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Competitive relation of wrinkling and dewetting at liquid crystal polymer flim
송성은,유필진 한국공업화학회 2015 한국공업화학회 연구논문 초록집 Vol.2015 No.1
Liquid crystal films coated on substrates undergo dewetting when adhesion force between polymer film and substrate is lower than gas-polymer surface energy. Generally, the dewetting phenomenon occurs in thin film layer less than 100nm. When thick polymer films become thinning partially, however, also generate dewetting phenomenon. When wrinkling is occurred at polymer films, the wrinkles have wavy form, so that cause partial height change. we can observe the unique patterns which co-exist wrinkling and dewetting are made because of those mutual competitive relation. In this study, we explored the wavelength transition in wrinkling and dewetting through thickness change in Liquid Crystal Polymer(LCP) film. Furthermore, as the directionality of the pattern can be tailored by the structural ordering of LCP molecules in the rubbing process of substrate we show anisotropic wrinkle patterns.
Controling competition between wrinkling and dewetting on Non-Wettable substrates
송성은,유필진 한국공업화학회 2015 한국공업화학회 연구논문 초록집 Vol.2015 No.0
Polymer thin films coated on substrates undergo dewetting when adhesion force between polymer film and substrate is lower than gas-polymer surface energy. Generally, the dewetting phenomenon occurs in thin film layer less than 100nm. When thick polymer films become thinning partially, however, also generate dewetting phenomenon.When wrinkling is occurred at polymer films, the wrinkles have wavy form, so that cause partial height change. we can observe the unique patterns which co-exist wrinkling and dewetting are made because of those mutual competitive relation. In this study, we explored the wavelength transition in wrinkling and dewetting through thickness change in Liquid Crystal Polymer(LCP) film. Furthermore, as the directionality of the pattern can be tailored by the structural ordering of LCP molecules in the rubbing process of substrate we show anisotropic wrinkle patterns.
Competitive concurrence of surface dewetting and wrinkling of liquid crystalline network films
송성은,최관현,유필진 한국공업화학회 2018 한국공업화학회 연구논문 초록집 Vol.2018 No.0
In this study, we propose polymeric thin films of liquid crystalline (LC) mesogens prepared on a non-wettable Si substrate and apply a treatment of plasma irradiation to form a thin polymerized layer at the surface. The resulting compressive stress generated in the surface region drives the formation of wrinkles, while at the same time, dipolar attraction between LC molecules induces competitive cohesive dewetting. Intriguing surface structures were obtained whereby dewettinglike hole arrays are nested inside the randomly propagated wrinkles. The structural features are readily controlled by the degree of surface cross-linking, hydrophilicity of the substrates, and the LC film thickness.
송성은,서보경,이승화,Ann Yie,이기열,조규란,우옥희,차상훈,김백현 한국유방암학회 2012 Journal of breast cancer Vol.15 No.1
Purpose: To investigate the significance of the cortex-hilum (CH) area ratio and longitudinal-transverse (LT) axis ratio and the blood flow pattern for diagnosis of metastatic axillary lymph nodes by ultrasound in breast cancer patients. Methods: From October 2005 to July 2006, we prospectively evaluated axillary nodes with ultrasound in 205 consecutive patients who had category 4B, 4C or 5 breast lesions according to the Breast Imaging Reporting and Data System-Ultrasound (BI-RADS-Ultrasound®). Among the 205, there were 24 patients who had pathologic verification of breast cancer and axillary lymph node status. For a total of 80 axillary nodes we measured the areas of the cortex and hilum of lymph nodes and calculated the area ratio. We also measured the length of the longitudinal and transverse axis of the lymph nodes and calculated the length ratio. We evaluated the blood flow pattern on power Doppler imaging and classified each lymph node into a central or peripheral pattern. Diagnostic performance was analyzed according to positive criteria for lymph node metastasis (CH area ratio >2, LT axis ratio <2, peripheral type on power Doppler imaging). Results: The sensitivity of the CH area ratio was superior to that of the LT axis ratio (94.1% vs. 82.3%, p=0.031) and to that of the blood flow pattern (94.1% vs. 29.4%, p=0.009). For specificity, all three evaluating parameters had high values (89.1-95.6%) and no significant differences were found (p=0.121). The CH area ratio had a better positive predictive value than the LT axis ratio (94.1% vs. 80.0%, p=0.030) and power Doppler imaging (94.1% vs. 66.6%, p=0.028). For the negative predictive value, the CH area ratio was superior to the LT axis ratio (95.6% vs. 86.6%, p=0.035) and the blood flow pattern (95.6% vs. 63.0%, p=0.027). Conclusion: We recommend the CH area ratio of an axillary lymph node on ultrasound as a quantitative indicator for the classification of lymph nodes. The CH area ratio can improve diagnostic performance when compared with the LT axis ratio or blood flow pattern.
그림책을 활용한 이야기나누기가 유아의 언어능력과 자아존중감에 미치는 영향
송성은,강은주 한국독서치료학회 2010 독서치료연구 Vol.3 No.1
본 연구의 목적은 유아의 언어능력과 자아존중감 향상을 위한 대안적 문학활동으로써 그림책 독후 활동으로서의 독서치료 발문을 활용한 이야기나누기가 유아의 언어능력향상과 자아존중감에 미치는 효과를 알아보는 것이다. 이러한 연구목적에 따라 서울시 성북구 S어린이집의 만3세아 20명을 대상으로 실험/통제집단으로 나누어 어휘력, 언어이해력, 언어표현력 등의 언어능력검사와 학업적, 사회적 자아, 가족, 정서적 자아 등의 자존감 검사를 각각 10명씩 동일하게 실시한 뒤 5주간 총 10회기를 통해 자존감을 높일 수 있는 주제의 그림책읽기와 이야기나누기를 독서치료적 발문에 따라 실시한 결과 그림책을 활용한 이야기나누기는 유아의 언어능력 향상에 전반적인 효과를 드러내었으나 언어이해력과 표현력에 더 유의미한 효과를 드러내었다. 그림책을 활용한 독서치료적 발문을 통한 이야기나누기는 자아존중감 향상에 전반적으로 긍정적 영향을 미쳤으나 사회적 자아 및 정서적 향상에 더 유의미한 효과를 드러내었다.
송성은,조규란,서보경,우옥희,정승필,성득제 대한영상의학회 2019 Korean Journal of Radiology Vol.20 No.3
Objective: To investigate the correlation of kinetic features of breast cancers on computer-aided diagnosis (CAD) of preoperative 3T magnetic resonance imaging (MRI) data and clinical-pathologic factors in breast cancer patients. Materials and Methods: Between July 2016 and March 2017, 85 patients (mean age, 54 years; age range, 35–81 years) with invasive breast cancers (mean, 1.8 cm; range, 0.8-4.8 cm) who had undergone MRI and surgery were retrospectively enrolled. All magnetic resonance images were processed using CAD, and kinetic features of tumors were acquired. The relationships between kinetic features and clinical-pathologic factors were assessed using Spearman correlation test and binary logistic regression analysis. Results: Peak enhancement and angio-volume were significantly correlated with histologic grade, Ki-67 index, and tumor size: r = 0.355 (p = 0.001), r = 0.330 (p = 0.002), and r = 0.231 (p = 0.033) for peak enhancement, r = 0.410 (p = 0.005), r = 0.341 (p < 0.001), and r = 0.505 (p < 0.001) for angio-volume. Delayed-plateau component was correlated with Ki-67 (r = 0.255 [p = 0.019]). In regression analysis, higher peak enhancement was associated with higher histologic grade (odds ratio [OR] = 1.004; 95% confidence interval [CI]: 1.001–1.008; p = 0.024), and higher delayed-plateau component and angio-volume were associated with higher Ki-67 (OR = 1.051; 95% CI: 1.011–1.094; p = 0.013 for delayed-plateau component, OR = 1.178; 95% CI: 1.023–1.356; p = 0.023 for angio-volume). Conclusion: Of the CAD-assessed kinetic features, higher peak enhancement may correlate with higher histologic grade, and higher delayed-plateau component and angio-volume correlate with higher Ki-67 index. These results support the clinical application of kinetic features in prognosis assessment.