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박윤상,조유리,Eun Ju Cho,김윤준 대한간학회 2015 Clinical and Molecular Hepatology(대한간학회지) Vol.21 No.2
Background/Aims: Overlap syndrome of autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC) (AIH-PBC overlap syndrome) is a rare disease that has not been clearly characterized in Korean patients. This study investigated the clinical features of AIH-PBC overlap syndrome compared with those of AIH and PBC alone. Methods: This retrospective cohort study included 158 consecutive patients who were diagnosed as AIH (n=61), PBC (n=81), or AIH-PBC overlap syndrome (n=9) based on the Paris and the International Autoimmune Hepatitis Group (IAIHG) criteria from 2001 to 2011 in Korea. We compared the clinical features of these three groups retrospectively, including their biochemical characteristics, treatments, responses, and clinical outcomes. Results: The AIH-PBC overlap syndrome patients exhibited biochemical characteristics of both AIH and PBC, and showed a similar response to ursodeoxycholic acid (UDCA) monotherapy as for the PBC patients. However, the response of AIH-PBC overlap syndrome patients to UDCA and steroid combination therapy was worse than the response of AIH patients to steroid-based therapy (P=0.024). Liver cirrhosis developed more rapidly in AIH-PBC overlap syndrome patients than in AIH patients group (P=0.013), but there was no difference between AIH-PBC overlap syndrome patients and PBC patients. The rates of developing hepatic decompensation did not differ significantly between the groups. Conclusions: The AIH-PBC overlap syndrome patients exhibited a worse response to UDCA and steroid combination therapy and a faster cirrhotic progression compared with AIH patients. (Clin Mol Hepatol 2015;21:150-157)
박윤상,최민규,Hossein Daneshpajooh,Timo Scholehwar,Eberhard Hennig,KenjiUchino 한국전기전자재료학회 2021 전기전자재료학회논문지 Vol.34 No.3
IEEE Standard on Piezoelectricity has been utilized for decades though it has shown significant issues that prevent researchers from obtaining accurate materials coefficients. To resolve these issues, our research group recently proposed partial electrode (PE) method. PE method utilizes samples that consist of the center part covered with electrode, and the side part either covered or not covered with electrode for obtaining both intensive and extensive elastic parameters. In this review, we introduce our PE method, along with physical phenomenology and background, such as issues of IEEE standard, to bolster readers understanding of needs for developing new measurement method that can compensate the standard method. It is shown that development of the PE method not only provides technological benefits, but also gives scientific importance for the piezoelectric research community from its extremely high data accuracy.