예정일 초과분만에 대한 임상적 연구

곽인평,윤태기,안동원 대한산부인과학회 1984 Obstetrics & Gynecology Science Vol.27 No.10

골반자궁내막증에 동반된 양성유두상 중피종

곽인평,안희정,이혜경,성혜리,차광열 대한산부인과학회 1995 대한산부인과학회 학술대회 Vol.76 No.-

한 농촌지역 부인들의 대하증에 관한 임상의학적 고찰

곽인평(IP Kwak),곽현모(HM Kwak) 대한산부인과학회 1985 Obstetrics & Gynecology Science Vol.28 No.6

During the 6 months from January 1984 to June 1984, a clinical study on the vaginal discharges in women living in rural area was performed in 692 cases of the gynecological patients in outpatient clinic at Kang Wha Hospital. The results were as follows: 1. The causes of the vaginal discharges in 545 cases were, nonspecific vaginitis 36.5%, candida 23.5%, cervicitis 17.6%, trichomonas 9.2%, excessive but otherwise normal secretions 7.9%, and atrophic vaginitis 4.0%. 2. The prevalences of the vaginal discharges in different age groups were 74.8% in under 24, 74.5% in 25~34, 84.2% in 35~44, 90.0% in above 45. The prevalences of the nonspecific vaginitis and cervicitis were significantly more prevalent in women aged between 35 and 44. 3. The prevalences of the vaginal discharges in nonpregnant and pregnant status were 84.3% and 60.5% respectively. In nonpregnant status, nonspecific vaginits was most pervalent and during pregnancy, candida vaginitis was more prevalent than others. 4. The prevalences of the vaginal discharges in women with contraception and those without were 85.1% and 82.9% respectively. In barrier method, candida vaginitis was significantly more prevalent than others and cervicitis was significantly more prevalent than others in surgery method. 5. Vulvar itching the candida vaginitis (44.5%), foul odor in nonspecific vaginitis (19.6%), troublesome discharge in trichomonas and cervicitis (35.5%, 35.4%) were significantly more common than others. 6. Candida vaginitis in thick cheeze discharge (58.0%), nonspecific vaginitis in scanty creamy discharge (49.7), and nonspecific vaginitis in forthy discharge (55.0%) were significantly more common than others. In purulent discharge, nonspecific vaginitis and trichomonas vaginitis were significantly more prevalent than others. 7. There was a significant correlation between the vaginal pH and the casuse of the vaginal discharges. Nonspecific vaginitis was significantly prevalent in the pH value between 4.6 and 6.0, candida vaginitis in pH between 41 and 4.5, trichomonas vaginitis in pH between 5.1 and 6.0, atrophic vaginitis in pH above 6.0, atrophic vaginitis in pH above 6.0.

Identification of Numeric and Structural Abnormalities in Human Chromosomes using Oligonucleotide Probe with "Fluorescence in Situ Hybridization" (FISH)

이숙환,곽인평,성혜리,박성은,김승보,차광열 대한산부인과학회 1995 대한산부인과학회 학술대회 Vol.75 No.-

성반전 남성 1 예

이숙환,곽인평,윤태기,차광열,김현주,남윤성 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.8

저자들은 무정자증 환자에서 핵형검사상 46 , XX를 보인 성반전 남성 1 예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. The incidence of XX male reversal is approximately 1 in 20,000 to 1 in 24,000 male births, a rare disorder. The affected individuals are non-ambiguous at birth with normal male phenotype. They have a 46,XX karyotype, are chromatin positive, and may also be H-Y antigen positive. This group of patients have been key in isolating the gene controling the formation of the testis. By restriction enzyme fragmentation of the X chromosomes and the use of DNA probes, it has been shown that the majority of the XX sex-reversed males contain fragment of DNA from the short arm of the Y chromosome in the distal end of the short arm of the X chromosome. These patients have exclusively testicular tissue and develop the wolffian system while the mullerian duct regress. The external genitalia are of nonambiguous male phenotype, very similar to Klinefelter`s syndrome, but there is a more frequent association with hypospadias and an average height below normal. The testes are small and firm but bilaterally descended. The penile length is normal or slightly shorter than normal, and these patients also develop gynecomastia and hyalinization of the seminiferous tubules at puberty with incomplete pubarche. Infertility occurs secondary to hypogonadism. We have experienced a case of sex-reversed male in azoospermic patient. So we report this case with a brief review of literatures.

단일 기형아를 동반한 다태아 임신 1 례

이숙환,곽인평,윤태기,차광열,남윤성 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.4

저자들은 시험관아기 시술로 임신한 산모에서 선택적 유산술후 쌍태아 임신에서 발견된 단일 태아기형 1 례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. When complications arise in a multifetal gestation, management decisions can be very difficult for both parents and physicians because the fates of sibling fetuses are linked. The overall pregnancy outcome for a multifetal gestation appears to be worse when one of the fetuses has a congenital abnormality. The normal co-twin appears to have a higher risk of complications of prematurity because of the presence of an anomalous fetus. This information may affect parents` decisions about management options for the pregnancy. These options include expectant management, selective termination of the anomalous fetus, and termination of the entire pregnancy. We have experienced a case of multifetal pregnancy complicated by single anomalous fetus which was found after selective reduction. So we report this case with a brief review of literatures.

비만불임여성에서 발견된 흑색극세포증 1 례

이숙환,곽인평,윤태기,차광열,남윤성 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.5

저자들은 비만 불임여성에서 경부후측에 생긴 흑색극세포증 1 례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Acanthosis nigricans[AN] is a dermatopathy with a distinctive appearance that facilitates its diagnosis. Although an external condition, it is associated with a wide variety of less obvious internal conditions, either benign or malignant. Insulin resistance figures prominently in its benign associations and plays a primary role in its development. The development of acanthosis nigricans[AN] in malignant conditions remains to be explained. Acanthosis nigricans[AN] rarely requires treatment, although the underlying condition usually does. We have experienced a case of acanthosis nigricans[AN] in obese infertile woman. So we report this case with a brief review of literatures.

임신과 조기난소부전을 경험한 45 , X/47 , XXX 터너 증후군 1 예

이숙환,곽인평,윤태기,차광열,남윤성 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.7

저자들은 임신과 조기난소부전 병력이 있는 환자에서 핵형검사상 45,X/47,XXX의 터너 증후군을 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Sex chromosome monosomy occurs as monosomy X or Turner syndrome (45,X). Monosomy X is prenatally lethal in most cases, occuring in many cytogenetically abnormal spontaneous abortions. The incidence of monosomy X does not appear to be associated with increased maternal age. It is usually the paternal sex chromosome that is absent, suggesting that nondisjunction in the spermatogonium may be the underlying mechanism in the majority of cases. Monosomy Y is never observed; presumably, the presence of at leats one X chromosome is required for early embryonic development. Females with one extra X chromosome (47,XXX) may be indistinguishable from those with a normal 46,XX karyotype, although decreased fertility and an increased risk for nondisjunction may lead to reproduction problems. Females with more than three X chromosomes (48,XXXX; 49,XXXXX) have an increased incidence of physical abnormalities that may be apparent at birth, and they exhibit varying degrees of mental retardation. We have experienced a case of Turner syndrome which has experienced pregnancy and premature ovarian failure. So we report this case with a brief review of literatures.

포스타 : 산과학 ; 자궁경관 무력증: 봉합수술 부위 및 안정과 성공

조주연,곽인평,성혜리 대한산부인과학회 1994 대한산부인과학회 학술대회 Vol.74 No.-

무정자증과 관련된 45 , X/46 , XY 혼합 생식선 이상발생 1 예

이숙환,곽인평,윤태기,차광열,김현주,남윤성 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.8

저자들은 무정자증 환자에서 핵형검사상 45 , X/46 , XY를 보인 혼합 생식선 이상 발생 ( mixed gonadal dysgenesis ) 1 예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Gonadal dysgenesis traditionally has been based upon phenotypically classified syndromes in which one or both gonads become atretic or streaks. In chromosomally competent ovarian (or gonadal) failure (CCOF) the karyotypes are 46,XX or 46,XY with no cytogenetically demonstrable abnormalities. In chromosomally incompetent ovarian (or gonadal) failure (CIOF) cytogenetic abnormalities are present and include 45,X and mosaicisms (45,X/46,XX), partial deletionsof X (46,X, del[Xq], and ring X), structural abnormalities of X (46,X, i[Xq]) or Y with their mosaicisms, and mixed gonadal dysgenesis (45,X/46,XY). The gonadal phenotypes include bilateral streaks, a unilateral streak and a contralateral ovary or testis, and bilateral abdominal or scrotal testes. Somatic phenotypes range from patients with the classic Turner phenotype with short stature and sexual infantilism, though those with limited gonadal function resulting in partial or complete isosexual or heterosexual pubertal changes, to those with normal stature and sexual infantilism. We have experienced a case of mixed gonadal dysgenesis in male infertile patient with azoospermia. So we report this case with a brief review of literatures.