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      • KCI등재

        Transcriptional Regulation of T Helper 17 Cell Differentiation

        황은숙 연세대학교의과대학 2010 Yonsei medical journal Vol.51 No.4

        The third lineage of T helper subsets, Th17, has recently been identified as an IL-17-producing CD4+ Th cell, and its functions and regulatory mechanisms have been extensively characterized in immune responses. Functional studies have provided evidence that Th17 cells are important for the modulation of autoimmune responses, such as chronic asthma, rheumatoid arthritis, inflammatory bowel diseases, and multiple sclerosis. Murine Th17 cell differentiation is enhanced by the coordinated functions of distinct cytokines including TGFβ, IL-6, IL-21, and IL-23, whereas IL-2, IL-4, IFNγ, and IL-27 inhibit its differentiation. In addition,Th17 cells are controlled by several transcription factors such as RORγ t, IRF4,BATF, FoxP3, T-bet, PPARγ, E-FABP, and SOCSs. This review focuses on the functions and regulatory mechanisms of several transcription factors in the control of Th17 cell differentiation.

      • KCI등재

        청소년기 여학생의 월경전증후군 영향요인

        황은숙,강정희 사단법인 인문사회과학기술융합학회 2019 예술인문사회융합멀티미디어논문지 Vol.9 No.8

        The purpose of this study was to identify factors associated with premenstrual syndrome among adolescent female students. The participants were 111 third grade girls from a middle school in J city. A questionnaire survey was conducted from June to July 2017 to collect data on participants’ characteristics, premenstrual syndrome, menstrual pain, menstrual attitude, academic stress, and social support. Data were analyzed with the SPSS/WIN 20.0 program using descriptive statistics, t-test, ANOVA, Scheffe’s test, Person’s correlation, and multiple regression. The participants’ premenstrual syndrome was significantly positively correlated with menstrual attitude and academic stress. A total of 48.0% of variances in premenstrual syndrome were explained by dysmenorrhea and academic stress. In order to prevent or control premenstrual syndrome in adolescent girls, a strategy or an intervention program needs to be developed toward reducing menstrual attitude and academic stress. 본 연구는 청소년기 여학생의 월경전증후군 영향 요인을 파악하기 위해 실시된 서술적 조사연구이다. 전북지역 일 중학교에서 편의표집한 3학년 재학생 111명을 대상으로 2017년 6월부터 7월까지 2개월 동안 설문지를 사용하여 자료를 수집하였다. 설문지는 대상자 특성, 월경전증후군, 월경통, 월경태도, 학업스트레스, 사회적지지 등을 묻는 문항으로 구성하였다. 자료는 SPSS/WIN 20.0 프로그램을 이용하여 t-test, ANOVA, Scheffe검정, Pearson‘s correlation, stepwise multiple regression으로 분석하였다. 연구 결과, 대상자들의 월경전증후군은 월경태도, 학업스트레스와 순상관 관계를 보였고, 대상자들의 월경전증후군에 영향을 미치는 주요 요인은 월경통과 학업스트레스로 나타났으며, 이들 두 변수의 설명력은 48.0%이었다. 청소년기 여학생의 월경전증후군을 예방하거나 조절하기 위한 중재프로그램은 대상자들의 월경태도를 긍정적으로 변화시키고 학업스트레스를 감소시킬 수 있는 방향으로 개발하는 것이 바람직할 것이다.

      • KCI등재
      • 한부모가정의 복지로서의 반편견교육 고찰

        황은숙 한국한부모가정학회 2014 한국한부모가정학 Vol.7 No.2

        이 연구는 정부의 한부모가정의 복지정책이 생계급여 등 경제적인 지원에 머물고 있는 것을 지적하고, 한부모가정의 복지를 인권보호 및 인권 증진 사 업으로 확대하는 방안을 모색하고 있다. 이를 위해 한부모가족지원법 등 한부모가정의 복지 지원정책을 살펴보고, 한부모가족지원법의 인권 신설조항을 바탕으로 한부모가정의 권익을 위해 한 부모가정 반편견교육을 교육현장에 제공하는 방안을 제시하고 있다. 한부모가 정 반편견교육은 아동의 편견과 차별의식을 줄여 가족에 대한 편견없는 사고 를 기를 수 있을 것으로 기대된다. This study points out that the government’s welfare policy for single-parent family merely remains at financial support such as subsistence benefit, and attempts to find a way of expanding policy coverage to include human right protection and promotion business for single-parent family. For this purpose, the study investigates the government’s welfare policy for single-parent family such as single-parent family support act, and suggests a plan for providing anti-bias education about the single-parent family in schools, based on new clause regarding human right in the single-parent family support act. The single-parent family anti-bias education is expected to contribute to nurturing prejudice-free thinking by reducing children’s prejudice and discrimination.

      • KCI등재

        일 대학병원 간호사의 간호기록 작성 지식과 중요도 및 수행도에 관한 연구

        황은숙,이소정,김신자,허인희 한국중환자간호학회 2019 중환자간호학회지 Vol.12 No.1

        Purpose : The purpose of this study was to assess hospital nurses' knowledge, importance and performance in keeping nursing records. Methods: The research design was a descriptive study. The sample for this study was 186 nurses with at least one year of work experience at a hospital with more than 800 beds in Seoul. Knowledge was self-reported using the Nurse Charting Knowledge Scale. Importance and performance were rated on a 4-point scale of 26 items. Data were analyzed by SPSS 21.0 program and IPA. Results: This study showed significant results that knowledge, importance and performance for keeping record are related to each other. The importance and performance of nurse's records were relatively higher than the mean. In the IPA Matrix, there were 2 items requiring improvement, 13 items requiring maintenance, and 11 items with low priority. Conclusion: Therefore, awareness of the importance of record keeping and continuous education on nursing record knowledge should be provided so that nurses can improve their record keeping skills.

      • 남성 뇌졸중 환자의 배뇨증상과 요정체 및 삶의 질

        황은숙 중앙대학교 의과대학 간호학과 간호과학연구소 2011 중앙간호논문집 Vol.15 No.-

        This study was done to examine the relationship beetween urinary symptom, urinary retention and quality of life in male patients hospitalized due to stroke. A cross-sectional descriptive correlational study was conducted in the C university hospital. Data were collected between April 1 and July 30, 2008 from 91 male stroke patients. the questionnaire included general items as well as items related to disease characteristics, a quality of life scale (Stroke-Specific Quality of Life, SS-QOL), and the international prostate symptom score (IPSS) for voiding symptoms. Urinary retention was measured using portable ultrasound scanning (CUBE scan, Biocon-500l 371458). The average age of the participants was 60.6 years old. Of the 91 participants, 75.9% had experienced their first stroke and 56% were diagnosed as having suffered cerebral infarction. Most of the participants (67%) were paralyzed on either one or both sides. The mean scores for the quality of life and urinary symptoms were 2.85±.85 and 14.71, respectively. Urinary urgency and nocturia were the most common symptoms. 67.1% of participants had moderate or severe urinary symptoms and 28.6% had urinary retention. Quality of life was negatively correlated with urinary symptom (r=-.870, p=.000_ and urinary retention (r=-.759, p=.000) and urinary retention (r=-.759, p=.000). Urinary symptom was positively correlated with urinary retention (r=.745, p=.000). The findings suggest that the efforts of nurses to recognize and manage the urinary symptoms and urinary retention of patients as early as possible will promote a better quality of life in hospitalized stroke patients.

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