of coupled memristorbased recurrent neural networks (MRNNs) with time delays. Based on the drive-response concept and differentialinclusions theory, several sufficient assumptions are given to ensure the finite-time synchronization of MRNNs. In order to realize the finite-time synchronization between the drive system and the response system, we designthree classes of novel control rules such as static state controller, static output controller, dynamic state controller. Using the theory of differential inclusion, a generalized finite-time convergence theorem and Lyapunov method, theconditions herein are easy to be verified. Moreover, the upper bounds of the settling time of synchronization areestimated and the designed dynamic state controllers have good anti-interference capacity. Finally, two numericalexamples are presented to illustrate the effectiveness and the validity of theoretical results.
Elastodynamic modeling of spatial parallel manipulators contain subclosed loops
Chao Yang,Yang Wang,Junbin Lou,Wei Ye,Fengli Huang 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.3
In this work, the delta parallel manipulator (PM) was considered as a case study to present a system elastodynamic modeling of spatial PMs contain subclosed loops. The mechanism consisted of major substructures including proximal, short, and distal links. Each link was divided into elements to establish the body-to-body and body-to-ground constraint equations. The global independent generalized displacement coordinates (IGDC) of the mechanism were extracted with the theory of multi-point constraint elements. Besides, the global IGDC and substructure synthesis approach was used to obtain the complete elastodynamic modeling of the mechanism without supplementing constraint equations. The resulting configuration-dependent elastodynamic modeling had fewer degrees of freedom, different from thousands used in finite element model (FEM). The natural frequencies could be predicted at any configuration of the mechanism, and were compared against the values of FEM to assess the correctness of the modeling. The proposed modeling could predict the distribution of natural frequencies of the mechanism in the workspace with computational efficiency. Therefore, it could be used as a numerical twin to simulate the elastodynamic performance of PMs in the pre-design stage.
Monitoring Analysis and Numerical Simulation of the Land Subsidence in Linear Engineering Areas
Chao Jia,Xiao Yang,Jing Wu,Pengpeng Ding,Chao Bian 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.7
Non-uniform land subsidence can cause subgrade deformation and threaten the safety of linear projects such as high-speed railways. The Lunan high-speed railway is taken as the research background. Combined with the hydrogeological and engineering geological conditions, the regional land subsidence is analyzed by the combined method of the differential interferometric synthetic aperture radar (D-InSAR) and small baseline subset interferometric synthetic aperture radar (SBAS-InSAR), which is verified by using precise leveling and GPS monitoring data. The accurate land subsidence analysis of large-scale linear engineering is realized. The distribution situation and change laws of land subsidence in linear engineering areas are revealed. Then, a three-dimensional coupled numerical model of land subsidence along a large-scale linear project is established by using the finite difference method. The spatial distribution characteristics of land subsidence in the linear engineering area are quantitatively analyzed and predicted. The main factors affecting land subsidence and the degree of land subsidence are discussed while keeping the pumping rate constant. The results show that: 1) The combined method of D-InSAR and SBAS-InSAR has high accuracy in the land subsidence monitoring of linear engineering. 2) There are five non-uniform settlement funnels along the Lunan high-speed railway. The groundwater over-extraction and coal mining are the main reasons for the land subsidence. 3) Realizing water source conversion and reduce groundwater exploitation are the main factors in linear engineering areas as soon as possible.
Chao YANG,Toru TAKAHASHI,Takashi YAMADA,Setsuya KURAHASHI,Isao ONO,Takao TERANO 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8
Pattern Oriented Modeling (POM) is an approach to bottom-up complex system analysis which was developed in ecology and for agent-based complex systems. This paper proposes a pattern-oriented agent-based simulation (POABS) approach to analyze agent-based complex system. We apply POABS to a history simulation domain to analyze a particular family line with more successful candidates in the civil service examination in imperial China. In order to decode family strategies along such an elite family line, we develop POABS to test relevant patterns observed in the real family system. Inverse simulation technique is applied to evaluate each simulated pattern through fitting the time-series of simulated profile data to real profile data with real-coded GA. Intensive experiments show a practical applicability of POABS in agent-based complex system.
Transfer matrix for rotor coupler with parallel misalignmen
Chao-Yang Tsai,Shyh-Chin Huang 대한기계학회 2009 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.23 No.5
A transfer matrix for shafts coupler with parallel misalignment (offset) was derived. The responses of a rotor system composed of flexible shafts, unbalanced disks, elastic supports and shafts coupler with misalignment were then investigated. Through the derivation, the boundary shears induced by a rotating shaft were first discovered to be coupled in two perpendicular directions. These coupling shears might reduce the first critical speed up to 50% in the free-free case. The studies showed that the shafts coupler altered the rotor’s critical speeds and the misalignment played as an external load resulting through the whole driven shaft. The combined effects of disk unbalance and shaft misalignment showed that the misalignment predominated the response in most of the rotation speeds, but the unbalance could become significant at high speed. The whirling orbits before and after the misalignment were illustrated as well, and numerical results showed that the two ends of the misalignment whirled asynchronously as the rotation fell into some regions.
Yang Yang,Jinguan Lin,Chao Huang,Xin Ma 한국통계학회 2012 Journal of the Korean Statistical Society Vol.41 No.2
This paper considers an ordinary renewal risk model and a compound renewal risk model with constant interest rate, subexponential claims and a general premium process. We derive some asymptotic results on the finite-time ruin probabilities.