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기능적 배뇨장애가 방광요관역류 및 신반흔에 미치는 영향
임영재,전형진,한상원 대한비뇨의학회 2005 Investigative and Clinical Urology Vol.46 No.9
Purpose: To report the relationship between voiding dysfunction and reflux, renal scars and the common findings related to voiding dysfunction in patients with vesico-ureteral reflux(VUR). Materials and Methods: Between March 2002 and February 2004, 56 children underwent a video-urodynamic study(video-UDS) for evaluation of VUR. The grade of VUR, various findings of voiding dysfunction and the maximal intravesical pressure(maxPves) were assessed during voiding, and severity of renal scars were assessed via video-UDS and DMSA scans, respectively. Results: Voiding dysfunction was diagnosed in 30 patients(53.6%). The findings of voiding dysfunction were uninhibited contraction(14 patients), detrusor sphincter dyssynergia(15 patients) and bladder neck opening during the filling phase(17 patients). Urethrovaginal reflux and after contraction were noted in 6 and 8 patients, respectively. In the voiding dysfunction group, the mean VUR grade was 3.4, while this was 2.6 in 42 renal units of the normal voiding group(p=0.023). The mean maxPves values during voiding in the voiding dysfunction and normal voiding groups were 107.7 and 77cmH2O, respectively(p=0.002). On evaluation of the relationship between voiding dysfunction and the extent of renal scarring[no scar, single scar, multiple scars, reduced size], the existence of voiding dysfunction resulted in more severe forms of renal scarring (p=0.034). Conclusions: Voiding dysfunction can cause or aggravate VUR or urinary tract infection due to an increased intravesical pressure during voiding, which can ultimately cause permanent renal damage. Therefore, treatments, such as anticholinergic drugs or biofeedback, must be performed in patients with combined VUR and voiding dysfunction for a better treatment outcome
임영재,Im Yeong Jae 대한수의사회 2002 대한수의사회지 Vol.38 No.2
The present study was conducted to investigate the electrophoretic patterns of wild animals by the method of horizontal polyacylamide gel electrophoresis (HPAGE). The results obtained from this study were summarized as follows; 1. At the albumin locus, th
사슴 혈청의 단백량, Bilirubin 농도, Transaminase 활성도 및 Thymol Turbidity
임영재,이상식,정태홍,정순동,Lim Yeong Jae,Lee Sang Sick,Chung Tae Hong,Chung Soon Tong 대한수의사회 1978 대한수의사회지 Vol.14 No.1
In this work the concentration of serum protein and bilirubin, thymol turbidity, and the activities of SGOT and SGPT were examined in deer (one $P\'{e}re$ David's deer, one Red deer and 5 Formosan deer) raising at Yongin Farm Land. The results
임영재,이상식,우영제,정순동,Lim Yeong Jae,Lee Sang Sick,Woo Yeong Jae,Chung Soon Tong 대한수의사회 1979 대한수의사회지 Vol.15 No.5
The blood picture of 3 lions (two males and one female), aging from 2 to 5 months old and raising at Yongin Farm Land, was observed. The results obtained in this work were summerized as follows: 1. Erythrocytic blood picture: Number of erythrocyte $8
Proper Cut-off Value of Free to Total PSA Ratio for Detection of Prostate Cancer in Korean Men
임영재,김재욱,홍성준,정병하 연세대학교의과대학 2004 Yonsei medical journal Vol.45 No.5
To assess whether the free-to-total prostate specific antigen (PSA) ratio (F/T PSA ratio) would enhance prostate cancer detection in Korean men with serum total PSA levels between 4 and 20ng/ml. Methods: A total of 240 consecutive patients whose serum PSA levels were between 4 and 20ng/ml were enrolled in this two-year study. All patients underwent ultrasound-guided transrectal biopsies of the prostate gland. The F/T PSA ratio was measured using the Roche immunoassay. Results: Of the 240 patients, 202 (84%) had benign histologies, while 38 (16%) had prostate cancer. The two patient groups were well matched for age. The mean F/T PSA ratio showed a statistically significant difference between the two groups: in the benign histology group it was 0.14 (0.04-0.37), and 0.10 (0.08-0.20) in the prostate cancer group (p<0.05). Out of the 183 patients with a PSA level between 4-10ng/ml, the mean F/T PSA ratios were 0.14 and 0.11 in the benign histology (n=158) and prostate cancer groups (n=25), respectively (p<0.05). From the 57 patients with a PSA level between 10-20ng/ml, the mean F/T PSA ratios were 0.14 and 0.10 in the benign histology (n=44) and prostate cancer groups (n=13), respectively (p<0.05). Overall, when the cut-off value of the F/T PSA ratio was 0.10, the sensitivity and specificity were 75.0% and 76.5%, while for the cut-off value of 0.15 they were 83.3% and 39.7% respectively. Conclusion: Our data demonstrated the usefulness of the free to total PSA ratio in distinguishing benign prostate disease and cancer disease, hence eliminating unnecessary biopsies. It is recommended that a cut-off value for the F/T PSA ratio of 0.10 be applied to Korean men which this is lower than the value used in Western countries.