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울금이 MDA-MB-231 세포 및 DMBA로 유발된 흰쥐의 유방암에 미치는 영향
양동선 ( Dong Seon Yang ),양승정 ( Seung Jeong Yang ) 대한한방부인과학회 2013 大韓韓方婦人科學會誌 Vol.26 No.3
Objectives: Breast cancer is the most common cancer among women and has rapidly increasing rate annually. At present, western cancer therapies by surgery, radiation, and anticancer drug have not been fully effective. So many interests are given to herbal medicine on cancer treatment recently. This study was designed to investigate the effects of Curcuma longa L. (CL) on MDA-MB-231 human breast cancer cells and DMBA-induced breast cancer in rats. Methods: In this experiment, MDA-MB-231 cells were cultured in cell culture plates. 0.0625, 0.125, 0.25, 0.5, 1.0 mg/ml of CL extract were tested for their antiproliferative effects on MDA-MB-231 cells by MMT assay. And we induced breast cancer in rats. The changes in tumor`s weight, and the effects on proliferations of splenocyte and thymocyte were investigated. Results: CL showed anti-proliferative effects on MDA-MB-231 cells in proportion to concentration of the CL. DMBA-induced breast cancer in rats, tumor`s weight of the rat was not statistically significant, but showed a tendency to be reduced in the groups treated with CL. Proliferation rate of the rat`s splenocyte and thymocyte increased in proportion to CL. In breast cancer tissue, expression of ER-α was weakened proportionately to the concentration of the CL. Conclusions: These data suggest that CL can prevent the proliferation of breast cancer, then CL is useful to treat patient with breast cancer.
중성어혈 약침치료를 병행한 요골신경마비 환자 치험 4례
최은희,천혜선,이주희,류혜선,양동선,홍석,Choi, Eun-Hee,Chun, Hea-Sun,Lee, Ju-Hee,Ryu, Hye-Seon,Yang, Dong-Seon,Hong, Seok 대한약침학회 2011 Journal of pharmacopuncture Vol.14 No.4
Objectives: This study was to investigate the clinical effect of additional Jungsongouhyul Pharmacopuncture on radial nerve palsy patients. Methods & Results: The patients were hospitalized or outpatients in Department of traditional korean medical hospital, Dongshin University from 28th, Oct. 2009 to 25th, Aug, 2010. All patients were treated by additional Jungsongouhyul Pharmacopuncture. To evaluate the wrist drop and numbness of fingers, coding result, Verbal numerical scale (VNS) were used. As the result, symptoms are improved remarkably according to improvement of coding result, VNS score. Conclusions: Patients were treated during 3.5 weeks in average. All cases were excellent results by additional Jungsongouhyul Pharmacopuncture. But further studies are required to investigate exact effects.