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대기행렬이론을 활용한 군 막사의 위생 및 복지시설 기준에 관한 연구
이안교(Lee An-Kyo),이상호(Lee Sang-Ho) 대한건축학회 2007 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.27 No.1
This study aims to modify and present criterias applying Queuing Theory on some- Toliet, Laundryroom, Lounge, P'X'-of sanitary and welfare facilities in the Military Facilities Criteria. The Military Facilities Criteria that classitfies military facilities into 11 facility groups 153 facilities and presents unit criterias is a guidance to estimate scales of military facilities in the process of planning and building military facilities. The Basic Consent of Queuing Theory is to calculate facilities' scales by controling queue incidences, which the queue occurs when users' number at the sametime exceeds service capacity in a system. So, this study draws facilities criteias using the Queuing Model to consider particularities of military facilities by modifing existing design methods properly.
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한국인 헌혈자에서 혈청학적 D-- 혈액형의 분자유전학적 특성에 관한 연구
장인순,임아현,이안교,신선미,윤경원,김재현,김황민,김영빈 대한수혈학회 2023 大韓輸血學會誌 Vol.34 No.2
Background: The Korean Red Cross has conducted serologic tests for C, c, E, e antigens and found 18 D-- donors. In this study, we performed RHCE genotyping to identify the molecular characteristics of the serologic D-- blood type in Korean blood donors. Methods: We performed RHCE-specific PCR-based electrophoresis to check the amplification pattern of each exon. Sanger sequencing was conducted to find the variants in the nucleotide sequence. We determined the RHCE genotype based on the electrophoresis and Sanger sequencing results. Results: Total eight out of 18 D-- donors were participated in this research. In the PCR-based electrophoresis tests, RHCE exons 3, 4, and 6 were not amplified in samples #4, #6, and #8. Also, sample #2 showed an abnormal band pattern of RHCE exon 9. The Sanger sequencing results showed that the nucleotide sequences of the RHCE exons 5, 7, and 8 in samples #4, #6 and #8 corresponded to the nucleotide sequences of RHD exons 5, 7, and 8, respectively, suggesting the possibility of a RHCE-RHD(3-8)-RHCE hybrid allele. The nucleotide sequences of RHCE exons 7 and 8 in sample #2 were the same as the nucleotide sequences of RHD exons 7 and 8, respectively. In samples #1, #3, #5, and #7, no specific variants known to cause D-- phenotype were found. Conclusion: RHCE genes partially replaced by the RHD genes were found in four out of eight participants and three of them were identified as RHCE*02N.07, which is known as the RHCE null allele. A further study with complete RHCE sequencing could be helpful for an understanding of the molecular mechanisms of samples in which no significant variants were identified. (Korean J Blood Transfus 2023;34:92-107)
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대한적십자사 HLA 적합혈소판 헌혈자 등록 제도의 현황
김영빈,임아현,김태은,정철호,박민희,선지영,윤경원,이안교,윤미애 대한수혈학회 2021 大韓輸血學會誌 Vol.32 No.1
HLA-matched platelet transfusion is required for patients with platelet refractoriness due to HLA alloimmunity. From 2013 to 2019, the Korean Red Cross has recruited 4,080 donors for HLA-matched platelets. The patient’s HLA information should be submitted to the Korean Red Cross in accordance with the WHO HLA serologic specificities. When HLA-matched platelets are requested, the Korean Red Cross selects the appropriate donors based on Duquesnoy’s matching grade classification (1977) and CREGs defined by Takemoto, Fuller, and Rodey (2007) and then contacts them to request blood donations. Platelets of HLA-matched donors are collected by apheresis and supplied to the hospital. To make this process more efficient, the Korean Red Cross introduced a systemic standard work procedure using a computer program for blood donor management and HLA matching. Owing to the extensive polymorphism of the HLA types, expansion of the donor pool would be required to supply HLA-matched platelets sufficiently. As the number of registered donors for HLA-matched platelets is limited, it should only be ordered when the indication criteria for its use are met. The Korean Red Cross is planning to study genotype-based matching strategies for patients with rare HLA types and receive patients’ laboratory test results from medical institutions to evaluate the effectiveness of HLA-matched platelet transfusions. (Korean J Blood Transfus 2021;32:1-10)
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