국제공유하천으로서의 메콩강에 관한 법적 고찰 - 메콩협약과 UNWC의 비교를 중심으로 -

이준표 ( Lee Joon Pyo ) 한국외국어대학교 동남아연구소 2017 東南亞硏究 Vol.26 No.3

International water laws define the legal rules for international water sharing among two or more countries. Currently, over 3,600 bilateral or multilateral international agreements have been signed all over the world. Although such international water agreements significantly reduce the possibility of conflict occurring, none of them is perfect and able to resolve all conflicts. In 1997, more than one hundred nations joined together to adopt the United nations Convention on the Law of the non-navigational uses of International Watercourses(UNWC)―a flexible and overarching global legal framework that establishes basic standards and rules for cooperation between watercourse states on the use, management, and protection of international watercourses. UNWC entered into force on August 2014 when Viet Nam became the required 35th country to ratify the UNWC. In the Mekong region, one such basin-specific treaty is the Mekong Agreement. Entering into force in 1995, the Mekong Agreement was adopted by the Lower Mekong Basin states of Cambodia, Lao PDR, Thailand and Viet Nam, and was accompanied by the establishment of a robust inter- governmental basin institution, the Mekong River Commission (MRC). Yet, 20 years later, the ability of the Mekong Agreement and MRC to effectively govern trans-boundary watercourse management in the region have been called into question, in particular regarding disputes related to the rapid development of hydropower dams along the river and its tributaries. The entry into force of the UNWC presents an opportunity to seek a common approach for strengthening trans-boundary water governance in the Mekong Basin. By its very nature, this framework convention provides a central body of international law on which to build basin-wide uniformity for the MRC and its member States. This will provide basin-wide consistency in the effective governance and regulation of riparian state practices. This paper provides a comparative analysis of the key substantive and procedural principles and obligations provided for in the two treaties.

호랑나비 유래 항균 펩타이드 파필리오신 3의 항염증 활성

신용표(Yong Pyo Shin),이준하(Joon Ha Lee),김인우(In-Woo Kim),서민철(Minchul Seo),김미애(Mi-Ae Kim),이화정(Hwa Jeong Lee),백민희(Minhee Baek),김성현(Seong Hyun Kim),황재삼(Jae Sam Hwang) 한국생명과학회 2020 생명과학회지 Vol.30 No.10

본 연구에서는 호랑나비 유충의 유전체 분석을 통해 선별된 파필리오신 3의 항균 및 항염증 활성을 확인하였다. 선행연구에서 RNA 시퀀싱 분석을 통해 호랑나비의 전사체를 분석하였으며, 결과를 바탕으로 인실리코(in silico)분석을 진행하여 전사체 유래 항균 펩타이드를 스크리닝하고 선발하였다. 수행된 항균 활성 및 용혈 활성 테스트에서 파필리오신 3은 그람음성균인 E. coli와 그람양성균인 S. aureus에 대해 강력한 항균활성을 나타낸 반면 마우스 적혈구에 대한 용혈 활성은 전혀 없었다. 다음으로 마우스 대식세포주 Raw264.7 세포를 이용하여 파필리오신 3의 항염증 활성을 확인하였다. 그 결과 파필리오신 3은 LPS로부터 유도된 Raw264.7 세포들의 산화질소 생성을 감소시키는 결과를 보여주었다. 뿐만 아니라 실시간 역전사 중합효소 연쇄반응(qRT-PCR) 방법과 효소결합 면역흡착측정법(ELISA)을 통해 파필리오신 3이 Raw264.7 세포에서 전염증성 사이토카인(IL-6, IL-1β)의 발현을 감소시킨다는 것을 확인할 수 있었다. 또한, 염증반응의 신호전달인자들(MAPKs, NF-κB)의 인산화를 억제하는것을 확인하였는데, 이는 파필리오신 3이 LPS와의 상호작용을 통해 결합하여 효과를 나타낸다는 것을 확인할 수 있었다. 이러한 결과들은 호랑나비 유전체 분석을 통해 확인된 파필리오신 3이 새로운 항균 및 항염증 치료제로서 개발하는데 가능성 있는 물질로 사료된다. The development of novel peptide antibiotics with potent antimicrobial activity and anti-inflammatory activity is urgently needed. In a previous work, we performed an in-silico analysis of the Papilio xuthus transcriptome to identify putative antimicrobial peptides and identified several candidates. In this study, we investigated the antibacterial and anti-inflammatory activities of papiliocin 3, which was selected bioinformatically based on its physicochemical properties against bacteria and mouse macrophage Raw264.7 cells. Papiliocin 3 showed antibacterial activities against E. coli and S. aureus without inducing hemolysis and decreased the nitric oxide production of the lipopolysaccharide-induced Raw264.7 cells. Moreover, ELISA and Western blot analysis revealed that papiliocin 3 reduced the expression levels of pro-inflammatory enzymes, such as inducible nitric oxide synthase (iNOS), cyclooxygenase- 2 (COX-2), and prostaglandin E2 (PGE2). In addition, we examined whether papiliocin 3 could inhibit the expression of pro-inflammatory cytokines (interleukin-6 and interleukin-1β) in LPSinduced Raw264.7 cells. We found that papiliocin 3 markedly reduced the expression level of cytokines through the regulation of mitogen-activated protein kinases (MAPK) and nuclear factor kappa B (NF-κB) signaling. We also confirmed that papiliocin 3 binds to bacterial cell membranes via a specific interaction with lipopolysaccharides. Collectively, these findings suggest that papiliocin 3 could be a promising molecule for development as a novel peptide antibiotic.

IEEE 802.1x 프레임워크 기반에서의 무선랜 보안 강화 방안에 관한 연구

이준,홍성표,신명숙,Lee Joon,Hong Seong-pyo,Shin Myeong-sook 한국정보통신학회 2006 한국정보통신학회논문지 Vol.10 No.1

IEEE 802.1x는 EAP(Extended Authentication Protocol)를 통해 해쉬 함수를 이용한 Challenge/Response, Keberos, 인증서를 기반으로 하는 TLS, One-Time Password 등 다양한 사용자인증 메커니즘들을 지원한다. 그러나 AP에 대한 인증 및 암호 메커니즘의 부재와 인증 프로토콜의 구조적 원인에 의해 스푸핑 및 DoS(Denial of Service) 공격 등에 취약하다. 본 논문에서는 IEEE 802.1x 프레임워크의 스푸핑 및 DoS 공격 취약성을 보완하여 안전한 사용자 인증 및 암호통신 서비스를 제공하는 무선랜 보안시스템을 제안하고자 한다. 제안 시스템은 공개키 암호기술을 이용하여 전송 메시지에 대한 무결성 서비스를 통해 안전한 암호통신을 제공하며, 인증초기단계를 통해 DoS 공격을 방지한다. The IEEE 802.1x can be using various user authentication mechanisms: One-Time Password, Certificate-Based TLS, Challenge/Response and Keberos through EAP(Extended Authentication Protocol). But, IEEE 802.1x also has vulnerabilities about the DoS, the session hijacking and the Man in the Middle attack due to the absence of AP authentication. In this paper, we propose a WLAN secure system which can offer a safety secure communication and a user authentications by intensified the vulnerability of spoofing and DoS attacks. The suppose system offers a safe secure communication because it offers sending message of integrity service and also it prevents DoS attack at authentication initial phase.

동남아시아 체제전환국가의 법체계 및 기업입법 동향

이준표 ( Lee Joon-pyo ) 한국외국어대학교 법학연구소 2012 외법논집 Vol.36 No.3

Vietnam, Cambodia, Laos and Myanmar are the so-called transition countries in the Southeast Asia. In the late 1980s, Vietnam, Cambodia, Laos and Myanmar abandoned their centrally-planned, socialist models and began the transition to more open and market-oriented capitalist economies. This paper introduces the legal systems of the so-called transition countries and examines each country’s Enterprise law with respect to legislative background, structure and characteristics. These countries have continuously legislated and revised Enterprise Law toward a progressive direction. But it is still uncertain to make sure the effectiveness of Enterprise Law because of each country’s political and social issues. In fact, there are not much of lawsuits or precedents which are based on their enterprise Law. Therefore, the most important task for Enterprise Law of these countries is to increase the effectiveness of Enterprise Law and help these countries establish and manage forms. As I mention earlier, regulations of Korea Enterprise Law could be good examples to modify Enterprise Law of these countries.

메콩경제권 국가들의 기업법상 회사설립제도 -한국 상법과의 비교를 중심으로-

이준표 ( Joon Pyo Lee ) 한국외국어대학교 동남아연구소 2012 東南亞硏究 Vol.22 No.1

The Greater Mekong Subregion(GMS) is a development project set by the Asian Development Bank in 1992. GMS`s countries consist of six countries near the Mekong River basin, namely Cambodia, Laos, Myanmar, Thailand, Vietnam and the Yunnan Province of China. With assistance from the Asian Development Bank, the six countries entered into a program of subregional economic cooperation, designed to enhance economic relations among the countries. In particularly China, Vietnam, Cambodia, Laos and Myanmar are the so-called transition countries. In the late 1980s, China, Vietnam, Cambodia, Laos and Myanmar abandoned their centrally-planned, socialist models and began the transition to more open and market-oriented capitalist economies. This paper introduces the framework of the Enterprise Law comparing with the Korean law in some points. Especially, this paper focuses on the company`s establishment. Vietnam and Thailand have recently revised the Enterprise law. It significantly improved the process for forming a new company. The Enterprise Law creates more transparent procedures for private businesses, significantly simplifies regulations and procedures to start businesses, and moves from discretionary licensing to automatic registration, by way of the implementation of a negative list of restricted or prohibited activities. However, the ambiguity in licensing and regulatory procedures impedes the daily work and growth opportunities of enterprises. Furthermore, the continued state domination of the national economy limits the opportunities for robust private enterprise. Therefore, more comparative studies on the enterprise law of advanced industrial nations including Korea can be essential for the development of enterprise law in GMS`s countries.

사우디 회사법상 회사설립 규정의 비교법적 고찰

이준표 ( Lee Joon-pyo ),왕석동 ( Wang Seok-dong ) 한국외국어대학교 법학연구소 2013 외법논집 Vol.37 No.4

The Saudi Arabian economy has dramatically been changed with the development of oil industry and industrialization. With the discovery of massive oil resource, huge amounts of oil money have composed of big part in the Saudi Arabian economy. Moreover, Saudi Arabia became the wealthiest nation of the Middle Eastern countries. As getting advantage of the oil money, the Saudi Arabian government, since the 1970, has pursued industrial development. Development of the national economy was based on government’s plan, which the government needed more advanced foreign technology and foreign investment. For this reason, the government made a policy that help the foreigners to invest the Saudi Arabian industries. Also, many foreigners want to expand their entities in Saudi Arabian market. As wishing to conduct business in Saudi Arabia, Foreigners can establish their own company in Saudi Arabia. The general law with regard to formation and governance of companies in Saudi Arabia is the Company Law enacted by Royal Decree No.6, 1965. Under the Saudi Arabian Companies Law, the definition of company is a contract pursuant to which each of two or more persons undertake to participate, in an enterprise aiming at profit, by offering in specie or as work a share, for sharing in the profits or losses resulting from such enterprise. In addition, companies can select any type of forms that are General Partnerships, Limited partnerships, Joint Ventures, Corporations, Partnerships Limited by Shares, Limited Liability Partnerships, Variable Capital Companies, Cooperative Companies. Each company has distinguishing establishment procedure rules in campany law. Although many of Korean companies enter into the Saudi Arabian market, there are few studies which provide the establishment procedure of the Saudi Arabian Company Law. In particular, the amount of trade between Saudi Arabia and Korea has increased sharply with FTA. Thus it is important to study the Saudi Arabian Company Law.

아메리카왕거저리 유래 항균 펩타이드 조포바신 1의 항염증활성

신용표(Yong Pyo Shin),이준하(Joon Ha Lee),김인우(In-Woo Kim),서민철(Minchul Seo),김미애(Mi-Ae Kim),이화정(Hwa Jeong Lee),백민희(Minhee Baek),김성현(Seong Hyun Kim),황재삼(Jae Sam Hwang) 한국생명과학회 2020 생명과학회지 Vol.30 No.9

본 연구에서는 아메리카왕거저리에 대한 기능성 연구의 일환으로 아메리카왕거저리 유충의 유전체 분석을 통해 선별된 조포바신 1의 항균 및 항염증 활성을 확인하였다. 선행연구에서 RNA 시퀀싱을 통해 아메리카왕거저리의 전사체를 분석하였으며, 결과를 바탕으로 인실리코(in silico) 분석을 수행하여 전사체 유래 항균 펩타이드를 스크리닝하고 선발하였다. 수행된 항균활성 및 용혈활성 테스트에서 조포바신 1은 세균 및 칸디다 진균에 대해 광범위한 항균활성을 나타낸 반면 마우스 적혈구에 대한 용혈활성은 전혀 없었다. 다음으로 마우스 대식세포주 Raw264.7 세포를 이용하여 조포바신 1의 항염증활성을 확인하였다. 그 결과 조포바신 1은 LPS로부터 유도된 Raw264.7 세포들의 산화질소 생성을 감소시키는 결과를 보여주었다. 뿐만 아니라 실시간 역전사 중합효소 연쇄반응(qRT-PCR) 방법과 효소결합면역흡착측정법(ELISA)을 통해 조포바신 1이 Raw264.7 세포에서 전염증성 사이토카인(IL-6, IL-1β)의 발현을 감소시킨다는 것을 확인할 수 있었다. 또한 염증반응의 신호전달인자들(MAPKs, NF-κB)의 인산화를 억제하는 것을 확인하였다. 게다가 조포바신 1은 LPS와의 상호작용을 통해 결합한다는 것을 확인하였다. 이러한 연구결과들은 아메리카왕거저리 유전체 분석을 통해 확인된 조포바신 1이 항균 및 항염증 치료를 위한 물질로서 개발하는데 가능성이 있을 것으로 사료된다. The giant mealworm beetle, Zophobas atratus (Coleoptera: Tenebrionidae) has been used as a protein source for small pets and mammals. Recently, it was temporarily registered in the list of the Food Code. We previously performed an in silico analysis of the Zophobas atratus transcriptome to identify putative antimicrobial peptides and identified several antimicrobial peptide candidates. Among them, we assessed the antimicrobial and anti-inflammatory activities of zophobacin 1 that was selected bioinformatically based on its physicochemical properties against microorganisms and mouse macrophage Raw264.7 cells. Zophobacin 1 showed antimicrobial activities against microorganisms without inducing hemolysis and decreased the nitric oxide production of the lipopolysaccharide-induced Raw264.7 cells. Moreover, ELISA and Western blot analysis revealed that zophobacin 1 reduced expression levels of pro-inflammatory enzymes such as inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). We also investigated expression of pro-inflammatory cytokines (interleukin-6 and interleukin-1β) production through quantitative real time-PCR and ELISA. Zophobacin 1 markedly reduced the expression level of cytokines through the regulation of mitogen-activated protein kinases (MAPKs) and nuclear factor kappa B (NF-κB) signaling. We confirmed that zophobacin 1 bound to bacterial cell membranes via a specific interaction with lipopolysaccharides. These data suggest that zophobacin 1 could be promising molecules for development as antimicrobial and anti-inflammatory therapeutic agents.

메콩경제권 국가들의 기업법에 관한 비교법적 고찰 -회사의 설립을 중심으로-

이준표 ( Joon Pyo Lee ) 연세대학교 법학연구원 글로벌비즈니스와 법센터 2012 연세 글로벌 비즈니스 법학연구 Vol.4 No.1

The Greater Mekong Subregion(GMS) is a development project set by the Asian Development Bank in 1992. GMS`s countries consist of six countries near the Mekon g River basin, namely Cambodia, Laos, Myanmar, Thailand, Vietnam and the Yunnan Province of China. With assistance from the Asian Development Bank, the six countr ies entered into a program of subregional economic cooperation, designed to enhanc e economic relations among the countries. In particularly China, Vietnam, Cambodia, Laos and Myanmar are the so-called transition countries. In the late 1980s, China, Vietnam, Cambodia, Laos and Myanmar abandoned their centrally-planned, socialist models and began the transition to more open and market-oriented capitalist econom ies. China, Vietnam and Thailand have recently revised the Enterprise law. It significan tly improved the process for forming a new company. The Enterprise Law creates more transparent procedures for private businesses, significantly simplifies regulation s and procedures to start businesses, and moves from discretionary licensing to auto matic registration, by way of the implementation of a negative list of restricted or prohibited activities. However, the ambiguity in licensing and regulatory procedures impedes the daily work and growth opportunities of enterprises. Furthermore, the continued state domination of the national economy limits the opportunities for robu st private enterprise. Therefore, more comparative studies on the enterprise law of advanced industrial nations including Korea can be essential for the development of enterprise law in GMS`s countries.

베트남 프랜차이즈 관련 규제의 형성과 발전

이준표(Lee, Joon-Pyo) 동아대학교 법학연구소 2020 東亞法學 Vol.- No.88

본 연구는 베트남의 프랜차이즈 법제정비동향과 현행 베트남 프랜차이즈 규제의 주요 내용을 고찰하는 것을 목적으로 한다. 베트남에는 한국과 달리 프랜차이즈 거래만을 규율하는 프랜차이즈 관련 통합법이 존재하지 않는다. 그러나 상법을 중심으로 한 기본법 체계가 잘 갖추어져 있다. 또한 시행령이나 시행규칙 등을 지속적으로 제․개정하고 있을 뿐 아니라, 내용에 있어서도 프랜차이즈 활동의 규제를 완화하고 철폐하는 등 프랜차이즈 산업 발전을 위한 노력을 지속하고 있다. 상법상 구체적인 프랜차이즈 규제 내용과 관련하여, 최근 주목할 만한 개정사항이 발표되었다. 프랜차이즈 관련 행정절차를 줄이고 업무를 용이하게 하는데 목적이 있는 것으로 평가된다. 다만, 프랜차이즈의 등록 의무는 그대로 존속하고 있으며, 주무부서인 산업무역부가 가맹업자에 대하여는 관련 법령을 엄격하게 해석하고 있다. 한편, 베트남은 여전히 정치적으로는 사회주의를 택하고 있기 때문에, 베트남 특유의 법치에 대한 이해 없이, 단순한 법규의 분석만으로 베트남 법제도를 이해하는데 한계가 있다. 또한 도이머이 개혁이후, 법체계가 확립되어 가는 과정 속에서 분쟁의 감소, 예측가능성의 증가 등의 긍정적인 변화를 부인할 수 없지만, 사법독립과 법적 이행력의 한계는 여전하다. 베트남이 기대하는 프랜차이즈 산업의 지속적으로 발전을 위하여, 먼저 투명하고 정확한 법제도적 기반이 마련되어야 할 것이다. The purpose of this study is to examine the trend of Vietnam"s franchise legislation and the main contents of the current Vietnam franchise regulation. In Vietnam, unlike Korea, there is no franchise-related consolidation law. However, the basic law system centered on commercial law is well established. In addition, it not only continuously enacts and revises the enforcement ordinances or enforcement regulations, but also continues to make efforts to develop the franchise industry by easing and eliminating regulations on franchise activities. On the other hand, since Vietnam still chooses to remain a socialistic country, there is a limit to understand the Vietnamese legal system by simply analyzing laws and regulations without understanding Vietnam"s unique laws. In addition, after the reform of Doi-Moi, it is undeniable that positive changes, such as decrease in dispute and increase of predictability, can occur in the process of establishing a legal system, but the limits of judicial independence and legal performance remain unsolved. For the continued development of the franchise industry that Vietnam expects, a transparent and accurate legal and institutional foundation must be established beforehand.

음식폐기물의 혐기성 분해에 대한 암모니아와 염분의 영향

이준표(Joon Pyo Lee),박순철(Soon Chul Park),이승희(Seung Whee Rhee) 大韓環境工學會 1997 대한환경공학회지 Vol.19 No.9