http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 이광길(KK Lee) (검색결과 5 건)
- 무료
- 기관 내 무료
- 유료
-
이국(K Lee),이윤호(YH Lee),김대현(TH Kim),박찬일(CI Park),이광길(KK Lee),노재윤(JY Ro) 대한산부인과학회 1980 Obstetrics & Gynecology Science Vol.23 No.1
결론 1. 자궁경관에 발생한 이소성 혼합육종의 1예를 보고하였다. 2. 근치자궁적출술 및 양축 골반 임파선적출술, 방사선치료, 불완전하나마 혼합약물요법같은 병합요법으로 치료한 예에서 1년간 재발없이 생존하였다. Mixed heterologous sarcoma of the uterine cervix is a rare and highly malignant tumor. A case of this type was recently experienced in a 20-year0old unmarried woman and served as the vasis of this report. The patient has been bollowed for 1 year without evidence of recurrence. Such tumors develop from the mesodermal tissue associated with mullerian duct and consist of heterologous and gifhly malignant tissues. A brief rebiew of literature is presented, especially concerning the current tend- ency of treatment : combined modality with surgery, radiotherapy and combinatation chemotherapy.
-
항암제 Cisplatin ( cis-diamminedichloroplatinum II ) 이 백서 신장에 미치는 영향에 관한 연구
김재욱(JU Kim),곽현모(HM Kwak),이광길(KK Lee),최인준(IJ Choi) 대한산부인과학회 1985 Obstetrics & Gynecology Science Vol.28 No.6
Cisplatin (cis-diamminedichloroplatinum II) is a new anticancer drug containing a heavy metal, platinum. Cisplatin shows a broad spectrum of antitumor activities in certain human cancers including gynecologic malignancies such as ovarian carcinoma. The clinical trial with cisplatin has shown moderate therapeutic benefits but also has significant toxic effects. The major toxic effects are impairment of renal function, myelosuppression, hearing loss and gastrointestinal disturbance. Of which these toxic effects, the renal toxicity is most serious dose limiting factor in clinical use. The nephrotoxicity of cisplatin has been well documented clinically, but the renal pathologic findings in patients treated with this drug have been scarce and not well demonstrated in the literature. In this study, renal toxicity is investigated in rats following a single intraperitoneal injection of cisplatin 6mg/kg, as acute experimental group and repeated treatments with cisplatin(1mg/kg twice weekly and 2mg/kg twice weekly for 11 weeks) as chronic experimental group. The results are as follows: A. Acute experimental group. 1. The mean kidney to body weight ratio is significantly greater in experimental group than controls on day 7. 2. Serum levels of BUN and creatinine rise to peak level on the 5th day and uric acid on the 7th day. On the 10th day, serum levels of creatinine and uric acid decreased to control level, but those of BUN are still greater than controls. 3. Histologic changes are characteristically confined to the corticomedullary region, straight tubules of outer zones of the medulla. Necrosis of the tubular cells is maximal on the 5th day, tubular dilatation is mostly severe on the 7th day and regeneration begins on the 10th day. B. Chronic experimental group. 1. The kidney to body weight ratio is greater than controls. 2. In rats treated with 1mg/kg of cisplatin, the mean BUN values are 6-fold greater and mean creatinine and uric acid values are 2-fold greater than controls. 3. Massive tubular dilatation in the corticomedullary region and interstitial fibrosis are noted. In conclusion, chronic use of cisplatin in cancer patients could cause irreversible renal damage.
-
-
양영호,김재욱,이광길,이성기 대한산부인과학회 1990 Obstetrics & Gynecology Science Vol.33 No.6
14예의 난소종양을 대상으로 병리조직학적 소견과 염색체변이와의 상관관계를 규명하기 위해 조직배양을 토한 염색체분석 결과와 병리조직학적 소견을 비교 관찰하여 다음과 같은 결론을 얻었다. 1. 7예의 기형종(teratoma)중 6예의 양성기형종(benign teratoma)은 모두가 정상핵형인 46,XX이었고, 1예의 미분화기형종(immature teratoma)은 peri-tetraploid의 핵형을 보였다. 2. 1예의 위점액성낭선종(pseudomucinous cystadenoma)은 정상핵형을 보였으나 1예의 장액성유두상낭선종(serous papillary cystadenoma)에서는 46,XX의 정상핵형이외에도 47,XX, +C10의 비정상세포주가 관찰되었다. 3. 3예의 장액성유두상낭선암(serous papillary cystadenocarcinoma)중 1예는 near-diploid이었고, 2예는 peri-triploid이었다. 1예의 위점액성낭선암(pseudomucinous cystadenocarcinoma)은 near-diploid이었고, 크루켄베르크 종양(Krukenberg tumor) 1예는 near-diploid 및 peri-tetraploid소견이 관찰되었다. 이상의 결과를 볼 때, 세포유전학적검사는 종양의 발생기전의 규명과 예후의 예견에 있어 유효한 것으로 사료되는 바이다. Comparative cytogenetic and histologic studies on 14 ovarian tumors were carried out. The karyotype of each tumor was compatible with nature of the tumor, showing euploidy in benign tumors ( 7 cases) and aneuploidy or polyploidy in malignant tumors (6 cases). One exception was the karyotype of one serous papillary cystadenoma, which showed both normal (45, XX) and abnormal (47, XX, +C10) cell lines. It appears that the presence of abnormal cell line, such as the one noted in this study, may be an indication that the tumor is undergoing some initial phase of malignant transformation. Though histologically benign, there may be a high risk of this type of tumor cells for malignant change probably via a clonal evolution pathway. Cytogenetic analysis of tumor cells may thus be important in defining the mechanism of carcinogenesis as well as in predicting the prognosis.
-
장영건,송찬호,김세광,이광길,조재성,윤달영,최인철,김희정 대한산부인과학회 1994 Obstetrics & Gynecology Science Vol.37 No.3
저자들은 초산부에서 임신말기에 PUPPP가 발생하였으나 질식분만 2주후에 보존적 요법으로 치유된 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. PUPPP(pruritic urticarial papules and plaques of pregnancy) is a relatively common benign dermatosis of pregnancy. It generally occurs in primigravidas. Its etiology is unknown. The clinical manifestations include erythematous urticarial papules and palques that begin on the abdomen and spread to involve the buttocks, hips, thighs, legs, and upper inner arms, but facial involvement is rare. We report a case of PUPPP syndrome in a 27 year old primigravid woman. With conservative treatment, the symptoms resolved twol weeks after delivery.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
