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박찬범,임병원,박종흥,Park, Chan-Beom,Lim, Byeng-Won,Park, Jong-Heng 한국전자통신연구원 1990 전자통신동향분석 Vol.5 No.4
현재 계측기산업은 빠른 속도의 발전을 거듭하고 있는 전자산업에서의 하나의 핵심분야로 나타나고 있는바, 단일 계측기의 질적 향상에서 탈피하여 컴퓨터와 계측장비를 연결해 계측절차를 간소화 한 CAT(Computer Aided Test)가 등장하고 있으며, 또한 계측기 분야의 신혁명이라고 불리는 표준화된 VXIbus와 MMS 등이 개발되고 있어 이 분야의 새로운 장을 열고 있다. 오실로스코프, 스펙트럼 애널라이저 등 단일 계측장비의 성능 제고가 지난 80년대의 업적이라면 향후 전개될 90년대는 계측시스템 간의 통합화와 표준화라고 볼 수 있다.기술적으로 개방되고, 모듈화 된 계측기 표준에 대한 필요성이 점차로 증가함에 따라 개발된 VXIbus시스템은 모듈기기의 개방구조로서 H/W 및 S/W로 구성되어 있으며, 현재 많이 사용되고 있는 VMEbus를 계측기기에 적합하도록 확장시킨 것이다. 분문에서는 계측시스템의 일반적인 발전추세를 비롯하여 VXIbus의 세부구조, 전기적 기능, 응용 등의 세부내용을 나타내고 있다.
쥐의 국소 허혈 재관류 모델에서 허혈 전후에 투여한 Propofol의 심근 보호 효과
신일우,임병원,정영석,이효민,손주태,이헌근,정영균 대한마취통증의학회 2008 Korean Journal of Anesthesiology Vol.53 No.3
Background: It is known that propofol protects myocardium against a global ischemia-reperfusion injury in the isolated rat heart model. The aim of this study was to investigate whether propofol, at a clinically relevant concentration infused during the peri-ischemic period, also provides a protective effect against a regional myocardial ischemia-reperfusion injury in vivo. Methods: Rats were subjected to 25 minutes of coronary artery occlusion followed by 24 hours of reperfusion. Propofol or intralipid was administrated during 35 minutes starting 5 minutes before the onset of ischemia until 5 minutes after the onset of reperfusion. A micromanometer catheter was advanced into the left ventricle and the hemodynamic function was evaluated. The infarct size was determined by triphenyltetrazolium staining after 24 hours of reperfusion. Results: Propofol administration during the peri-ischemic period demonstrated protective effects on hemodynamic function and infarct size reduction. In the control group, the peak rate of the ventricular pressure increase (+dP/dtmax)(P = 0.0001) and the peak rate of the intraventricular pressure decline (−dP/dtmax)(P = 0.0001) were significantly decreased compared to the sham group. In the propofol group, the +dP/dtmax (P = 0.003) and −dP/dtmax (P = 0.002) were significantly improved compared to the control group. The infarct size was 47.6% of the area at risks in the control group, and was reduced markedly by administration of propofol during the peri-ischemic period to 26.2% in the propofol group (P = 0.004). Conclusions: Propofol, at a clinically relevant concentration infused during the peri-ischemic period, have protective effect after regional myocardial ischemia-reperfusion injury in an in vivo rat heart model Background: It is known that propofol protects myocardium against a global ischemia-reperfusion injury in the isolated rat heart model. The aim of this study was to investigate whether propofol, at a clinically relevant concentration infused during the peri-ischemic period, also provides a protective effect against a regional myocardial ischemia-reperfusion injury in vivo. Methods: Rats were subjected to 25 minutes of coronary artery occlusion followed by 24 hours of reperfusion. Propofol or intralipid was administrated during 35 minutes starting 5 minutes before the onset of ischemia until 5 minutes after the onset of reperfusion. A micromanometer catheter was advanced into the left ventricle and the hemodynamic function was evaluated. The infarct size was determined by triphenyltetrazolium staining after 24 hours of reperfusion. Results: Propofol administration during the peri-ischemic period demonstrated protective effects on hemodynamic function and infarct size reduction. In the control group, the peak rate of the ventricular pressure increase (+dP/dtmax)(P = 0.0001) and the peak rate of the intraventricular pressure decline (−dP/dtmax)(P = 0.0001) were significantly decreased compared to the sham group. In the propofol group, the +dP/dtmax (P = 0.003) and −dP/dtmax (P = 0.002) were significantly improved compared to the control group. The infarct size was 47.6% of the area at risks in the control group, and was reduced markedly by administration of propofol during the peri-ischemic period to 26.2% in the propofol group (P = 0.004). Conclusions: Propofol, at a clinically relevant concentration infused during the peri-ischemic period, have protective effect after regional myocardial ischemia-reperfusion injury in an in vivo rat heart model
전동석,임병원,박찬범,Jun, D.S.,Lim, B.W.,Park, C.B. 한국전자통신연구원 1993 전자통신동향분석 Vol.8 No.2
발진기의 특정시간 동안의 주파수 안정도 측정을 위하여 시간영역에서의 측정방법인 알랜분산(Allan Variance)을 응용하였으며, 기준 주파수는 GPS 위성으로부터 세계시를 수신하여 이용하였다. 또한 측정시스팀의 자동제어 및 측정 데이터의 처리를 위한 S/W를 개발하여 GPS를 이용한 주파수 안정도 측정시스팀을 개발하였다.