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어린이전용도서관의 계획에 관한 연구 - 어린이대상의 도서관 유형파악과 사례분석을 중심으로 -
신현정(Shin Hyun-chung),김진균(Kim Jin-gyun) 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2
The purpose of this study was to analyze the library services for the children. In line with the fast development of the modem society, the functions of the libraries have been changed to meet the present user's needs and social requests. Apart from collecting books, the public libraries are demanded to create the knowledge and informations and to give the regional residents life-long study chances. In addition to that kinds of demands, Children's libraries is reguested services only for children. In this study, I categorize the type of the children's libraries from various points of view. And I wish to suggest the guideline of the public children's libraries in the future.
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김정용 ( Chung Yong Kim ),남양일 ( Yang Il Nam ),박실모 ( Sil Moo Park ),이중근 ( Joong Ken Lee ),신현정 ( Hyun Jung Shin ),서동진 ( Dong Jin Seo ) 대한내과학회 1972 대한내과학회지 Vol.15 No.3
Three cases of inferior vena cava obstruction. Inferior vena cava obstruction was first descrived by Schenk in 1644 and the clinical picture was described in detail by Welch and Pleasauts in 1911. The most common cause of the disease was known to be thromb
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이문호,고창순,신현정,이정상 대한핵의학회 1971 핵의학 분자영상 Vol.5 No.2
The pathogenetic mechanisms of anemia in patients with chronic liver disease were observed. Seventeen patients with moderate to advanced hepatic diseass were studied by various methods. Only patients without previous blood loss were included : 14 had cirrhosis, 2 had active chronic hepatitis, and one had inferior vena cava obstruction with associated liver cirrhosis. The followings were the results : 1.The anemia based on red blood cell count, Hb., and Ht. was found in 76.5-78.6% of the patients. 2. Red cell indices indicated that normo-macrocytic and normochromic anemia was present is the majority of the patients. 3. No evidence of megaloblastic anemia was found on the basis of the morphological examinations. 4. Serum iron, TIBC, % saturation and iron content in the bone marrow indicated that iron deficiency anemia was present in about half of the patients. 5. In the view of the erythrocyte dynamics, primary increase in the red cell destruction was ascribed to the cause of the anemia. 6. Decrease in the red cell survival time was not correlated with MCV, % saturation and S.L. ratio. Also, hemoglobin level was not correlated with MCV, % saturation and T50 Cr. Therefore, multiple causes may be involved in the pathogenesis of the anemia. 7. Anemia as determined by the red cell volume was found in only 60% of the patients. It may be possible that hemodilutional anemia is present.
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철결핍빈혈에서 Cobalt(58Co) 배설율 검사의 진단적 가치
이문호,송인경,고창순,조경삼,홍기석,신현정 대한핵의학회 1976 핵의학 분자영상 Vol.10 No.1
철결핍빈혈에서 cobalt 배설율검사의 진단적 가치를 검토할 목적으로 1974년 4월부터 1976년 4월까지 서울대학교 의과대학 부속병원 내과와 원자력병원에 입원하였던 철결핍성빈혈 22예, 재생불량성빈혈 3예, 용혈성빈혈 2예, 기타 각종질환 58예, 대조군 11예, 총계 96예를 대상으로 58CoCl2는 이용하여 cobalt 배설율검사를 시행하는 한편, 적혈구형태, 적혈구지수, 혈청철, 총철결합능, 골수철검사와 비교관찰하여 다음과 같은 결론을 얻었다. 1) 철대사와 혈액학적으로 정상이라고 생각되는 대조군의 6시간 cobalt 배설율은 평균 2.8±1.77%(1.0∼6.8%)이었으며, 24시간 cobalt 배설율은 평균 6.1±4.31%(1.9∼15.2%)였다. 2) 철결핍성빈혈의 경우에는 6시간 cobalt 배설율이 평균 18.3±5.88%(10.2∼25.0%)이었으며, 24시간 cobalt 배설율은 평균 41.8±6.83%(29.0∼54.5%)로서 대조군과 비교하여 6배이상 증가돼 있었다. 3) 골수철함량이 정상인 증례에서는 빈혈이 유무에 관계없이 6시간 및 24시간 cobalt 배설율은 모두 대조군과 유의한 차이가 없었다. 4) 6시간 cobalt 배설율과 24시간 cobalt 배설율간에는 밀접한 상관관계를 볼 수 있었으나, 실제적인 면에 있어서는 24시간 cobalt 배설율검사가 더 정확한 것으로 생각되었다. 5) 골수철함량이 정상인 증례의 24시간 cobalt 배설율은 1.2∼26.6%의 동요범위를 보인 반면, 철결핍성빈혈예의 24시간 cobalt 배설율은 29.0∼54.5%의 동요범위를 보였으며 양군간에 중복을 볼 수 없었다. 그러므로 빈혈환자에서 24시간 cobalt 배설율이 27%이상이면 철결핍성빈혈을 의심할 수 있는 것으로 생각되었다. 6) Cobalt 배설율은 골수철함량이 감소함에 따라 대체로 증가하는 경향을 보였으나 상당한 중복을 볼 수 있었고, 특히 골수철함량이 1+인 경우는 철결핍이나 골수철함량이 정상인 경우와 중복되어 통계학적으로 유의한 차이를 볼 수 없었다. 7) 골수철검사로 확인된 철결핍성빈혈의 경우, cobalt 배설율은 전예에서 증가된 반면, 적혈구형태는 40%에서, 적혈구지수는 30∼60%에서, transferrin 포화율은 70%에서 이상소견을 보였다. 이상의 성적을 종합하면 cobalt 배설율검사는 철결핍성빈혈을 진단하는데 간단하고 민감하며 정확한 검사법으로 골수철검사의 실제적인 대체검사로 이용될 수 있는 것으로 생각된다. The diagnosis of iron deficiency rests upon the correct evaluation of body iron stores. Morphological interpretation of blood film and the red cell indices are not reliable and often absent in mild iron deficiency. Serum iron levels and iron-binding capacity are more sensitive indices of iron deficiency, but they are often normal in iron depletion and mild iron deficiency anemia. They are also subject ro many variables which may introduce substantial errors and influenced by many pathologic and physiologic states. Examination of the bone marrow aspirate for stainable iron has been regarded as one of the most sensitive and reliable diagnostic method for detecting iron deficiency, but this also has limitations. Thus, there is still need for a more practical, but sensitive and reliable substitute as a screening test of iron deficiency. Pollack et al. (1965) observed that the intestinal absorption of cobalt was raised in iron, deficient rats and Valberg et al. (1969) found that cobalt absorption was elevated in patients with iron deficiency. A direct correlation was demonstrated between the amounts of radioiron and radiocobalt absorbed. Unlike iron, excess cobalt was excreted by the kidney, the percentage of radioactivity in the urine being directly related to the percentage absorbed from the gastro-intestinal tract. Recently a test based on the urinary excretion of an oral dose of 57Co has been proposed as a method for detecting iron deficiency. To assess the diagnostic value of urinary cobalt excretion test cobaltous chloride labelled with 1 μCi of 58Co was given by mouth and the percentage of the test dose excreted in the urine was measured by a gamma counter. The mean 24 hour urinary cobalt excretion in control subjects with normal iron stores was 6.1%(1.9∼15.2%). Cobalt excretion was markedly increased in patients with iron deficiency and excreted more than 29% of the dose. In contrast, patients with anemia due to causes other than iron deficiency excreted less than 27%. Hence, 24 hour urinary cobalt excretionf 27% or less in a patient with anemia suggets that the primary cause of the anemia is not iron deficiency. A value greater than 27% in an anemic subject suggests that the anemia is caused by iron deficiency. The cobalt excretion test is a simple, sensitive and accurate method for the assessment of body iron stores. It may be particularly valuable in the epidemiological studies of iron deficiency and repeated evaluations of the body iron stores.
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