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- 저자 : 배상은(Sang-Eun Bae) (검색결과 57 건)
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배상철(Sang Cheol Bae),김동욱(Dong Yook Kim),김태환(Tae Hwan Kim),전재범(Jae Bum Jun),정성수(Sung Soo Jung),이인홍(In Hong Lee),유대현(Dae Hyun Yoo),김성윤(Seong Yoon Kim),이은영(Eun Young Lee),장성렬(Sung Yeoul Chang) 대한내과학회 1997 대한내과학회지 Vol.52 No.1
N/A Objectives: Nitric Oxide(NO) is a toxic, inorganic, gaseous free radical produced during the metabolism of L-Arginine by NO synthase(NOS). It has been implicated in a rapidly growing number of physiological and pathophysiological processes such as cytotoxic effects against microbes and tumor cells, blood vessel dilation and neurotransmitter. Recently there is growing evidence implicating NO in immune regulation, inflammation, autoimmunity, and arthritis. We performed this study to determine a role for nitric oxide in inflammatory arthritis especially rheumatoid arthritis(RA). Methods: We measured (D the concentrations of nitrite, a breakdown product of nitric oxide, in serum and synovial fluid from patients with RA and osteoarthritis(OA) and in the serum of controls ② the concentrations of nitrite in the supernatant of cultured synovial tissue with RA and OA and ③ determined whether human chondrocytes and synoviocytes can synthesize nitric oxide and if so, how production is regulated by cytokines and antirheumatic drugs. Results: 1) Serum nitrite concentrations in patients with RA and OA were higher than in controls. In both disease groups synovial fluid nitrite was higher than serum nitrite. Serum and synovial fluid nitrite concenrations in RA were higher than those in OA. However, those findings are not statistically significant. 2) Although these findings are not statistically significant, the concentration of nitrite in the supernatant of cultured synavial tissue with RA was higher than that in OA. 3) IL-l5 and TNF-a induced the biosynthesis of NO by chondrocytes and synoviocytes. IGF-1 and TGF-5 failed to provoke the production of NO. The biosynthesis of NO required an induction period of approximately 6 hours and was inhibited by L- NMMA and cycloheximide. Dexamethasone, indomethacin, gold sodium thiomalate and methotrexate had no effect on the induction of NO biosynthesis. Conclusion: These results suggest a role for nitric oxide as an inflommatory mediator in inflammatory arthritis.
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사격 스포츠 참여 노인의 정신건강과 생활만족에 관한 연구
배상운 ( Sang Woon Bae ),강성웅 ( Sung Woong Kang ),홍지은 ( Ji Eun Hong ),김규호 ( Gyu Ho Kim ) 고려대학교 스포츠과학연구소 2010 스포츠科學論叢 Vol.17 No.-
본 연구는 사격 스포츠 참여집단과 다른 스포츠 참여집단 그리고 스포츠 비 참여집단간의 정신건강 및 생활만족의 차이를 규명함으로써 노인의 정신건강과 생활만족에 사격 스포츠가 부합되는지를 밝히는데 목적이 있다. 본 연구의 조사대상은 사격 스포츠 참여 노인 85명과 다른 생활체육 참여자 또는 비참여자 160명 등 총 245명을 표집하였으며, 누락된 자료와 불성실한 자료로 판단되는 데이터를 제외한 227명의 자료를 최종 분석 자료로 사용하여 다음과 같은 결과를 도출하였다. 첫째, 정신건강 차이검증에 있어서, 사격 스포츠 참여 집단이 다른 스포츠 참여 집단과 스포츠 비 참여 집단보다 긍정적 정신건강이 더 높은 것으로 나타났으며 부정적 정신건강에서는 집단 간 차이가 없는 것으로 나타났다. 둘째, 생활만족 차이검증에 있어서, 사격 스포츠 참여 집단이 가장 높은 긍정적 생활만족을 나타냈으며, 스포츠 비 참여집단이 가장 낮은 긍정적 생활만족을 나타냈다. 그러나 부정적 생활만족에서는 차이가 없는 것으로 나타났다. 셋째, 정신건강과 생활만족의 관계 검증에 있어서, 긍정적 생활만족에 대하여 긍정적 정신건강이 정(+)적 영향을 미치는 것으로 나타났으며, 부정적 생활만족에 대하여 긍정적 정신건강은 부(-)적 영향을 미치는 것으로 나타났고 부정적 정신건강은 정(+)적 영향을 미치는 것으로 나타났다. 그러므로 이상의 결과를 종합하여, 사격 스포츠 참여는 신체적 부담이 적고 정신집중을 많이 요구하는 스포츠라는 특성 때문에 다른 종목의 생활체육 참여나 생활체육 비 참여보다 사격 스포츠 참여는 노인의 긍정적 정신건강에 큰 도움을 주며, 이러한 긍정적 정신건강은 결국 긍정적 생활만족에 영향을 미쳐 노년기에 윤택한 삶을 누릴 수 있도록 하는데 부합하는 스포츠라고 결론 내린다. The purpose of the study is to investigate the relation between elder`s mental health and life satisfaction through the shooting leisure sports. The study involved a group of shooting sports and other sports groups, and non-participating group. The study examined mental health and life satisfaction differences among those groups to clarify the match The subjects of the study involved 85 shooting sports participating and 160 other sports participating and non-sports-participating elderly. The data have been sampled in total of 245, the data which is missing and judged as insincere, omitted and used 227 questionnaires in the final analysis. The study conducts following results: First, the differences in mental health, shooting sports participating group have positive mental health than other sports participating group and non-participating group, and there were no significant differences in negative mental health Second, the differences in life satisfaction, the shooting sports participating group appeared concretely the highest and non-participating group appeared the lowest among the participants. However, there were no significant differences in negative mental health Third, the relationship between mental health and life satisfaction appeared as the positive mental health affect to positive life satisfaction. And negative life satisfaction for the positive mental health was negatively affected and negative mental health was positively affected. Therefore, the results suggest that the shooing sports which is fewer physical and mental burden compare to other sports is great for elderly to practice mental focus and assist them to have positive mental health. The study conclude that participating sports impact positively to participant`s mental health, and mental health of old age eventually lead elderly to live a comfortable life.
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중성 수용액에서 폴리피롤의 전기화학적 성장시 발생하는 점탄성 변화에 미치는 음이온 효과
배상은,이승용,백세환,김영상,이치우,Bae Sang-Eun,Lee Seung-Yong,Paek Se-Hwan,Kim Young-Sang,Lee Chi-Woo 한국전기화학회 1999 한국전기화학회지 Vol.2 No.2
수용액에서뿐만 아니라 유기용매에서도 폴리피롤이 전기화학적으로 전극표면에서 잘 성장한다는 많은 연구가 보고되어 있다. 근래에 들어서 폴리피롤을 산업적으로 사용하려는 노력이 많지만 기본적인 물리적 그리고 화학적 성질은 알려지지 않은 것이 많다. 특히, 폴리피롤의 미세유변학적 성질은 전기화학적 수정결정 진동자법이 알려지기 이전까지 거의 무시되어 왔다. 본 논문에서는 중성 수용액에서 폴리피롤을 전기화학적으로 성장시킬 때 발생하는 폴리피롤의 점탄성도 변화를 전기화학적 수정결정 진동자법으로 조사하였다 그 결과 $KPF_6$ 와 $KCIO_4$중성 수용액에서 합성된 막이 $KCI,\;KNO_3,\;KBr,\;KBF_4,\;K_2SO_4$, sodium tosylate(NaOTs), sodium dodecyl sulfate (SDS) 각각의 중성 수용액에서 합성된 막보다 점탄성도가 더 크며 폴리피롤의 전극 표면에서의 성장 속도가 SDS중성 수용액에서 가장 빠르다는 것을 발견하였다. 또한 중성 수용액에서 합성한 폴리피롤이 비완충 수용액에서 합성한 막보다 탄성도가 더 컸다 A large number of works have been Performed to understand the electrochemical growth of Polypynole on conducting substrates in aqueous as well as in nonaqueous solutions. Recently most researches with Polypyrrole have tended to be directed toward technological applications, but many fundamental physical and chemical properties of Polypyrrole remain unknown. In Particular, microrheological Property of polypyrrole has been largely neglected until the advanced electrochemical quartz crystal microbalance technique was introduced recently. To study anion effects on microrheolosical Property of Polypyrrole, we investigated changes in viscoelasticity of Polypyrrole during electrochemical growth in neutral aqueous solutions by means of in siか electrochemical quartz crystal oscillator method. The results showed that the films of Polypyrrole synthesized in $KPF_6\;and\;KCIO_4$ were more viscoelastic than the ones in $KCI,\;KNO_3,\;KBr,\;KBF_4,\;K_2SO_4$, sodium tosylate (NaOTs), and sodium dodecyl sulfate (SDS). The growth rate of Polypyrrole in SDS was faster than that in the others utilized. Polypyrroles synthesized in buffered neutral solutions were more elastic than those in unbuffered neutral solutions.
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남성 불임에 관한 실험연구 동향 분석 -학위논문 중심으로-
배상은 ( Sang Eun Bae ),김희정 ( Hee Jeong Kim ),이승열 ( Seung Yeol Lee ),김흥수 ( Heung Su Kim ),김철수 ( Chul Soo Kim ),하인혁 ( In Hyuck Ha ),이진호 ( Jin Ho Lee ) 대한한방부인과학회 2014 大韓韓方婦人科學會誌 Vol.27 No.1
The tendency of experimental studies on the male infertility wasanalyzed through focusing on domestic theses for a degree to indicate the hereafterdirection for its study in oriental herbal medicine. Methods: 35 domestic theses for a degree published after 2003 were analyzed. And theses were classified by year, study design, degree and subjects. Results: The followings are the results of this study. 1. 35 theses were reviewed. 11 master dissertations and 24 doctorate dissertations2. In the annual publishing tendency, the number of theses began to increase from2003 and the theses have been published actively from 2005. 3. Classified by study design, 19 in vitro & in vivo and 16 in vitro experimentalstudies were performed. 4. In the medication and prescription, the studies with single medication were 32, and prescription were 3. In the studies with single medication, four studies onGinseng Radix (人蔘) were the most. 5. In theses related to single medication, BoYang-Yak was most prefered, followedBoYeum-Yak, BoKi-Yak, SabJung-ChukNyo-JiDae-Yak. 6. Analysed 35 theses by subject, concentrational experiments were 23, periodicalexperiment were 3, concentrational & periodical experiment was 1. 7. In theses related to herb medication, the themes were Body & testicular weight, sperm parameters, testosterone level, CREM mRNA level & CREM protein, seminiferous tubule and antioxidant activity. 8. Related to herb medication`s antioxidant activity efficacy were 7 theses. Conclusions: If there are more diverse studies on medication, prescription, external treatment methods and experiment methods in the future, this will bevery helpful for the clinical treatment of male infertility.
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Si(111)-H 표면의 전기화학적 제조에 관한 전기화학적 주사터널링현미경법 연구
배상은,이치우,Bae, Sang-Eun,Lee, Chi-Woo 한국전기화학회 2002 한국전기화학회지 Vol.5 No.3
Electrochemical scanning tunneling microscopy was employed to study the evolution of surface morphology during electrochemical preparation of Si(111)-H from Si(111) oxide. Anodic dark current of cyclic voltammogram in 0.2M $NH_4F$ solution (pH 4.7) decreased as the number of cycles increased and remained nearly constant after the second cycle. Then, the Si(111) oxide was entirely stripped, which was followed by H termination on the Si(111) surface. Hydrides at kink and step sites were etched more rapidly than on the terrace, which remained triangle pits with [112] oriented steps where existed stable monohydride. Then, triangle pits deepened. During chronomamperometry at 0.4V anodic dark current shoulder appeared and decreased slowly, indicated the stripping of Si(111) oxide and the formation of stable (112) oriented steps with monohydride. Additionally, the etching mechanism of Si(111)-H in 0.2M $NH_4F(pH 4.7)$ solution at +0.4V was discussed. 묽은 불산용액에서 Si(111) 산화막 (SiOx) 표면을 전기화학적으로 에칭할 때 생성되는 Si(111)-H 표면변화를 전기화학적 주사터널링현미경을 사용하여 조사하였다. pH가 4.7인 0.2M $NH_4F$ 용액에서 순환전압전류곡선은 순환 횟수가 증가할수록 양극 암전류가 감소하였고 두 번 이상 순환한 시료의 암전류는 일정한 형태의 전압전류곡선을 나타냈다. 이때 표면은 모든 SiOx층이 벗겨져 수소말단화된 구조를 가졌으며, 그 이후 순환에서는 생성된 Si(111)-H 표면의 이중 수소결합이 없어지는 step-flow반응이 일어나, 표면이 단일수소결합을 가지는 [112]모서리의 안정한 삼각형 모양을 나타냈으며 또한 생성된 삼각형 흠의 깊이가 점차 깊어졌다. 일정전압법에서는 초기에 큰 양극 암전류 최고 값을 나타낸 후, 시간에 따라 양극 암전류가 감소하였다. 양극 암전류 최고 값 후. 표면의 모든 SiOx가 벗겨졌으며 이후 양극 암전류는 작은 값을 띠면 조금씩 더 낮아졌다. 이 낮아지는 양극 암전류 역시 이중수소 결합의 step-How반응에 안정한 단일수소결합의 [112]모서리 생성에 의해 나타난다. pH 4.7인 0.2M $NH_4F$용액중의 Si(111)-H표면에 +0.4V를 가할 때 진행되는 에칭반응의 메커니즘에 관해서 논하였다.
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