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      • SCIESCOPUSKCI등재

        수 종의 구강세정제에 의한 치은연하 세정이 치주염 초기치유에 미치는 영향에 관한 비교 연구

        윤기연,김강주,유형근,신형식,Yun, Gi-Yon,Kim, Kang-Ju,You, Hyung-Keun,Shin, Hyung-Shik 대한치주과학회 1998 Journal of Periodontal & Implant Science Vol.28 No.3

        The purpose of this study was to investigate the comparative effects of subgingival irrigation using some oral mouth rinses on early healing process of periodontal inflammation. The study population consisted of 13 patients with periodontal inflammation and distributed into 4 groups. Oral hygiene instruction, delicate scaling and root planing were done and then irrigated per 3 days during 2 weeks in situ with 1 of 4 solutions ; normal saline, C31G, Benzotonium chloride and tetracycline. Examination regarding probing pocket depth, plaque index, sulcular bleeding index, gingival index, gingival recession and leukocytes differential count was performed. Evaluation was made at the baseline and 2 weeks after non-surgical periodontal therapy. The results were as follows : 1. Clinical indices including probing pocket depth, plaque index, sulcular bleeding index, gingival index and gingival recession were significantly improved from baseline to 2 weeks. But there was no significant differences among 4 groups. 2. PMNs percent on leukocytes differential count was significantly decreased from baseline to 2 weeks on all groups. Those of tetracycline and C31G were significantly decreased than those of normal saline group. These results suggest that clinical indices were not different, but the decrease of inflammation were significantly different among some mouth rinses.

      • 수 종의 구강세정제에 의한 치은연하 세정이 치주염 초기치유에 미치는 영향에 관한 비교 연구

        윤기연,김강주,유형근,신형식 원광대학교 치의학연구소 1998 圓光齒醫學 Vol.8 No.2

        The purpose of this study was to investigate the comparative effects of subgingival irrigation using some oral mouth rinses on early healing process of periodontal inflammation. The study population consisted of 13 patients with periodontal inflammation and distributed into 4 groups. Oral hygiene instruction, delicate scaling and root planing were done and then irrigated per 3 days during 2 weeks in situ with 1 of 4 solutions : normal saline, C31G, Benzotonium chloride and tetracycline. Examination regarding probing pocket depth, plaque index, sulcular bleeding index, gingival index, gingival recession and leukocytes differential count was performed. Evaluation was made at the baseline and 2 weeks after non-surgical periodontal therapy. The results were as follows 1. Clinical indices including probing pocket depth, plaque index, sulcular bleeding index, gingival index and gingival recession were significantly improved from baseline to 2 weeks. But there was no significant differences among 4 groups. 2. PMNs percent on leukocytes differential count was significantly decreased from baseline to 2 weeks on all groups. Those of tetracycline and C31G were significantly decreased than those of normal saline group. These results suggest that clinical indices were not different, but the decrease of inflammation were signify cantly different among some mouth rinses.

      • Effects of Cervi Cornus Colla on Cell Cycle Regulation in Human Periodontal Ligament Cells

        Yun, Gi Yon,You, Hyung Keun 원광대학교 치의학연구소 2002 圓光齒醫學 Vol.11 No.3

        Cervi Cornus Colla (CCC)는 사슴과의 뿔로 만든 것으로 예로부터 강근건골(强筋健骨)의 효과가 있다고 알려져 왔으며, 최근 생약제재에 관한 관심의 증대로 여러 연구가 행해져 왔으나, CCC가 치주인대세포의 세포주기조절에 미치는 영향에 관해서는 아직 연구된 바 없다. 이에 본 연구는 사람 치주인대세포에 CCC를 투여하여 세포주기 조절에 미치는 영향을 평가하였다. 세포 수 측정과 MTT assay 결과, 1㎍/㎖, 10㎍/㎖, 100㎍/㎖, 1㎎/㎖의 CCC는 세포증식을 촉진시켰으며, 3일군에서는 100㎍/㎖에서 최대 증식을 나타냈으나 5, 7 일군에서는 10㎍/㎖에서 최대증식을 나타냈다. 세포증식에 가장 효과가 좋은 10㎍/㎖, 100㎍/㎖의 CCC를 치주인대세포에 투여하여 3일, 5일간의 세포주기변화를 관찰한 결과, 3, 5일군 모두에서 S기와 G2/M기의 세포주기 진행이 증가하였다. 특히 G2/M기는 농도가 증가할수록 증가하는 경향을 보였다. CCC는 농도의 증가에 따라 cyclin E 와 cdk 4의 발현을 증가시켰으며, p53, p21 과 p16INK4A의 발현은 억제하였다. 그리고, CCC는 cyclin D, cdk 6, pRb의 발현에 큰 영향을 주지 않았다. 이러한 결과는 CCC가 사람 치주인대세포의 세포주기 진행을 촉진시키며, 그 분자기전은 cyclin E 와 cdk 2, cdk 4의 발현을 증가시키고, p53, p21 과 p16INK4A의 발현은 억제하면서 이루어지는 것으로 생각된다

      • SCIESCOPUSKCI등재

        치주처치를 위한 기구들의 반복조작이 인공치관 변연부에 미치는 영향

        김재호,윤기연,최광수,유형근,신형식,Kim, Jae-Ho,Yun, Gi-Yon,Choi, Kwang-Soo,You, Hyung-Keun,Shin, Hyung-Shik 대한치주과학회 2000 Journal of Periodontal & Implant Science Vol.30 No.2

        The aim of periodontal therapy is a removal of a bacterial plaque butthe instrumentation for plaque control has two nature : removal of a bacterial plaque and increase of surface roughness. Complication of instrumentation is enable to damage to the root surface and artificial crown. Therefore this study was conducted to evaluate the effects of repeated instrumentation on the marginal portion of artificial crown. Fifteen proximal surfaces of ten extracted periodontally diseased maxillary first molars were used. The finish line was placed on the root surface, and then the crown was casted and cemented in usual manner. Three kinds of instruments: hand curet, ultrasonic scaler, and ultrasonic curet were used. After instrumentation, final polishing was done with rubber cup and pumice. And surface changes were evaluated by stereomicroscope and scannig probe microscope. Roughness was increased after instrumentation in all groups, and was decreased after polishing except ultrasonic scaler group. Roughness in the ultrasonic scaler group was lower than others, and roughness after polishing in the hand curet group was lower than others. These results indicate that polishing procedure is recommended, because periodontalinstruments increase the surface roughness and induce the irreversible damage to the marginal portion.

      • KCI등재

        학교 밖 청소년의 위기상담 경험에 관한 질적 연구

        정재철,나윤희,윤기연,류선영,나여심 인문사회 21 2023 인문사회 21 Vol.14 No.2

        The purpose of this study is to examine cases of violence among out-of-school adolescents and their crisis counseling experiences. Accordingly, this study is qualitatively studied for limited participants. A total of four participants in the study were treated as No. 2 by the court and completed compulsory counseling.The results of this study are as follows. First, the causes of violence are caused by various factors such as family indifference, personal characteristics, and social environment. Second, after crisis counseling, parents lead to personal reflection and family recovery. Third, out-of-school adolescents become an opportunity to decide on a new career path after counseling. Therefore, this study examined the new career decision-making process and new perception changes by examining the counseling process of crisis adolescents.

      • SCIESCOPUSKCI등재

        백서 두개골 결손부의 골 대체물 이식과 홍화씨 섭취 후의 치유양상

        유경태,최광수,윤기연,김은철,유형근,신형식,You, kyung-Tae,Choi, Kwang-Soo,Yun, Gi-Yon,Kim, Eun-Chul,You, Hyung-Keun,Shin, Hyung-Shik 대한치주과학회 2000 Journal of Periodontal & Implant Science Vol.30 No.1

        Many synthetic bone materials have been studied for their potential of regenerative effects in periodontal tissue. Safflower seeds have been traditionally used as a drug for the treatment of fracture and blood stasis in oriental medicines. The purpose of this study was to assess and compare the osseous responses in rat calvarial defects between bone substitutes such as calcium carbonate and bovine-derived hydroxyapatite and feeding of safflower seeds. The calvarial defects were made with 8 mm trephine bur in 24 Sprague-Dawley rats. Two graft materials were implanted in each experimental groups, whereas the control and safflower seed feeding groups were sutured without any other treatment. And then the rats of safflower seed feeding group were supplied with 3 g/day of safflower seeds. Each group was sacrificed at 4 weeks and 8 weeks. To study a histopathology related to bone healing and regeneration, Goldner's Masson Trichrome stain was done at each weeks. The tissue response was evaluated under light microscope. There were more osteoblastic activity, new bone formation, dense bony connective tissues in bovine-derived hydroxyapatite group compared to other groups at 8 weeks. The osseous defect area of safflower seed feeding group was filled with prominent fibrous tissues, where less inflammatory infiltration and new capillary proliferation. In the early phase of bone healing, safflower seed feeding reduces the inflammatory response and promotes the proliferation of connective tissue. These results suggest that natural bovine-derived HA and safflower seed feeding could enhance the regenerative potential in periodontal defects.

      • KCI등재

        『산해경』 재생신화의 상징성 연구

        정재철 ( Jaecheol Jeong ),윤기연 ( Giyeon Yun ) 사단법인 아시아문화학술원 2021 인문사회 21 Vol.12 No.5

        본 연구의 목적은 재생신화에 나타난 죽음의 원인 및 이에 대한 신화적 상징성을 파악하는 것이다. 이에 따라 본 논문은 『산해경』을 텍스트로 하여 문헌 분석 방법에 의해 연구된다. 연구 결과 재생신화의 상징성은 다음과 같이 나타난다. 첫째, 재생신화는 삶의 문제를 개선하려는 의지이다. 둘째, 신화적 상상력을 통해 인간 생명이 지속될 것을 소망한다. 셋째, 재생신화는 고된 현실을 토로하는 수단이며, 이를 통해 현실 치유기능이 강조된다. 본 연구는 사후 세계 신화가 현실과 단절성이 강조된다는 기존 연구와 달리 재생 신화는 죽음의 공포를 극복하기 위한 신화적 상상력이며, 생명 연장의 소망을 반영한 것으로 해석된다. 따라서 본 연구는 순환적 세계관의 관점으로서 재생신화는 현실과 분리된 개념이 아니라 오히려 삶과 밀접히 연관된 것으로서 현실 중심적 사고에 기반하고 있음을 밝히고자 한다. The purpose of this study is to understand the cause of death and the mythical symbolism thereof through regenerative myths. According to the Sanhaegyeong, the cause of death is not much different from everyday deaths such as murder, recklessness, resistance, and natural death. However, in myths, the continuity of life in another dimension continues as regeneration takes place. As a result of the study, the symbolism of regeneration is first, the willingness to improve life problems. Second, it is the hope that life will last. Third, regeneration is a means of expressing the injustice of reality, and it is understood that it performs the function of healing real pain through this. Therefore, this study is understood to wish for the continuity of life, contrary to the existing research view that regenerative myths mean disconnection from reality, post-renewal is a process of returning to a part of nature after death.

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