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태음조위탕(太陰調胃湯)투여가 비만유전자 쥐의 식욕억제에 미치는 효과
한정석 ( Jeong Seok Han ),신영오 ( Young Oh Shin ),오재근 ( Jae Keun Oh ),금동호 ( Dong Ho Keum ) 한방재활의학과학회 2005 한방재활의학과학회지 Vol.15 No.4
Objectives : The aim of this work was to study the anorexigenic effect of Taeyuemjowui-tang(Taiyintiaowei-tang) in obese Zucker rat, assessing the mRNA of NPY and POMC in hypothalamus. Methods : Obese Zucker (fa/fa) rats were administered Taeyeumjowui-tang(Taiyintiaowei-tang) (300 mg/kg p.o.) daily for 6 weeks. The control group was administered sterile water. The weight of the whole body, food consumption, NPY and POMC expression, plasma levels of glucose;total cholesterol;triglyceride;free fatty acid, and size of the epididymal fat cells were measured. Statistical comparisons among the normal, control and sample group were done by ANOVA test. Results : Taeyuemjowui-tang(Taiyintiaowei-tang) administration in obese Zucker rats generated a reduction in food intake, triglyceride and free fatty acid. A significant decrease in NPY expression was observed. Conclusions : These results suggest that Taeyuemjowui-tang(Taiyintiaowei-tang) could be effective for the treatment of obesity as an anorexigenic agent.
홍경천 추출물 섭취가 엘리트 장거리 달리기 선수의 에너지 대사, 운동수행능력 향상 및 피로 회복에 미치는 영향
오재근 ( Jae Keun Oh ),윤진호 ( Jin Ho Yoon ),신영오 ( Young Oh Shin ),김복주 ( Bock Joo Kim ) 한국운동영양학회 2010 Physical Activity and Nutrition (Phys Act Nutr) Vol.14 No.4
Rhodiola rosea is a popular herb in traditional medical system in Europe and Asia, with a efficacy for stimulating the nervous system, decreasing depression, enhancing work performance, eliminating fatigue and preventing high altitude sickness. In this study, we aimed to investigate the effects of Rhodiola rosea to improve aerobic capacity and eliminate exercise-induced fatigue in elite long distance runners. 30 male elite college runners were participated and divided into two groups; i) Rhodiola rosea group(RG). ii) Placebo group(PG). All subjects were completed treadmill exercise protocol using GXT at before (B) and after (A) experimental treatment of four weeks. The VO2max and endurance time were measured by gas analysis and heart rate( HR) were measured by polar system at pre. post 0, post 5. post 15, post 30 min and post 60 min. Blood samples were collected to analyze blood components. The endurance time was significantly increased in RGA compared to RGB(p<.05). The blood lactate concentration were shown higher decrease rate in RGA compared to RGB(p<.05) during recovery whereas LDH were increased in RGA. And blood glucose concentration were shown higher decrease rate in RGA compared to RGB during recovery. But Other energy sources(TG, TC, MDL. LDL, creatinine) and electrolyte(Na. K. Cl) were shown no significant differences between groups. These results suggested that Rhodiola rosea can he used as ergogenic aids to improve aerobic capacity and eliminate exercise-induced fatigue.
카페인섭취가 신장성 운동 중 대퇴근 통증 감소에 미치는 효과
김태욱(Tae-Wook Kim),이정범(Jeong-Beom Lee),신영오(Young-Ho Shin),양훈모(Hun-Mo Yang),민영기(Young-Ki Min),서형석(Hyung-Seok Seo) 한국생활환경학회 2009 한국생활환경학회지 Vol.16 No.6
The purpose of this research was to determine what effect the consumption of caffeine has on alleviating muscular pain induced by repeated eccentric contraction during exercise. For this, 17 male and female college students with no prior exercise experience who do not habitually consume caffeine classified control group (male=1, female=8, age=22.67±1.15 yrs, height=165.03±5.66 ㎝, body mass=57.62±6.40 ㎏, BMI=21.48±1.60 ㎏ㆍm?²) and the experimental group with 3 ㎎ㆍ㎏?1 caffeine ingestion (male=2, female=6, age=21.20±1.40 yrs, height=165.74±5.53 ㎝, body mass=58.95±5.70 ㎏, BMI=21.67±1.81 ㎏ㆍm?²). Both carried out backward walking at a 85-88 steps per minute rhythm on a treadmill with a ?15% elevation at a speed of 3 ㎞ㆍh?1 for 30 minutes under 32±0.3℃ temperature and 33.93±0.53% humidity. The energy consumed by each of the subjects was approximately 5-7.9 ㎉ㆍmin?1 varying by different physical traits. To determine the effect of caffeine in reducing muscular pain, the changes in body mass and myoglobin levels Pre and Post the experiment were comparatively analyzed, along with the record of the perception of quadriceps muscle pain level taken every 5 minutes. The results are as follows. First, there were no statistically significant reductions in body mass between the groups (p=.709). This data suggests that an increase in sweating volume was not stimulated, and as a result side effects such as an increase in temperature, or dehydration did not occur in experimental group. Secondly, the perception of quadriceps muscle pain level in the experimental group came out low (p=.003) and is noteworthy. As a result, the potential for caffeine to prevent or reduce DOMS (delay onset muscle soreness) was proven valid. Thirdly, there were no statistically significant increase in blood myoglobin levels between the groups (p=.624). By the results of the experiment, indicate that caffeine is effective in reducing both sensual pain as well as the physiological deterioration of the muscles.
조군제,원형호,김영봉,최병선,신영오,조영걸 대한감염학회 1992 감염 Vol.24 No.3
In order to know natural course on Korean with HIV infection, we evaluated hematoimmunological state including CD4 + cells. β₂-microglobulin(Pharmacia, Sweden), complete blood count (CBC), ESR and skin delayed type hypersensitivity for 17 dead and living AIDS patients with CD4 + cells below 200/㎣. Serum β₂-microglobulin level (㎎/L) tested most recently was 5.5±2.4 totally, 6.3±2.4 at mean 4.6 months before death for 7 dead patients and 4.7±2.3 for 7 living patients. Mean CD4 + cells (/㎣) was 103±67 totally, 73±50 at 2.8 month before death for 7 dead patients and 133±71 for 7 living patients. There were not significant difference for WBC and hemoglobin, but lymphocyte count and percentage were 901±423(/㎣) and 23%, 2133±1092(/㎣) and 42%, for dead and living patient, repectively (p<0.01 and p<0.05). ESR (㎜/h) was 59±7 for dead patient and 34±24 for living patient (p<0.05). Skin delayed type hypersensitivity through Multitest CMI (Institute Merieux, France) were decreased; two patients were anergy, 6 partial anergy and 2 normal. We confirmed that serum β₂-microglobulin level increases and CD4 + cells count decreses as disease progresses, and regular CBC findings and ESR measurement may be used as a simple and easy tool for progression to AIDS if serum β₂-microglobulin and CD4 + cells measurement were not available.