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혈중수은 노출에 따른 일부 초등학생의 건강영향에 관한 연구
김대선,김근배,강택신,이종화,남상훈,Kim, Dae-Seon,Kim, Guen-Bae,Kang, Tack-Shin,Lee, Jong-Hwa,Nam, Sang-Hoon 한국환경보건학회 2007 한국환경보건학회지 Vol.33 No.5
As mercury absorbed into body can cross the blood-brain barrier and react with DNA and RNA. Central nervous system has been known to be affected especially in children. But it was very difficult to know the influences of chronic low-does Hg exposure on the health. Although many studies investigated the affect, most of results were still disparate. In order to investigate the health effects of mercury exposure, several test were conducted for some Korean school children. The general health effects were investigated using blood test, Posturography and computer-based neurobehavioral test was done to examine the affect of Hg into neural responses. About 400 children were chosen for blood test whose blood Hg level were upper and lower 10% of population participated in the nationwide Hg exposure survey. The concentration of calcium and creatine, the number of white and red blood cell showed statistical significance with Hg exposure in blood test. Another 36 children were selected from the same participants for the posturography and neurobehavioral test. The intensity and center frequency of hand tremor which were related to unconsciousness also showed distinct significances. Any general relations with Hg exposure were not found in all test including computer-based neurobehavioral test.
국가산단지역(광양, 여수) 일부 주민들의 소변 중 카드뮴 농도에 관한 연구
박희진 ( Hee Jin Park ),강택신 ( Tack Shin Kang ),이종대 ( Jong Dae Lee ),김근배 ( Geun Bae Kim ),유승도 ( Seung Do Yu ),장봉기 ( Bong Ki Jang ),이종화 ( Jong Wha Lee ),손부순 ( Bu Soon Son ) 한국산업보건학회 2015 한국산업보건학회지 Vol.25 No.3
Objectives: The objective of this study was to evaluate the distribution of urine cadmium levels of residents in the surrounding areas of an industrial complex. Methods: During the period of three month from August to October 2012, informed consent was obtained from a total of 362 residents in Kwangyang and Yeosu. We collected urine sample from all subjects and their demographic characteristics, including alcohol drinks and smoking habits, using a questionnaire. The urine samples were analyzed using atomic absorption spectrometer. Results: The urinary cadmium geometric mean concentration of total participants was 0.87 ㎍/g cr. The results of this study showed that higher urine cadmium levels were observed in females and some subjects with a higher level of education level and a lower BMI. Also, those subjects who preferred to take vegetables and took fish 3 days before urine sampling procedure revealed higher urine cadmium concentrations. The urine cadmium concentrations of subjects in the exposed area(0.91 ㎍/g cr) were significantly higher than those in the control area(0.78 ㎍/g cr). Conclusions: An additional study is needed to assess health risks of residents in the vicinity of environment-unfriendly areas, coupled with endeavors to examine possible heavy metals contamination factors that may affect the human body.
일개 농촌지역의 초등학생과 주민에서 다환성 방향족 탄화수소와 톨루엔 노출이 요중 Thiobarbituric Acid Reactive Substance 농도에 미치는 영향
김대선,이철호,엄상용,강택신,김용대,김헌,Kim, Dae-Seon,Lee, Chul-Ho,Eom, Sang-Yong,Kang, Tack-Shin,Kim, Yong-Dae,Kim, Heon 대한예방의학회 2008 예방의학회지 Vol.41 No.1
Objectives : Polycyclic aromatic hydrocarbons (PAH) and toluene have been reported to induce reactive oxygen species and oxidative stress. This study was performed to investigate the effects of low level exposure to PAHs or toluene on the lipid peroxidation level in elementary school children and the elderly in a rural area. Methods : Forty seven elementary school children and 40 elderly people who were living in a rural area and not occupationally exposed to PAH or toluene were the subjects of this study. Information about active or passive smoking and diet was obtained using a self-administered questionnaire. The urinary 1-hydroxypyrene (1-OHP), 2-naphthol, hippuric acid and thiobarbituric acid reactive substance (TBARS) concentrations were measured, and these values were corrected with the urinary creatinine concentration. Results : In school children, the geometric means of the urinary 1-OHP, 2-naphthol, hippuric acid and TBARS levels were $0.02\;{\mu}mol/mol$ creatinine, $0.47\;{\mu}mol/mol$ creatinine, 0.14 g/g creatinine and $0.95\;{\mu}mol/g$ creatinine, respectively. Those values for the elderly were $0.07{\mu}mol/mol$ creatinine, $1.87{\mu}mol/mol$ creatinine, 0.11 g/g creatinine and $1.18\;{\mu}mol/g$ creatinine, respectively. The mean levels of urinary 1-OHP, 2-naphthol and TBARS were significantly higher in the elderly subjects than in the children. The urinary TBARS level was not correlated with the urinary 1-OHP, 2-naphthol and hippuric acid, but they were correlated with the age of the subjects. Conclusions : These results suggest that low level inhalation exposure to PAH or toluene does not markedly increase lipid peroxidation, and age is a significant determinant of lipid peroxidation.
충남지역 일부 교육시설의 HCHO 및 VOCs 농도 분포에 따른 실내 공기질 평가
박희진(Hee-Jin Park),김효정(Hyo-Jung Kim),우경숙(Kyung-Sook Woo),강택신(Tack-Shin Kang),이종대(Jong-Dae Lee),손부순(Bu-Soon Son) 한국환경교육학회 2013 環境 敎育 Vol.26 No.4
In this study, HCHO and VOCs of 51 schools and 11 child care centers in Chungnam Area were surveyed from March 2011 to January 2012. The concentration of HCHO in the child care centers and the schools were 21.53 ㎍/㎥ and 42.80 ㎍/㎥ respectively. Also, the concentration of VOCs in the child care centers and the schools were 158.90 ㎍/㎥, 192.53 ㎍/㎥ respectively. While the concentration of both substances did not exceed the standards in the child care centers, VOCs (4.98%) was slightly higher than HCHO (8.06%) in the schools. The regional differences in the surveyed area were as follows; the HCHO level of child care center located in urban and rural area were 25.52 ㎍/㎥ and 35.26 ㎍/㎥ respectively. The VOCs concentration in urban and rural area 144.99 ㎍/㎥ and 155.92 ㎍/㎥ respectively. In schools, the concentration of HCHO were 35.73 ㎍/㎥ in rural area level 57.65 ㎍/㎥ in urban area. VOCs level was 243.07 ㎍/㎥ in urban area, which was higly measured than 168.46 of rural area. As the results of the correlation analysis between school environment was highly correlated to the HCHO and the number of students per class (p<0.05).
산단지역 공기 중 휘발성유기화합물농도와 지역주민의 노출 수준
우경숙 ( Kyung Sook Woo ),박희진 ( Hee Jin Park ),강택신 ( Tack Shin Kang ),김근배 ( Geun Bae Kim ),전준민 ( Jun Min Jeon ),장봉기 ( Bong Ki Jang ),이종화 ( Jong Wha Lee ),손부순 ( Bu Soon Son ) 한국산업보건학회 2015 한국산업보건학회지 Vol.25 No.1
Objectives: The purpose of this study is to investigate the atmospheric concentration of VOCs and the urinary concentration of t,t-MA, HA, MA in the industrial complex of Yeosu, South Jeolla Province. Methods: In order to study seasonal patterns of air concentration of VOCs, measurements were taken at five sampling sites around Yeosu from June 2013 to June 2014. Urinary metabolite excretionsfrom 671 subjects, exposure and comparison area were analyzed. Results: The average concentration of VOCs in the air was 1.53ppb for benzene, 0.73ppb for toluene, 0.22ppb for ethylbenzene, 0.52ppb for xylene and 0.12ppb for styrene. The concentration of benzene was somewhat higher than the year-average standard (5 ㎍/㎥, about 1.5ppb) of the domestic air-environment criteria newly established in 2010.The metabolic concentration of VOCs in the urine of the entire sample was analyzed at 47.76μg/g cr., 213.07mg/g cr., and 290.09μg/g cr. for t,t-MA, HA, and MA, respectively. Compared with the average values for Korea as presented in the first basic survey of national environmental conservation (49.8μg/g cr. for t,t-MA, 0.17g/g cr. for HA, and 0.26mg/g cr. for MA), the metabolic concentrations of HA and MA in urine were higher than the average values. Conclusions: The concentration of VOCs in the air and urinary metabolites of the exposed and control areas showed that the concentrations of all substances were higher in the exposed area than in the control area.
여수시의 대기오염과 일별 사망의 상관성에 관한 연구 - 미세먼지와 이산화황을 대상으로 -
박희진 ( Park,Hee Jin ),우경숙 ( Kyung Sook Woo ),정은경 ( Eun Kyung Chung ),강택신 ( Tack Shin Kang ),김근배 ( Geun Bae Kim ),유승도 ( Seung Do Yu ),손부순 ( Bu Soon Son ) 한국환경영향평가학회 2015 환경영향평가 Vol.24 No.1
The association between daily total/cardiovascular mortality and air pollution in Yeosu was investigated over 11-year period (January 2001 to December 2011). The purpose of this study was to evaluate th relative importance of the major air pollutants [particulate matter (PM10), sulfur dioxide (SO2)] as predictors of daily total/cardiovascular mortality. People aged 65 and older showed total mortality increase by 5.0% with SO2 concentration increase by 11.67ppb(IQR) was found to raise mortality caused by circulatory diseases by 8.6%, exhibiting a statistically significant result.
공단지역주민의 요중 비소농도와 혈압과의 관련성에 관한 연구
박희진 ( Hee Jin Park ),우경숙 ( Kyung Sook Woo ),문찬석 ( Chan Seok Moon ),김근배 ( Geun Bae Kim ),강택신 ( Tack Shin Kang ),정은경 ( Eun Kyung Chung ),김용배 ( Yong Bae Kim ),손부순 ( Bu Soon Son ) 한국산업보건학회 2014 한국산업보건학회지 Vol.24 No.2
Objectives: The study examines the relation between urinary arsenic concentration and blood pressure, which is a risk factor of cardiovascular disease. Materials: In this study, the urinary arsenic concentration, history of diagnosed disease, and blood pressure of 782 local residents in Gwangyang, Yeosu, and Hadong regions from May 2007 to July 2007. Results: The urinary arsenic concentration of total participants was 9.06 ㎍/g-ct. The logistic regression analysis of medical diagnosed history and urinary arsenic concentration, showed statistically significance (p<0.05) of high urinary arsenic concentration in participants with diagnosed hypertension. In addition, diagnosed hypertension it was observed that the high blood pressure was related with the pulse pressure. Conclusions: The arsenic concentration level was low in this study, but the exposure to low levels of arsenic has an effect on hypertension. Also, hypertension is related to pulse pressure and mean arterial blood pressure as well as being risk factor of cardiovascular disease. Therefore, close supervision of low -level arsenic exposure is needed.