노인의 건강관심도와 심뇌혈관질환에 대한 지식 및 건강증진행위와의 관계

조정희,Cho, Jung Hee 한국가정간호학회 2021 가정간호학회지 Vol.28 No.2

Purpose: The purpose of this study was to find out the relationship between health concern, knowledge of cardio-cerebrovascular disease, and health-promoting behaviors among the elderly in the community. Method: The subjects of the study were 142 senior citizens aged 65 years or older in Cheongju-si, Chungcheong-do. Data were collected using structured questionnaires that included questions on the general characteristics, health concerns, knowledge of cardio-cerebrovascular disease, and health-promoting behaviors. The collected data were analyzed by the statistical program SPSS 20.0. The frequencies, percentages, averages, and standard deviations of the collected data were analyzed using a t-test, ANOVA, Mann Whitney U test, and Pearson's correlation coefficient, basing on the purpose of the study. The Scheffe test was carried out as a posteriori test. Result: The elderly were found to have a high health concern, but their knowledge of cardio-cerebrovascular disease was low, and their health-promoting behaviors were above the intermediate level. There was a significant positive correlation between each variable, which means that the higher the health concern was, the more knowledge an individual had of cardio-cerebrovascular disease, and the more health-promoting behaviors one had. Conclusion: This suggests that the elderly in the community should be encouraged to engage in the actions that promote their health by raising their level of health concern and awareness of diseases through health education, basing on their individual characteristics.

호흡에 따른 간장용적의 변화와 정상조직손상확율에 미치는 영향에 관한 연구

조정희,김주호,이석,박재일,Cho Jung Hee,Kim Joo Ho,Lee Suk,Park Je Il 대한방사선치료학회 2001 大韓放射線治療技術學會誌 Vol.13 No.1

Purpose: The aim of this study is to investigate geometrical and volumetrical changes of liver due to breathing and its impact to NTCP. In order to attain better treatment results it should be considered deliberately during planning session. Mehtods and Materials : Seven patients were examined in this study who have done TACE for accurate tumor margin drawing. After contrast media injection, C-T scan data were obtained in supine position during breathing free, inhalation and exhalation, respectively. For all patients C-T scan were done with same scanning parameters- 5 mm index, 5 mm thickness and pitch 1. Based on C-T data we have measured differences of each variables between breathing status such as changes of total and remained liver volumes, GTV, beam path length and superior to inferior shift. NTCP were calculated using Lyman's effective volume DVH reduction scheme and for this NTCP calculation, the V50 was computed from DVH and each m, n value were referred from Burmans data. Results : The measured total tilter volume and the remained liver volume changed between inspiration and expiration about $1.2-7.7\%(mean+2.7\%)$ and $2.5-13.23\%(mean=5.8\%)$ respectively, and these results were statistically significant(p>0.1). The GTV difference in each patient varied widely from $1.17\%\;to\;30.69\%$, but this result was not statistically significant. Depending on the breathing status, the beam path length was changed from 0.5 cm to 1.1 cm with the average of 0.7 cm, and it was statistically significant(p=0.006). The measured superior to inferior shifts were ranged from 0.5 cm to 3.74 cm. The NTCPs were changed relatively small in each patient, but the variation was large between the patients. The mean NTCP difference was $10.5\%$, with the variation ranged from $7\%\;to\;23.5\%$. Conclusion : Variations of liver volume and of beam path length were changed significantly depending on the breathing statues and the range of variation itself was very different between the patients. Since this variance could seriously affect the clinical outcomes of radiation treatments, the breathing of patients need to be accounted when a final treatment planning is derided.

전립선암 치료 시 Tomoimage에 기초한 Setup 오차에 관한 고찰

조정희,이상규,김세준,나수경,Cho, Jeong-Hee,Lee, Sang-Kyu,Kim, Sei-Joon,Na, Soo-Kyung 대한방사선치료학회 2007 대한방사선치료학회지 Vol.19 No.2

목 적: 방사선치료 중 환자의 자세나 해부학적 구조상 장기의 움직임과 치료 시 환자를 조준하면서 치료부위의 변화가 다양하게 발생할 수 있다. 이와 같은 요인은 종양부위나 정상조직에 대한 선량분포에 영향을 미치게 된다. 이는 치료계획용전산 화장비에 의해 계산된 선량이 실제임상 치료 시 서로 다른 선량이 조사될 수 있다. 인체의 생리학적인 움직임과 장기 내의 움직임 등은 고정기구나 정확한 환자의 치료준비에 의해서 치료조준의 정확성을 높일 수 있다. 본 연구의 목적은 토모영상을 통해 육안적종양체적(Gross tumor volume, GTV)과 장기의 치료 간에 발생하는 차이점을 평가하고자 한다. 대상 및 방법: 본원환자로서 직장풍선을 이용하여 치료하는 전립선암 환자 3명을 대상으로 하였고, 3달 동안 영상 자료를 수집 하였다. 각 환자마다 치료횟수 26회에 대한 토모영상을 획득하였고, 총 76회의 토모영상을 수집하였다. 각각의 토모영상은 전산화단층촬영모의치료(Computed tomography simulation, CT-simulation) 시의 중심점을 이용하였고, 매 치료 시 직장풍선에 60 cc의 공기주입 후 항문 가장자리에서 6 cm 깊이에 고정하여 전립선의 움직임을 고정시킨 후 치료 전에 토모영상을 획득하였다. 토모영상은 5 mm 두께로 영상을 획득하였다. 본 연구의 분석방법으로 CT-simulation와 MVCT (Megavoltage computed tomography, MVCT)의 융합을 위하여 납 볼을 이용하여, 토모치료의 3가지 영상융합방법으로 Bone technique, bone/tissue technique, full image technique을 이용하여 치료준비(setup)의 오차를 분석하였다. 영상융합은 눈에 보이는 납 볼 기준으로 융합하고, CT-simulation 시 획득한 영상에 MVCT에서 얻어진 영상을 융합하여, 뼈와 직장풍선, GTV을 매 치료 시 각각 비교하였다. 최초 CT-simulation 시 기준점을 중심으로 평균과 표준편차는 X, Y, Z, Roll에 대하여 각각의 환자를 분석하였다. 결 과: 분석결과 각각의 방법에 위해서 직장풍선의 변화는 확연히 다르게 나타났다. 정량적으로 뼈를 이용한 영상융합 결과 X방향으로 최대 8 mm, Y방향으로 4 mm의 움직임을 보였다. 직장풍선 기준으로 영상융합 한 결과 X, Y 방향으로 6 mm, 16 mm로 분석 되었다. 한 환자의 경우 16 mm 이상의 움직임을 보였는데, 이는 직장내의 공기나 분비물에 의한 움직임으로 분석 되었다. GTV 기준분석 결과 X 방향으로 2.7$\sim$6.6 mm, 4.3$\sim$7.8 mm가 Y방향으로 움직임을 보였다. 본 연구에서 Roll에 대한 분석결과 영상융합과 분석상에서 확연한 차이점은 없었다. 분석결과 뼈 기준의 분석결과 0.37$\pm0.36^{\circ}$, GTV 기준분석 결과 0.34$\pm0.38^{\circ}$의 회전을 보였다.

초기 개체군 밀도가 포식자-피식자 생태계 안정성에 미치는 영향

조정희,이상희,Cho, Jung-Hee,Lee, Sang-Hee 한국시뮬레이션학회 2013 한국시뮬레이션학회 논문지 Vol.22 No.3

생태계는 다양한 환경 내에 다양한 생물종이 서로 상호작용하고 있는 복잡계이다. 이들 상호작용은 계층적 먹이그물 구조를 이루고 있는데, 많은 경우, 포식자-피식자-식물의 관계를 보여준다. 포식자-피식자 경쟁관계는 시공간적으로 일어나는 현상이기 때문에, 초기시점에서의 개체들 분포와 밀도가 어떠한가는 매우 중요한 정보를 담고 있다. 본 연구에서는, 이들 세 단계 계층구조의 생태계를 간단한 격자 모델로 구성하고 이 모델을 사용하여 각 종의 초기 개체군 밀도가 변함에 따라 생태계 안정성이 어떻게 변하는지를 연구하였다. 격자공간은 $L{\times}L$ 크기의 L(=100) 사각격자로 구성되었다. 식물의 초기 밀도는 0.2로 고정하였다. 시뮬레이션 결과는, 포식자의 밀도가 0.4이하, 피식자의 밀도가 0.5이하일 때 두 종이 공존하는 것을 보여 주었으며, 포식자 밀도가 0.5이상, 피식자 밀도가 0.6 이상의 조건에서는 두 종이 멸종하는 것을 보여 주었다. 공존과 멸종의 두 상태가 접하는 영역의 조건에서는 확률적으로 공존하기도하고 멸종하기도 하는 비선형성이 강한 행동을 보여 주었다. 본 연구를 통해 초기종의 밀도가 생태계 안정성에 매우 중요한 역할을 한다는 것을 알 수 있었다. The ecosystem is the complex system consisting of various biotic and abiotic factors and the factors interact with each other in the hierarchical predator-prey relationship. Since the competitive relation spatiotemporally occurs, the initial state of population density and species distribution are likely to play an important role in the stability of the ecosystem. In the present study, we constructed a lattice model to simulate the three-trophic ecosystem (predatorprey- plant) and using the model, explored how the ecosystem stability is affected by the initial density. The size of lattice space was $L{\times}L$, (L=100) with periodic boundary condition. The initial density of the plant was arbitrarily set as the value of 0.2. The simulation result showed that predator and prey coexist when the density of predator is less than or equal to 0.4 and the density of prey is less than or equal to 0.5. On the other hand, when the predator density is more than or equal to 0.5 and the density of prey is more than or equal to 0.6, both of predator and prey were extinct. In addition, we found that the strong nonlinearity in the interaction between species was observed in the border area between the coexistence and extinction in the species density space.

인삼에 관한 생화학적 연구 ( Ⅳ ) 식이성 홍삼 증자수가 쥐에 주입한 ethanol 의 제거 속도에 미치는 영향

조정희,조용호,신상주 ( Jung Hi Cho,Yong Ho Cho,Sang Joou Shinn ) 생화학분자생물학회 1974 BMB Reports Vol.7 No.2

In the process of steam-dried ginseng manufacturing a quantity of aqueous by-product with a strong ginseng flavor is obtained and this by-product has been widely speculated for its commercial usage. When this by-product is added to a white liquor it smells and tastes like an ordinary commercial ginseng liquor. For these reasons the present experiment was conceived and carried out with rats to determine any effect of this by-product on the clearance rate of injected ethanol. It was found that this by-product did not influence the clearance rate of blood alcohol and had no more commercial value than other commercial soft drinks at most.

EPID의 적정관리 도구로서의 유용성에 관한 연구

조정희,방동완,윤성익,박재일,Cho Jung Hee,Bang Dong Wan,Yoon Seong Ik,Park Jae Il 대한방사선치료학회 1999 大韓放射線治療技術學會誌 Vol.11 No.1

Purpose : The aim of this study is to conform the possibility of the liquid type EPID as a QC tools to clinical indication and of replacement of the film dosimetry. Aditional aim is to describe a procedure for the use of a EPID as a physics calibration tool in the measurements of radiation beam parameters which are typically carried out with film. Method & Materials : In this study we used the Clinac 2100c/d with EPID. This system contains 65536 liquid-filled ion chambers arranged in a $256{\times}256$ matrix and the imaging area is $32.5{\times}32.5cm$ with liquid layer thickness of 1mm. The EPID was tested for different field sizes under typical clinical conditions and pixel values were calibrated against dose by producing images using various thickness of lead attenuators(lead step wedge) using 6 & 10MV x-ray. We placed various thickness of lead on the table of linear accelerator and set the portal vision an SDD of 100cm. To acquire portal image we change the field size and energy, and we recorded the average pixel value in a $3{\times}3$ pixel region of interest(ROI) at field center was recorded. The pixel values were also measured for different field sizes in order to evaluate the dependence of pixel value on x-ray energy spectrum and various scatter components. Result : The EPID, as a whole, was useful as a QA tool and dosimetry device. In mechanical check, cross-hair centering was well matched and the error was less than ?2mm and light/radiation field coincidence was less than 1mm also. In portal dosimetry the wider the field size the the higher the pixel value and as the lead thickness increase, the pixel value was exponentially decreased. Conclusions : The EPID was very suitable for QA tools and it can be used to measure exit dose during patients treatment with reasonable accuracy. But when indicate the EPID to clincal study deep consideration required

호흡에 따른 간장용적의 변화와 정상조직 손상확율에 미치는 영향에 관한 연구

조정희,김주호,이석,박재일,Cho Jung Hee,Kim Joo Ho,Lee Suk,Park Jae Il 대한방사선사협회 2001 대한방사선사협회지 Vol.27 No.2

Ⅰ. Purpose : The aim of this study is to investigate geometrical and volumetrical changes of liver due to breathing and its impact to NTCP. In order to attain better treatment results it should be considered deliberately during planning session. Ⅱ. Method

소조사면 전량분포의 특성에 관한 고찰

조정희,이상규,안승권,박재일,Cho JeongHee,Lee SangKyu,An SeungKwon,Park Jell 대한방사선치료학회 2004 大韓放射線治療技術學會誌 Vol.16 No.1

목적 : 본 연구의 목적은 소조사면의 선량특성을 측정하며 콜리메이터의 위치에 따른 반음영의 변화와 중심선량의 분포양상을 측정하며 측외측정선량점의 변화에 따른 선량분포의 특성을 측정하여 최근 대두되고 있는 소조사면 방사선치료에 유용한 정보를 제공하는데 그 목적이 있다. 대상 및 방법 : 지멘스의 Primart 선형가속기의 6MV에너지를 이용하였으며 측정은 Farmer chamber와 Pinpoint chamber를 이용하여 심부선량율과 beam profile, 중심출력선량의 변화를 측정하였다. 중심선속의 변화에 따른 에너지의 특성과 반음영의 변화를 외측으로 2cm 간격으로 측정하였다. 측정은 $1{\times}1cm,\;3{\times}3cm,\;5{\times}5cm,\;10{\times}10cm$에서 측정하였으며 결과는 표준조건하의 측정값과 비교, 분석하였다. 결과 : Farmer chamber와 Pinpoint chamber를 이용해 $1{\times}1cm$, 10cm깊이에서 측정한 결과 두 측정기간에 소조사면에서는 $30\%$ 이상의 차이를 보였으며 조사면의 크기가 증가함에 따라 두 측정기간의 차이는 급격히 감소했다. 측외측정점의 변화에 따른 선량분포는 큰 차이가 없었으나 조사야의 크기가 감소함에 따라 $1{\times}1cm$에서는 약 $13\%$의 차이를 보여 조사야 크기에 따른 변화가 큰 것으로 측정되었다. 전체조사면에서 반음영이 차지하는 비율도 조사면이 적어짐에 따라 높게 나타났으며 $1{\times}1cm$의 조사면에서는 약 $50\%$가 반음영이 점유하는 것으로 측정되었다. 결론 : 세기조절방사선 치료를 위해서는 각기 다른 에너지 분포를 갖는 여러 각도에서 다수의 조사면를 필요로 하며 여러 복잡한 인자들이 관여하게 된다. 여러 인자들 중에서도 콜리메이터의 형태 및 위치에 따른 출력선량의 변화 양상을 정확히 측정하는 것은 매우 중요하다. 실험결과에서도 알 수 있듯이 측정깊이와 조사면의 크기 및 측정기의 종류에 따른 측정값의 변화가 매우 크게 나타나므로 양질의 세기조절방사선 치료를 제공하기 위해서는 특히 소조사면의 선량분포에 대한 특성을 정확히 측정하는 것이 매우 중요하다. Purpose : The aim of this study is to investigate the properties of small field size and to measure the penumbra and central axis depth dose varying to the jaw setting and off axis distance for indicate this data to small field sizes radiation therapy. Material and methods : The percentage depth dose, beam profile and central axis output dose was measured by farmer type ion chamber and pinpoint chamber using Primart linac with 6MV energy. Beam quality and penumbra variations according to the central axis shift, from center to every 2cm outside increment, and field size, from $1{\times}1cm$ to $10{\times}10cm$ was investigated and compared with that of the standard geometrical condition's results Results : The differences of measured values between two ion chamber was about $37\%$ at 10cm depth with $1{\times}1cm$ field sizes but as field size increased this differences was diminished gradually. Measured data from various off axis distance with the different asymmetric collimations are not changed significantly but as size decreased the dose variation was increased and at $1{\times}1cm$ field size dose difference among off axis distance was as much as $13\%$, and as shallower the measured depth the central axis dose variations among the OAD was increased, penumbra was not changed noticeably depending on off axis distance but the percentage of penumbra from its initial field sizes was strongly dependant on field sizes and penumbra occupation rates of its own field sizes ranging from $6\%$ at $10{\times}10cm$ to $50\%$ at $1{\times}1cm$ field size. Conclusion : For imrt treatment, there are several numbers of different gentry angles with beams of nonuniform fluences are required and several complex factors involved. Among them the characteristics of beam output varying to the geometrical setting and design of collimators are of important to attaining a good treatment results. As mentioned in results the differences of measured values are changed significantly depends on ion chamber volume, depths and field size. For providing quality radiation treatment, especially at small field size, those factor's should have considering deliberately.

사용 편의성과 소형화 기반의 맥파 측정장치 개발

조정희,배장한,김영민,전민호,양태헌,전영주,Cho, JungHee,Bae, JangHan,Kim, YoungMin,Jun, MinHo,Yang, TaeHeon,Jeon, YoungJu 대한의용생체공학회 2017 의공학회지 Vol.38 No.4

To improve and downsize the KIOM-Pulse Analysis System(KIOM-PAS), which has been traditionally used in clinical trials, a miniaturized PAS(M-PAS) with a pneumatic pump has been developed. M-PAS is composed of a measurement module and an arm-mounting module, on which an arm can be placed. The measurement module is equipped with a pressing component and sensor, which is a wearable wristband. The arm-mounting module includes a pneumatic motor, data acquisition board and valves. In addition, the measurement module is divided into a fixing module of band type for attachment to a pulsation site and a sensing module, which includes a sensor and a tube. The fixing module and sensing module are constructed independently, and the detachable fastening method improves the posture convenience of the subject during measurement. M-PAS has been reduced to 1/6 the size of KIOM-PAS, and the measurement time is shortened by 22%. Using a simulator, the difference between the waveforms measured by the two devices exhibited a high degree of similarity of within 3.65%. M-PAS represents improvements in size and convenience compared with KIOM-PAS, and it is expected to be widely used in clinics in the future because it improves the attachment method of the fixing module.

Biochemical Studies on Ginseng(IV) Effect of Dietary Intake of of Aqueous Red Ginseng By-product on Clearance Rate of Injected Ethanol in Rats

조정희,조용호,신상주,Cho, Jung-Hi,Cho, Yong-Ho,Shinn, Sang-Joou 생화학분자생물학회 1974 한국생화학회지 Vol.7 No.2

In the process of steam-dried ginseng manufacturing a quantity of aqueous by-product with a strong ginseng flavor is obtained and this by-product has been widely speculated for its commercial usage. When this by-product is added to a white liquor it smells and tastes like an ordinary commercial ginseng liquor. For these reasons the present experiment was conceived and carried out with rats to determine any effect of this by-product on the clearance rate of injected ethanol. It was found that this by-product did not influence the clearance rate of blood alcohol and had no more commercial value than other commercial soft drinks at most. 수삼을 중좌하여 홍삼을 제조하는 과정 중 다량의 증자수가 얻어진다. 이 수용액은 강한 인삼 향기를 지녔으며 따라서 그 상품화가 모색되고 있다. 그런데 이 수용액을 소주에 첨가하면 그 맛이 보통 인삼주와 갈아진다. 따라서 본 연구는 이 물질이 ethanol을 주입한 쥐의 ethanol 제거 속도에 대하여 어떤 효과가 있는지 규명하는데 그 목적이 있다. 실험결과 이 물질은 혈액 ethanol의 제거에는 아무 영향도 미치지 않으며 따라서 이 물질은 다른 시판 음료수와 별 차이가 없다는 결론을 짓게 한다.