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구순열 수술 후 흉터를 가진 영유아 환자에서 흉터 복합 레이저요법의 효과 및 안전성에 대한 단일 기관, 후향적 연구
이주희,최수연,김제민,이영인,이주희 대한피부과학회 2022 대한피부과학회지 Vol.60 No.7
Background: Postoperative scars following cleft lip surgery are frequently accompanied by cosmetic and functional problems; therefore, patients with cleft lip scars usually undergo various long-term scar treatment courses. Currently, only a limited number of fractional laser treatment cases of cleft lip scars have been reported. Objective: This study aimed to evaluate the safety and efficacy of the combination laser treatment for hypertrophic scar management following cleft lip surgery. Methods: This single-center retrospective study included 27 patients who underwent cleft lip surgery before 12 months of age. The control group comprising 13 patients received only a silicone gel or sheet for the scars, while the treatment group comprising 14 patients underwent laser treatment with a 1,550 nm non-ablative fractional erbium-glass laser, followed by a 10,600 nm ablative fractional carbon dioxide laser. Intralesional triamcinolone injection (5∼10 mg/mL) was administered immediately after laser treatment. Scar improvement was assessed at 1, 3, and 6 months after surgery using the Vancouver Scar Scale. Results: The mean total Vancouver scar scale showed a statistically significant improvement in the treatment group compared to that in the control group. In the sub-analysis of pigmentation, the vascularity, pliability, and height significantly improved in the treatment group. No differences in the patients’ baseline characteristics between the two groups were noted. No significant adverse effects were observed during the follow-up. Conclusion: Combination laser therapy using fractional lasers and intralesional triamcinolone injection is safe and effective for managing cleft lip surgery scars in infantile patients.
이주희,김제민,이상규,최수연,이주희,이영인,김지희 연세대학교의과대학 2023 Yonsei medical journal Vol.64 No.12
Purpose: Fractional microneedle radiofrequency (FMR) systems are used to treat inflammatory acne and scarring. Nonetheless, few controlled studies have combined this treatment with the traditional ablative fractional laser (AFL). We aimed to assess the safety and efficacy of the combination of FMR and AFL versus AFL alone in treating acne and acne scars. Materials and Methods: In this 20-week, randomized, split-face study, 23 Korean patients with facial acne and acne scars under went FMR and AFL treatments. One half of each patient’s face was randomly assigned to receive FMR+AFL, whereas the other half received AFL alone. Treatments were administered in three consecutive sessions at 4-week intervals. This study investigated the severity of inflammatory acne, acne scars, individual lesion counts, depressed scar volumes, as well as patient and physician satisfaction. In addition, five patients underwent skin biopsy, and sebum output was measured. Results: The FMR+AFL treatment demonstrated superior efficacy compared to AFL alone in terms of inflammatory acne and acne scar grading, lesion counts, and subjective satisfaction. The side effects were minimal and well-tolerated in both groups. Immuno histochemical findings from skin biopsy samples revealed that the application of FMR+AFL could induce an inhibitory effect on sebum secretion at the molecular level. Conclusion: FMR combined with AFL is a well-tolerated and effective treatment modality for inflammatory acne and acne scarring.
Anti-wrinkle Effects of Cervi Pantotrichum Cornu Pharmacopuncture Solution
이주희,이경민,김재수,임성철,정태영 대한침구의학회 2010 대한침구의학회지 Vol.27 No.4
목적 : 본 연구는 녹용약침액의 주름 개선 효과에 대하여 여러 가지 in vitro 실험을 통해 확인해 보고자 계획되었다. 방법 : 녹용약침액의 항산화효과를 DPPH(1,1-diphenyl-2-picrylhydrazyl) 자유라디칼 소거법을 이용하여 측정하였고, 또, elastase 억제 효과를 측정하였다. 그리고 녹용약침액이 사람 정상 섬유아세포 HS 68에서 UVB 조사 후 type I procollagen의 생산량 회복에 미치는 효과를 ELISA법을 이용하여 측정하였다. 결과 : 녹용약침액에서 우수한 DPPH 자유라디칼 소거 효과가 관찰되었다. 또한 통계적으로 유의한 elastase 활성 억제 효과를 관찰할 수 있었다. 사람 섬유아세포 HS 68을 이용한 실험에서는 녹용약침액 처치군에서 UVB 조사로 감소된 type I procollagen이 유의하게 회복되는 것이 관찰되었다. 결론 : 본 연구 결과에 의하면, 녹용약침액에는 유효한 주름개선 효과가 있어, 미용약침 소재로 개발할 수 있을 것으로 사료된다.
대학의 성폭력 대응 규정 및 절차에 관한 고찰 - 충청 지역 4개 대학의 반성폭력 학칙을 중심으로 -
이주희 한양법학회 2020 漢陽法學 Vol.31 No.1
The #Me Too movement that has hit our society over the past few years has once again confirmed that college is not a free space from sexual violence. On the other hand, it raised questions about whether the existing rules on campus sexual violence at each university were being properly addressed. Therefore, this paper tries to analyze the contents and draw up problems and measures for improvement in order to enhance the effectiveness of the relevant campus rules. The rules on campus sexual violence were introduced in the 1990s under the influence of feminism and the anti-sexual violence movement. Solving incidents at universities by themselves is an important part of the autonomy that universities are guaranteed. However, the rules on campus sexual violence are strongly required to strengthen the effectiveness of cases. Universities should continue their efforts to remove distrust of members in resolving cases in universities and enhance the utilization rate of solutions based on the rules on campus sexual violence. In this regard, the improvement proposed by this paper is as follows. First, it is compulsory to regulate the recruitment of one or more grievance counselors so that professional sexual violence grievance counseling can be done and stipulate the provision of educational opportunities related to the work to enhance the professionalism of counselors. Second, counseling and case investigation are not conducted by the same counselor, so that the counseling and investigation work should be handled by different institutions through the institutional improvement under the rules. Third, for the protection of victims, emergency measures such as quarantine measures of victims and perpetrators and secondary damage prevention measures are prescribed. Fourth, in terms of ensuring the prompt handling of sexual violence cases within the universities, the minimum period for investigation is specified in the rules.