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- 저자 : 하지홍 (검색결과 53 건)
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하지홍,정운복,이상로,탁연빈,김종봉 ( Ji Hong Ha,Woon Bok Chung,Sang Lo Lee,Ryun Bin Tak,Jong Bong Kim ) 한국유전학회 1991 Genes & Genomics Vol.13 No.4
The Sapsaree is a nearly extincted Korean native dog whose historic habitat has included much of the Southeastern Korea. The only existing population of Sapsaree consists of 50 dogs living in the small area of Kyung-San Goon in Kyung-Pook Province. Field observations of the population indicated the presence of two distinct morphological phenotypes that are divided into Blue- and Yellow-Sapsaree. A RFLP (Restriction Fragment Length Polymorphism) analysis using pV47-2 probe and Sapsaree DNA indicated the existance of two distinct genetic stocks concordant with the morphological phenotypes.
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광합성 세균 P-99 가 분비하는 항생물질의 구조 및 항암역가에 관한 연구
하지홍,오일웅 경북대학교 유전공학연구소 1992 遺傳工學硏究所報 Vol.7 No.1
The unidentified antibiotic P-99, produced by purple nonsulfur photosynthetic bacteria was selected by antimicrobial activity and reemergency. The compound was isolated from culture broth by solvent extraction followed by silica gel column chromatography. The compound was partially characterized and shown to be chiefly biologically active against gram-positive bacteria and melanoma cell line of SK-MEL-2.
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DNA Intercalating Agent 인 Ethidium Bromide 의 유전적 영향
하지홍,이세영,백형석,박찬규 한국유전학회 1980 Genes & Genomics Vol.2 No.1
The genetic effects of ethidium bromide on Salmonella typhimurium and Aspergillus nidulans were studied. Ethidium bromide was only weakly mutagenic on Salmonella typhimurium directly but upon the activation by the rat liver microsomal enzymes became highly mutagenic on the frameshift mutant of Salmonella typhimurium. Ethidium bromide was not mutagenic on Aspergillus nidulans directly or with the rat liver microsomal enzymes. However, it induced mitotic recombinations in the fungi in high frequencies.
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하지홍,정운복,이상로,탁연빈,김종봉 대구효성가톨릭대학교 자연과학연구소 1991 基礎科學硏究論集 Vol.1991 No.1
The Sapsaree is a nearly extincted Korean native dog whose historic habitat has included much of the Southeastern Korea. The only existing population of Sapsaree consists of 50 dogs living in the small area of Kyung-San Goon in Kyung-Pook Province. Field observations of the population indicated the presence of two distinct morphological phenotypes that are divided into Blue- and Yellow-Sapsaree. A RFLP (Restriction Fragment Length Polymorphism) analysis using pV 47-2 probe and Sapsaree DNA indicated the existence of two distint genetic stocks concordant with the morphological phenotypes.
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하지홍,이성은,탁연빈,김종봉 ( J . H . Ha,S . E . Lee,Y . B . Tak,J . B . Kim ) 한국축산학회 1998 한국축산학회지 Vol.40 No.6
The prototypes of physical characteristics in the breeds of Korean Native dog were reviewed. Sapsaree and Jindo dog were medium sized, but Sapsaree was 5 ㎏ heavier and 6 cm higher than Jindo dog on the average. The dominant coat color of Jindo dog and Chejudo dog was white or yellow, but that of Sapsaree was black or yellow. Sapsaree showed higher degree of variation in the tone of main color than Jindo dog. Most of the medium sized dog breeds in the Far East Asia had erect ears, upward tails and short coat. Jindo dog and Chejudo dog showed those characteristics of them, while Sapsaree had dropped ears and long coat. Appearance frequency of dew claw in Jindo dog and Chejudo dog was different from that in Sapsaree, the former was 4% and the latter was 18.3%. Fluctuations of blood cell number and blood protein contents were reviewed by different conditional variations such as age, sex and coat color in Jindo dog and Sapsaree. Blood types in DEA (dog erythrocyte antigen) system of the dog breeds showed extreme values that were different from the values of the European dogs. Phylogenetic relationships of the Asian dog breeds were compared by using the blood protein polymorphism. Jindo dog, Chejudo dog and Sapsaree showed close relationships among them.
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하지홍,김경석 ( J . H . Ha,K . S . Kim ) 한국축산학회 1998 한국축산학회지 Vol.40 No.6
The origin of Korean Native dog was studied by investigating the phylogenic relationships of Asian breed dogs. Polymorphic frequencies of 5 blood proteins of the breed, Hb(haemoglobin), Gmo(ganglioside monoxygenase). Es-2(esterase-2). Poa-2(post- albumin-3) and Ptf(pretransferrin) revealed that Sahalin and Eskimo dogs were the closest relatives to Korean native dogs. Polymorphic microsatellite loci analysis of 11 Asian native dogs also attested the same phylogenetic relationship of blood protein. Korean native dogs. Sapsaree. Jindo dog and Chejudo dog, formed a blood group and showed a close relationship with the Eskimo and Sahalin dogs. It was concluded that Korean native dogs were originated from the dogs of Northern part of Far East Asia from which Eskimo dog and Sahalin dog were also originated in the prehistoric age.
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유전 및 육종 / 한국 토종개 집단의 유전적 다양성과 구조
하지홍(J . H . Ha),이성은(S . E . Lee),김경석(K . S . Kim) 한국축산학회 1999 한국축산학회지 Vol.41 No.6
To investigate the genetic diversity and structure of Korean native dog populations, blood protein polymorphism, mtDNA sequence variation and microsatellite loci of them were analyzed. Blood protein polymorphism analysis was found to be useful for the understanding of genetic structure of the populations. However, the analysis of mtDNA sequence variation could not be used for the purpose. Microsatellite loci analysis showed the high values of heterozygosity and low values of genetic distances of Korean dog populations which were different from those of the Japanese and European dogs. Heterozygosity and average values of allele number of Jindo-dog, Akita dog and Grey hound were as follows ; 0.7 and 6.11 of Jindo-dog, 0.56 and 3.88 of Akita dog, 0.36 and 3.3 of Grey hound.
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