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정상인의 Propionibacterium acnes에 대한 균체응집항체와 ABO 동종혈구응집항체간의 민감성
전호진,최철순,양용태 중앙대학교 의과대학 의과학연구소 1982 中央醫大誌 Vol.7 No.1
Some of the clinocal features such as chronic infections, recurrent infections and incomplete responses to chemotherapy often provide an important clue to establish antibody (B cell) immunodeficiency diseases mainifest. Early diagnosis of hypogammaglobulinemia or demostration of marked deficiency of immunglobulin in the patients who have such clinical features is of utmost importance in the management or treatment of patients with administration of either gamma-globulin or specific immunoglobulins. A number of screening tests have been recently developed in the diagnosis of specific immunodeficiency disorders. Among the functional evaluation of antibody-mediated immunity aer protein electrophoresis, radial immunodiffusion test, Schick test, isohemagglutinin test, specifc antibody response and B cell quantitation. A demostration of either isohemagglutinin which resultedfrom immunization with natural A and B substances or bacterial agglutinins to Propionibacterium acnes which comprises the predominant resident flora of the skin may be useful since they would provide immediate results without any specific immunizations onto the patients. However, as a screening test of antibody-mediated immunity in healthy individuals, the significance of isohemagglutinin in test and bacterial agglutination test with P. acnes has not been evaluated for their sensitivities. In this study, titres of isohemagglutinin(IgM class) and bacterial agglutinins to P. acnes(IgG class) were measured among ABO blood groups by means of microtitration technique. In the sera of O group, anti- A isohemagglutinin titre ranged from log₂1(25.0%) to log₂8(8.3%) and its mean titre was log₂3.41 2.22, and anti-B isohemagglutinin titre ranged from log₂1(41.6%) to log₂5(16.6%)and its mean titre was log₂2.40±1.40, and bacterial agglutinin titre to P. acnes ranged from log₂4(20.2%) to log₂7(20.0%) and its mean titre was log₂5.60±1.04. In the B group, anti A isohemagglutinin titre ranged from log₂1(16.6%) to log₂4(33.3%)and its mean titre was log₂2.66±1.15, and bacterial agglutinin titre aganist P. acnes ranged from log₂5(16.6%) to log₂7(33.3%)and its mean titre was log₂6.16±0.71. In the AB blood group, bacterial agglutinin titre ranged from log₂3(16.6%) to log₂8(16.6%)and its mean titre was log₂5.58±1.28. In the O blood group, anti-A titre was greater than anti-B titre(P<0.05). There were no significamt differences in anti-A titres between O and B groups and in anti-B titres between O and A group. Bacterial agglutinin titre of O group was higher than those of A group(P<0.05) and AB group(P<0.01). Isohemagglutinin titre(IgM class) and bacterial agglutinin titre(IgG class) showed no correlation in the microtitration system. These results indicate that bacterial agglutinins to P.acnes(IgG class)is higher than Isohemagglutinin(IgM class) in normal human serum but both tests may be useful independently for selective immunoglobulin deficiency test.
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전호진,김영민 한국국제상학회 2019 國際商學 Vol.34 No.1
Purpose : We analyze the impact of logistics performance based on logistics performance index on national competitiveness, and suggest strategic implications for logistics to improve national competitiveness. Research design, data, methodology : To analyze the impact logistics performance(customs, infrastructure, international shipping, logistics competence, tracking and tracing, and timeliness) of the World Bank on the global competitiveness(basic requirements, efficiency enhancers, and innovation and sophistication factors), multiple regression analysis was performed. Results : Logistics performance such as customs, infrastructure, tracking and tracing had a significant positive impact on national competitiveness. Conclusions : The logistics performance of a country not only has a limited impact on trade and logistics but also has a great impact on national competitiveness as a whole. In the situation where countries around the world are looking for various ways to enhance their competitiveness, improvement of logistics performance, logistics efficiency and logistics competitiveness should be given priority as means to enhance the national competitiveness in the long term. 물류성과지수를 기준으로 한 국가의 물류성과가 국가경쟁력에 미치는 영향을 분석하고, 국가경쟁력 향상을 위한 물류 측면에서의 전략적 시사점을 제시하고자 하였다. 세계은행의 물류성과지수(통관, 인프라, 국제운송, 물류 역량, 화물추적시스템 및 적시성)를독립변수로 하고 세계경제포럼의 국가경쟁력지수(기본 요소, 효율성 증진 요소 및 혁신과 정교화 요소)를 종속변수로 하여 다중회귀분석을 실시하였다. 연구 결과, 통관, 인프라 및 화물추적시스템과 같은 물류성과가 국가경쟁력에 유의한 양(+)의 영향을 미치는 것으로 나타났다. 한 국가의 물류성과는 단순히 무역 및 물류 등에만 제한적으로 영향을 미치는 것이 아니라국가 전체의 경쟁력을 향상시킬 수 있을 뿐만 아니라 그 영향력이 매우 높다고 할 수 있다. 세계 각 국가가 자국의 경쟁력 제고를 위해 다양한 방안을 모색하고 있는 상황에서 장기적인 국가경쟁력 제고를 위한 방안으로 무엇보다 물류성과의 향상, 물류 효율성 개선, 물류 경쟁력 제고가 우선되어야 할 것이다.
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