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Bayesian Multiple Comparison of Bivariate Exponential Populations based on Fractional Bayes Factor
Cho, Jang-Sik,Cho, Kil-Ho,Choi, Seung-Bae Korean Data and Information Science Society 2006 한국데이터정보과학회지 Vol.17 No.3
In this paper, we consider the Bayesian multiple comparisons problem for K bivariate exponential populations to make inferences on the relationships among the parameters based on observations. And we suggest the Bayesian procedure based on fractional Bayes factor when noninformative priors are applied for the parameters. Also, we give a numerical examples to illustrate our procedure.
Kwang-Soo Cho,Ji-Hong Cho,Bong-Kyoung Yun,Hong-sik Won,Jeong-Ki Jeon,Hwang-Bae Sohn 한국육종학회 2014 한국육종학회 심포지엄 Vol.2014 No.07
The newly developed varieties, Jayoung (violet flesh color) and Hongyoung (red flesh color) that harboring various anthocyanins and flavonoids in flesh colored potato are highly increase their interesting not only for food but also functional characteristics such as anti-inflammatory effects. Up to date, most of the molecular markers developed in potato are linked to disease resistance including late blight and PVY, nematode. A few markers linked to economically important functional materials such as anthocyanin biosynthesis are published. With the low cost and high throughput of NGS (Next Generation Sequencing) technology, numerous molecular markers are highly increased in may crops. Among the molecular markers, SNPs (Single nucleotide Polymorphisms) are most useful markers owing to their large numbers in inter and intra varieties in potato. Here we reported SNPs discovery from transcriptome sequencing data acquired from colored flesh potato cultivars, Jayoung and Hongyoung with white flesh color Atlantic. Total RNA was isolated from shoot in tuber after breaking dormancy about 2cm length. Short read sequence data were obtained form Illumina Hiseq2000 and the raw dat set were trimmed with Q socore over 20. Sequencing data were align to reference genome (Solanum tuberosum v4.03, http://potatogeomics.plantbiolgy.msu.edu). About 70% of sequence read were mapped int to reference genome. 139,050, 140,976 and 146,429 total SNPs were discovered in Hongyoung, Jayoung and Atlantic, respectively. All SNPs are mapped into the psedomolecules in reference genome by chromosome. SNPs are also analyzed with homozygous and heterozygous SNPs and genic and intergenic region. SNPs are compared with Potato Infinium 8K Chip data. SNPs found in candidate genes of anthocyanin biosynthesis were discovered. These SNPs information of flesh colored potato will be further analyzed for the allele mining for anthocyanin syhthesis and control region
성인 요로 감염 환자에서 99mTc - DMSA 삼중검출기 SPECT 영상의 유용성
박정식(Jung Sik Park),문대혁(Dae Hyuk Moon),김순배(Soon Bae Kim),이명혜(Myung Hae Lee),류진숙(Jin Sook Ryu),배원규(Won Gyu Bae),박수길(Su Kil Park),홍창기(Changgi D . Hong),조경식(Kyung Sik Cho) 대한핵의학회 1992 핵의학 분자영상 Vol.26 No.2
N/A Although early diagnosis of urinary tract infection is important, the radiologic evaluation is still controversial because of the low sensitivity and the lack of cost-effectiveness. This study was carried out to evaluate the clinical utility of high resolution triple head Tc-99m-DMSA SPECT imaging in urinary tract infection. We prospectively performed Tc-99m-DMSA planar and SPECT imaging, ultrasound of kidney (US), intravenous pyelography (IVP) and voiding cystourethrography (VCU) in all 60 adult patients with UTI [26 with first episode of acute pyelonephritis (APN), 22 with recurrent APN, and 12 persistent asymptomatic pyuria] and 25 normal persons. To assess reversibility of the renal cortical defect (RCD), Tc-99m-DMSA SPECT was repeated 1 to 8 months later in those patients with abnormal initial findings. Overall detection rate of Tc-99m-DMSA SPECT imaging was 83% (50/60), but planar, US, IVP and VCU showed abnormal findings in 68%, 28%, 32% and 13%, respectively. 25 out of 27 patients with nonnal or single RCD were all normal in other radioligic studies. Only two patients showed vesicoureteral reflux (VUR) on VCU (grade I) and mild hydronephrosis on IVP. But, high proportion of those with multiple RCD showed abnormal findings on US (17/33), IVP (18/33), and VCU (7/33): 67% in any of these 3 studies. Especially, 3 out 7 patients with VUR showed multiple RCD on Tc-99m- DMSA SPECT without any abnormality on IVP or US. 25 normal persons showed normal findings in all studies except one false positive finding on Tc-99m-DMSA SPECT imaging. Follow-up Tc-99m-DMSA SPECT was done in 28 patients (13 with single RCD, 15 with multiple RCD). All 13 patients with single RCD showed improvement. Those with multiple RCD presented improvement in 4, no change in 10, and aggravation in 1 on follow-up studies. With these results, we conclude: 1) Tc-99m-DMSA SPECT imaging is superior to planar imaging, US, IVP or VCU in detection of renal lesion in urinary tract infection. Tc-99m-DMSA SPECT is useful as a initial diagnostic tool in adult patients with urinary tract infection. 2) The multiple RCD on Tc-99m- DMSA SPECT represent the high probability of irreversible tissue change and need of extensive urological work-up.
미세변화 신증후군에 합병된 간문맥, 비장정맥 및 장간막정맥 혈전증
조종태(Jong Tae Cho),김지훈(Ji Hoon Kim),박정식(Jung Sik Park),이상구(Sang Koo Lee),김순배(Soon Bae Kim),양현숙(Hyun Suk Yang),조경식(Kyoung Sik Cho) 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.3
An association between nephrotic syndrome and thromboembolic phenomena has been known for many years. Most common sites of venous throm-bosis in nephrotic syndrome are al vein and deep vein of lower extremity. We report a case of minimal change nephrotic syndrome associated with unusual extensive venous thrombosis. A 29-year-old man was transferred to our hospital with severe abdominal pain and ascites. 2 months before admission, he was diagnosed as minimal change nephropathy at another hospital and treated with steroid therapy but he had persistent proteinuria on admission. The ab- dominal ultrasonography and CT scan revealed diffuse thrombosis of left renal vein, splenic vein, su-perior mesenteric vein and portal vein. Deep vein thrombosis of lower extremity was also found but not pulmonary embolism. There was no evidence of other primary hypercoagulable disease. He was treat- ed with intravenous heparin immediately and three days later, abdominal pain disappeared. Prednisolone and cyclophosphamide were administered as well. After 1 month of therapy, proteinuria was resolved. Abdominal CT scan, taken after 2 months of therapy, revealed that diffuse thrombosis were almost re- solved. From this case, diffuse abdominal thrombosis should be included as a diffrential diagnosis in a ne-phrotic patient with abdominal pain.
측두골 암상부에서 발생한 원발성 연골상 척색종 1례 : Case Report
조무연,최천식,강재영,주문배 대한신경외과학회 1990 Journal of Korean neurosurgical society Vol.19 No.5
The authors report an unusual case of a primary chondroid chordoma arising from the base of the petrous temporal bone. A 43-year-old female presented with left sided facial weakness and left sided jugular foramen syndrome. The CT findings of a tumor arising from the base of left petrous temporal bone and it involved left cerebello-pontine angle, and extended through left jugular foramen to parapharyngeal space. The clinical and histopathologic differences between classical(typical) chordoma and its variant are highlighted. The rarity of primary chordomas at this site is stressed.