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기관지천식 환자에서 말초 혈액 단핵구와 기관지폐포 세척액 세포의 IL - 4 유전자 표현
이상무(Sang Moo Lee),문승혁(Seung Hyuk Moon),김경호(Kyung Ho Kim),임건일(Gune Il Lim),정성환(Seong Whan Jeong),김현태(Hyeon Tae Kim),어수택(Soo Taek Uh),김용훈(Yong Hoon Kim),박춘식(Choon Sik Park) 대한내과학회 1996 대한내과학회지 Vol.50 No.1
N/A Objectives: Type 2 CD4+ lymphocytes are presumed to have an important role in develompent of allergic inflammation. We measured m-RNA expressions of interleukin 4 in peripheral blood mononuclear cells and bronchoalveolar lavage cells to investigate the difference of interleukin 4 gene expression in the patients with atopic and nonatopic bronchial asthma, normal subjects and patients with other lung disease. Methods: Total RNA was obtained from peripheral blood mononuclear cells and bronchoalveolar lavage cells by acid-guanidium thiocyanate-phenol-chloroform method. The presence of interleukin 4 m-RNA was identified by RNA reverse transcription/polymerase chain reaction. Southern blot or DNA dot blot was applied to confirm the interleukin 4 gene products. Results: Interleukin 4 Gene products in peripheral blood mononuclear cells were detected in 90.9% (10/11) of the patients with bronchial asthrna and in 75%(9/12) of non-asthmatic control subjects. Interleukin 4 gene product in bronchoalveolar lavage cells was positive in one case of bronchial asthma. Conclusion: Interleukin 4 m-RNAs were constitutionally expressed in peripheral blood mononuclear cells of normal controls as well as in those of the patients with bronchial asthma
폐기능이 저하된 폐암환자에서 폐절제술후 합병중의 예측인자 평가에 관한 전향적 연구
박정웅 ( Jeong Woong Park ),정성환 ( Sung Whan Jeong ),남귀현 ( Gui Hyun Nam ),김호철 ( Ho Cheol Kim ),서지영 ( Gee Young Suh ),정만표 ( Man Pyo Chung ),김호중 ( Ho Joong Kim ),권오정 ( O Jung Kwon ),이종헌 ( Chong H. Rhee ) 대한결핵 및 호흡기학회 2000 Tuberculosis and Respiratory Diseases Vol.48 No.1
ERBD 후 배액관 기능 평가에 대한 초음파촬영술의 의의
이문성(Moon Sung Lee),황효주(Hwo Joo Hwang),정성환(Seong Whan Jeong),김진홍(Jin Hong Kim),조성원(Sung Won Cho),심찬섭(Chan Sup Shim) 대한내과학회 1989 대한내과학회지 Vol.37 No.4
N/A Nonsurgical drainage of alignant obstructive jaundice is an interesting altenative to surgical drainage in the palliative treatment of pancreaticobiliary neoplasm. Biliary drainage by endoprosthesis is as effective and better supported than percutaneous external drainage, but more hard difficult to control. Forty-two cases with biliary or pancreatic carcinoma treated by endoprosthesis, ERBD, were followed up by ultrasonogram. Ultrasonic monitoring was useful in the demonstrations of the effectiveness of drainage and the detection of the endoprosthetic dysfunction. Consequently the ultrasonogram may be considered as a valuable method to complement the biochemical tests in the monitoring of biliary endoprosthesis.
전통문화 교육을 위한 아동 교구디자인 및 교육프로그램 연구
허은정 ( Eun Jeong Hoe ),정수경 ( Su Kyoung Jeong ),정성환 ( Sung Whan Chung ) 한국기초조형학회 2014 기초조형학연구 Vol.15 No.3
한국은 고도로 발달된 현대 서구 문명과 문화의 무분별한 유입 및 모방으로 전통문화의 단절과 함께 정체성 혼란의 위기를 초래하였다. 이러한 문제점들이 부각되면서 우리나라 역시 전통문화를 보존·계승하고 이를 활용할 수 있도록 다양한 시도를 하고 있으며, 이러한 관심과 이해가 지속될 수 있도록 하기 위해서는 교육이 전제되어야 한다. 이에 본 연구는 아동이 전통문화를 자연스럽게 경험하고, 창의성 증진에 효과적인 교구를 제작하여 이에 대한 효과를 극대화할 수 있는 프로그램을 개발하고 제안하는데 목적이 있다. 현재 전수교육관에서 교육을 진행 중인 전수자와 함께 종목을 선정하고 각 종목별로 교육, 디자인 등의 전문가그룹을 구성하여 교구디자인에 대한 세부 프로세스를 진행하였다. 단청은 문양을 맞출 수 있는 퍼즐, 자수는 타공판을 이용한 자수판과 도구, 목조각은 플라스틱 조각도와 신소재를 이용한 시연 점토판, 선소리 산타령은 일러스트를 사용한 플래시카드를 완성하였다. 이는 아동과 종목의 특성을 고려하여 제작하였으며 안전성, 심미성, 난이도, 재미·흥미 등을 반영하였다. 프로그램은 문양 맞추기, 기초 기법 배우기, 가사 순서 맞추기 등 종목의 특성을 배우는 기본 프로그램과 교구를 통해 다양하게 표현하고, 만들며, 게임을 할 수 있는 심화 프로그램으로 구성하였다. 이후 하나의 종목을 시범교육 한 결과 교육 만족도와 필요성에 대한 인식도가 높게 나타났다. 본 연구는 종목선정에 있어 연구범위가 다소 제한적이었지만, 향후에는 최소한의 연구범위를 적용하고 제작한 모든 교구의 시범교육을 통해 전통문화 이해도와 창의성 향상에 대한 검증이 필요하다. Korea caused confusion in identify along with traditional culture discontinuation as advanced and developed western culture and civilization inflows and are copied imprudently. As these problems appear, our country also tries in different ways to apply, preserve, and succeed this kind of traditional culture. To make this kind of interest and understanding persisting, education must be a premise. Therefore, this study aims to suggest developing programs which can maximize effect of efficient educational tools for creativity and make children experience traditional culture naturally. With an initiator who educates at succession education institute, items were selected and detailed processes were undergone for tool designs by grouping professional groups for education, design, etc. Dancheong is a puzzle which matches patterns. Embroidery is tool, and embroidery board. Wooden Sculpture are practical clay board by using plastic gravers and new materials, and Seonsori Santaryeong completed flash card by using flash card. Considering the features of children and types, they were produced. They reflected stability, esthetic feature, difficulty, interest/fun, etc. Programs express basic programs and educational tools differently such as pattern matching, basic methods study, lyric order matching, etc. They were made differently. Advanced programs were composed to play games. As a result of educating one item as an example, awareness of educational satisfaction and necessity appeared high. The range of minimal study was applied. Through manufactured educational tools’ model education, verification on understanding level about traditional culture and creativity improvement is required.
국내 폐 랑게르한스세포 조직구증(Pulmonary Langerhans Cell Histiocytosis)의 임상양상
김철 ( Chul Kim ),정성환 ( Sung Hwan Jeong ),심재정 ( Jae Jeong Shim ),차승익 ( Seung Ick Cha ),손춘희 ( Choon Hee Son ),정만표 ( Man Pyo Chung ),박혜윤 ( Hye Yoon Park ),김영환 ( Young Whan Kim ),박종선 ( Jong Sun Park ),어수택 대한결핵 및 호흡기학회 2009 Tuberculosis and Respiratory Diseases Vol.66 No.2
Background: Pulmonary Langerhans cell histiocytosis (PLCH) is characterized by a proliferation of Langerhans cells and this results in granulomas that involve multiple organs of the body. Because the incidence of PLCH is very low in Korea and worldwide, collecting the clinical data of patients with PLCH nationwide is needed to determine the clinical features of Korean patients with PLCH. Methods: The patients with PLCH confirmed by biopsy at any body site were included and the patients should have lung lesions present. A questionnaire that had items on the symptoms, lung function tests, the roentgenographic findings and the treatment was collected retrospectively at a Korean ILD Research Meeting. Results: A total of 56 cases were collected. The number of males and females was 48 and 8, respectively, and their median age was 43 years (range: 18∼67 years). The patients were current or ex-smokers in 79% of the cases. The most frequent symptom was coughing (39%), followed in decreasing order by dyspnea (38%), sputum (20%) and chest pain (20%). Pneumothorax was observed in 16 (29%) patients. Lung function tests showed a normal, restrictive, mixed or obstructive pattern in 26 (61%), 7 (16%), 7 (16%) and 3 patients (7%), respectively. Nodular-cystic lesion was most frequently observed in 59% of the patients on HRCT. The lung lesions were located in the middle and upper lobes in almost the cases. The median follow-up period was 90 months (range: 1∼180 months) and only two patients died during this period. Conclusion: This study provides a national survey of the patients with PLCH during a long follow-up period.
원발성 Bronchiolitis Obliterans Organizing Pneumonia 1 예
최영수(Young Soo Choi),이광희(Kwang Hee Lee),정성환(Seong Whan Jeong),이상무(Sang Moo Lee),김현태(Hyeon Tae Kim),어수택(Soo Taek Uh),김용훈(Yong Hoon Kim),박춘식(Choon Sik Park),진소영(So Young Jin),이동화(Dong Hwa Lee),박재성(Jai So 대한내과학회 1995 대한내과학회지 Vol.48 No.5
N/A Bronchiolitis obliterans organizing pneumonia (BOOP)is a type of diffuse or focal infiltrative lung disease characterized by granulation tissue plugs within lumens of small airways and extending into alveolar ducts and alveoli. Only three cases of BOOP were reported in Korea, in spite of many cases of BOOP were reported in the world. We report here one case of idiopathic BOOP in 32-years-old female who complain dyspnea and flu-like illness those managed successfully by conservative treatment.
남궁선(Sun Nam-Goong),이유리(Yuri Lee),정수경(Su-Kyoung Jeong),정성환(Sung-Whan Jeong) 한국가구학회 2010 한국가구학회지 Vol.21 No.2
As the contemporary lifestyle has changed and the time to enjoy hobbies is increased. people prefer the DIY furniture that can be used at homes by manufacturing their own unique furnitures. Especially, the architecture of our country handed down traditionally or the setting-up technique used in furnitures are the techniques to maintain firmness even after long time passes by. Accordingly, in order to supply a firm setting-up technique mostly used by craftsman in the manufacture of DIY furniture and to apply this easily, a web site and 3D program system are required. In order to do so, it is important to prepare the system of setting-up that can be followed easily first by classifying the difficulty of setting-up that the general public can follow easily without having difficulties among the types of setting-up. Therefore, this study has performed a systematic arrangement by the order of difficulty for the types of setting-up that are investigated and arranged to set the purpose as presenting materials that are helpful so the furnitures using setting-up can be manufactured even in the manufacture of general DIY furnitures, Accordingly, the investigated results of setting-up difficulty are applied in the order of difficulty to a 3D program and as users select the suitable setting-up for their own standard, it is expected to be utilized in DIY furnitures that are manufactured directly.
Interleukin-2가 호산구 생존에 미치는 영향과 기전에 관한 연구
김효석 ( Hyo Seok Kim ),이영목 ( Young Mok Lee ),최영수 ( Young Soo Choi ),김경호 ( Kyung Ho Kim ),임건일 ( Geon Il Im ),문승혁 ( Jeong Sung Whan ),정성환 ( Moon Seung Hyug ),김현태 ( Hyeon Tae Kim ),어수택 ( Uh Soo Taek ),김용훈 대한결핵 및 호흡기학회 1996 Tuberculosis and Respiratory Diseases Vol.43 No.3