http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
이재호(JH Lee),이석(S Lee),김택훈(TH Kim),서영욱(YU Suh) 대한산부인과학회 1986 Obstetrics & Gynecology Science Vol.29 No.6
선천성 강결손 및 조강술 Six cases of congenital absence of vagina have been reviewd. Congenital absence of vaginal is a rare malformation usually associated with Mullerian duct abnormalities. McIndoe procedure has been performed world-widely because of it`s simplicity, low mortality and high degree of physiologic sucess. Authors analized clinically 6cases of congenital absence of vagina patients who received McIndoe procedure during the period form 1974 to 1985.
질에 원발한 Endodermal Sinus Tumor 의 1 예
이재호(JH Lee),임희재(HJ Lim),장윤석(YS Chang) 대한산부인과학회 1978 Obstetrics & Gynecology Science Vol.21 No.8
Endodermal sinus tumors are rare and highly malignant germ cell tumors in both gonadal and extragonadal tissues. Primary vaginal endodermal sinus tomors(such as present case) are predominatly tumors of infants, and carry a dismal prognosis. The recent occurrence of such a neoplasm, in an 18-month-old child treated postoperatively with multiple courses of combined chemotherapy followed by apparent improvement in the level of alpha-fetoprotein, prompted us to review the lassical and current world literature on these tuumors. This appears to be the first case reported in Korea.
태아 및 성인에서의 자궁경부조직 및 혈장 Carcinoembryonic Antigen의 동태에 관한 연구
이재호(JH Lee) 대한산부인과학회 1985 Obstetrics & Gynecology Science Vol.28 No.1
Since its original description in patients with colonic adenocarcinoma by Gold and Freedman, carcinoembryonic antigen(CEA) has been isolated in the plasma and tumors of patients with variety of neoplasms. In gynecologic cancer, CEA has been elevated most frequently in the plasma of patients with ovarian and cervical carcinomas. CEA can also be detected during oncogenesis. Gold and Freedman investigated several embryonic and fetal tissue extracts for the presence of this oncofetal antigen in their precipitin-inhibition assays. But their study did not make use of a specific anti-CEA antiserum since the non-specific cross-reacting antigen(NCA) had not yet been defined. And it should be noticed that in healthy adult, an antigen that shares antigenic determinants with CEA-nonspecific cross-reacting antigen (NCA)-can be found in blood and several tissues, including the colon, lung, and spleen. Some of the physical properties of CEA are as follows: (1) molecular weight 200,000; (2) glycoprotein; (3) sedimentation constant of 7~8 S; (4) 50~60% carbohydrate (sialic acid, mannose, galactose, acetyl-N-glucosamine, and fucose), (5) polypeptide 40%. But the biologic function of CEA is not clarified. Although colonic cancer CEA and cervical CEA may have different molecular sizes, they share antigenic determinants which are indistinguishable in gell diffusion method. The relationship between embryonic development and neoplasia has been a central theme of cancer research for a decade. The apparent activation of silent genes normally only expressed in the embryo may provide a most valuable lead for basic cancer research concerned with the nature of the malignant transformation. So knowledge of the normal CEA distribution in fetal cervix should be of interest in studying and understanding the behavioural characteristics of CEA and its significance in carcinogenesis of cervical carcinoma. Therefore, 16 fetal cervices, 37 normal adult cervices, 18 cervical dysplasias, and 113 cervical carcinomas were stained by immunoperoxidase method to determine the presence, distribution, and significance of CEA. And serum CEA levels were also determined concomitantly to evaluate the plasma CEA patterns and the correlation between the tissue CEA levels and plasma CEA levels in the patients with cervical carcinoma.
소프트스위칭 ZVZCS를 이용한 고속전철 보조전원장치 Battery Charger 개발
최욱돈(UK Choi),이종찬(JC Lee),이재문(JM Lee),이재호(JH Lee),최항석(HS Choi) 전력전자학회 1999 전력전자학술대회 논문집 Vol.1999 No.7
고속전철의 보조 전원 장치는 차량에 탑재되므로 소형화, 경량화 및 고신뢰성이 요구된다. 보조전원 장치중 Battery Charger는 고압의 직류전원 (670Vdc)을 저압의 직류전원 (83Vdc)으로 변환하여 객차 (Trailer Car: 50kW) 및 동력차(Power Car: lOkW)에 필요한 직류천원을 안정되게 공급하고 Battery Charger의 고장 발생 시를 대비해 Battery의 최적 충전상태를 유지해야 한다. 기술개발의 최종 목표는 고효율, 고신뢰성 밧데리 충전기 시스템 개발. EMI 저감, 부피와 무게의 소형경량화, 최적 스위칭 기술 및 회로 개발이다. IGBT 에 대해 소프트 스위칭 기법을 사용 하여 스위칭 손실 저강 및 소자의 스트레스의 저감으 로 전력 변환 장치의 효율 향상과 소자의 신뢰성을 확보하였고, 스위칭 주파수를 높여 변압기나 인덕터등의 자기 소자의 크기를 줄였다. Battery Charger를 단일 모듈로 구성하기 보다 5kW 모듈을 여러개 조합한 다중모듈방법으로 병렬 운전하므로써 입출력 전 류리플룰 감소시켰으며 시스템의 안정성과 신뢰성을 높일 수 있었다.
정자수정능력검사와 일반적인 체외수정과 정자직접주입법에서의 수정률과의 상관관계에 관한 연구
이재호,곽인평,윤태기,차광열,김현규,엄기붕,하정희 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.3
본 연구는 정자의 기능검사와 체외수정[IVF]과 정자직접주입법[ICSI]의 수정률이 상관관계가 있는지를 알아보고자 실시하였다. 3가지의 다른 정자기능검사, 즉 morphology test, hypoosmotic swelling test[HOS], acridine orange[AO] test를 동일한 정액을 대상으로 실시하여 수치화 하였고, IVF와 ICSI를 실시한 후에 이 수치와 수정률과의 관계를 통계검정하였다. Morphology test 결과 정상정자 0∼4%와 5∼14% 범위의 IVF 결과는 각각 5.6%와 43.0%였고, ICSI의 경우는 각각 64.3%와 70.0%였다. IVF의 경우는, 정자의 형태에 따라 수정률이 많은 영향을 받는 것으로 판명되었으나 ICSI를 적용하면 정자 형태에 관계없이 높은 수정률을 얻을 수 있었다. HOS test를 실시한 결과로는 HOS 수치가 60 미만과 이상으로 구분할 때, 수정률은 각각 31.5%와 28.0%로서 낮았다. 동일한 HOS 수치에서 ICSI를 실시한 결과로는 각각 64.7%와 68.4%로서 ICSI를 실시했을 ㄸ의 수정률이 높았다. AO test 결과로는 60 미만과 이상으로 구분할 때, IVF는 23.1%와 29.9%의 낮은 수정률을 보인 반면에 ICSI를 실시했을 때는 69.9%와 67.4%의 높은 수정률을 얻을 수 있었다. 상기의 결과를 종합하면, 정자 형태와 HOS, AO의 검사수치는 상관관계 가 없었고, 정자형태와 IVF에서의 수정률은 상당히 높은 관련성을 보였으며, ICSI를 실시하면, 정자의 성상에 관계없이 높은 수정률을 얻을 수 있다고 사료된다. We compared the results of three different sperm function test ie., sperm morphology test, hypoosmotic test, acridine orange test and the fertilization rates of IVF and ICSI to evaluate whether the sperm tests correlate with the fertilization rates of IVF and ICSI. In normal sperm morphology 0∼4%, the fertilization rates of IVF and ICSI were 5.6%[3/54] and 64.3% [27/42], respectively. In normal sperm morphology 5∼14%, the fertilization rates of IVF and ICSI were 43.0%[40/93] and 70.0%[49/70], respectively. There was a significant difference in the IVF fertilization rates in normal morphology 0∼4% and 5∼14% groups, however no difference was found in the ICSI fertilization rates according to the morphology. In HOS test, the IVF fertilization rates in low and high HOS value were 31.5% and 28.0%, respectively, and no difference was found in the fertilization rates when ICSI was employed according to the HOS value. However, if we compare the IVF and ICSI fertilization rates, significant differences were found. In high[≥ 60%] and low[<60%] AO value groups, the IVF fertilization rates were generally low[23.1 and 29.9, respectively], but higher fertilization rates were achieved in ICSI groups[69.9 and 67.4%, respectively]. No difference was found in the fertilization rates of IVF and ICSI according to AO value, but significant differences were found if we compare the IVF and ICSI fertilization rates. Our results showed that only sperm morphology scoring could predict the IVF fertilization rate, and no sperm characteristics could affect the ICSI fertilization rate.
ICSI를 실시한 2146예 중 수정란이식에 실패한 경우에 대한 원인 분석
이재호,윤태기,차광열,김현주,엄기붕,손지온 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.3
Since the introduction of intracytoplasmic sperm injection [ICSI] by Palermo et al.[1992], ICSI has been widely accepted in many IVF programs, including our own. Since our first successful pregnancy in 1993 using ICSI, we have continued to utilize the method in our IVF program to treat male factor patients. From January 1994 to December 1996, 2146 ICSI cycles were performed, most of the cases involving patients with severe male-factor infertility. The overall fertilization rate from the 2146 cycles was 76.0%. Embryo transfers failed in only 93 cycles[4.3%]. Details of the 93 failed ET`s were analysed. The fertilization rate of the ET failure group was 15.4% and the rates of 1PN and 3PN formation were 1.3% and 5.9%, respectively. A significant difference was found in the 3PN formation rate of the successful ET cycles [1.1%] compared with the 3PN rate of the failed embryo transfer group. The fertilization rate of small number[≤3] of oocyte group was slightly lower than the groups of oocyte number 4∼7 and more than 8. Forty eight cycles out of 93[51.6%] were categorized as having a poor quality oocyte with severe granulation, degenerative signs or abnormal morphology. In 24 cycles where non-motile sperm were used, fertilization did not occur. The women`s ages were not correlated with the fertilization rates. In conclusion, ET failures following ICSI for the treatment of severe male factor infertility was mainly caused by poor quality oocytes and/or poor viability of the spermatozoa used for injection into oocytes.