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      • 울산공항의 항공기 운항에 따른 기상요소 분석

        허성일,오신범,이채욱 대구대학교 과학기술연구소 2001 科學技術硏究 Vol.8 No.1

        This paper identifies aircraft operations of Ulsan airport, analyzes factors for cause through weather elements, and explores the application of weather minima according to the directions of runway. Directions of the runway at Ulsan Airport consist of one, 18-36. The wind distribution is characterized by a northerly (N) wind direction that coincides with the runway direction (head and tail winds) while a southwesterly (SW) wind direction acts as a cross wind with the runway direction as a reference, requiring caution when an aircraft lands and takes off. The least visibility is prominent from May to June. In addition, due to topographical characteristics of the area, visibility obstruction from dense fog is frequent with the occurrence of radiation fog. But the effects of sea fog are almost non-existent. The analysis of weather elements at Ulsan according to aircraft operations is based on a fact that lowest weather minima have been set for run%vay, along with landing and take-off methods.

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      • KCI등재

        땅빈대 추출물의 항산화 활성 및 세포독성 효과

        허성일,호위성,한웅,왕명현 한국생약학회 2008 생약학회지 Vol.39 No.4

        The antioxidant activities, anti-inflammatory activity and cytotoxic effects of methanol extract from Euphorbia humifusa were evaluated in this study. Total phenolic compound contents were 68.35±0.16 mg/g and total flavonoid compound contents were estimated as 38.74±1.26 mg/g. EC50 values for DPPH radical scavenging activity of methanol extract was 56.26±0.66 μg/mL and those of positive controls as ascorbic acid, α-tocopherol and BHA were 8.38±0.14 μg/mL, 16.45±0.89 μg/mL and 21.18±1.01 μg/mL respectively. NO scavenging activity increased in depending on concentration of extract. Treatment of RAW 264.7 cells with extract caused inhibition of LPS-induced nitric oxide production. The cell viability showed that the methanol extract had cytotoxicity in the growth of breast cancer cell (66.54±1.91% at 400 μg/mL conc., 43.98±3.35% at 800 μg/mL conc.). Based on the results, It was suggested that the methanol extract of Euphorbia humifusa has a potential candidate for functional cosmetic and medicine.

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        민들레 추출물의 항산화 활성 및 세포독성 효과

        허성일,왕명현 한국생약학회 2008 생약학회지 Vol.39 No.3

        This study was investigated antioxidant and anticancer activity of water, methanol extract from upper and root part of Taraxacum mongolicum H. Total phenolic compound contents of methanol and water extracts from upper part were 51.95±0.18 mg/g and 48.16±0.89 mg/g respectively, and total flavonoid compound contents were estimated as 20.57±1.12 mg/ g in methanol extract and 6.55±1.20 mg/g in water extract. EC50 values for DPPH radical scavenging activity of methanol and water extract from upper part were 138.47±3.78 μg/mL and 204.38±5.32 μg/mL, and methanol and water extracts from root part were as 512±8.11 μg/mL in methanol extract and 1315.05±11.98μg/mL in water extract. Reducing power and hydroxyl radical (·OH) scavenging activity estimated that methanol extract of each part were higher than water extracts. The cell viability showed that the methanol extract from upper part had a cytotoxicity in the growth of colon carcinoma cell (44.58%). Both water extract (51.97±11.43%) from upper part and methanol (53.46±19.77%), water (52.79±13.53%) extracts from root part had quite higher cytotoxicity than that of methanol extract (88.25±2.02%) from upper part. Based on the results, It was suggested that the methanol extract of Taraxacum mongolicum H. were potential materials for use as functional food and medicine.

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        부위별 개쑥부쟁이(Aster ciliosus Kitamura)의 이화학적 성상 및 항산화 활성

        허성일,김영선,사재훈,심태흠,왕명현 한국생약학회 2005 생약학회지 Vol.36 No.3

        개쑥부쟁이의 생리활성 기능을 탐색하고 기능성 신물질을 개발하기 위하여 개쑥부쟁이의 부위별 즉, 꽃, 줄기, 뿌리로 나누어 화학성분, UV 흡광도 측정 및 항산화 활성을 조사하였다. 일반성분 분석은 부위별에 따라 다소 차이는 있으나 탄수화물 73~81%, 수분 11~15%, 조회분 4~7%, 조단백 2~6%, 조지방 1~4% 순으로 나타났다. 주요 무기성분은 Ca, K, Na, P로 나타났으며, 꽃에서 K이 가장 많았으며, 줄기와 뿌리에서는 Na이 가장 많은 것으로 나타났다. 주요지방산은 linoleic acid, palmitic acid, oleic acid, linolenic acid 으로 나타났으며, 포화 지방산(27~40%)에 비해 불포화지방산(59~72%)이 높게 나타났다. 구성당은 총 4종이 분리동정되었는데, glucose가 줄기>꽃>뿌리 순으로 보여주었고, xylose, galactose, arabinose순으로 나타났다. 페놀성 화합물의 함량은 280 nm에서 흡광도를 측정 결과 뿌리와 줄기의 chloroform 추출물에서 가장 높았고, 꽃과 뿌리의 ethanol 추출물과 뿌리의 75% ethanol 추출물에서 높게 나타났다. 또한 카로티노이드계 화합물은 꽃의 ethanol 추출물에서, 줄기의 chloroform 추출물에서 높게 나타났다. 항산화효과는 뿌리의 75% ethanol 추출물에서 가장 높았고, 뿌리의 ethanol 추출물과 꽃의 ethanol 추출물이 높은 항산화 효과를 나타내었다.

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        구체적 액수 산정이 불가능한 손해액 산정방법에 대한 판례 입장과 민사소송법 제202조의2의 활용방안 - 대법원 2004.06.24. 선고 2002다6951, 6968 판결을 중심으로 -

        허성일 고려대학교 법학연구원 2022 고려법학 Vol.- No.107

        Although the article 202-2 of the Civil Procedure Act was established in 2016 to allow a judge to determine the amount of damage in cases where it is recognized that damage has occurred but it is very difficult to prove the specific amount of damage due to the nature of the case, ‘Korea Supreme Court Decision 2002Da6951 and 6968 sentenced 24 June 2004’(“the Decision”) still has many meanings in terms of Principle of Disposition, Principle of Pleading and Principle of Free Evaluation of Evidence. First of all, although the original judgment of the lower court recognized the compensation for non-economic damages despite the plaintiff's claim for compensation for damages from non-performance of contract obligations, the Supreme Court construed that this lower court’s original judgment recognized, in fact, the compensation for damages from non-performance of contract obligation, not compensation for non- economic damages. However, in the sense that the subject-matter asserted by the parties in lawsuit and the subject-matter recognized by the lower court’s original judgment may be interpreted differently, this Supreme Court’s judgment has a possibility of controversy related to the Principle of Disposition, particularly, regarding the position traditionally has been maintained by the court that the compensation for non-economic damages is an independent subject-matter from the compensation for economic damages among the of subject-matter of lawsuit in the litigation for compensation for damages. In addition, when it comes to that, in this Supreme Court’s judgment, the court determined the amount of damage even though the parties have failed to clearly assert or prove the amount of damage, I believe there is also a possibility of controversy regarding the Principle of Pleading in which the parties have duties clearly assert or prove the amount of damage. Furthermore, the court calculated the amount of damage based on Principle of Free Evaluation of Evidence which is not a proper tool to c calculate the amount of damage. In this paper, by examining the detailed issues of the Decision regarding the Principle of Disposition, Principle of Pleading and Principle of Free Evaluation of Evidence, I tried to suggest that we may need to interpret that, the article 202-2 of the Civil Procedure Act is not merely to alleviate the degree of the judge’s heart condition, but to give the judge a specific discretion in calculating the amount of damage in case it is impossible to calculate the specific amount of compensation for damage.

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      • KCI등재

        Antioxidative Activities and Tyrosinase Inhibitory Effectsof Korean Medicinal Plants

        허성일,Mee-Jung Jung,Min-Kyeong Kim,왕명현 한국응용생명화학회 2007 Journal of Applied Biological Chemistry (J. Appl. Vol.50 No.3

        To discover the sources with antioxidant and tyrosinase inhibitory activities in Korean traditional medicines, 10 extract of medicinal plants were screened for their potential to scavenge stable 1,1diphenyl-2-picryhydrazyl (DPPH) free radical, inhibit hydroxyl radical (·OH), total phenolic content, and inhibition of tyrosinase. The potency of DPPH radical scavenging activity was shown in the extract of Ulmus davidiana var. japonica Nakai that has a greater effect with IC 50 values of 6 . 4 9 ± 5 . 4 3 µ g/mL, than BHA (IC 50 = 2 0 . 9 9 ± 0 . 7 4 µ g/mL), L-ascorbic acid (IC 50 = 2 0 . 5 9 ± 1 . 0 6 µ g/ mL), and α -tocopherol (IC 50 = 2 5 . 5 5 ± 0 . 2 6 µ g/mL) as a positive control. The ·OH scavenging activities were observed in the plants tested. Acanthopanax senticosus, Cirsium setiders, U. davidiana exhibited scavenging activity of more than 60% at 500 µ g/mL. The scavenging activity (%) of BHA and a-tocopherol were 64.32 and 55.87% at 500 µ g/mL, respectively. The total phenolic content was determined, in order to assess its effect on the extract’s antioxidant activity. The total phenoic c o n t e n t o f 3 3 . 3 7 ± 0 . 5 2 m g / g w a s c o n f o r m e d b y m e t h a n o l i c e x t r a c t o f U. davidiana . The U. davidiana and Morus bombycis e x h i b i t e d t y r o s i n a s e i n h i b i t o r y a c t i v i t y w i t h a 3 4 . 2 8 ± 1 . 3 2 a n d 7 5 . 5 7 ± 1 . 1 0 % , r e s p e c t i v e l y . I n p a r t i c u l a r , M. bombycis has stronger tyrosinase inhibitory activity t h a n a l b u t i n w i t h 3 6 . 4 8 ± 3 . 5 6 % a s a p o s i t i v e c o n t r o l . T h i s w o r k s h o w e d t h a t t h e i n h i b i t o r y abilities of Korean medicinal plants, such as U. davidiana and M. bombycis , on DPPH free radical, inhibit hydroxyl radical (·OH), and inhibition of tyrosinase and total phenolic content, can be useful in the prevention and treatment of free radical-relate disease. Investigations into further isolation of inhibitory principles of U. davidiana and M. bombycis are now in progress

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