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      • KCI등재

        전정신경염에서 추골동맥 병변의 임상적 의의

        전현웅,정재호,이승환,변하영,김병훈,박민규 대한이비인후과학회 부산,울산,경남 지부회 2022 임상이비인후과 Vol.33 No.3

        Background and Objectives: The etiology of vestibular neuritis (VN) is elusive, however viral infection and vascular ischemia are considered as major cause of VN. The aims of the present study were to evaluate relationships between vertebrobasilar artery status and VN. Materials and Methods: Patients who received treatment for VN from April 2014 to October 2019 were enrolled. All subjects underwent vestibular function tests of caloric test, cervical vestibular evoked myogenic potential test and magnetic resonance imaging (MRI) angiography. Vertebral artery (VA) lesions were defined as vertebral hypoplasia and vertebral stenosis. Results: A total of 130 patients were diagnosed as VN and completed MRI angiography. 12 patients had VA abnormalities (9.23%). 9/12 patients (75.0%) had same lesion side of VN and VA lesions (p=0.098). Hospitalization period, duration of dizziness and duration of spontaneous nystagmus between normal VA group and abnormal VA group had no significant difference. However, duration of spontaneous nystagmus considering only abnormal caloric test group was significantly lower in abnormal VA group than normal VA group (p=0.001). Conclusion: The present study suggested that VA disorder might have relationship with VN, as vascular factor is one of the most common reasons for VN. Moreover, spontaneous nystagmus recovers faster in patients with VA disorder.

      • KCI등재

        가시광선하에서 CdS와 CdZnS/ZnO 광촉매를 이용한 로다민 B, 메틸 오렌지 및 메틸렌 블루의 광분해 반응

        전현웅(Hyun Woong Jeon),정민교(Min Gyo Jeong),안병윤(Byeong Yun An),홍민성(Min Seong Hong),성상혁(Sang Hyeok Seong),이근대(Gun Dae Lee) 한국청정기술학회 2020 청정기술 Vol.26 No.4

        본 연구에서는 단순 침전법으로 제조한 CdS 및 CdZnS/ZnO 광촉매를 이용하여 가시광선하에서 로다민 B, 메틸 오렌지 및 메틸렌 블루 등에 대한 광분해 반응 연구를 수행하였다. 특히 염료와 광촉매의 물리화학적 성질이 전체 광촉매 반응의 반응 경로에 미치는 영향에 대해 중점을 두고 검토하였다. X선 회절분석법, UV-vis 확산반사 분광법 그리고 X선 광전자 분광분석법 등을 이용하여 제조된 촉매들의 물리화학적 특성을 분석하였다. CdS 및 CdZnS/ZnO 광촉매 모두 자외선뿐만 아니라 가시광선 영역에 있어서도 우수한 광흡수 특성을 나타내었다. 메틸 오렌지의 경우에는 CdS 및 CdZnS/ZnO 각각의 광촉매 상에서 동일한 반응기구를 통해 반응이 진행되는 반면, 로다민 B 및 메틸렌 블루는 각각의 광촉매 상에서 서로 다른 반응 경로를 통해 광분해 반응이 진행되는 것으로 나타났다. 특히 메틸렌 블루의 광분해 반응을 보면, CdZnS/ZnO 광촉매 상에서는 주로 단일분자 형태로 전체 반응이 진행되지만, CdS 상에서는 반응 초기부터 이량체를 형성하였다. 이와 같은 결과들은 CdS 및 CdZnS/ZnO 각각의 반도체 광촉매들의 전도대의 띠끝 전위 차이와 염료들의 흡착 특성 차이에 기인한 것으로 판단된다. In this study, the photocatalytic degradation of rhodamine B (RhB), methyl orange (MO) and methylene blue (MB) was carried out under visible light irradiation using CdS and CdZnS/ZnO photocatalysts prepared by a simple precipitation method. This study focused on examining the effect of physicochemical properties of dye and photocatalyst on the reaction pathway of photocatalytic degradation. The prepared photocatalysts were characterized by XRD, UV-vis DRS and XPS. Both the CdS and CdZnS/ZnO photocatalysts exhibit an excellent absorption in the visible light and the UV light regions. It was observed that the photocatalytic degradation of MO proceeds via the same reaction mechanism on both the CdS and CdZnS/ZnO photocatalysts. However, the photocatalytic degradation of RhB and MB was found to proceed through a different reaction pathway on the CdS and CdZnS/ZnO catalysts. It is interesting to note that MB dimer was formed on the CdS catalyst at the beginning of the photocatalytic reaction, while the MB monomer was degraded during the overall photocatalytic reaction on CdZnS/ZnO. The above results may be mainly ascribed to the difference of band edge potential of the conduction band in the CdS and CdZnS/ZnO semiconductors and the adsorption property of dye on the catalysts.

      • KCI등재후보

        악하부 농양으로 발병한 육아종증 다발 혈관염 1예

        전현웅(Hyun Woong Jun),홍성만(Seong Man Hong),정진혁(Jin Hyeok Jeong),지용배(Yong-Bae Ji) 대한두경부종양학회 2023 대한두경부 종양학회지 Vol.39 No.1

        Granulomatosis with polyangiitis (GPA), formerly known as Wegener’s granulomatosis, is a rare immunological small vessel disease which usually affects respiratory tract and kidneys. However, salivary gland involvement in GPA is rare as a primary manifestation. We report a case of GPA with the primary presentation of submandibular gland involvement. A 48-year-old female patient presented submandibular swelling with a skin defect that lasted for 1 month. Although the biopsy result was chronic inflammation, the skin defect did not heal for a month. Further imaging study revealed multiple lung and renal masses. More clinical manifestations such as gingivitis, ischemic change of finger joint and nasal tip skin, and positive c-ANCA test was presented. Additional biopsy was made at the submandibular gland, lung, and finger skin. The patient was finally diagnosed with GPA and treated with steroid pulse therapy and cyclophosphamide. The patient showed improvement of prior clinical symptoms.

      • KCI등재

        인후두 역류질환에서 양성자 펌프 억제제 치료가 삶의 질에 미치는 영향

        최해원,전현웅,정진혁,김무건,태경,지용배 대한이비인후과학회 2020 대한이비인후과학회지 두경부외과학 Vol.63 No.11

        Background and Objectives Several studies have assessed the impact of laryngopharyngealreflux disease (LPRD) on the health-related quality of life (HR-QoL), showing significantimpairment of HR-QoL. This study aims to assess the impact of proton pump inhibitor (PPI)treatment of LPRDs to enhance HR-QoL. Subjects and Method We prospectively collected data from LPRD patients from April2017 to July 2019. Patients who have reflux symptom index (RSI) of ≥13 or reflux findingscore (RFS) of ≥7 were enrolled in this study. We assessed HR-QoL using a questionnairewith EORTC QLQ-H&N35, -C30 on the first visit. Patients were treated with PPI (Ilaprazole20 mg/day) on their visits at 4, 8, and 12 weeks. RSI and RFS were measured at each visit andHR-QoL was reevaluated on the last visit. Results Ninety-five patients completed the 3-months follow-up and were enrolled in thisstudy. Female : male ratio was 71:24 and the mean age was 57.0±11.9 (27-80). The initial RSIand RFS were 16.3±8.8 and 12.6±2.9, respectively, but were changed to 11.1±9.7 and 9.7±2.6(p<0.001 in both) at 12 weeks after the treatment. Global health status/QoL, speech problem,dry mouth, and coughing were significantly improved. Conclusion PPI administration is effective in treating LPRD, where effects begin to appear at4 weeks after treatment. HR-QoL was also improved in patients who have RSI improvement.

      • KCI등재

        재발성 양성 돌발성 체위성 현훈의 위험인자와 임상적 특성

        김무건,김희령,전현웅,변하영,정재호,이승환 대한이비인후과학회 2019 대한이비인후과학회지 두경부외과학 Vol.62 No.10

        Background and Objectives Benign paroxysmal positional vertigo (BPPV) is treated withappropriate canalith repositioning procedures, which are very effective for the treatment ofBPPV. Nevertheless, the recurrence of BPPV may occur after the initial successful treatment. The purpose of this study was to investigate the risk factors and clinical features of recurrentBPPV. Subjects and Method The retrospective study was performed for 227 patients who werediagnosed with BPPV and treated with appropriate canalith repositioning procedures from March2013 to December 2014. We analyzed various clinical characteristics, locations and types of canalithfor the whole BPPV patients, and the interval and frequency of recurrence in the patients ofrecurrent BPPV. Results Of the total of 227 BPPV patients, 47 patients were recurrent BPPV (21%). The patientsof recurrent BPPV were significantly older than those of non-recurrent BPPV (p=0.034). BPPV patients recurred more with increased age, with the significantly increased frequencyof recurrence (p=0.010). Twenty two patients were posterior semicircular canal canalolithiasis(PSCC) (46.8%) and 25 patients were lateral semicircular canal canalolithiasis (LSCC)(53.2%). The number of canalith repositioning procedures was significantly higher in LSCCpatients than in PSCC patients (p=0.041). The location change of affected canal were identifiedfor 23 patients and the type change of LSCC to ipsilateral PSCC was the most common. Conclusion Age is an important prognostic factor to be considered in BPPV recurrence. Also, the affected semicircular canals were frequently changed in the recurrent BPPV.

      • KCI등재

        성향점수매칭을 이용한 돌발성 난청환자에서 초기 고실 내 스테로이드 주입법 및구제치료 요법의 치료 성적 비교

        서희원,이하나,전현웅,변하영,정재호,이승환 대한이비인후과학회 2020 대한이비인후과학회지 두경부외과학 Vol.63 No.6

        Background and Objectives We aimed to compare the treatment outcomes of primary intratympanicsteroid (ITS) and the salvage ITS protocol. Subjects and Method We assessed 440 patients with unilateral idiopathic sudden sensorineuralhearing loss (ISSNHL) from January 2016 to December 2019. Of the 440 patients, 37patients received ITS only as a primary treatment while other patients received systemic steroid;of those remaining patients, 276 received systemic steroid as well as ITS as a salvagetreatment. We performed a 1:2 propensity score matching analysis for both groups using parameterssuch as the initial hearing level, presence of vertigo, onset of treatment, age, sex, hypertensionand diabetes. The rate of hearing recovery was determinied by comparing thematching propensity score between the primary ITS and the control group according to theAmerican Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) guideline andSiegel’s criteria. Results Of the 440 ISSNHL patients, 28.9% received systemic steroid only and 62.6% ofpatients were managed with systemic steroid plus salvage ITS. Thirty-seven patients (8.4%)were managed with ITS only. While 36.8% of patients completely recovered, 35.0% did notrecover their hearing according to AAO-HNS guideline. The propensity score matchingshowed that the initial hearing level, age and onset of treatment were not significantly differentbetween the primary ITS and control group. Regarding the treatment outcome, completerecovery rate for the primary ITS group and control group were 29.7% and 33.8%, respectively. Although the recovery rate of the salvage ITS protocol group was higher than that of theprimary ITS group, statistical significance was not identified. Conclusion Treatment strategies of primary ITS and salvage ITS protocol did not significantlyaffect the clinical outcomes of ISSNHL differently.

      • 후두에 발생한 염증성 근섬유모세포종 1 례

        박상규(Sang Gyu Park),김예슬(Yeseul Kim),전현웅(Jun Hyun Woong),송창면(Chang Myeon Song) 대한두경부종양학회 2019 대한두경부 종양학회지 Vol.35 No.2

        Inflammatory myofibrolastic tumor (IMT) is a rare borderline neoplasm. It frequently occurs in the lung but occasionally occurs in extrapulmonary sites such as the genitourinary tract, gastrointestinal tract, breast, salivary glands, sinonasal tract, orbit, and the central nervous system. Laryngeal involvement of IMT is very rare. A 61-year-old woman who complained of hoarseness persisting for 3 months visited our hospital. Laryngoscopy showed an elevated lesion in the right true vocal cord. Incisional biopsy was confirmed as larygeal inflammatory myofibrolastic tumor. We performed a transoral excision with CO2 LASER under suspension examination. Regional recurrence or distant metastasis was not observed after 9 months of follow-up. Herein we report a case of larygeal inflammatory myofibrolastic tumor that was treated with surgery alone, with a literature review.

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