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약물운반체 개발을 위한 각종 인지질 베시클들의 비교 제조 및 특성실험
이충희,임근풍,박홍식,정관영,최명언 ( Choong Hee Lee,Keun Poong Lim,H . S . Park,Kwan Young Jung,Myung Un Choi ) 생화학분자생물학회 1986 BMB Reports Vol.19 No.4
In order to develop an efficient drug-delivery system, various phospholipid vesicles were prepared and their basic properties were compared. Phospholipids used for vesicle preparation were extracted from rat brain by Folch method and separated by DEAE-cellulose and silicic acid column. Some of phospholipids were also synthesized from egg phosphatidylcholine by means of the phospholipase D. Small unilamellar vesicle, large unilamellar vesicle, and plurilamellar vesicle were prepared by the methods of sonication, reverse-phase evaporation, and ether emulsification respectively 6-Carboxyfluorescein techniques were used for estimation of the encapsulation capacity and permeability of the prepared vesicles.
구경민(K.M.Gu),노영희(Y.H.Noh),김동영(D.Y.Kim),홍도관(D.K.Hong),안찬우(C.W.Ahn),한근조(G.J.Han),박홍식(H.S.Park) 대한기계학회 2003 대한기계학회 춘추학술대회 Vol.2003 No.11
On this study, we improved the efficiency applying algorithm that is repeatedly using orthogonal array in diserete design space and filling a defect of gradient method in continuous design space. we showed optimal ply angle that maximized lst natural frequency of CFRP laminated composite cantiever plate by esch aspect ratio. A finite element analysis on the CFRP laminated composite cantilever plate using orthogonal array is carried out, and the results are compared with those obtained by modal testing.