Sphingosine-1-Phosphate (S1P)가 이식지방의 생존에 미치는 영향

윤동주,최수종,최치원,남수봉,배용찬,Yoon, Dong-Ju,Choi, Soo-Jong,Choi, Chi-Won,Nam, Su-Bong,Bae, Yong-Chan 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.6

Purpose: Autologous fat grafting is a popular procedure for the correction of the soft tissue depression and deformity. But there are several issues required to be carefully considered in relation to this procedure, mainly about the unpredictability and the low survival rate of the grafted fat due to absorption and partial necrosis. Sphingosine-1-phosphate (S1P) is a lysophospholipid mediator that has been proposed to promote angiogenesis and to regulate the differentiation of adipose derived stromal cells (ASCs). In this study, we analyzed the viability of the grafted fat tissue mixed with S1P into each 12 nude mice (cann.cg-fox1nu/crlori) compared to the group of mice grafted fat tissue only. Methods: Human aspirated fat was grafted subcutaneously into the backs of 8-week-old nude mice with or without S1P. Eight weeks later, the grafted fat was harvested and the weight and volume were checked. The fat was stained with hematoxylin-eosin and 4',6-diamidino-2-phenylindole. Results: S1P group weighed significantly more than the control group (p=0.009), and the volume from the S1P group was considerably larger than that of the control group (p=0.004) either. In histological features, the surviving layer of the S1P group was thicker than the control group and microvasculature appeared to be prominent in the S1P group, especially in the outer layers. Conclusion: These findings suggest that S1P plays a vital role in the soft tissue augmentation, potentially providing a novel point of the control in adipose tissue for microfat graft.

조절 적합 상황에서 인지욕구가 광고효과에 미치는 영향

윤동주(Dong Ju Yoon),박범순(Pumsoon Park) 성신여자대학교 경영연구소 2014 경영관리연구 Vol.7 No.2

본 연구는 소비자의 인지욕구 수준에 따라 조절적합 상황에서 광고효과에 어떠한 차이가 나타나는지 살펴보았다. 제품유형(쾌락재/실용재), 광고메시지의 조절초점(향상메시지/예방메시지)의 조절적합 상황과 소비자의 조절초점성향(향상성향/예방성향), 광고메시지의 조절초점(향상메시지/예방메시지)의 두 가지 조절적합 상황에서 광고 효과는 소비자의 인지욕구가 낮을 때에만 그 차이가 나타날 것으로 예상하였다. 이는 조절적합 상황일 때 항상 긍정적인 결과가 나타나는 것이 아니라 소비자의 인지욕구에 따라서 그 효과가 나타나거나 혹은 나타지 않을 수 있다는 것이다. 분석 결과, 제품유형과 메시지의 조절초점에 대한 광고효과와 소비자의 조절초점 성향과 메시지의 조절초점에 대한 광고효과 모두 저인지욕구의 소비자에게서만 그 차이가 나타났다. 즉 조절적합성효과는 인지욕구가 낮을 때에만 나타난 다는 것이다. 이러한 결과는 다음과 같이 해석할 수 있다. 소비자들이 설득 상황에서 인지욕구 수준에 따라 정보처리 동기의 차이가 나타나기 때문에 대상을 평가할 때 사용하는 정보나 단서의 양이 다를 수 있다. 이 때 인지욕구가 낮을 경우 조절적합상황에서 느끼는 긍정적인 감정을 단서로 활용하여 대상을 평가하기 때문에 조절적합효과가 나타날 가능성이 높지만, 인지욕구가 높을 경우에는 보다 더 다양한 정보나 단서를 활용하여 대상을 평가할 가능성이 높기 때문에 조절적합효과가 나타나지 않을 수 있다는 것이다. 연구를 통해 조절적합성 효과에서 인지욕구가 중요한 변인이 될 수 있음을 확인하였다. In this study, what differences appear in the advertising effects according to the consumer"s need for cognition under the situation that the consumer"s regulatory focus and the advertising message types are fit was examined. First, it was expected that the difference in the advertising effects would appear only when the consumer"s need for cognition is low in the situation of the regulatory fit between the product types(hedonic vs utilitarian) and the regulatory focus (prevention vs promotion) of advertising message types, and in the situation of regulatory fit between the consumer"s regulatory focus (prevention vs promotion) and the regulatory fit of the advertising message types. That is, in the situation of the regulatory fit, the positive results do not always appear but its effect may or may not appear depending on the consumer"s need for cognition. In the analysis results, the advertising effects for both the product types and the regulatory focus of the advertising message types and the consumer"s regulatory focus and the regulatory focus of the advertising message types appeared only in the consumer having low need for cognition. That is, the regulatory fit effect appeared when the need for cognition is low. These results can be interpreted as follows. Since in the persuasive situation, the differences in the information processing motive appear according to the need for cognition, the amount of information or clue used when evaluating the subject may be varied. In this moment, since the subject is evaluated using the positive emotion felt in the situation of the regulatory fit as a clue if the need for cognition is low, the possibility that the regulatory fit effect may appear is high, but since it is likely to evaluate the subject using much diverse information or clues if the need for cognition is high, the regulatory fit effect may not appear. Through this study, it is confirmed that the need for cognition can be the important variable in the regulatory fit effect.

기업의 가치지향성이 업무생산성과 경영성과에 미치는 영향

윤동주(Yoon, Dong-Ju),정대율(Jeong, Dae-Yul) 한국산학기술학회 2014 한국산학기술학회논문지 Vol.15 No.4

본 연구는 국내 IT제조업과 IT서비스업,그리고 비IT제조업을 대상으로 기업의 고객지향성,기술혁신지향성,사회 적 책임지향성이 기업의 경영성과에 어떤 영향을 미치는가를 분석하였다.그 결과 고객가치지향성이 기업의 업무생산성에 영향을 미치며,간접적으로 경영성과지표 향상에 영향을 미치는 것으로 나타났다.또한 기술혁신지향성은 업종이 조절작용을 하며,IT서비스기업의 경우에만 경영성과에 유의적인 영향을 미치는 것으로 나타났다.마지막으로 기업의 사회적 책임지향 성은 업무생산성에는 직접 영향을 미치지 않으나,경영지표 향상에는 영향을 미치는 것으로 나타났다. The purpose of the this study is to analyze what business value orientations are more effective on the enhancement of productivity and performance indexes of IT companies. Especially we are interest in the moderate effect of business types such as IT manufacturing, IT services, and non-IT manufacturing companies. The empirical test results was somehow different from the theoretical researches. Customer orientation affects productivity directly and performance indexes indirectly. Whereas, technology innovation orientation didn't affects productivity and performance indexes directly, except IT services companies. Corporate social responsibility affects performance indexes directly, but not productivity. We could conclude that the type of business is an important moderator between business value orientations and enterprise performance factors.

기술창업기업의 비즈니스모델 특성과 경영성과간의 관계에 대한 탐색적 연구

윤동주(Dong-Ju Yoon),정연수(Yeonsu Jeong),조성의(Sung-Eui Cho) 한국창업학회 2016 한국창업학회 Conferences Vol.2016 No.3

쇼펜하우어의 음악 형이상학

윤동주(Yoon, Dong Ju) 중앙대학교 중앙철학연구소 2018 철학탐구 Vol.49 No.-

본 논문은 쇼펜하우어의 생철학적인 지평에서 ‘존재와 음악’을 화두 삼아 음악과 인간 현존재 간의 내밀한 관계를 발굴하는 것을 기본 목표로 한다. 본고에서 제시한 새로운 이해에 따르면, 존재는 시간 형식을 통해 자신을 음악으로서 개시하고, 이에 인간은 호모 무지쿠스(Homo musikus)로서 음악을 통해 존재이해를 수행하는 ‘음악적 현-존재’(musikalisches Da-sein)이다.—음악은 인간 현존재가 존재이해를 수행하는 ‘탁월한’ 실존양식이다. 요컨대 음악은 단순히 감각적 유희나 관조적 예술로 그치는 게 아니라 존재 개시 및 존재이해가 일어나는 ‘존재론적 진리’ 그 자체이다. 논자는 이러한 새로운 이해에서 쇼펜하우어의 음악 형이상학에 관한 기존의 주장들을 비판적으로 고찰할 것이다. 지금까지 낭만주의, 감정미학, 그리고 한슬릭의 절대음악 이념과 관련하여 쇼펜하우어의 음악 형이상학에 관한 논의들이 있었으며, 이 과정에서 중요한 쟁점들이 노정되었다. 기존의 논의에서 쇼펜하우어를 절대음악론자로 규정하는 경우를 흔히 볼 수 있는데, 이러한 규정은 적절치 않다. 다른 한편으로 쇼펜하우어는 음악을 “철학의 도구”로 삼았다는 달하우스의 주장이 있다. 이는 음악의 자율성과 직결된 문제인데, 논자는 한슬릭의 절대음악 이념을 비판 대상으로 삼아 이 문제를 논구할 것이다. 본고는 쇼펜하우어 철학의 심층으로 파고들어 기존의 주장들을 비판적으로 고찰하고 그의 음악 형이상학이 함축하고 있는, 인간 현존재에 대한 음악의 실존론적 의의를 부각할 것이다. Taking ‘Being and music’(Sein und Musik) as the main talking point, this paper aims to examine Schopenhauer’s doctrine of music in the horizon of his life-philosophy, excavating the intimate relation between music and human-Dasein. A new understanding presented in this treatise is that Being reveals itself as music in the form time, so that humans as Homo musikus are ‘musical Da-sein’(musikalisches Da-sein) performing the understanding of Being(Seinsverständnis) through music. —music is a ‘supreme’ mode of existence in which human-Dasein performs it. To sum up, music is not a mere sensual amusement or contemplative art, but ‘ontological truth’ itself wherein the revealing and understanding of Being takes place. From this new perspective, I will investigate the preceding arguments critically. There have been some debates on Schopenhauer’s metaphysic of music—in terms of Romanticism, the aesthetics of feeling, or Hanslick’s idea of absolute music, in which process main controversial points were exposed. In those preceding debates we can often see Schopenhauer described as a theorist of absolute music, but this is not a very proper determination. Meanwhile, it was asserted by Dahlhaus that Schopenhauer took music as the “organ of philosophy”. This is directly related to the autonomy of music, which I will debate, focusing my criticism on Hanslick’s idea of absolute music. By penetrating into the depth of Schopenhauer’s philosophy, this research will reconsider the precedent assertions critically, and bring to light the existential significance of music for human-Dasein which is implied in his metaphysic of music.

사회적기업의 비즈니스모델 특성과 기업성과간의 관계 연구

윤동주(Dong Ju Yoon),정대율(Dae Youl Jeong),조성의(Sung Eui Cho) 한국창업학회 2013 한국창업학회 Conferences Vol.2013 No.1

본 연구에서는 사회적기업의 비즈니스모렐특성과 기업성과 간에 어떠한 관계가 있는지를 파악해 보았다. 연구결과 비즈니스모웰을 구생하는 가치제안 요소언 목표고객, 가치제공볼과 가치창출 요소언 자원 및 핵섬역량, 내부 가치사슬, 외부 가치네트꿔크 그리고, 가치확보 요소인 수익모형, 비용구조, 성장원리, 혁신지향생 등의 활동이 사회적 기업의 사회쩍 성과와 경제적 성과에 영향을 주논 것으로 확인되었다, 연구의 컬과는 비즈니스포텔 특성이 사회적기업의 성과에 영향을 준다는 점에서 시사점을 갖는다. 즉 사회쩍 기엽은 비즈니스모델을 구체화하고 비즈니스모델을 실행하여 사회척, 경제적 성과를 창출해야한다. In this study, we know that there is relationship between the social enterprise businessmodel characteristics and corporate performance. From the result in this study, Businessmodel characteristics were identified as affecting the social performance and economic performance of social enterprise, the business model elements, target customers, provide valuable things as value proposition, resource and core competencies, internal value chain, external value networks as value creation, revenue model, cost structure, principles of growth, innovation orientation as securing value. From the results, has implications in terms of the business model characteristics will affect the performance of social enterprises. We will need to create social, and economic performance of social enterprise by running the business model and refine the business model.

콘크리트 거동의 수분-열적, 화학-역학적, 환경적 연계반응에 관한 연구

윤동주(Yoon Dong-Ju),송하원(Song Ha-Won),김성훈(Kim Sung-Hoon),변근주(Byun Keun-Joo) 대한토목학회 2000 대한토목학회 학술발표회 논문집 Vol.2000 No.1

STS 304 , 316 강의 열처리에 따른 산화거동

이경구,윤동주,기회봉,강창석,이도재 ( Kyung Ku Lee,Dong Ju Yoon,Whe Bong Ghi,Chang Sug Kang,Doh Jae Lee ) 한국열처리공학회 1998 熱處理工學會誌 Vol.11 No.3

N/A An oxidation behavior of 304 and 316 stainless steels were studied in dry air. After solution treatment, specimens were polished up to 1㎛ A1₂O₃ grade and then subjected to oxidation treatment in dry air at 800℃∼1200℃. The oxidation behavior between matrix and oxide scale was analyzed with SEM, EDS and XRD. When oxidation treatment was conducted at 1200℃, large thickness of Fe oxide scale was formed on top of surface and fine (Cr,Fe)₂O₃oxide film was formed below it. Cr rich zone existed at interface between metal and (Cr,Fe)₂O₃oxide layer, and it was believed that this zone acted as obstacle to oxidation. Most of Ni was detected at the interface between metal and (Cr,Fe)₂O₃and also detected at the interface between Fe₂O₃and (Cr,Fe)₂O₃.

가스텅스텐아크 용접한 클래드(A4045/A3003) 알루미늄 합금의 기계적성질 및 미세조직

김기빈,국진선,윤동주,김병일,이일천,Kim, Ki-Bin,Gook, Jin-Seon,Yoon, Dong-Ju,Kim, Byung-Il,Lee, Il-Cheon 대한용접접합학회 2008 대한용접·접합학회지 Vol.26 No.4

In this paper, research was the variation of microstructure and mechanical properties of clad(A4045/A3003) Al alloy sheet by gas tungsten arc welding. Tensile properties of the gas tungsten arc welding joint decreased because of the softened heat affected zone(HAZ). The hardness of HAZ was lower than that of base metal, because relieved the work hardening effect of the welding heat. Hardness distribution of the weld zone with the base metal appears similarly, but the hardness of HAZ decreased remarkably. The microstructure in the weld zone of A4045 clad layer was formed a coarse columner grains of Si-rich. In the case of large weld heat input, the Si of the A4045 were diffused and until A3003 weld zone they decreased the strength.

MR 및 EMR제조공정에 따른 탄탈륨분말 특성

박형호,윤재식,배인성,김양수,윤동주,원대희,김병일,Park, Hyeoung-Ho,Yoon, Jae-Sik,Bae, In-Sung,Kim, Yang-Soo,Yoon, Dong-Ju,Won, Dae-Hee,Kim, Byung-Il 한국분말야금학회 2007 한국분말재료학회지 (KPMI) Vol.14 No.3

In the metallothermic reduction (MR) process used to obtain tantalum powder in one batch, it is difficult to control the morphology and location of the tantalum deposits. On the other hand, an electronically mediated reaction (EMR) process is capable of overcoming this difficulty. The effect of using $K_2TaF_7$ as the raw material and sodium as the reducting agent on the characteristics of tantalum powder are investigated. As the temperature of the reduction varied from 1023K to 1223K, the powder particles obtained with MR were relatively large $({\sim}34{\mu}m)$, while those prepared via EMR were of uniform $(13{\mu}m)$. In the MR process, the Ta powder recovery rate increased from 37% to 83% at 1123K in constrat with EMR process.