A Comparative Study of heating in Northeast of China

Chao Jia,Kim June Bong 국제온돌학회 2009 International Journal of Ondol Vol.2009 No.-

The research object In this paper is heating in northeast of China, including radiant floor heating systems, radiators and air conditioning. It contains studies the characteristics of these three kinds of heating, and comparing with three systems that their elements of obtaining energy, health, comfort, energy-efficient, heat preservation, health indicators, space utilization and aesthetics. Finally it conclude that radiant floor heating is a scientific, energy, health heating system, and radiant floor heating has great potential for development in China.

Review on the Synthesis and Antioxidation of Cu Nanowires for Transparent Conductive Electrodes

Jia Feng Chao,Yong Qiang Meng,Jingbing Liu,Qian Qian Zhang,Hao Wang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.4

Transparent conducting films based on solution-synthesized copper nanowires (Cu NWs) are considered to be an attractive alternative to indium tin oxide (ITO) due to the relative abundance of Cu and the low cost of solution-phase NW coating processes. Moreover, transparent electrodes tend to be flexible. This makes Cu NWs more attractive because ITO is brittle and can not meet the requirements of flexibility. For Cu NWs, aspect ratio is an important property. Cu NWs can be directly prepared by chemical reduction with various reducing agents and suitable capping agents. In general, the selectivity of the capping agent is very important for the formation of one-dimensional nanostructures because it plays a major role in the thermodynamic regulations and growth kinetics that influence the geometry and morphology of the crystal facets. Therefore, different aspect ratios are formed. Conductivity is the most important property for transparent electrodes. Organic pickling, annealing and glare pulses have a certain improvement in conductivity. Meanwhile, it is also essential to increase the oxidation resistance of the transparent electrode. The reduction of graphene oxide (r-GO), the coating of metal and polymer improve the oxidation resistance of the transparent electrode to varying degrees. This paper reviews the effect of different capping agents on the aspect ratio of NWs, and the effects of different post-treatments on oxidation resistance and conductivity of transparent electrodes.

Right-to-Left Displacement of an Airgun Lead Bullet after Transorbital Entry into the Skull Complicated by Posttraumatic Epilepsy : A Case Report

Chao-bin Wang,Hui Wang,Jun-shuang Zhao,Ze-jun Wu,Hao-dong Liu,Chao-jia Wang,An-rong Li,Dawei Wang,Juntao Hu 대한신경외과학회 2023 Journal of Korean neurosurgical society Vol.66 No.5

Penetrating head injury is a serious open cranial injury. In civilians, it is often caused by non-missile, low velocity flying objects that penetrate the skull through a weak cranial structure, forming intracranial foreign bodies. The intracranial foreign body can be displaced due to its special quality, shape, and location. In this paper, we report a rare case of right-to-left displacement of an airgun lead bullet after transorbital entry into the skull complicated by posttraumatic epilepsy, as a reminder to colleagues that intracranial metal foreign bodies maybe displaced intraoperatively. In addition, we have found that the presence of intracranial metallic foreign bodies may be a factor for the posttraumatic epilepsy, and their timely removal appears to be beneficial for epilepsy control.

Monitoring Analysis and Numerical Simulation of the Land Subsidence in Linear Engineering Areas

Chao Jia,Xiao Yang,Jing Wu,Pengpeng Ding,Chao Bian 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.7

Non-uniform land subsidence can cause subgrade deformation and threaten the safety of linear projects such as high-speed railways. The Lunan high-speed railway is taken as the research background. Combined with the hydrogeological and engineering geological conditions, the regional land subsidence is analyzed by the combined method of the differential interferometric synthetic aperture radar (D-InSAR) and small baseline subset interferometric synthetic aperture radar (SBAS-InSAR), which is verified by using precise leveling and GPS monitoring data. The accurate land subsidence analysis of large-scale linear engineering is realized. The distribution situation and change laws of land subsidence in linear engineering areas are revealed. Then, a three-dimensional coupled numerical model of land subsidence along a large-scale linear project is established by using the finite difference method. The spatial distribution characteristics of land subsidence in the linear engineering area are quantitatively analyzed and predicted. The main factors affecting land subsidence and the degree of land subsidence are discussed while keeping the pumping rate constant. The results show that: 1) The combined method of D-InSAR and SBAS-InSAR has high accuracy in the land subsidence monitoring of linear engineering. 2) There are five non-uniform settlement funnels along the Lunan high-speed railway. The groundwater over-extraction and coal mining are the main reasons for the land subsidence. 3) Realizing water source conversion and reduce groundwater exploitation are the main factors in linear engineering areas as soon as possible.

Regulatory Mechanisms of Annexin-Induced Chemotherapy Resistance in Cisplatin Resistant Lung Adenocarcinoma

Wang, Chao,Xiao, Qian,Li, Yu-Wen,Zhao, Chao,Jia, Na,Li, Rui-Li,Cao, Shan-Shan,Cui, Jia,Wang, Lu,Wu, Yin,Wen, Ai-Dong Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.7

Adenocarcinoma of lung has high incidence and a poor prognosis, woith chemotherapy as the main therapeutic tool, most commonly with cisplatin. However, chemotherapy resistance develops in the majority of patients during clinic treatment. Mechanisms of resistance are complex and still unclear. Although annexin play important roles in various tumor resistance mechanisms, their actions in cisplatin-resistant lung adenocarcinoma remain unclear. Preliminary studies by our group found that in cisplatin-resistant lung cancer A549 cells and lung adenocarcinoma tissues, both mRNA and protein expression of annexins A1, A2 and A3 is increased. Using a library of annexin A1, A2 and A3 targeting combined molecules already established by ourselves we found that specific targeting decreased cisplatin-resistance. Taken together, the underlined effects of annexins A1, A2 and A3 on drug resistance and suggest molecular mechanisms in cisplatin-resistant A549 cells both in vivo and in vitro. Furthermore, the study points to improved research on occurrence and development of lung adenocarcinoma, with provision of effective targets and programmes for lung adenocarcinoma therapy in the clinic.

Estrogen Receptor α Roles in Breast Cancer Chemoresistance

Xu, Chao-Yang,Jiang, Zhi-Nong,Zhou, Ying,Li, Jia-Jia,Huang, Li-Ming Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.7

Resistance to chemotherapy treatment, which may lead to limited efficacy of systemic therapy in breast cancer patients, is multifactorial. Among the mechanisms of resistance to chemotherapy treatment, there are those closely related to estrogen receptor ${\alpha}$, P-glycoprotein, multidrug resistance-related protein, glutathione S-transferase pi and topoisomerase-II. $ER{\alpha}$ is ligand-activated transcription factor that regulates gene expression and plays a critical role in endocrine signaling. In previous preclinical and clinical studies, positive $ER{\alpha}$ expression in breast cancer cells was correlated with decreased sensitivity to chemotherapy. This article reviews current knowledge on the predictive value of $ER{\alpha}$ with regard to response to chemotherapy. Better understanding of its role may facilitate patient selection of therapeutic regimens and lead to optimal clinical outcomes.

Effects of Variants in Proopiomelanocortin and Neuropeptide Y Genes on Growth, Carcass, and Meat Quality Traits in Rabbits

Liu, Wen-Chao,Chen, Shi-Yi,Jia, Xian-Bo,Wang, Jie,Lai, Song-Jia Asian Australasian Association of Animal Productio 2014 Animal Bioscience Vol.27 No.5

Appetite-related neuropeptides proopiomelanocortin (POMC) and Neuropeptide Y (NPY) are essential for regulating feeding behavior and energy homeostasis. The objective of this study was to evaluate the effects of variants in POMC and NPY genes on growth, carcass and meat quality traits in rabbits. A total of six SNPs were identified for POMC (n = 2) and NPY (n = 4) genes by direct sequencing. Three SNPs were subsequently genotyped by using MassArray system (Sequenom iPLEXassay) in 235 individuals, which belong to three meat rabbit breeds, including 93 Ira rabbits; 81 Champagne rabbits and 61 Tianfu black rabbits. The SNP c.112-12G>T was in intron-exon boundaries (intron 1) of POMC gene, and the association analysis showed that individuals with TT genotype had a greater 84 d body weight (BW84), eviscerated weight and semi-eviscerated weight than those with GT genotype (p<0.05); the TT individuals were also higher than those GG in the ripe meat ratio (RMR) (p<0.05). The g.1778G>C SNP, which was in complete linkage with other three SNPs (g.1491G>A, g.1525G>T and g.1530C>T) in intron 1 of NPY gene, was significantly correlated with eviscerated slaughter percentage and semi-eviscerated slaughter percentage in rabbits, and the individuals with CC genotype had a better performance than CG genotype (p<0.05). These findings would provide primary clues for the biological roles of POMC and NPY underlying the rabbit growth-related traits.

Effects of Myogenin on Expression of Late Muscle Genes through MyoD-Dependent Chromatin Remodeling Ability of Myogenin

Chao Du,Ju-Hua Ni,Ya-Qiong Jin,Jun-Juan Qi,Zhen-Xing Ji,Shu-Yan Li,Guo-Shun An,Hong-Ti Jia 한국분자세포생물학회 2012 Molecules and cells Vol.34 No.2

MyoD and myogenin (Myog) recognize sets of distinct but overlapping target genes and play different roles in skeletal muscle differentiation. MyoD is sufficient for near-full expression of early targets, while Myog can only partially enhance expression of MyoD-initiated late muscle genes. However, the way in which Myog enhances the expression of MyoD-initiated late muscle genes remains unclear. Here, we examine the effects of Myog on chromatin remodeling at late muscle gene promoters and their activation within chromatin environment. Chromatin immunoprecipitation (ChIP) assay showed that Myog selectively bound to the regulatory sequences of late muscle genes. Overexpres-sion of Myog was found to overcome sodium butyrate-inhibited chromatin at late muscle genes in differ-entiating C2C12 myoblasts, shifting the transcriptional activation of these genes to an earlier time period. Furthermore, overexpression of Myog led to increased hyperacetylation of core histone H4 in differentiating C2C12 myoblasts but not NIH3T3 fibroblasts, and hyperacetylated H4 was associated directly with the late muscle genes in differentiating C2C12, indicating that Myog can induce chromatin remodeling in the presence of MyoD. In addition, co-immunopre-cipitation (CoIP) revealed that Myog was associated with the nuclear protein Brd4 in differentiating C2C12 myoblasts. Together, these results suggest that Myog enhances the expression of MyoD-initiated late muscle genes through MyoD-dependent ability of Myog to induce chromatin remodeling, in which Myog-Brd4 interaction may be involved.

Flow-induced Orientations of Fibers and Their Influences on Warpage and Mechanical Property in Injection Fiber Reinforced Plastic (FRP) Parts

Chao-Tsai Huang,Jia-Hao Chu,Wei-Wen Fu,Chia Hsu,Sheng-Jye Hwang 한국정밀공학회 2021 International Journal of Precision Engineering and Vol.8 No.3

During the past two centuries, due to too fast growth of the human population, the pollution made by human has seriously impacts on our environment, particularly, for the CO2 emission. To diminish the CO2 emission problem, one of the effective solutions is applying lightweight material, such as the fiber-reinforced plastics (FRP), to replace metal in the manufacturing of transportation vehicles. However, since the reinforced function of the fibers inside plastic matrix is very complex, it is not easy to be visualized and managed. Specifically, the connection from microstructures of the fibers to the physical properties of the final product is far from our understanding. In this study, we have proposed a benchmark with three standard specimens based on ASTM D638 with different gate designs. This system is used to study the fiber microstructures and associated mechanical properties using numerical simulation and experimental studies. Results showed that the tensile properties (including tensile modulus and tensile stress) of all three ASTM standard specimens can be improved significantly in the appearance of the fibers. Moreover, the tensile properties variation of the finished parts associated with the microstructures of the short fibers based on the gate design have been also investigated. Specifically, the tensile modulus and the strength of the Model I are greater than that of Model II, while Model III is much less than others because of its double gate effect. The reason why the tensile modulus and the strength of the Model I is greater than that of Model II is due to some entrance effect. That entrance effect will further provide flow-induced fiber orientation to melt and then enhance the tensile properties of Model I. To confirm the observation, a series simulation and experimental studies have been performed. Specifically, the fiber orientation distribution is predicted using CAE, and verified using micro-CT scan and image analysis by Avizo software. Hence, the correlation from fiber microstructure feature (particularly in fiber orientation) to tensile modulus and tensile stress for fiber reinforced thermoplastic (FRP) in injection molding process can be validated.

On-Line Monitoring of Laser-Drilling Process based on Coaxial Machine Vision

Chao-Ching Ho,Jun-Jia He 한국정밀공학회 2014 International Journal of Precision Engineering and Vol. No.

This paper presents a novel method for monitoring the laser-drilling process for a hole by using machine vision. Through on-lineimage acquisition and analysis during the laser-drilling processes, we could simultaneously obtain correlations between themachining processes and the analyzed images. The depths of laser-machined holes could be estimated on-line by using the machinevision method. Therefore, an inexpensive on-line inspection system was developed to increase productivity. All of the processing workwas performed in air under standard atmospheric conditions with gas assist. A correlation between the area of radiation emitted fromthe vaporized material and the depth of the hole was derived. The results indicate that the estimated depths of the laser-drilled holeswere linearly proportional to the thresholded image area, with a high degree of confidence. This research provides a novel onlinemachine vision–based method for estimating the depths of laser-drilled holes.