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노기탁,이경주,손희정,이경한,허원석,고병성,한은미,배영아 영남대학교 의과대학 2016 Yeungnam University Journal of Medicine Vol.33 No.1
Pulmonary epithelioid hemangioendothelioma (PEH) is a rare, low-to-intermediate malignant tumor of endothelial origin. Computed tomography (CT) findings of PEH demonstrate multiple small bilateral nodules; however, to the best of our knowledge, there were no reports on PEH coexisting with other malignancies. Here, we reported on a case involving PEH in a patient with colon cancer and breast cancer which was misconceived as pulmonary meta- stasis. A 63-year-old woman who suffered from constipation for 2 weeks visited our hospital. Colonoscopy showed a large mass with obstruction on hepatic flexure. The histological diagnosis was adenocarcinoma of the ascending colon. Multiple nodules in both lungs and breast were observed on a chest CT scan. A core biopsy of a breast nodule was performed and a diagnosis of invasive ductal carcinoma of the left breast was made. Pulmonary nodules observed on the chest CT scan was considered as pulmonary metastasis from colon or breast cancer. Laparoscopic right hemicolectomy was performed. At the same time, wedge resection of the lung was performed and pathological diagnosis was PEH. Radiologic features of PEH were difficult to distinguish from lung metastasis. Therefore the author reported a rare case involving PEH in a patient with primary malignancy of colon and breast.
최양호,노영재,성기탁,장대수 한국자연보호학회 2013 한국자연보호학회지 Vol.7 No.2
The distribution of dissolved oxygen (DO) and its variability in Chunsu Bay were studied. Monthly hydrographic survey and realtime monitoring for water quality conditions were carried out in study area. Vertical distribution of DO shows the formation of hypoxia in the bottom water in the vicinity of the artificial dyke and net cage aquaculture site in summer. Annual mean of DO was 8.4 mg/l, with minimum monthly mean of 6.9 mg/l in July and maximum of 11.2 mg/l in March. Temporal variation of DO at bottom water around the net cage aquaculture site shows pronounced oscillatory characteristics with range of 0.5~7.0 mg/l. Coherency analyses between the tidal range and DO concentration shows that variation of DO is significantly coherent with tidal range at semi-diurnal period with 1~3.5 hours phase-lags. A simple DO budget model was set up to account for the formation of the extreme hypoxic conditions in Chunsu Bay. The governing equation is based on the mass-balance for kinetic process with simplified parameter of source and sink terms of DO. the source term is represented by replenishment through the vertical and horizontal diffusion and mixing. the sink terms comprise function of sediment oxygen demand (SOD) and carbonaceous biochemical oxygen demand (CBOD). The result of numerical solution indicates the dominant role of SOD as the overriding factor against the oxygen supply.
고병성,김상중,유경화,이경한,노기탁,허원석 이화여자대학교 의과학연구소 2015 EMJ (Ewha medical journal) Vol.38 No.3
The incidence of tuberculosis (TB) had gradually been declining all over the world, but in recent years, TB has been increasing due to the spread of the human immunodeficiency virus (HIV). When immune-suppression status deteriorates further, extrapulmonary TB generally appears more often. Abdominal TB is one type of extra-pulmonary TB, which may involve the gastrointestinal tract, peritoneum, lymph nodes or solid viscera. We encountered a case who had initially been diagnosed as having abdominal TB, had progressed to acute respiratory distress syndrome and was eventually confirmed as having developed acquired immune deficiency syndrome. In cases of coinfection of TB and HIV, it is reported that immunological responses become poor and complications with higher morbidity frequently occur. Therefore, the Korean guidelines for TB should be revised to ensure whether HIV infection exists in TB patients.
The Prevalence of Sarcopenia in Korean Hospitalized Elderly
허원석,백현욱,강주희,박주상,박상종,장은정,박상운,김상중,고병성,노기탁,이경한,최정아 대한노인병학회 2015 Annals of geriatric medicine and research Vol.19 No.4
Background: Sarcopenia is a syndrome characterized by the progressive loss of skeletal muscle mass and muscle strength. Although data exist on the prevalence of sarcopenia among the community-dwelling elderly, there is no systematic research on hospitalized elderly patients in Korea, in accordance with the newly developed criteria. Methods: A cross-sectional study was conducted at the Daejin Medical Center, Bundang Jesaeng Hospital, Korea, from May 2013 to March 2015. In this study, we evaluated the levels of hemoglobin, total cholesterol, serum albumin, serum prealbumin, and serum zinc. Handgrip strength was measured with a hand grip dynamometer (FT-7110). Furthermore, the skeletal muscle mass was measured by bioelectrical impedance analysis (BIA). Sarcopenia was defined by skeletal muscle mass as measured with BIA, according to the Asian Working Group for Sarcopenia. Results: Of the hospitalized elderly subjects, 40 (46.5%) had a definite diagnosis of sarcopenia and 46 (53.5%) had no sarcopenia. The prevalence of sarcopenia of the subjects was higher in males than females (males, 46.9% vs. females, 46.3%). The correlation analysis showed that the score of skeletal muscle index (SMI) was negatively correlated with age; whereas, it was positively correlated with the BMI, body weight, and serum prealbumin level. Conclusion: The results of the study showed that sarcopenia was associated with several factors, including age, BMI, serum prealbumin level, among the study subjects. Sarcopenia can be used as a sensitive predictive marker for prognosis of the hospitalized elderly.