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Paraquat 중독환자에 대한 Hemoperfusion 의 치료효과
이태헌(Tae Hun Lee),양성욱(Seong Wook Yang),이태관(Tae Kwan Lee),최수영(Su Young Choi),이용응(Yong Ung Lee),이광영(Kwang Young Lee) 대한내과학회 1997 대한내과학회지 Vol.52 No.1
N/A Paraquat is a very potent herbicide which causes fatal toxicity when ingested, and there is no specific antidote against it. So it is known that most of the patients who ingested it die of pulmonary fibrosis. We used hemoperfusion(HP) for the treatment against paraquat poisoning from July 1993 till March 1994 and analysed the data using SPSS/PC ver4.0 for chi-square and t-test for mean±SD. The results were as follows: 1) A total of 36 paraquat poisoning patients(22 males and 14 females, mean age 48.8 years) visited our hospital, and i8 patients out of 36 received hemoperfusion(total 90 cycles); there were statistically significant differences in ages(41.4±15.6 year vs 56.2±15.0 year, p<0.05), but there was no significant difference in the amount of paraquat ingested(59.6±72.7ml vs 78.6±83.6ml, p=NS), gastric lavages(13/18 vs 16/18, p=NS), and use of Fuller's earth(8/18 vs 4/18, p=NS) between the patients who received HP and those who did not receive HP. 2) All the patients who did not receive HP died, but 9 patients out of 18 who received HP survived(p<0.005). There was no significant difference in ages(46.8±9.8 year vs 36.0±18.8 year, p=NS), amount of paraquat ingested(87.5±94.2 ml vs 34.8±36.4 ml, p=NS), gastric lavages(7/9 vs 6/9, p=NS), use of Fuller`s earth(5/9 vs 3/9, p=NS), and interval from the ingestion of paraquat to HP(52.449.9 hr vs 38339.7 hr, p=NS) between patients who died and those who survived, but SCr levels on arrival in expired patients were higher than those in surviving patients(5.0±3.5mg/dl vs 1.4±0.6mg/dl, p<0.05). Therefore, this suggests that hemoperfusion is very effective in the treatment of paraquat poisoning, and hemoperfusion is the most important factor in the prognosis of the patients.
여과분리형 생물반응조를 이용한 디메틸포름아미드 제거 특성
정용준 ( Yong Jun Jung ),이태관 ( Tae Kwan Lee ) 한국수처리학회 2010 한국수처리학회지 Vol.18 No.6
The removal properties of dimethylformamide were examined with filtration bio-reactor equipped with filter media. The formation of sludge cake layers to get enough good quality of the effluent by filtration was obtained within 2 minutes after aeration cleaning, where the filtrate showed over 80 NTU at the initial period and below 10 NTU at the stable filtration period. The filtration time over 2,500 ㎎/L of DMF concentration was shown more than 80 minutes, but it showed less than 60 minutes below 1,000 ㎎/L of DMF concentration. The removal efficiency of TOC was over 90% when the concentration of the influent was increased. SS and Colority of the filtrate were shown the similar removal pattern with the filtration time. Therefore, this system may be expected to the treatment of dimethylformamide wastewater.
증예(症例) : 비특이적 증상을 나타낸 각 유전분증 1예
김용석 ( Yong Seok Kim ),조진웅 ( Jin Woong Cho ),최순필 ( Soon Pil Choi ),이진구 ( Jin Gu Lee ),김양호 ( Yang Ho Kim ),임지현 ( Ji Hyun Lim ),이태관 ( Tae Kwan Lee ),이용웅 ( Yong Woong Lee ) 전북대학교 의과학연구소 2002 全北醫大論文集 Vol.26 No.1
유전분증에 대해서는 많은 보고들이 있으나 간 유전분증의 경우는 비교적 드물게 보고되고 있으며 특히 초기에 간종대와 간기능검사상 이상소견 외에 다른 증상이 없는 유전분증의 경우는 매우 드물다. 따라서 저자들은 비특이적 증상을 주소로 내원하여 이학적 검사상 간비대와 간기능 검사상 이상소견을 보인 간 유전분증 환자를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Amyloidosis results from the deposition of insoluble, fibrous amyloid protein, mainly in the extracellular spaces of organs and tissues. Depending upon the biochemical nature of the fibril protein and the area of the body that is involved, the clinical manifestations of amyloidosis are varied. Hepatic manifestation consists of hepatomegaly, liver function abnormalities, portal hypertension, ascites, intrahepatic cholestasis. but, initial symptoms are minimal. We report the case of hepatic amyloidosis which was characterized by hepatomegaly and liver function test abnormalities, but another symtptoms was not typical.