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      • KCI등재후보

        장기간의 연성 콘택트렌즈 착용이 각막두께, 각막곡률 및 각막내피세포에 미치는 영향

        박영정,이광자,박준정,정병진,이규원,Young-Jeung Park,Gwang-Ja Lee,Joon-Jeong Park,Byung-Jin Jeong,Kyoo-Won Lee 대한안과학회 2005 대한안과학회지 Vol.46 No.6

        Purpose: To investigate the effects of long-term contact lens (CL) wearing on corneal thickness, curvature, and endothelium. Methods: Using ultrasonic pachymetry, Orbscan topography and specular microscopy, we evaluated the cornea of 53 subjects who had used soft CL for more than 5 years compared with 47 controls who had never used CL. Results: There was a significant decrease of central corneal thickness in CL wearers. The difference of central corneal thickness between the two groups was 16.39 ?m. The percentage of central corneal thickness less than 500 ?m was 24.5% in the CL wearers and 12.2% in the controls. The mean corneal thickness of the CL wearers in the center and eight peripheral areas, as measured with Orbscan topography, was significantly reduced by about 7.28 to 17.87 ?m compared with that of the controls. The corneal curvature and elevation were significantly steeper in the CL wearers than in the controls but no difference in the mean corneal astigmatism was found between the two groups. Endothelial density and percentage of hexagonal cells were decreased and the coefficient of cell area variation was increased in the CL wearers compared to the controls. The percentage of endothelial cell densities less than 2500 cells/mm2 was 24.5% in the CL wearers and 4.25% in the controls. Conclusions: Long-term soft contact lens use may have a significant effect on corneal thickness, curvatures and endothelial morphology.

      • KCI등재

        양쪽머리 군날개의 수술적 치료에 대한 임상연구

        이병희,이광자,박영정,이규원.Byeong Hee Lee. MD. Gwang Ja Lee. MD. Young Jeung Park. MD. Kyoo Won Lee. MD 대한안과학회 2010 대한안과학회지 Vol.51 No.5

        Purpose: To evaluate two surgical methods-amniotic membrane transplantation (AMT) and split-conjunctival grafts (SCG)-for double-head pterygium, with regard to the postoperative outcome and recurrence rate. Methods: In a total of 16 eyes (14 patients), 7 eyes (6 patients) receiving amniotic membrane transplantation and 9 eyes (8 patients) receiving split-conjunctival grafts were compared to evaluate recurrence and complications. Results: Within the amniotic membrane transplantation group, two eyes (29%) had corneal recurrence, and 3 eyes (43%) had conjunctival recurrence. The mean follow-up period was 21.9±3.5 months, and all recurrences were on the nasal side. The average period preceding the corneal recurrences was 7.2±1.8 months. Within the split-conjunctival grafts group, the mean follow- up was 13.6±2.1 months, and neither the corneal nor conjunctival recurrences were observed. In addition, the eyes of this group were more aesthetically stable, with only one eye exhibiting pseudo-pterygium at the donor site. Conclusions: In cases of double-head pterygium without contraindication of conjunctival autograft, the split-conjunctival grafts produced fewer recurrences and showed enhanced cosmetic results, as compared to the amniotic membrane transplantation, indicating that the split-conjunctival grafts is the superior choice over amniotic membrane transplantation. J Korean Ophthalmol Soc 2010;51(5):642-650

      • KCI등재

        공막연화증에서 조직접합제를 이용한 공막이식술, 자유자가결막이식술 및 일시적 양막이식술

        최원석,이광자,박영정,이규원,Won Suk Choi,Gwang Ja Lee,Young Jeung Park,Kyoo Won Lee 대한안과학회 2011 대한안과학회지 Vol.52 No.12

        Purpose: To evaluate the surgical results and complications arising from scleral graft and free conjunctival autograft using tissue adhesive and temporary amniotic membrane transplantation as the surgical treatment for scleromalacia. Methods: Scleral graft and free conjunctival autograft using tissue adhesive and temporary amniotic membrane transplantation was performed in 20 eyes of 20 patients with scleromalacia caused by pterygium excision. The surgical results and complications arising from the procedure were monitored and analyzed through follow-up. Results: During the follow-up period of 17.6 ± 5.9 months, the wound injection and edema at the free conjunctival autograft and operation site healed in all the cases except 1 at postoperative 1 month. The stability of the ocular surface for graft transplantation was maintained at postoperative 3 months. Although a partial absorption of the conjunctival autograft induced by careless treatment occurred 2 weeks postoperative in 1 case, the ocular surface stabilized due to suitable treatment after 6 months. Although the edges of the scleral graft in 3 patients were partially absorbed 6 months postoperatively, the ocular surface stability was maintained by covering the conjunctival autografts. Conclusions: For scleromalacia patients, scleral graft and free conjunctival autograft using tissue adhesive and temporary amniotic membrane transplantation rapidly stabilized the ocular surface and presented excellent aesthetic results. J Korean Ophthalmol Soc 2011;52(12):1405-1413

      • KCI등재

        굴절성 비구면 다초점 인공수정체의 임상결과

        유성,김지현,이광자,이규원,박영정,Sung Yu,MD,Jee Hyun Kim,MD,Gwang Ja Lee,MD,Kyoo Won Lee,MD,PhD,Young Jeung Park,MD,PhD 대한안과학회 2014 대한안과학회지 Vol.55 No.7

        <b>Purpose:</b> To evaluate the clinical outcomes of patients with refractive aspheric multifocal intraocular lens (IOL) (Lentis Mplus<sup>Ⓡ LS-313) implantation. <b>Methods:</b> Sixty-eight eyes of 53 patients received refractive aspheric multifocal IOL implantation. Uncorrected visual acuity (UCVA) at a long distanc, as well as intermediate and near distances were measured on the first day, after two weeks, and during the first, third and sixth months postoperatively. Optical quality was evaluated using the Optical Quality Analysis System II (OQAS II). High-order aberrations (HOA) and patient satisfaction questionnaires were evaluated at three months post-operation. <b>Results:</b> At the six-month postoperative visit, the mean UCVA at a long, two intermediate (63 cm, 100 cm) and a near distance were 0.06 ± 0.07, 0.18 ± 0.14, 0.15 ± 0.13 and 0.11 ± 0.10 log MAR, respectively. The means of the objective scatter index, modulation transfer function (MTF) cut off value, Strehl ratio and pseudo-accommodation range measured by OQAS II were 1.20 ± 0.69, 34.15 ± 9.53 cdp, 0.17 ± 0.05 and 3.09 ± 0.25 D, respectively. HOA of 5 mm and 6 mm were each 0.61 ± 0.14 and 1.07 ± 0.20, respectively. Eighty-two percent of patients were satisfied with the postoperative results, and 71% of the patients reported that they would recommend the procedure to others, while 24% of patients reported moderate or severe visual disturbance at night. <b>Conclusions:</b> Implantation of the refractive aspheric multifocal IOLs in patients with cataracts provided excellent distant, intermediate, and near visual outcomes and high patient satisfaction as well as presbyopia correction. J Korean Ophthalmol Soc 2014;55(7):991-1000

      • KCI등재

        원추각막에서 수기 각막링 터널 생성을 이용한 인택스(Intacs;)링 삽입술의 임상 결과

        김은주,구성현,이광자,이규원,박영정,Eun Joo Kim,MD,Sung Hyun Koo,MD,Gwang Ja Lee,MD,Kyoo Won Lee,MD,Young Jeung Park,MD 대한안과학회 2012 대한안과학회지 Vol.53 No.12

        Purpose: To report the clinical results after the implantation of intrastromal corneal ring segments (Intacs<sup>?) by manual tunnel creation for the correction of keratoconus. Methods: This retrospective case series was comprised of 10 eyes of 8 consecutive keratoconic patients. Visual acuity, refractive outcome, keratometric values, anterior chamber depth, central corneal thickness, and endothelial cell density were evaluated before and at 1 month, 3 months, and 6 months postoperatively. In addition, the implanted ring segment depth was measured by anterior segment optical coherence tomography at postoperative 6 months. Any postoperative complications were also recorded. Results: Visual acuity was improved in 9 out of 10 eyes. Spherical equivalent and keratometric values were decreased in all eyes. There was no significant difference in central corneal thickness, but endothelial cell density and anterior chamber depth were slightly decreased. The depth of ring segments was almost constant at superior, middle, and inferior. There was a single case of descented implanted ring segments and 6 cases of stromal infiltration around ring segments, but visual acuity was unaffected. In addition, 1 case showed implanted ring exposure, thus the superior ring segment was removed at postoperative 4 months. Conclusions: Intrastromal corneal ring segment implantation (Intacs<sup>?) by manual tunnel creation appears to be effective in improving the visual acuity and stabilizing corneal refractive power in keratoconic patients. J Korean Ophthalmol Soc 2012;53(12):1756-1765

      • KCI등재

        회절성 난시교정용 다초점 인공수정체의 임상결과

        김지현,유성,구성현,이광자,이규원,박영정,Jee Hyun Kim,MD,Sung Yu,MD,Sung Hyun Koo,MD,Gwang Ja Lee,MD,Kyoo Won Lee,MD,Young Jeung Park,MD 대한안과학회 2014 대한안과학회지 Vol.55 No.8

        Purpose: To evaluate the clinical outcomes of patients with diffractive multifocal toric intraocular lens (IOL) implantation. Methods: Thirty-four eyes of 26 patients underwent diffractive multifocal toric IOL. Uncorrected visual acuity (UCVA) at distant, intermediate and near and residual refractive astigmatism were measured on the first day, at 2 weeks, and 1, 3 and 6 months postoperatively. Optical quality obtained using the Optical Quality Analysis System II (OQAS II), high-order aberrations (HOA) and patient satisfaction questionnaire were evaluated 3 months postoperatively. Results: At the 6 month postoperative visit, the mean UCVA at distant, intermediate (63 cm, 100 cm) and near were 0.06 ± 0.07, 0.18 ± 0.11, 0.16 ± 0.12 and 0.03 ± 0.06 (log MAR), respectively. The refractive astigmatism decreased significantly from -1.66 ± 1.04 D to -0.54 ± 0.32 D at 6 months postoperatively (<em>p</em> < 0.01). The means of objective scatter index, modulation transfer function (MTF) cut-off value, Strehl ratio and pseudo-accommodation range measured by OQAS II were 1.33 ± 0.67, 37.24 ± 9.67 cdp, 0.22 ± 0.09 and 3.08 ± 0.53 D, respectively. HOA scores for 5 mm and 6 mm were 0.30 ± 0.09 and 0.49 ± 0.15, respectively; 82.3% of the patients were satisfied with the postoperative results, 79.4% of the patients reported they would recommend the procedure to others, and 14.7% of patients reported moderate or severe visual disturbance at night. Conclusions: Implantation of a diffractive multifocal toric IOL in patients with cataract and corneal astigmatism provided excellent distant, intermediate, and near visual outcomes, good optical quality and high patient satisfaction. J Korean Ophthalmol Soc 2014;55(8):1139-1149

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